File:Microglia.JPG

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Microglia.JPG ‎(545 × 412 pixels, file size: 58 KB, MIME type: image/jpeg)

Title: Microglia and Neurons

Author: Gerry Shaw

Source: Microglia and neurons - Wikimedia

License: Attribution-ShareAlike 3.0 Unported CC BY SA 3.0

Description: Mixed rat brain cultures stained for coronin 1a, found in microglia here in green, and alpha-internexin, in red, found in neuronal processes. Antibodies and image generated by EnCor Biotechnology Inc.


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microglia A type of immune cell, called a macrophage, that lives in the brain. For historical reasons, macrophages have different names based on the part of the body that they normally live in. Macrophages that normally live in the blood are called monocytes. Macrophages that normally live in the skin are called Langerhans cells. Macrophages that normally live in the liver are called Kupffer cells. And macrophages that normally live in the central nervous system are called microglia. Microglia were originally classified as glial cells, under the assumption that the cells had a merely structural function, before it was realized that the cells were in fact immune cells. As the "sentinel cells" of the central nervous system, microglia survey their environment for abnormalities such as infection or tissue damage, and then initiate an immune response to fight the infection or repair the tissue damage.

microglia A type of immune cell, called a macrophage, that lives in the brain. For historical reasons, macrophages have different names based on the part of the body that they normally live in. Macrophages that normally live in the blood are called monocytes. Macrophages that normally live in the skin are called Langerhans cells. Macrophages that normally live in the liver are called Kupffer cells. And macrophages that normally live in the central nervous system are called microglia. Microglia were originally classified as glial cells, under the assumption that the cells had a merely structural function, before it was realized that the cells were in fact immune cells. As the "sentinel cells" of the central nervous system, microglia survey their environment for abnormalities such as infection or tissue damage, and then initiate an immune response to fight the infection or repair the tissue damage.

antibodies Antibody/immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

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current02:40, July 19, 2018Thumbnail for version as of 02:40, July 19, 2018545 × 412 (58 KB)MEcfsFMS (talk | contribs)Microglia Alzheimers progression (top): By National Institute on Aging [Public domain], Source: Wikimedia Commons

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