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Myalgic encephalomyelitis/he
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==Epidemiology == {{Main article |page_name = Epidemiology of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome}} ME has been found world-wide, in at least 75 [[Outbreaks|epidemics]] documented in published papers from the 1930s to the 1980s.<ref>{{Cite web|url=http://www.hfme.org/methemedicalfacts.htm | title = M.E.: The medical facts | last = Bassett | first = Jodi | date = Sep 2010 | website = The Hummingbirds' Foundation for M.E.|archive-url=|archive-date=|url-status=|access-date=2018-09-08}}</ref> Epidemics often occur in enclosed communities such as schools and hospitals. As observed in many autoimmune disorders, ME is more common in females than males; the mean sex ratio is approximately 2-3 females for every male.<ref>{{Cite journal | last = Bakken | first = Inger Johanne | last2 = Tveito | first2 = Kari | last3 = Gunnes | first3 = Nina | last4 = Ghaderi | first4 = Sara | last5 = Stoltenberg | first5 = Camilla | last6 = Trogstad | first6 = Lill | last7 = H åberg | first7 = Siri Eldevik | last8 = Magnus | first8 = Per | date = 2014-10-01 | title = Two age peaks in the incidence of chronic fatigue syndrome/myalgic encephalomyelitis: a population-based registry study from Norway 2008-2012|url=http://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-014-0167-5|journal=BMC Medicine|language=en|volume=12|issue=1|pages=|doi=10.1186/s12916-014-0167-5|issn=1741-7015|pmid=25274261|via=}}</ref> In children the sex ratio is approximately equal.<ref>{{Cite journal | last = Collin | first = Simon M. | last2 = Nuevo | first2 = Roberto | last3 = van de Putte | first3 = Elise M. | last4 = Nijhof | first4 = Sanne L. | last5 = Crawley | first5 = Esther | date = 2015-10-28 | title = Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME) is different in children compared to in adults: a study of UK and Dutch clinical cohorts|url=https://www.ncbi.nlm.nih.gov/pubmed/26510728|journal=BMJ open|volume=5|issue=10| pages = e008830|doi=10.1136/bmjopen-2015-008830|issn=2044-6055|pmid=26510728|via=}}</ref>
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