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Cara Tomas
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[[File:Cara Tomas.png|200px|thumb|right]] '''Cara Tomas''', PhD, is a Postdoctoral Research Associate at the [http://www.ncl.ac.uk/icm/research/ Institute of Cellular Medicine], Newcastle University, Newcastle upon Tyne, [[United Kingdom|UK]]. Tomas' interest in [[ME/CFS]] stems from her own experience with acute onset ME/CFS leaving her bedbound for a time.<ref name=":0">{{Cite journal | last = Streeten | first = David H.P. | last2 = Bell | first2 = David S. | date = Jan 1998 | title = Circulating Blood Volume in Chronic Fatigue Syndrome | url =http://dx.doi.org/10.1300/j092v04n01_02 | journal = Journal of Chronic Fatigue Syndrome | volume = 4 | issue = 1 | pages = 3β11|doi=10.1300/j092v04n01_02|issn=1057-3321}}</ref> ==Notable studies== *2017, Cellular [[bioenergetics]] is impaired in patients with chronic fatigue syndrome<ref>{{Cite journal | last = Tomas | first = Cara | author-link = Cara Tomas | last2 = Brown | first2 = Audrey | author-link2 = Audrey Brown | last3 = Strassheim | first3 = Victoria | author-link3 = Victoria Strassheim | last4 = Elson | first4 = Joanna | last5 = Newton | first5 = Julia | author-link5 = Julia Newton | last6 = Manning | first6 = Philip | date = Oct 24, 2017 | title = Cellular bioenergetics is impaired in patients with chronic fatigue syndrome | url =http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186802 | journal = PLOS ONE|language=en | volume = 12 | issue = 10| pages = e0186802|doi=10.1371/journal.pone.0186802|issn=1932-6203|pmc=|pmid=29065167|via=}}</ref> - [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186802 (Full Text)] *2017, Elevated brain natriuretic peptide levels in chronic fatigue syndrome associate with [[Cardiac problems in ME/CFS|cardiac dysfunction]]: a case control study<ref name="Tomas, 2017" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761285/ (Full Text)] *2018, [[Metabolic]] abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review<ref name="Tomas, 2018" /> - [https://www.ncbi.nlm.nih.gov/pubmed/29666214 (Abstract)] * 2018, A new approach to find [[Diagnostic biomarker|biomarkers]] in [[ME/CFS|chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)]] by single-cell Raman micro-spectroscopy<ref>{{Cite journal | last = Xu | first = Jiabao | last2 = Potter | first2 = Michelle | last3 = Tomas | first3 = Cara | author-link3 = Cara Tomas | last4 = Elson | first4 = Jo | last5 = Morten | first5 = Karl | author-link5 = Karl Morten | last6 = Poulton | first6 = Joanna | last7 = Wang | first7 = Ning | last8 = Jin | first8 = Hanqing | last9 = Hou | first9 = Zhaoxu | date = 2018 | title = A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy | url = https://pubs.rsc.org/en/content/articlelanding/2018/an/c8an01437j/unauth#!divRelatedContent&articles | journal = The Analyst|language=en | volume = | pages=|doi=10.1039/C8AN01437J|issn=0003-2654|via=}}</ref> - [https://pubs.rsc.org/en/content/articlelanding/2018/an/c8an01437j/unauth#!divRelatedContent&articles (Abstract)] *2019, [[Mitochondrial DNA|MtDNA]] population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: A study of mildly deleterious variants<ref>{{Cite journal | last = Venter | first = Marianne | author-link = | last2 = Tomas | first2 = Cara | author-link2 = Cara Tomas | last3 = Pienaar | first3 = Ilse S. | author-link3 = | last4 = Strassheim | first4 = Victoria | author-link4 = Victoria Strassheim | last5 = Erasmus | first5 = Elardus | author-link5 = | last6 = Ng | first6 = Wan-Fai | author-link6 = | last7 = Howell | first7 = Neil | last8 = Newton | first8 = Julia L. | author-link8 = Julia Newton | last9 = Van der Westhuizen | first9 = Francois H. | date = Dec 2019 | title = MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: a study of mildly deleterious variants |url =http://www.nature.com/articles/s41598-019-39060-1 | journal = Scientific Reports|language=en | volume = 9 | issue = 1| pages=|doi=10.1038/s41598-019-39060-1|issn=2045-2322|pmc=|pmid=30814539|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393470/ (Full text)] *2019, The role of mitochondria in ME/CFS: a perspective<ref>{{Cite journal | last = Tomas | first = Cara | author-link = Cara Tomas | last2 = Elson | first2 = Joanna L | date = 2019-02-26 | title = The role of mitochondria in ME/CFS: a perspective | url =https://www.tandfonline.com/doi/full/10.1080/21641846.2019.1580855|journal = Fatigue: Biomedicine, Health & Behavior |language=en | volume = | issue = | pages = 1β7|doi=10.1080/21641846.2019.1580855|issn=2164-1846|quote=|via=}}</ref> - [https://www.tandfonline.com/doi/abs/10.1080/21641846.2019.1580855?journalCode=rftg20 (Abstract)] *2019, [[mitochondrion|Mitochondrial]] complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types<ref>{{Cite journal | last = Tomas | first = Cara | author-link = Cara Tomas | last2 = Brown | first2 = Audrey E. | author-link2 = Audrey Brown | last3 = Newton | first3 = Julia L. | author-link3 = Julia Newton | last4 = Elson | first4 = Joanna L. | author-link4 = | author-link5 = | date = 2019-03-01 | title = Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types |url =https://peerj.com/articles/6500 | journal = PeerJ|language=en | volume = 7 | issue = | pages = e6500|doi=10.7717/peerj.6500|issn=2167-8359|pmc=|pmid=30847260|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398432/ (Full text)] * 2019, Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test<ref name="Morten2019">{{Cite journal | last = Morten | first = Karl J. | author-link = Karl Morten | last2 = Newton | first2 = Julia L. | author-link2 = Julia Newton | first3 = Joanna L. | last3 = Elson | author-link3 = Joanna Elson | last4 = Potter | first4 = Michelle | author-link4 = Michelle Potter | last5 = Lodge | first5 = Tiffany A. | author-link5 = Tiffany Lodge | last6 = Tomas | first6 = Cara | author-link6 = Cara Tomas | date = 2019-08-07 | title = Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test | url = https://www.nature.com/articles/s41598-019-47966-z | journal = Scientific Reports|language=en | volume = 9 | issue = 1 | pages = 1β9|doi=10.1038/s41598-019-47966-z|issn=2045-2322|quote=|via=}}</ref> - [https://www.nature.com/articles/s41598-019-47966-z (Full text)] *2020, The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function<ref name="Tomas2020">{{Cite journal | last = Tomas | first = Cara | author-link = Cara Tomas | first2 = Joanna L. | last2 = Elson | author-link2 = Joanna Elson | last3 = Newton | first3 = Julia L. | author-link3 = Julia Newton | last4 = Strassheim | first4 = Victoria | author-link4 = Victoria Strassheim | last5 = Walker | first5 = Mark | author-link5 = Mark Walker | date = 2020-04-10 | title = The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function | url =https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231136 | journal = PLoS ONE |language=en | volume = 15 | issue = 4| pages = e0231136|doi=10.1371/journal.pone.0231136|issn=|quote=|via=}}</ref> - [https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231136 (Full text)] *2020, Substrate utilisation of cultured skeletal muscle cells in patients with CFS<ref>{{Cite journal | last = Tomas | first = Cara | author-link = Cara Tomas | last2 = Elson | first2 = Joanna L. | author-link2 = | last3 = Newton | first3 = Julia L. | author-link3 = Julia Newton | last4 = Walker | first4 = Mark | author-link4 = | date = Dec 2020 | title = Substrate utilisation of cultured skeletal muscle cells in patients with CFS | url = http://www.nature.com/articles/s41598-020-75406-w | journal = Scientific Reports|language=en | volume = 10 | issue = 1 | pages = 18232|doi=10.1038/s41598-020-75406-w|issn=2045-2322|pmc = 7588462|pmid=33106563|access-date=|quote=|via=}}</ref> - [https://www.nature.com/articles/s41598-020-75406-w (Full text)] ==Talks and interviews== * 4 May 2018 -Speaker at [[ME/CFS Canadian Collaborative Team Conference]] - ''Cellular Bioenergetics is Impaired in Patients with ME/CFS''<ref>{{Cite web | url = https://fourwaves-sots.s3.amazonaws.com/static/media/uploads/5FFGG5h0kBRlJTgexdugaQ%3D%3D/2018/04/24/me_cfs_final-program.pdf | title=ME/CFS Canadian Collaborative Team Conference | last = | first = | author-link = | date = | website = | archive-url = | archive-date = |url-status = | access-date=2019-03-11}}</ref> * 20 Sep 2018 - Speaker at [[CFS/ME Research Collaborative Conference|UK CFS/ME Research Collaborative Conference]]; Title - ''[https://www.youtube.com/watch?v=cqw0q38eDss Cellular bioenergetics in ME/CFS]''<ref>{{Cite web | url = https://www.actionforme.org.uk/uploads/images/2018/09/cmrc-2018-programme-final-revision.pdf | title=UK CFS/ME Research Collaborative Conference programme | last = | first = | author-link = | date = | website = Action for ME| archive-url = | archive-date = |url-status = | access-date=2019-03-05}}</ref> ==Online presence== *[https://www.linkedin.com/in/cara-tomas-5031668a/ LinkedIn] ==See also== *[[Mitochondrion]] ==Learn more== *[https://www.meassociation.org.uk/2017/11/we-hear-from-cara-tomas-about-her-recent-study-on-cellular-bioenergetic-deficiencies-in-mecfs-13-november-2017/ We hear from Cara Tomas about her recent study on cellular bioenergetic deficiencies in ME/CFS | 13 November 2017] by the [[ME Association]] *[https://www.newscientist.com/article/2152357-blood-cells-in-chronic-fatigue-syndrome-are-drained-of-energy/ Blood cells in chronic fatigue syndrome are drained of energy]<ref name=":0" /> by Andy Coghlan for New Scientist ==References== <references> <ref name="Tomas, 2017">{{Citation | last1 = Tomas | first1 = Cara| author-link1 = Cara Tomas | last2 = Finkelmeyer | first2 = Andreas | author-link2 = Andreas Finkelmeyer | last3 = Hodgson | first3 = Tim| author-link3 = | last4 = MacLachlan | first4 = Laura | author-link4 = | last5 = MacGowan | first5 = Guy A | author-link5 = | last6 = Blamire | first6 = Andrew M | author-link6 = | last7 = Newton | first7 = Julia L | author-link8 = Julia Newton | title = Elevated brain natriuretic peptide levels in chronic fatigue syndrome associate with cardiac dysfunction: a case control study | journal =Open Heart | volume = | issue = | page = | date = 2017 | pmid = | doi = 10.1136/openhrt-2017-000697 | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761285/ }}</ref> <ref name="Tomas, 2018">{{Citation | last1 = Tomas | first1 = Cara| author-link1 = Cara Tomas | last2 = Newton | first2 = Julia L | author-link2 = Julia Newton | title = Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review | journal = Biochemical Society Transactions | volume = | issue = | page = | date = 2018 | pmid = 29666214 | doi = 10.1042/BST20170503 }}</ref> </references> [[Category:Researchers]] [[Category:UK researchers]] [[Category:People with ME, CFS, and/or FMS]]
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