GABA: Difference between revisions
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'''Gamma aminobutyric acid''' (GABA), is a [[neurotransmitter]] made from the [[:Category:Amino acids|amino acid]] [[glutamate]]. GABA is the chief inhibiting, or calming [[neurotransmitter]] in the [[brain]], functioning as a brake on the neural circuitry during [[stress]]. Low GABA levels are associated with [[restlessness]], [[anxiety]], [[insomnia]] and a | '''Gamma aminobutyric acid''' (GABA), is a [[neurotransmitter]] made from the [[:Category:Amino acids|amino acid]] [[glutamate]]. GABA is the chief inhibiting, or calming [[neurotransmitter]] in the [[brain]], functioning as a brake on the neural circuitry during [[stress]]. Low GABA levels are associated with [[restlessness]], [[anxiety]], [[insomnia]] and a low mood/[[depression]]. GABA works to balance [[glutamate]] (excitatory) in the brain. GABA is the brake pedal on a car while glutamate is the gas pedal.{{citation needed}} | ||
Supplements to support GABA | Supplements to support GABA and glutamate are: | ||
amino acids GABA | *amino acids GABA | ||
*[[theanine|L-theanine]] | |||
*[[N-acetyl-cysteine]] (NAC) | |||
*[[vitamin B6]] | |||
*[[vitamin D]] | |||
*[[magnesium]] | |||
*[[zinc]] | |||
*[[Omega 3 fatty acid]], and | |||
*[[inositol]]{{citation needed|date=September 2020}} | |||
==Notable studies== | ==Notable studies== | ||
*2005, [https://www.ncbi.nlm.nih.gov/pubmed/15757488 GABA and glutamate systems as therapeutic targets in depression and mood disorders] | *2005, [https://www.ncbi.nlm.nih.gov/pubmed/15757488 GABA and glutamate systems as therapeutic targets in depression and mood disorders] | ||
*2005, [https://www.ncbi.nlm.nih.gov/pubmed/16400244 Beyond monoamines: glutamatergic function in mood disorders] | *2005, [https://www.ncbi.nlm.nih.gov/pubmed/16400244 Beyond monoamines: glutamatergic function in mood disorders] | ||
*2006, [https://www.ncbi.nlm.nih.gov/pubmed/16971751 Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans] | *2006, [https://www.ncbi.nlm.nih.gov/pubmed/16971751 Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans]<ref name=pmid16971751>{{PMID|16971751}}</ref> | ||
*2007, Thorne Research, Inc: Gamma-Aminobutyric Acid (GABA). Alternative Medicine Review, 2007; 12(3) | *2007, Thorne Research, Inc: Gamma-Aminobutyric Acid (GABA). Alternative Medicine Review, 2007; 12(3) | ||
==See also== | ==See also== | ||
*[[:Category:Neurotransmitters]] | *[[Glutamate]] | ||
*[[:Category:Neurotransmitters|Neurotransmitters (category)]] | |||
==Learn more == | ==Learn more == | ||
Revision as of 00:15, September 28, 2020
 | This article needs cleanup to meet MEpedia's guidelines. The reason given is: This page needs additional references or sources for verification - multiple references need to be added. (Dec 2019) |
Gamma aminobutyric acid (GABA), is a neurotransmitter made from the amino acid glutamate. GABA is the chief inhibiting, or calming neurotransmitter in the brain, functioning as a brake on the neural circuitry during stress. Low GABA levels are associated with restlessness, anxiety, insomnia and a low mood/depression. GABA works to balance glutamate (excitatory) in the brain. GABA is the brake pedal on a car while glutamate is the gas pedal.[citation needed]
Supplements to support GABA and glutamate are:
- amino acids GABA
- L-theanine
- N-acetyl-cysteine (NAC)
- vitamin B6
- vitamin D
- magnesium
- zinc
- Omega 3 fatty acid, and
- inositol[citation needed]
Notable studies
- 2005, GABA and glutamate systems as therapeutic targets in depression and mood disorders
- 2005, Beyond monoamines: glutamatergic function in mood disorders
- 2006, Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans[1]
- 2007, Thorne Research, Inc: Gamma-Aminobutyric Acid (GABA). Alternative Medicine Review, 2007; 12(3)
