Editing Kynurenine
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[[File:Kynurenine a role ME CFS.jpg|alt=Kynurenine: a role in ME? Kynurenine is "a key metabolite in the tryptophan metabolism, and serves several roles in the immune system and inflammation" - Open Medicine Foundation |border|right|frameless]] | [[File:Kynurenine a role ME CFS.jpg|alt=Kynurenine: a role in ME? Kynurenine is "a key metabolite in the tryptophan metabolism, and serves several roles in the immune system and inflammation" - Open Medicine Foundation |border|right|frameless]] | ||
'''Kynurenine''' is an [[amino acid]] that is produced in the body by the metabolism of the essential amino acid [[tryptophan]].<ref>{{Cite web|url=https://www.merriam-webster.com/medical/kynurenine | title = Medical Definition of KYNURENINE|website=Merrian-Webster Dictionary|language=en|access-date=2019-11-30}}</ref><ref name="pubchem">{{Cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/Kynurenine | title = PubChem Compound Summary for CID 846, Kynurenine | last = National Center for Biotechnology Information | first = | authorlink = | date = 2021 | website = PubChem Database|language=en|archive-url=|archive-date=|url-status=|access-date=2020-01-19}}</ref> | '''Kynurenine''' is an [[amino acid]] that is produced in the body by the metabolism of the essential amino acid [[tryptophan]].<ref>{{Cite web|url=https://www.merriam-webster.com/medical/kynurenine | title = Medical Definition of KYNURENINE|website=Merrian-Webster Dictionary|language=en|access-date=2019-11-30}}</ref><ref name="pubchem">{{Cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/Kynurenine | title = PubChem Compound Summary for CID 846, Kynurenine | last = National Center for Biotechnology Information | first = | authorlink = | date = 2021 | website = PubChem Database|language=en|archive-url=|archive-date=|url-status=|access-date=2020-01-19}}</ref> | ||
==ME/CFS == | ==ME/CFS == | ||
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==Uppsala trial, Sweden == | ==Uppsala trial, Sweden == | ||
In April 2020, the Open Medicine Foundation announced a pilot treatment trial of kynurenine for [[ME/CFS]].<ref name="maymomentum">{{Cite web|url=https://www.omf.ngo/maymomentum/ | title = #May Momentum 2020 | last = Open Medicine Foundation | first = | authorlink = Open Medicine Foundation | date = May 2020 | website = Open Medicine Foundation|language=en-US|archive-url=https://web.archive.org/web/20200621215257/https://www.omf.ngo/maymomentum/|archive-date=2020-06-21|url-status=dead|access-date=2020-05-01}}</ref> Dr [[Jonas Bergquist]] will be running the trial.<ref name="omf-trial-2020">{{Cite web|url=https://www.omf.ngo/2020/04/26/kynurenine-clinical-trial-for-me-cfs/ | title = Kynurenine Clinical Trial for ME / CFS | last = Open Medicine Foundation | first = | authorlink = Open Medicine Foundation | date = 2020-04-26 | website = Open Medicine Foundation|language=en-US|archive-url=|archive-date=|url-status=|access-date=2020-05-05}}</ref> | In April 2020, the Open Medicine Foundation announced a pilot treatment trial of kynurenine for [[ME/CFS]].<ref name="maymomentum">{{Cite web|url=https://www.omf.ngo/maymomentum/ | title = #May Momentum 2020 | last = Open Medicine Foundation | first = | authorlink = Open Medicine Foundation | date = May 2020 | website = Open Medicine Foundation|language=en-US|archive-url=https://web.archive.org/web/20200621215257/https://www.omf.ngo/maymomentum/|archive-date=2020-06-21|url-status=dead|access-date=2020-05-01}}</ref> Dr [[Jonas Bergquist]] will be running the trial.<ref name="omf-trial-2020">{{Cite web|url=https://www.omf.ngo/2020/04/26/kynurenine-clinical-trial-for-me-cfs/ | title = Kynurenine Clinical Trial for ME / CFS | last = Open Medicine Foundation | first = | authorlink = Open Medicine Foundation | date = 2020-04-26 | website = Open Medicine Foundation|language=en-US|archive-url=|archive-date=|url-status=|access-date=2020-05-05}}</ref> | ||
=== Trial type === | === Trial type === |