Bupropion: Difference between revisions

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==Theory ==
==Theory ==
Buproprion, like all antidepressants, does not address the underlying mechanisms of ME/CFS, so should not be regarded as a cure. It should be used only to reduce particular symptoms or treat a co-existing disorder (e.g. depression), and it is not a primary treatment for ME/CFS.<ref name="canadianconsensus-CCC">{{Citation | last1 = Carruthers    | first1 = Bruce M.  | authorlink1 = Bruce Carruthers  | last2 = Jain  | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir  | first3 = Kenny L.  | authorlink3 = Kenny De Meirleir | last4 = Peterson      | first4 = Daniel L.  | authorlink4 = Daniel Peterson | last5 = Klimas        | first5 = Nancy G.  | authorlink5 = Nancy Klimas | last6  = Lerner        | first6 = A. Martin  | authorlink6 = Martin Lerner | last7   = Bested        | first7 = Alison C.  | authorlink7 = Alison Bested | last8 = Flor-Henry    | first8 = Pierre    | authorlink8 = Pierre Flor-Henry  | last9 = Joshi | first9 = Pradip    | authorlink9 = Pradip Joshi | last10  = Powles | first10 = A C Peter | authorlink10 = A C Peter Powles | last11  = Sherkey| first11 = Jeffrey A.| authorlink11 = Jeffrey Sherkey | last12  = van de Sande  | first12 = Marjorie I.  | authorlink12 = Marjorie van de Sande  | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | pages = 7-115 | date = 2003| pmid =  | doi    = 10.1300/J092v11n01_02| url    = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref>
Buproprion, like all antidepressants, does not address the underlying mechanisms of ME/CFS, so should not be regarded as a cure. It should be used only to reduce particular symptoms or treat a co-existing disorder (e.g. depression), and it is not a primary treatment for ME/CFS.<ref name="canadianconsensus-CCC">{{Citation | last1 = Carruthers    | first1 = Bruce M.  | authorlink1 = Bruce Carruthers  | last2 = Jain  | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir  | first3 = Kenny L.  | authorlink3 = Kenny De Meirleir | last4 = Peterson      | first4 = Daniel L.  | authorlink4 = Daniel Peterson | last5 = Klimas        | first5 = Nancy G.  | authorlink5 = Nancy Klimas | last6  = Lerner        | first6 = A. Martin  | authorlink6 = Martin Lerner | last7 = Bested        | first7 = Alison C.  | authorlink7 = Alison Bested | last8 = Flor-Henry    | first8 = Pierre    | authorlink8 = Pierre Flor-Henry  | last9 = Joshi | first9 = Pradip    | authorlink9 = Pradip Joshi | last10  = Powles | first10 = A C Peter | authorlink10 = A C Peter Powles | last11  = Sherkey| first11 = Jeffrey A.| authorlink11 = Jeffrey Sherkey | last12  = van de Sande  | first12 = Marjorie I.  | authorlink12 = Marjorie van de Sande  | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | pages = 7-115 | date = 2003| pmid =  | doi    = 10.1300/J092v11n01_02| url    = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref>


ME/CFS patients may tolerate brand name bupropion better than generic versions due to sensitivities.{{Citation needed}}
ME/CFS patients may tolerate brand name bupropion better than generic versions due to sensitivities.{{Citation needed}}

Revision as of 21:26, October 8, 2022

Bupropion is an atypical antidepressant medication sold under the brand names include Wellbutrin, Aplenzin, and Zyban, and formerly Budeprion.[1][2][3] In addition to treating depression and severe pain, it is also used to treat seasonal affective disorder (SAD), and to reduce cravings in smoking cessation and drug addiction.[1][4]

Types[edit | edit source]

Bupropion is available in different forms, and may be combined with other drugs for particular uses, including

  • Bupropion for smoking cessation, brand name Zyban
  • Bupropion for major depression, brand name Wellbutrin[4]

Theory[edit | edit source]

Buproprion, like all antidepressants, does not address the underlying mechanisms of ME/CFS, so should not be regarded as a cure. It should be used only to reduce particular symptoms or treat a co-existing disorder (e.g. depression), and it is not a primary treatment for ME/CFS.[5]

ME/CFS patients may tolerate brand name bupropion better than generic versions due to sensitivities.[citation needed]

Evidence[edit | edit source]

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Costs and availability[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ 1.0 1.1 "Bupropion: MedlinePlus Drug Information". medlineplus.gov. Retrieved January 8, 2019.
  2. ↑ Cite error: Invalid <ref> tag; no text was provided for refs named PMC2729622
  3. ↑ Cite error: Invalid <ref> tag; no text was provided for refs named patch
  4. ↑ 4.0 4.1 https://www.drugs.com/bupropion
  5. ↑ Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, A C Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7–115, doi:10.1300/J092v11n01_02

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