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=== Tethered cord syndrome === {{Main article|page_name=Tethered cord syndrome}}Tethered cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column. It can be congenital or acquired and appear in childhood or adulthood. It is considered progressive.<ref>{{Cite web|url=https://www.ninds.nih.gov/Disorders/All-Disorders/Tethered-Spinal-Cord-Syndrome-Information-Page | title = Tethered Spinal Cord Syndrome Information Page {{!}} National Institute of Neurological Disorders and Stroke|website=[[National Institute of Neurological Disorders and Stroke]]|access-date=2019-07-26}}</ref> Β It causes spinal cord hypoperfusion, electrophysical changes and metabolic changes, including impaired glucose metabolism.<ref name="Colohan2007">{{Cite journal | last =Colohan | first=Austin R. T. | last2 = Zouros | first2=Alexander | last3=Siddiqi | first3 = Javed | last4 = Yamada | first4 = Shoko M. | last5 = Yamada | first5 = Brian S. | last6 = Pezeshkpour | first6 = Gholam | last7 = Won | first7 = Daniel J. | last8 = Yamada | first8 = Shokei | date = 2007-08-01 | title = Pathophysiology of tethered cord syndrome and similar complex disorders|url=https://thejns.org/view/journals/neurosurg-focus/23/2/foc-07_08_e6.xml|journal=Neurosurgical Focus|language=en-US|volume=23|issue=2|pages=1β10|doi=10.3171/FOC-07/08/E6|issn=1092-0684}}</ref><ref name=Colohan2009>{{Cite journal | last =Colohan | first=Austin R. T. | last2 = Yamada | first2 = Shokei | date = 2009-01-01 | title = Tethered Cord Syndrome|url=https://thejns.org/view/journals/j-neurosurg-spine/10/1/article-p79.xml|journal=Journal of Neurosurgery: Spine|language=en-US|volume=10|issue=1|pages=79β80|doi=10.3171/2008.10.SPI15714L}}</ref><ref name=Sullivan2010>{{Cite journal | last =Sullivan | first = Stephen | last2 = Park | first2 = Paul | last3 = Stetler | first3=William R. | date = 2010-07-01 | title = Pathophysiology of adult tethered cord syndrome: review of the literature|url=https://thejns.org/view/journals/neurosurg-focus/29/1/2010.3.focus1080.xml|journal=Neurosurgical Focus|language=en-US|volume=29|issue=1| pages = E2|doi=10.3171/2010.3.FOCUS1080|issn=1092-0684}}</ref> As with [[craniocervical instability]], There have also been anecdotal reports of patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) who were later diagnosed with tethered cord, although no scientific publication on this subject exists.<ref name=":0" /><ref name=":1" /><ref name=":4" />Β
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