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Probiotics are microorganisms that are believed to provide health benefits when consumed.

Health effects[edit]

  • Some bacteria species have been shown to inhibit pathogens in the gut[1] through competition or by producing their own antibiotics.
  • Probiotics can reduce histamines levels, or increase them.[2]
  • CFS Remission - Survey of Probiotics Responses[3]


Probiotics should be taken with or immediately before a meal, ideally with 1-2% milk.[4].

Evidence for Commercial Probiotics[edit]


E. Coli Nissle 1917[5]


E. Coli G1-G10 6 species[6]

Prescript Assist[edit]

Prescript Assist is a commercial probiotic containing 28 soil based bacteria.[7]


Miyarisan is a Japanese probiotic containing clostridium butyricum,[8] a species that consumes lactic acid and produces butyrate.[9]

Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3[edit]

Clostridium butyricum, Streptococcus faecalis, Bacillus mesentericus[10]


Bifidobacterium infantis 35624[11][12]


Lactobacillus Rhamnosus GG[13]


Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus rhamnosus, Lactobacillus salivarius, Lactobacillus gasseri[14]

See also Bifidobacteria


Bacillus clausii [15]


Lactobacillus casei Shirota


Lactobacillus casei Danone


Enterococcus faecium SF 68[16]


Lactobacillus reuteri[17][18] = Produces B12

Suspected to be effective but lacking studies[edit]

GeneralBiotics Equilibrium[19] 115 strains - none are lactobacillus or bifidobacteria.

Commercial probiotics without evidence[edit]

These are likely harmful because they are known to kill E.Coli that is very low in CFS patients.

Common Yogurts[edit]

Lactobacillus Acidophilus[20]

Typical Probiotics sold in Health Food Stores[edit]

Lactobacillus Acidophilus[20] - often kill off the bacteria that was greatly reduced by CFS. Further unbalance the microbiome.


Not sufficient research published[21]

GcMAF Bravo[edit]

"“Streptococci, lactobacilli, bifidobacteria, lactococci, yeasts” - no research, no details of strains[22]

Species and Strains[edit]

Evidence for specific strains[edit]


Main article: Bifidobacteria

Cost per Billion CFU can vary from 1 cent to $1.62.[23] A recent study found 15/16 commercial offerings in California were mislabeled (i.e. different strain than listed).[24]

Bifidobacterium infantis 35624[edit]

One study found that 6-8 weeks of Bifidobacterium infantis supplementation reduced C-reactive protein, TNF-alpha and IL-6 levels in CFS patients.[25] Another found that B. infantis boosted serotonin levels in the brain.[26]


Main article: Lactobacillus

Learn more[edit]

See also[edit]


  1. Hindawi - List of probiotics tested on different eukaryotic pathogens
  2. CFS Remission - Probiotics and histamines
  3. CFS Remission - Survey of Probiotics Responses
  4. CFS Remission - When to take probiotics? - an actual study
  5. CFS Remission - My favorite probiotic: E. Coli Nissle 1917 (Mutaflor)
  6. CFS Remission - Symbioflor-2: Another E. Coli Probiotic
  7. CFS Remission - Prescript-Assist Broad Spectrum Probiotic Prebiotic Complex
  8. CFS Remission - Miyarisan clostridium butyricum revisited
  9. Reference needed
  10. CFS Remission - A new probiotic: Advanced Orthomolecular Research AOR, Advanced Series, Probiotic-3
  11. CFS Remission - Align – Bifidobacterium infantis 35624 – a demonstrated probiotic for IBS
  12. CFS Remission - Bifidobacteriun Infantis – another interesting probiotic
  13. CFS Remission - Lactobacillus Rhamnosis: One of the good ones...
  14. CFS Remission - Bifido|Maximus Histamine-Free and D-Lactate Free Probiotic – Review
  15. CFS Remission - Enterogermina – Four Bacillus clausii strains
  16. CFS Remission - Bioflorin – Enterococcus faecium SF 68
  17. CFS Remission - Lactobacillus Reuteri and recommendations on how to take it
  18. CFS Remission - Lactobacillus Reuteri for B12 production
  19. CFS Remission - GeneralBiotics probiotics
  20. 20.0 20.1 CFS Remission - Should CFS Patients use Lactobacillus Acidophilus? - Probably not
  21. CFS Remission - Megasporebiotic – Preliminary Review
  22. CFS Remission - GcMAF – Bravo Probiotic – a review
  23. CFS Remission - Bifidobacteria probiotics – best bang for the buck!
  24. CFS Remission - Commercial Bifidobacteria probiotics
  25. Groeger, David; O'Mahony, Liam; Murphy, Eileen F.; Bourke, John F.; Dinan, Timothy G.; Kiely, Barry; Shanahan, Fergus; Quigley, Eamonn M. M. (August 2013), "Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut", Gut Microbes, 4 (4): 325–339, ISSN 1949-0984, PMC 3744517Freely accessible, PMID 23842110, doi:10.4161/gmic.25487 
  26. Reference needed

The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history