M. Ronald Glaser, Ph.D, is a professor in the Department of Cancer Biology and Genetics and Director of the Institute for Behavioral Medicine Research at the College of Medicine, The Ohio State University, Columbus, Ohio. His main research interests are tumor virology/stress and immunology.
Dr. Glaser advocates that a possible subset of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) could be from viral reactivation following a stressful event. In 2012, Dr Glaser and his team announced work on a possible diagnostic biomarker for CFS that involves the detection of EBV-encoded DNA polymerase and EBV-encoded dUTPase, two proteins that are produced early in the process of Epstein-Barr virus reactivation.
Chronic Fatigue Syndrome Advisory Committee[edit | edit source]
2001 CDC Case Definition Workshop[edit | edit source]
In 2001, the CDC held a three-day workshop on Issues Related to the Chronic Fatigue Syndrome (CFS) Research Case Definition. Dr Glaser was one of the invited participants. During the workshop, Dr Glaser gave the presentation: "Immune Modulation by Latent Herpesvirus Proteins."
Notable studies[edit | edit source]
- 2012, Antibody to Epstein-Barr Virus Deoxyuridine Triphosphate Nucleotidohydrolase and Deoxyribonucleotide Polymerase in a Chronic Fatigue Syndrome Subset (Full Text)
- 2005, Stress-associated changes in the steady state expression of latent Epstein-Barr Virus: Implications for Chronic Fatigue Syndrome and Cancer
- 1998, Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome.
- 1986, Stress depresses interferon production by leukocytes concomitant with a decrease in natural killer cell activity.
Talks & interviews[edit | edit source]
Online presence[edit | edit source]
Learn more[edit | edit source]
- 2013, "Dr. Ronald Glaser - Chronic Fatigue Syndrome and the Pathophysiology of EBV Infection " by Cort Johnson
See also[edit | edit source]
References[edit | edit source]
- HHS.gov (2009), May 27 & 28, 2009 CFSAC Meeting (PDF) (Roster)
- HHS.gov (2010), October 12 & 13, 2010 CFSAC Meeting (PDF) (Roster)
- Lerner, AM; Ariza, ME; Williams, M; Jason, L; Beqaj, S; Fitzgerald, JT; Lemeshow, S; Glaser, R (2012), "Antibody to Epstein-Barr Virus Deoxyuridine Triphosphate Nucleotidohydrolase and Deoxyribonucleotide Polymerase in a Chronic Fatigue Syndrome Subset", PLoS ONE, 7 (11): e47891, doi:10.1371/journal.pone.0047891
- Glaser, R.; Padgett, D.A.; Litsky, M.L.; Baiocchi, R.A.; Yang, E.V.; Chen, M.; Yeh, P-E.; Klimas, N.G.; Marshall, G.D.; Whiteside, T.; Herberman, R.; Kiecolt-Glaser, J.K.; Williams, M.V. (2005), "Stress-associated changes in the steady state expression of latent Epstein-Barr Virus: Implications for Chronic Fatigue Syndrome and Cancer", Brain, Behavior and Immunity, 19 (2): 91-103, doi:10.1016/j.bbi.2004.09.001, PMID 15664781
- Glaser, R; Kiecolt-Glaser, JK (1998), "Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome.", The American Journal of Medicine, 105(3A): 35S-42S, PMID 9790480
- Glaser, Ronald; Rice, John; Speicher, Carl E.; Stout, Julie C.; Kiecolt-Glaser, Janice K. (Oct 1986), "Stress depresses interferon production by leukocytes concomitant with a decrease in natural killer cell activity.", Behavioral Neuroscience, 100(5): 675-678, doi:10.1037/0735-7044.100.5.675