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===Chronic fatigue syndrome=== | ===Chronic fatigue syndrome=== | ||
* fatigue is the principal symptom: it is severe, disabling and affects physical and mental functioning; it should have been present for a minimum of 6 months during which it was present for more than 50% of the time. | * [[fatigue]] is the principal symptom: it is severe, disabling and affects physical and mental functioning; it should have been present for a minimum of 6 months during which it was present for more than 50% of the time. | ||
* other symptoms may be present: particularly myalgia, mood swings and sleep | * other symptoms may be present: particularly [[myalgia]], [[mood swings]] and [[sleep disturbance]]s. | ||
* definite onset of symptoms, not life-long. | * definite onset of symptoms, not life-long. | ||
* exceptions: patients with established medical conditions known to produce chronic fatigue; also patients with a current diagnosis of schizophrenia, manic depressive illness, substance abuse, eating disorder or proven organic brain disease. | * exceptions: patients with established medical conditions known to produce [[chronic fatigue]]; also patients with a current diagnosis of schizophrenia, manic depressive illness, substance abuse, eating disorder or proven organic brain disease. | ||
===Post-infectious Fatigue Syndrome (PIFS)=== | ===Post-infectious Fatigue Syndrome (PIFS)=== |
Revision as of 10:09, November 1, 2016
The Oxford criteria are a set of criteria for the diagnosis Chronic Fatigue Syndrome published in 1991 by a group of psychiatrists. They identify two broad syndromes and are used primarily for research purposes.[1] The Oxford criteria was used for PACE trial participation. [2][3]
Authors[edit | edit source]
Michael Sharpe, Len Archard, Jangu Banatvala, Leszek Borysiewicz, Anthony Clare, Anthony David, Richard Edwards, Keith Hawton, Harold Lambert, Russell Lane
Definition[edit | edit source]
Chronic fatigue syndrome[edit | edit source]
- fatigue is the principal symptom: it is severe, disabling and affects physical and mental functioning; it should have been present for a minimum of 6 months during which it was present for more than 50% of the time.
- other symptoms may be present: particularly myalgia, mood swings and sleep disturbances.
- definite onset of symptoms, not life-long.
- exceptions: patients with established medical conditions known to produce chronic fatigue; also patients with a current diagnosis of schizophrenia, manic depressive illness, substance abuse, eating disorder or proven organic brain disease.
Post-infectious Fatigue Syndrome (PIFS)[edit | edit source]
A sub-type of CFS which either follows an infection or is associated with a current infection (although whether such associated infection is of aetiological significance (i.e. whether it is the cause of the symptoms) is a topic for research).
To meet the research criteria for PIFS patients must:
- i. fulfil the criteria for CFS as defined above (i.e. the Oxford definition)
- ii. should also fulfil the following additional criteria:
- (a) There is definite evidence of infection at onset or presentation (a patient’s self-report is unlikely to be sufficiently reliable).
- (b) the syndrome is present for a minimum of 6 months after onset of infection.
- (c) the infection has been corroborated by laboratory evidence.
PDF for Oxford Definition CFS and PIFS[edit | edit source]
PDF: A report - chronic fatigue syndrome: guidelines for research - Journal of the Royal Society of Medicine - Volume 84 February 1991 118-121[4]
Criticisms[edit | edit source]
- Post-exertional malaise is not a listed symptom. When this symptom is not mandatory, patients with Chronic Fatigue and not the grossly misnamed disease Chronic Fatigue Syndrome are swept into the study.[5]
- Depression is not an absolute exception for a possible cause of Chronic Fatigue (not to be confused with Chronic Fatigue Syndrome.) This allows for patients with depression to be misdiagnosed with CFS[6]
- US NIH Report Calls for UK Definition of ME/CFS to be Scrapped - The Argus Report By: Penny Swift "The United States National Institutes of Health (NIH) has issued a draft report that highlights the dire need for scientific research that will help find a cure for the millions of people suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) worldwide. The report also highlights the fact that the decades-old UK Royal Society of Medicine’s Oxford criteria for ME/CFS are severely “flawed,” and that continuing to use these criteria may “cause harm.” Further, the NIH report says that the Royal Society definition should “be retired” and replaced with a single case definition agreed to by the ME/CFS community."[7]
Learn more[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- ↑ Symptoms and diagnosis of ME/CFS - ME Association
- ↑ Pace Trial - Centre for Psychiatry - QMUL
- ↑ PACE study results – Medical Research Council (UK) news report, 18 February 2011 - ME Association
- ↑ A report - chronic fatigue syndrome: guidelines for research Journal of the Royal Society of Medicine Volume 84 February 1991 118-121
- ↑ Chronic Fatigue is NOT Chronic Fatigue Syndrome - VOAT
- ↑ Chronic Fatigue Versus Chronic Fatigue Syndrome - About.com HEALTH By: Carol Eustice
- ↑ US NIH Report Calls for UK Definition of ME/CFS to be Scrapped - The Argus Report By: Penny Swift