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Fludrocortisone
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== Use in chronic fatigue syndrome == <nowiki>*</nowiki>In 1998, a study by Phillip K. Peterson, et al, showed that low-dose fludrocortisone does not provide sufficient benefit to patients with chronic fatigue syndrome. Using the [[Short Form 36-Item Health Survey|36-Item Short-Form Health Survey]], a reaction time test, and a treadmill exercise test, they found no observed improvement in the severity of any symptom. Likewise, blood pressure and heart rate readings were unaffected by treatment.<ref name=":0">{{Cite journal | last = Peterson | first = Phillip K. | last2 = Pheley | first2 = Alfred | last3 = Schroeppel | first3 = Jill | last4 = Schenck | first4 = Carlos | last5 = Marshall | first5 = Paul | last6 = Kind | first6 = Allan | last7 = Haugland | first7 = J. Mark | last8 = Lambrecht | first8 = Lawrence J. | last9 = Swan | first9 = Suzanne | date = 27 Apr 1998 | title = A Preliminary Placebo-Controlled Crossover Trial of Fludrocortisone for Chronic Fatigue Syndrome | url =http://archinte.jamanetwork.com/article.aspx?doi=10.1001/archinte.158.8.908|journal=Archives of Internal Medicine|language=en|volume=158|issue=8 | pages = 908|doi=10.1001/archinte.158.8.908|issn=0003-9926|via=}}</ref> [[ME/CFS]] patients often have OI or POTS and these conditions could improve by taking fludrocortisone.<ref>{{Cite web | url = http://www.nationalacademies.org/hmd/~/media/Files/Report%20Files/2015/MECFS/MECFS_ProposedDiagnosticCriteria | title = Proposed Diagnostic Criteria for ME/CFS | last = | first = | date = 2015 | website = nationalacademiesofmedicine.org|archive-url=|archive-date=|url-status=|access-date=}}</ref><ref>{{Cite journal | last = Wright Clayton | first = Ellen | last2 = Algeria | first2 = Margarita | last3 = Bateman | first3 = Lucinda | last4 = Chu | first4 = Lily | last5 = Cleeland | first5 = Charles | last6 = Davis | first6 = Ronald | last7 = Diamond | first7 = Betty | last8 = Ganiats | first8 = Theodore | last9 = Keller | first9 = Betsy | date = 2015-03-16|others=Nancy Klimas; A Martin Lerner; Cynthia Murlow; Benjamin Natelson; Peter Rowe; Michale Shelanski | title = Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | url =https://www.nap.edu/read/19012/chapter/6#107|journal=National Academy of Medicine Education|language=en|volume= | pages = 107-119|doi=10.17226/19012|via=NAP.EDU}}</ref>
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