Cocoa

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Cocoa (in the form of dark chocolate) may improve the symptoms of Chronic Fatigue Syndrome.[1]

In animal models, cocoa may inhibit the function of type 2 T helper cells,[2][3][4] increase intestinal T lymphocyte count, [3] and decrease secretory IgA.[5]

Cocoa was also found to significantly increase Lactobacillus casei in pigs.[4]

Chocolate contains phenylalanine, a dopamine precursor.

Mendus is running a small unblinded trial to assess cocoa in ME/CFS.[6]

Prebiotic[edit]

Some evidence suggests dark chocolate may provide benefits to the gut microbiome.[7]

Learn more[edit]

See also[edit]

References[edit]

  1. Sathyapalan, Thozhukat; Beckett, Stephen; Rigby, Alan S.; Mellor, Duane D.; Atkin, Stephen L. (2010), "High cocoa polyphenol rich chocolate may reduce the burden of the symptoms in chronic fatigue syndrome", Nutrition Journal, 9: 55, ISSN 1475-2891, doi:10.1186/1475-2891-9-55, retrieved 2016-11-09 
  2. Pérez-Cano, Francisco J.; Massot-Cladera, Malen; Franch, Àngels; Castellote, Cristina; Castell, Margarida (2013-06-04), "The effects of cocoa on the immune system", Frontiers in Pharmacology, 4, ISSN 1663-9812, PMC 3671179free to read, PMID 23759861, doi:10.3389/fphar.2013.00071, retrieved 2016-11-09 
  3. 3.0 3.1 Pérez-Cano, Francisco J.; Massot-Cladera, Malen; Franch, Àngels; Castellote, Cristina; Castell, Margarida (2013-06-04), "The effects of cocoa on the immune system", Frontiers in Pharmacology, 4, ISSN 1663-9812, PMC 3671179free to read, PMID 23759861, doi:10.3389/fphar.2013.00071, retrieved 2016-11-09 
  4. 4.0 4.1 Jang, Saebyeol; Sun, Jianghao; Chen, Pei; Lakshman, Sukla; Molokin, Aleksey; Harnly, James; Joseph Urban, Jr; Davis, Cindy; Solano-Aguilar, Gloria (2015-04-01), "Changes in the Intestinal Microbiota and Host Inflammatory Gene Expression in Pigs Fed a Flavanol-Enriched Cocoa Powder", The FASEB Journal, 29 (1 Supplement): 914–4, ISSN 0892-6638, retrieved 2016-11-09 
  5. Ramiro-Puig, Emma; Pérez-Cano, Francisco J.; Ramos-Romero, Sara; Pérez-Berezo, Teresa; Castellote, Cristina; Permanyer, Joan; Franch, Àngels; Izquierdo-Pulido, Maria; Castell, Margarida (August 2008), "Intestinal immune system of young rats influenced by cocoa-enriched diet", The Journal of Nutritional Biochemistry, 19 (8): 555–565, ISSN 0955-2863, doi:10.1016/j.jnutbio.2007.07.002, retrieved 2016-11-09 
  6. The ME/CFS Dark Chocolate Study
  7. Bifidobacterium, Chocolate and CFS


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history