Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Myalgic encephalomyelitis/he
(section)
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==Signs and symptoms== Myalgic encephalomyelitis is a [[neurological disorder|neurological disease]] that affects multiple bodily systems, causing a widespread combination of symptoms.<ref name="ICC" /> Symptoms can range from mild to very severe and can include: <div style="column-count:2;"> * [[ataxia|ataxia (coordination difficulties)]] * [[cognitive dysfunction]] * [[Chronic fatigue|fatigability]] * [[gastrointestinal]] symptoms * [[headache]] *[[low-grade fever]], [[Temperature dysregulation|temperature instability]] *[[muscle]] [[Muscle weakness|weakness]] and [[Muscle fatigability|fatiguability]] *[[myalgia|myalgia (muscle pain)]] *neck and back or [[spinal cord]] stiffness *[[neuralgia|neuralgia (nerve pain)]] *[[Orthostatic intolerance|othostatic intolerance]] *[[post-exertional malaise]] *sensitivity to [[Temperature sensitivity|heat or cold]] *sensitivity to [[Light sensitivity|light]], [[Hyperacusis|sound]] and/or [[Allodynia|touch]] *[[sleep dysfunction]]<ref name="ICC">{{Cite journal | last = Carruthers | first = Bruce M. | authorlink = Bruce Carruthers | last2 = van de Sande | first2 = Marjorie I. | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = Kenny L. | authorlink3=Kenny De Meirleir | last4 = Klimas | first4 = Nancy G. | author-link4 = Nancy Klimas | last5 = Broderick | first5 = Gordon | author-link5 = Gordon Broderick | last6 = Mitchell | first6 = Terry | authorlink6 = Terry Mitchell | last7 = Staines | first7 = Donald | author-link7 = Donald Staines | last8 = Powles | first8 = A.C. Peter | authorlink8 = A C Peter Powles | last9 = Speight | first9 = Nigel | authorlink9 = Nigel Speight | last10 = Vallings | first10 = Rosamund | authorlink10 = Rosamund Vallings | last11 = Bateman | first11 = Lucinda | authorlink11 = Lucinda Bateman | last12 = Baumgarten-Austrheim | first12 = Barbara | authorlink12 = Barbara Baumgarten-Austrheim | last13 = Bell | first13 = David | author-link13 = David Bell | last14 = Carlo-Stella | first14 = Nicoletta | author-link14 = Nicoletta Carlo-Stella | last15 = Chia | first15 = John | author-link15 = John Chia | last16 = Darragh | first16 = Austin | author-link16 = Austin Darragh | last17 = Jo | first17 = Daehyun | author-link17 = Daehyun Jo | last18 = Lewis | first18 = Donald | author-link18 = Donald Lewis | last19 = Light | first19 = Alan | author-link19 = Alan Light | last20 = Marshall-Gradisnik | first20 = Sonya | author-link20 = Sonya Marshall-Gradisnik | last21 = Mena | first21 = Ismael | author-link21 = Ismael Mena | last22 = Mikovits | first22 = Judy | author-link22 = Judy Mikovits | last23 = Miwa | first23 = Kunihisa | author-link23 = Kunihisa Miwa | last24 = Murovska | first24 = Modra | author-link24 = Modra Murovska | last25 = Pall | first25 = Martin | author-link25 = Martin Pall | last26 = Stevens | first26 = Staci | author-link26 = Staci Stevens | date = 2011-08-22 | title=Myalgic encephalomyelitis: International Consensus Criteria|url=https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2796.2011.02428.x|journal=Journal of Internal Medicine|language=en|volume=270|issue=4|pages=327–338|doi=10.1111/j.1365-2796.2011.02428.x|issn=0954-6820|pmc=3427890|pmid=21777306|via=}}</ref> </div> [[File:ME CFS.png|alt=Myalgic encephalomyelitis is an acquired neurological disease with complex global dysfunctions. Pathological dysregulation of the nervous, immune and endocrine systems, with impaired cellular energy metabolism and ion transport are prominent features. - International Consensus Criteria|thumb|upright=1.6|left]] Symptom presentation and severity can vary considerably day to day and even hour to hour.<ref name="NORD" /> Overexertion can exacerbate all symptoms, and post-exertional malaise often delayed by 24 hours or more.<ref>{{Cite web|url=http://www.investinme.org/landerP5.shtml | title = Invest in ME Research - Invest in ME Research Home Page | last = Research | first = | authorlink = Invest in ME Research|website=[[Invest in ME Research]]|access-date=2018-09-08}}</ref><ref name="NORD" /> The US [[National Institutes of Health]] (NIH) notes that sensitivity to noise, light and [[multiple chemical sensitivity|chemical]]s may force patients to withdraw from society.<ref>{{Cite news | url=https://prevention.nih.gov/programs-events/pathways-to-prevention/workshops/me-cfs | title = Pathways to Prevention (P2P) Advancing the Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | last = | first = | date = |work=Office of Disease Prevention|access-date=2018-09-08|archive-url=|archive-date=|url-status=|language=en}}</ref> === Post-exertional malaise === {{Main article | page_name =Post-exertional malaise}} A core symptom, [[post-exertional malaise]] (PEM), is intolerance to previously trivial mental or physical effort such as attending a child's school event, running an errand or grocery shopping, taking a shower or brushing teeth; this causes a worsening of symptoms, and deterioration of health from persistent or repeated exertion.<ref name="P2P" /><ref name="ICC2011primer" /><ref name="CDC-symptoms" /> [[File:J Brea TED.JPG|200px|thumb|right|[[Jen Brea|Jennifer Brea]] is an American who was studying at Harvard; while on a trip to [[Kenya]] she became very ill with what would eventually be diagnosed as [[ME/CFS]]. Brea began experiencing [[Nervous system|neurological]] problems. Her neurologist diagnosed her with "conversion disorder" ([[hysteria]]). When walking home from his office, she collapsed. [[Severe and very severe ME|Jen then needed to use a wheelchair]] to keep her legs up due to [[Postural orthostatic tachycardia syndrome|POTS]] as her blood pools into her legs. View her TED Talk ''[https://www.ted.com/talks/jen_brea_what_happens_when_you_have_a_disease_doctors_can_t_diagnose What happens when you have a disease doctors can't diagnose]'']] The severity of a patient's symptoms often depends on the time period since the disease was contacted and rate of progression of each patient. The rate of progression can be accelerated by ''physical or cognitive activity'' beyond a patient's limits over long periods, which typically entails [[anaerobic]] activity.{{Citation needed | date = February 2021}}
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
This page is a member of 3 hidden categories:
Category:All articles with unsourced statements
Category:Articles with unsourced statements from 2021
Category:Pages with reference errors
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs