Cardiopulmonary exercise testing
Cardiopulmonary exercise testing (CPET) is a clinical tool to evaluate exercise capacity and predict outcome in patients with heart failure and other cardiac conditions.
Institute of Medicine (IOM) report on 2-day CPET
Although the Institute of Medicine report states that 2-day CPET is very reliable to objectively measure PEM, the IOM committee emphasized "that the CPET is not required to diagnose patients with ME/CFS. Further, this test carries substantial risk for these patients as it may worsen their condition (Nijs et al., 2010; VanNess et al., 2010)."
- Cardiopulmonary exercise testing and its application - NCBI
- Chapter 4, Review of the Evidence on Major ME/CFS Symptoms and Manifestations." Institute of Medicine. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness. Washington, DC: The National Academies Press, 2015. doi:10.17226/19012. Retrieved from http://www.nap.edu/read/19012/chapter/6?term=CPET#83