Gut-brain axis

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The gut-brain axis is the bidirectional biochemical signaling that takes places between the gut and the brain, often involving intestinal microbiota. It is a framework that explains how dysbiosis might effect brain function in neurological disease and how attempt to alter micro biome composition might be therapeutic.

Most scientific knowledge about gut-brain interactions comes from the study of germ-free and single organism mice, that is mice that are raised with a completely sterile gastrointestinal tract or who are inoculated with a single bacterial species. Mice that develop without a microbiome have sensory processing impairments and impairments of the hypothalamic-pituitary-adrenal axis stress response.


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history