Microbiome hypothesis

Evidence

• 2015, Support for the Microgenderome: Associations in a Human Clinical Population (see also Sex Differences in CFS Microbiome)
• 2015, Prevotella copri and the microbial pathogenesis of rheumatoid arthritis (March)
• 2016, A Role for the Intestinal Microbiota and Virome in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)(Full Text)

• 2018, Does the microbiome and virome contribute to myalgic encephalomyelitis/chronic fatigue syndrome? (Full Text)
• 2018, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in the era of the human microbiome: persistent pathogens drive chronic symptoms by interfering with host metabolism, gene expression and immunity (Abstract)

See also

• Probiotics
• Microbiome
• Simon Carding

virome The human virome is the collection of all viruses that are found in or on humans.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

virome The human virome is the collection of all viruses that are found in or on humans.

microbiome The full collection of microscopic organisms (especially bacteria and fungi) which are present in a particular environment, particularly inside the human body.