Vitamin B6 (pyridoxal-5'-phosphate, P5P, PLP, pyridoxine, pyridoxamine) is a co-factor in amino acid metabolism, the folate cycle, and the biosynthesis of neurotransmitters, including dopamine, GABA, melatonin, norepinephrine, and serotonin.
Role in the body[edit | edit source]
Vitamin B6 is a cofactor for diamine oxidase, the enzyme that breaks down histamine. It is also a cofactor of histidine decarboxylase, the enzyme that catalyzes the decarboxylation of histidine to form histamine.
Chronic fatigue syndrome[edit | edit source]
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See also[edit | edit source]
References[edit | edit source]
cofactor - A substance that acts with another substance to bring about certain effects. In biochemistry, a cofactor is a molecule that is necessary for a given biochemical reaction, but is not an enzyme or substrate of the reaction.
enzyme - a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.
chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.