Alison Wearden

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Alison J. Wearden is a psychologist and professor of Health Psychology at the University of Manchester, Manchester, UK. Professor Wearden, who has a particular interest in chronic fatigue syndrome, did her MSc on cognitive dysfunction in chronic fatigue syndrome. She is also a former co-editor of the Journal of Health Psychology.[1]

Wearden was the Principal Investigator of the 2006 and 2010 FINE trial (Fatigue Intervention by Nurses Evaluation trial), a study to evaluate the effectiveness of home delivered rehabilitation and supportive listening for patients in primary care with chronic fatigue syndrome/myalgic encephalomyelitis or encephalitis (CFS/ME).[2]

Notable studies[edit | edit source]

  • 1996, Research on cognitive complaints and cognitive functioning in patients with chronic fatigue syndrome (CFS): What conclusions can we draw?[3]
  • 1997, The relation of sleep difficulties to fatigue, mood and disability in chronic fatigue syndrome[4] - (Abstract)
  • 1997, Cognitive performance and complaints of cognitive impairment in chronic fatigue syndrome (CFS)[5]
  • 1998, A comparison of salivary cortisol in chronic fatigue syndrome, community depression and healthy controls[6]
  • 1998, Screening instruments for psychiatric morbidity in chronic fatigue syndrome[7] - (Full text)
  • 1998, Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome[8]
  • 1999, Prediction of peak oxygen uptake in chronic fatigue syndrome[9] - (Full text)
  • 1999, The role of depression in pain, psychophysiological syndromes and medically unexplained symptoms associated with chronic fatigue syndrome[10]
  • 2001, The Family Response Questionnaire: a new scale to assess the responses of family members to people with chronic fatigue syndrome[11]
  • 2006, Fatigue Intervention by Nurses Evaluation – The FINE Trial. A randomised controlled trial of nurse led self-help treatment for patients in primary care with chronic fatigue syndrome: study protocol[12] - (Full text)
  • 2008, Using multiple sources of knowledge to reach clinical understanding of chronic fatigue syndrome[13] - (Full text)
  • 2010, Nurse led, home based self help treatment for patients in primary care with chronic fatigue syndrome: randomised controlled trial[14] - (Full text)
  • 2010, Making the diagnosis of Chronic Fatigue Syndrome/Myalgic Encephalitis in primary care: a qualitative study[15] - (Full text)
  • 2011, Factors influencing engagement of patients in a novel intervention for CFS/ME: a qualitative study
  • 2011, Challenges of nurse delivery of psychological interventions for long-term conditions in primary care: a qualitative exploration of the case of chronic fatigue syndrome/myalgic encephalitis[16] - (Full text)
  • 2012, Depressive symptoms and pragmatic rehabilitation for chronic fatigue syndrome[17]
  • 2012, Developing resources to support the diagnosis and management of Chronic Fatigue Syndrome/Myalgic Encephalitis (CFS/ME) in primary care: a qualitative study[18] - (Full text)
  • 2013, Cost-effectiveness of supported self-management for CFS/ME patients in primary care[19] - (Full text)
  • 2013, Mediators of the effects on fatigue of pragmatic rehabilitation for chronic fatigue syndrome[20]
  • 2013, Attributions, distress and behavioural responses in the significant others of people with chronic fatigue syndrome[21]
  • 2014, Diagnosis and management of chronic fatigue syndrome/myalgic encephalitis in black and minority ethnic people: a qualitative study[22]
  • 2014, Overcoming the barriers to the diagnosis and management of chronic fatigue syndrome/ME in primary care: a meta synthesis of qualitative studies[23] - (Full text)
  • 2014, Couples' experiences of interacting with outside others in chronic fatigue syndrome: a qualitative study[24]
  • 2014, The impact of significant other expressed emotion on patient outcomes in chronic fatigue syndrome[25] - (Full text)
  • 2015, Understanding medical students' views of chronic fatigue syndrome: a qualitative study[26]
  • 2015, Therapist Effects and the Impact of Early Therapeutic Alliance on Symptomatic Outcome in Chronic Fatigue Syndrome[27] - (Full text)
  • 2015, Patient Outcomes in Association With Significant Other Responses to Chronic Fatigue Syndrome: A Systematic Review of the Literature[28] - (Full text)
  • 2015, Significant other behavioural responses and patient chronic fatigue syndrome symptom fluctuations in the context of daily life: An experience sampling study[29] - (Full text)
  • 2016, Implementing resources to support the diagnosis and management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in primary care: A qualitative study[30] - (Full text)
  • 2016, Distress in significant others of patients with chronic fatigue syndrome: A systematic review of the literature[31]
  • 2017, Do evidence based interventions for chronic fatigue syndrome improve sleep? A systematic review and narrative synthesis[32]
  • 2017, Activity Patterns in Response to Symptoms in Patients Being Treated for Chronic Fatigue Syndrome: An Experience Sampling Methodology Study[33] - (Full text)

Talks and interviews[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

  • Wikipedia
  • University of Manchester

References[edit | edit source]

  1. ↑ "Alison Wearden | Research Explorer | The University of Manchester". University of Manchester. Retrieved October 16, 2018.
  2. ↑ Wearden, A.J.; Dowrick, C.; Chew-Graham, C.; Bentall, R.P.; Morriss, R.K.; Peters, S.; Riste, L.; Richardson, G.; Lovell, K. (April 23, 2010). "Nurse led, home based self help treatment for patients in primary care with chronic fatigue syndrome: randomised controlled trial". BMJ. 340 (apr22 3): c1777–c1777. doi:10.1136/bmj.c1777. ISSN 0959-8138.
  3. ↑ Wearden, Alison J.; Appleby, Louis (September 1996). "Research on cognitive complaints and cognitive functioning in patients with chronic fatigue syndrome (CFS): What conclusions can we draw?". Journal of Psychosomatic Research. 41 (3): 197–211. doi:10.1016/0022-3999(96)00131-6.
  4. ↑ Morriss, R.K.; Wearden, A.J.; Battersby, L. (June 1997). "The relation of sleep difficulties to fatigue, mood and disability in chronic fatigue syndrome". Journal of Psychosomatic Research. 42 (6): 597–605. doi:10.1016/S0022-3999(97)89895-9.
  5. ↑ Wearden, A; Appleby, L. (January 1997). "Cognitive performance and complaints of cognitive impairment in chronic fatigue syndrome (CFS)". Psychol Med. 27 (1): 81–90.
  6. ↑ Strickland, Paul; Morriss, Richard; Wearden, Alison; Deakin, Bill (January 1998). "A comparison of salivary cortisol in chronic fatigue syndrome, community depression and healthy controls". Journal of Affective Disorders. 47 (1–3): 191–194. doi:10.1016/S0165-0327(97)00134-1.
  7. ↑ Morriss, Richard K; Wearden, Alison J (July 1998). "Screening instruments for psychiatric morbidity in chronic fatigue syndrome". Journal of the Royal Society of Medicine. 91 (7): 365–368. doi:10.1177/014107689809100706. ISSN 0141-0768.
  8. ↑ Wearden, Alison J.; Morriss, Richard K.; Mullis, Ricky; Strickland, P. L.; Pearson, David J.; Appleby, Louis; Campbell, Iain T.; Morris, Julie A. (June 1998). "Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome". British Journal of Psychiatry. 172 (6): 485–490. doi:10.1192/bjp.172.6.485. ISSN 0007-1250.
  9. ↑ Mullis, R.; Campbell, I.T.; Wearden, A.J.; Morriss, R.K.; Pearson, D.J. (October 1, 1999). "Prediction of peak oxygen uptake in chronic fatigue syndrome". British Journal of Sports Medicine. 33 (5): 352–356. doi:10.1136/bjsm.33.5.352. ISSN 0306-3674. PMC 1756205. PMID 10522640.
  10. ↑ Morriss, R.K; Ahmed, M; Wearden, A.J; Mullis, R; Strickland, P; Appleby, L; Campbell, I.T; Pearson, D (October 1999). "The role of depression in pain, psychophysiological syndromes and medically unexplained symptoms associated with chronic fatigue syndrome". Journal of Affective Disorders. 55 (2–3): 143–148. doi:10.1016/S0165-0327(98)00218-3.
  11. ↑ Cordingley, L.; Wearden, A.; Appleby, L.; Fisher, L. (August 2001). "The Family Response Questionnaire: a new scale to assess the responses of family members to people with chronic fatigue syndrome". Journal of Psychosomatic Research. 51 (2): 417–424. ISSN 0022-3999. PMID 11516763.
  12. ↑ Wearden, A; Riste, L; Dowrick, C; Chew-Graham, C; Bentall, R; Morriss, R; Peters, S; Dunn, G; Richardson, G (December 2006). "Fatigue Intervention by Nurses Evaluation – The FINE Trial. A randomised controlled trial of nurse led self-help treatment for patients in primary care with chronic fatigue syndrome: study protocol. [ISRCTN74156610]". BMC Medicine. 4 (1). doi:10.1186/1741-7015-4-9. ISSN 1741-7015.
  13. ↑ Chew-Graham, C.A.; Cahill, G.; Dowrick, C.; Wearden, A.; Peters, S. (July 1, 2008). "Using Multiple Sources of Knowledge to Reach Clinical Understanding of Chronic Fatigue Syndrome". The Annals of Family Medicine. 6 (4): 340–348. doi:10.1370/afm.867. ISSN 1544-1709.
  14. ↑ Wearden, A.J.; Dowrick, C.; Chew-Graham, C.; Bentall, R.P.; Morriss, R.K.; Peters, S.; Riste, L.; Richardson, G.; Lovell, K. (April 23, 2010). "Nurse led, home based self help treatment for patients in primary care with chronic fatigue syndrome: randomised controlled trial". BMJ. 340 (apr22 3): c1777–c1777. doi:10.1136/bmj.c1777. ISSN 0959-8138.
  15. ↑ Chew-Graham, Carolyn; Dowrick, Christopher; Wearden, Alison; Richardson, Victoria; Peters, Sarah (December 2010). "Making the diagnosis of Chronic Fatigue Syndrome/Myalgic Encephalitis in primary care: a qualitative study". BMC Family Practice. 11 (1). doi:10.1186/1471-2296-11-16. ISSN 1471-2296. PMC 2836312. PMID 20178588.
  16. ↑ Peters, Sarah; Wearden, Alison; Morriss, Richard; Dowrick, Christopher F; Lovell, Karina; Brooks, Joanna; Cahill, Greg; Chew-Graham, Carolyn (December 2011). "Challenges of nurse delivery of psychological interventions for long-term conditions in primary care: a qualitative exploration of the case of chronic fatigue syndrome/myalgic encephalitis". Implementation Science. 6 (1). doi:10.1186/1748-5908-6-132. ISSN 1748-5908.
  17. ↑ Wearden, A.J.; Dunn, G.; Dowrick, C.; Morriss, R.K. (September 2012). "Depressive symptoms and pragmatic rehabilitation for chronic fatigue syndrome". British Journal of Psychiatry. 201 (3): 227–232. doi:10.1192/bjp.bp.111.107474. ISSN 0007-1250.
  18. ↑ Hannon, Kerin; Peters, Sarah; Fisher, Louise; Riste, Lisa; Wearden, Alison; Lovell, Karina; Turner, Pam; Leech, Yvonne; Chew-Graham, Carolyn (December 2012). "Developing resources to support the diagnosis and management of Chronic Fatigue Syndrome/Myalgic Encephalitis (CFS/ME) in primary care: a qualitative study". BMC Family Practice. 13 (1). doi:10.1186/1471-2296-13-93. ISSN 1471-2296.
  19. ↑ The FINE Trial Writing group on behalf of the FINE Trial group; Richardson, Gerry; Epstein, David; Chew-Graham, Carolyn; Dowrick, Christopher; Bentall, Richard P; Morriss, Richard K; Peters, Sarah; Riste, Lisa (December 2013). "Cost-effectiveness of supported self-management for CFS/ME patients in primary care". BMC Family Practice. 14 (1). doi:10.1186/1471-2296-14-12. ISSN 1471-2296. PMC 3556109. PMID 23327355.
  20. ↑ Wearden, Alison J.; Emsley, Richard (2013). "Mediators of the effects on fatigue of pragmatic rehabilitation for chronic fatigue syndrome". Journal of Consulting and Clinical Psychology. 81 (5): 831–838. doi:10.1037/a0033561. ISSN 1939-2117.
  21. ↑ Brooks, Joanna M; Daglish, Julie; Wearden, Alison J (October 2013). "Attributions, distress and behavioural responses in the significant others of people with chronic fatigue syndrome". Journal of Health Psychology. 18 (10): 1288–1295. doi:10.1177/1359105312464670. ISSN 1359-1053.
  22. ↑ Bayliss, Kerin; Riste, Lisa; Fisher, Louise; Wearden, Alison; Peters, Sarah; Lovell, Karina; Chew-Graham, Carolyn (April 2014). "Diagnosis and management of chronic fatigue syndrome/myalgic encephalitis in black and minority ethnic people: a qualitative study". Primary Health Care Research & Development. 15 (02): 143–155. doi:10.1017/S1463423613000145. ISSN 1463-4236.
  23. ↑ Bayliss, Kerin; Goodall, Mark; Chisholm, Anna; Fordham, Beth; Chew-Graham, Carolyn; Riste, Lisa; Fisher, Louise; Lovell, Karina; Peters, Sarah; Wearden, Alison (December 2014). "Overcoming the barriers to the diagnosis and management of chronic fatigue syndrome/ME in primary care: a meta synthesis of qualitative studies". BMC Family Practice. 15 (1). doi:10.1186/1471-2296-15-44. ISSN 1471-2296. PMC 3973969. PMID 24606913.
  24. ↑ Brooks, Joanna; King, Nigel; Wearden, Alison (March 2014). "Couples' experiences of interacting with outside others in chronic fatigue syndrome: a qualitative study". Chronic Illness. 10 (1): 5–17. doi:10.1177/1742395312474478. ISSN 1742-3953.
  25. ↑ Band, Rebecca; Barrowclough, Christine; Wearden, Alison (September 2014). "The impact of significant other expressed emotion on patient outcomes in chronic fatigue syndrome". Health Psychology. 33 (9): 1092–1101. doi:10.1037/hea0000086. ISSN 1930-7810. PMC 4151798. PMID 25180548.
  26. ↑ Stenhoff, Alexandra Laura; Sadreddini, Shireen; Peters, Sarah; Wearden, Alison (February 2015). "Understanding medical students' views of chronic fatigue syndrome: A qualitative study". Journal of Health Psychology. 20 (2): 198–209. doi:10.1177/1359105313501534. ISSN 1359-1053.
  27. ↑ Goldsmith, Lucy P.; Dunn, Graham; Bentall, Richard P.; Lewis, Shôn W.; Wearden, Alison J. (December 14, 2015). Nater, Urs M (ed.). "Therapist Effects and the Impact of Early Therapeutic Alliance on Symptomatic Outcome in Chronic Fatigue Syndrome". PLOS ONE. 10 (12): e0144623. doi:10.1371/journal.pone.0144623. ISSN 1932-6203.
  28. ↑ Band, Rebecca; Wearden, Alison; Barrowclough, Christine (March 2015). "Patient Outcomes in Association With Significant Other Responses to Chronic Fatigue Syndrome: A Systematic Review of the Literature". Clinical Psychology: Science and Practice. 22 (1): 29–46. doi:10.1111/cpsp.12093. PMC 4654336. PMID 26617440.
  29. ↑ Band, Rebecca; Barrowclough, Christine; Emsley, Richard; Machin, Matthew; Wearden, Alison J. (September 2016). "Significant other behavioural responses and patient chronic fatigue syndrome symptom fluctuations in the context of daily life: An experience sampling study". British Journal of Health Psychology. 21 (3): 499–514. doi:10.1111/bjhp.12179.
  30. ↑ Bayliss, Kerin; Riste, Lisa; Band, Rebecca; Peters, Sarah; Wearden, Alison; Lovell, Karina; Fisher, Louise; Chew-Graham, Carolyn A (December 2016). "Implementing resources to support the diagnosis and management of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) in primary care: A qualitative study". BMC Family Practice. 17 (1). doi:10.1186/s12875-016-0453-8. ISSN 1471-2296.
  31. ↑ Harris, Kamelia; Band, Rebecca J.; Cooper, Hazel; Macintyre, Vanessa G.; Mejia, Anilena; Wearden, Alison J. (November 2016). "Distress in significant others of patients with chronic fatigue syndrome: A systematic review of the literature". British Journal of Health Psychology. 21 (4): 881–893. doi:10.1111/bjhp.12202.
  32. ↑ Russell, Charlotte; Kyle, Simon D.; Wearden, Alison J. (June 2017). "Do evidence based interventions for chronic fatigue syndrome improve sleep? A systematic review and narrative synthesis". Sleep Medicine Reviews. 33: 101–110. doi:10.1016/j.smrv.2016.05.001.
  33. ↑ Band, Rebecca; Barrowclough, Christine; Caldwell, Kim; Emsley, Richard; Wearden, Alison (March 2017). "Activity patterns in response to symptoms in patients being treated for chronic fatigue syndrome: An experience sampling methodology study". Health Psychology. 36 (3): 264–269. doi:10.1037/hea0000422. ISSN 1930-7810.

double blinded trial A clinical trial is double blinded if neither the participants nor the researchers know which treatment group they are allocated to until after the results are interpreted. This reduces bias. (Learn more: www.nottingham.ac.uk)

medically unexplained physical symptoms (MUPS) - Technically, this term means that no cause or explanation for the patient's symptoms has yet been found. However, patients diagnosed with "MUPS" are generally lumped into a psychosomatic, or psychologically-caused category by those in the medical profession, without any scientific basis for doing so.

randomized controlled trial (RCT) - A trial in which participants are randomly assigned to two groups, with one group receiving the treatment being studied and a control or comparison group receiving a sham treatment, placebo, or comparison treatment.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

BMJ The BMJ (previously the British Medical Journal) is a weekly peer-reviewed medical journal.

somatic symptom disorder A psychiatric term to describe an alleged condition whereby a person's thoughts somehow cause physical symptoms. The actual existence of such a condition is highly controversial, due to a lack of scientific evidence. It is related to other psychiatric terms, such as "psychosomatic", "neurasthenia", and "hysteria". Older terms include "somatization", "somatoform disorder", and "conversion disorder". Such terms refer to a scientifically-unsupported theory that claims that a wide range of physical symptoms can be created by the human mind, a theory which has been criticized as "mind over matter" parapsychology, a pseudoscience.

chronic illness any long-term illness, regardless of the severity. Chronic illnesses are typically incurable, requiring long-term management.

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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.

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