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This page lists the recent as well as the ongoing registered medical trials on treatments for the symptoms of [[myalgic encephalomyelitis]] (ME) and [[Post-Acute Sequelae of COVID-19|post-acute sequelae of SARS-CoV-2 infection]] (PASC) as well as their results - if available. == Abbreviations == The following abbreviations are used in the tables below: {| class="wikitable" |+Trial type (TT) !Abbreviation !Meaning |- |NRCT |Non-randomized controlled trial |- |OLT |Open-label trial |- |RCT |Randomized controlled trial |} {| class="wikitable" |+Condition of the trial subjects (CS) !Abbreviation !Meaning |- |LC |Long COVID |- |ME |Myalgic encephalomyelitis |- |PC |Post COVID |} {| class="wikitable" |+Trial phase (TP) !Abbreviation !Meaning |- |1-4 |Trial phase 1-4 |- |n/a |Trial phase not applicable |} {| class="wikitable" |+Treatment category (TC) !Abbreviation !Meaning |- |C |Complementary and alternative medicine |- |D |Drug (pharmacotherapy) |- |O |Other |- |P |Psychotherapy |- |R |Rehabilitation |- |S |Supplements |} == Completed trials == {| class="wikitable sortable" !'''Study completion''' !TC !'''Treatment''' !Targeted symptoms !'''Link / study ID''' !Study results !'''TT''' !TP !CS |- |2022-01-19 |O |[[Biosound]] |many |[https://www.clinicaltrials.gov/study/NCT05848401 NCT05848401] | - |OLT |n/a |LC |- |2022-01-20 |O |[[Physical exercise]] & oxygen |cardiopulmonary |[https://www.clinicaltrials.gov/study/NCT04898205 NCT04898205] | |OLT |n/a |LC |- |2022-01-21 |O |[[Virtual SFCAMINA]] |many |[https://www.clinicaltrials.gov/study/NCT04593225 NCT04593225] | - |RCT |n/a |ME |- |2022-01-31 |D |[[Ruconest]] |neurological |[https://clinicaltrials.gov/study/NCT04705831 NCT04705831] | - |RCT |4 |PC |- |2022-01-31 |D |[[S-1226]] |respiratory |[https://clinicaltrials.gov/study/NCT04949386 NCT04949386] | - |RCT |2 |PC |- |2022-02-14 |S |Formula Cโข |many |[https://www.clinicaltrials.gov/study/NCT04828668 NCT04828668] |inconclusive[https://www.liebertpub.com/doi/abs/10.1089/can.2022.0135] |RCT |n/a |LC, PC |- |2022-02-22 |D |[[Fluvoxamine]] ([[SSRI]]) |parosmia |[https://clinicaltrials.gov/study/NCT05216614 NCT05216614] | - |RCT |2 |PC |- |2022-02-28 |R |[[Computerized cognitive training]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05571852 NCT05571852] | |OLT |n/a |LC, PC |- |2022-03-07 |D |[[Sodium pyruvate]] nasal spray |many |[https://www.clinicaltrials.gov/study/NCT04871815 NCT04871815] |headache-, coughing/sneezing-, hypoxemia-, dyspnea-[https://europeanjournalofrespiratorymedicine.com/wp-content/uploads/2021/03/EJRM-121.pdf] |OLT |2/3 |LC, PC |- |2022-03-10 |R |Inspiratory muscle training |pulmonary, strength |[https://www.clinicaltrials.gov/study/NCT04811859 NCT04811859] | |RCT |n/a |PC |- |2022-03-15 |S |[[Palmitoylethanolamide]] & [[Luteolin]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05311852 NCT05311852] | |RCT |n/a |LC |- |2022-03-30 |R |[[Rehabilitation]] (online) |respiratory, neurological |[https://www.clinicaltrials.gov/study/NCT05074771 NCT05074771] | |OLT |n/a |PC |- |2022-04-22 |C |[[Homeopathy]] |many |[https://www.clinicaltrials.gov/study/NCT05104749 NCT05104749] | |RCT |3 |LC, PC |- |2022-05-01 |R |[[Physical exercise]] (online) |pain, cardiopulmonary capacity, mood, quality of life |[https://www.clinicaltrials.gov/study/NCT04983394 NCT04983394] | |RCT |n/a |PC |- |2022-06-08 |D |[[Prospekta]] |asthenia |[https://www.clinicaltrials.gov/study/NCT05074888 NCT05074888] |negligible improvements[https://prospekta.ru/assets/s/%D0%A0%D0%B5%D0%B7%D1%83%D0%BB%D1%8C%D1%82%D0%B0%D1%82%D1%8B%20%D0%A0%D0%9A%D0%98%20%D0%9C%D0%9C%D0%9D-%D0%9C%D0%90%D0%A0-003_%D0%A2%D0%BA%D0%B0%D1%87%D0%B5%D0%B2%D0%B0_%D0%9E_%D0%9D__%D0%9C%D1%85%D0%B8%D1%82%D0%B0%D1%80%D1%8F%D0%BD_%D0%AD_%D0%90__%D0%9A%D0%BE%D0%BB%D1%8B%D1%85%D0%B0%D0%BB%D0%BE%D0%B2_%D0%98_%D0%92.pdf] |RCT |3 |PC |- |2022-06-29 |D |[[AXA1125]] |muscles, fatigue |[https://clinicaltrials.gov/study/NCT05152849 NCT05152849] |fatigue-[https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00123-2/fulltext] |RCT |2 |LC |- |2022-07-01 |R |[[Nordic walking]] |fatigue, quality of life |[https://www.clinicaltrials.gov/study/NCT05453188 NCT05453188] | |OLT |n/a |LC, PC |- |2022-07-18 |D |[[LYT-100]] |respiratory |[https://clinicaltrials.gov/study/NCT04652518 NCT04652518] | - |RCT |2 |PC |- |2022-07-30 |C |Laser [[acupuncture]] |immunological, dyspnea |[https://www.clinicaltrials.gov/study/NCT05271500 NCT05271500] | |RCT |n/a |PC |- |2022-07-31 |O |[[TDCS]] |fatigue, cognition, depression, quality of life |[https://www.clinicaltrials.gov/study/NCT05252481 NCT05252481] | |RCT |n/a |PC |- |2022-09-01 |O |[[Self-management]] |many |[https://www.clinicaltrials.gov/study/NCT05268523 NCT05268523] | |RCT |1/2 |LC, PC |- |2022-10-10 |S |[[Curcumin]] & [[Boswellia serrata]] & [[Vitamin C]] |many |[https://www.clinicaltrials.gov/study/NCT05150782 NCT05150782] | |OLT |n/a |LC, PC |- |2022-10-13 |O |Virtual self-management |many |[https://www.clinicaltrials.gov/study/NCT05107440 NCT05107440] | |OLT |n/a |LC |- |2022-10-14 |R |Cardiorespiratory telerehabilitation |many |[https://www.clinicaltrials.gov/study/NCT04996212 NCT04996212] | |RCT |n/a |LC, PC |- |2022-11-18 |S |Bioarginina C (supplement) |physical exhaustion, systemic inflammation, endothelial function |[https://www.clinicaltrials.gov/study/NCT04947488 NCT04947488] | |OLT |n/a |PC |- |2022-11-20 |R |High tone power therapy |fitness, fatigue |[https://www.clinicaltrials.gov/study/NCT05217771 NCT05217771] | |RCT |n/a |PC |- |2022-11-30 |R |Computerized cognitive training |fatigue, cognitive |[https://www.clinicaltrials.gov/study/NCT05582603 NCT05582603] | |OLT |2 |PC |- |2022-12-01 |R |Circuit training |fitness |[https://www.clinicaltrials.gov/study/NCT05323331 NCT05323331] | |RCT |n/a |PC |- |2022-12-04 |D |[[Probiotic]] |many |[https://www.clinicaltrials.gov/study/NCT05080244 NCT05080244] | - |RCT |n/a |LC |- |2022-12-05 |O |[[Vagus nerve stimulation]] |many |[https://www.clinicaltrials.gov/study/NCT05608629 NCT05608629] |mood+, fatigue-[https://www.clinicaltrials.gov/study/NCT05608629?tab=results] |OLT |n/a |ME |- |2022-12-10 |R |Diagrammatic breathing & resistance training |many |[https://www.clinicaltrials.gov/study/NCT05543551 NCT05543551] | |OLT |n/a |PC |- |2022-12-20 |R |Whole body vibration training |fitness, many |[https://www.clinicaltrials.gov/study/NCT05119634 NCT05119634] | |RCT |n/a |PC |- |2022-12-20 |D |[[Emoxypine]] & [[Meldonium]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05939622 NCT05939622] |fatigue-[https://www.sciencedirect.com/science/article/pii/S0753332223015214] |RCT |4 |PC |- |2022-12-30 |O |Pulsed ectromagnetic field / pulmonary rehabilitation |pulmonary |[https://www.clinicaltrials.gov/study/NCT05379517 NCT05379517] | |RCT |n/a |PC |- |2022-12-30 |R |[[Physiotherapy]] (online) |fitness, quality of life |[https://www.clinicaltrials.gov/study/NCT04742946 NCT04742946] | |OLT |n/a |LC |- |2022-12-31 |D |[[Oxaloacetate]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05273372 NCT05273372] |fatigue--[https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-022-03488-3] |RCT |n/a |ME |- |2022-12-31 |R |Multidisciplinary [[rehabilitation]] (online) |many |[https://www.clinicaltrials.gov/study/NCT04961333 NCT04961333] | |RCT |n/a |LC |- |2022-12-31 |O |[[Stellate ganglion block]] |many |[https://www.clinicaltrials.gov/study/NCT05812209 NCT05812209] | |OLT |n/a |LC |- |2023-01-04 |O |[[Vagus nerve stimulation]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05679505 NCT05679505] | |RCT |n/a |PC |- |2023-01-06 |D |[[Medical marijuana]] (CBD) |safety of CBD |[https://www.clinicaltrials.gov/study/NCT04997395 NCT04997395] | CBD is safe[https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.15988] |OLT |2 |LC |- |2023-01-12 |C |[[Homeopathy]] |cough, dyspnea, fatigue |[https://www.clinicaltrials.gov/study/NCT05715554 NCT05715554] | |OLT |n/a |PC |- |2023-01-15 |D |[[Loratidine]] |many |[https://ctri.nic.in/Clinicaltrials/pmaindet2.php?EncHid=NjgzMzM=&Enc=&userName=043679 CTRI/ 2022/07/043679] | - |RCT |4 |LC |- |2023-01-23 |D |[[Low dose naltrexone]] & [[NAD+]] |fatigue |[https://clinicaltrials.gov/study/NCT04604704 NCT04604704] | - |OLT |2 |PC |- |2023-01-31 |R |[[Balneotherapy]] & [[aquatic exercise]] |many |[https://www.clinicaltrials.gov/study/NCT05765591 NCT05765591] | |RCT |n/a |PC |- |2023-01-31 |S |[[Quercetin]] |many |[https://www.clinicaltrials.gov/study/NCT05730660 NCT05730660] |fatigue-, sleep issues-[https://www.sciencedirect.com/science/article/pii/S0753332223012519] |RCT |n/a |ME |- |2023-01-31 |S |[[ImmunoVita]] ([[:Category:Supplements|supplement]]) |many |[https://www.clinicaltrials.gov/study/NCT04301609 NCT04301609] |no significant improvements[https://www.mdpi.com/2072-6643/15/21/4504] |RCT |n/a |ME |- |2023-01-31 |R |Inspiratory muscle training |many |[https://www.clinicaltrials.gov/study/NCT05196529 NCT05196529] | - |OLT |n/a |PC, ME |- |2023-02-01 |R |Robotic assisted hand [[rehabilitation]] |health, independence, range of motion |[https://www.clinicaltrials.gov/study/NCT06137716 NCT06137716] | |OLT |n/a |PC, ME |- |2023-02-02 |R |Diaphragmatic exercises / incentive spirometer |pulmonary |[https://www.clinicaltrials.gov/study/NCT05787275 NCT05787275] | |RCT |n/a |PC |- |2023-02-22 |D |[[Vortioxetine]] ([[SSRI]]) |cognitive |[https://www.clinicaltrials.gov/study/NCT05047952 NCT05047952] |cognitive=[https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awad377/7344681] |RCT |2 |PC |- |2023-02-28 |R |Pulmonary [[rehabilitation]] |pulmonary |[https://www.clinicaltrials.gov/study/NCT05496842 NCT05496842] | |OLT |n/a |PC |- |2023-03-02 |O |Portable oxygen concentrator |pulmonary |[https://www.clinicaltrials.gov/study/NCT05212831 NCT05212831] | |OLT |n/a |LC |- |2023-03-23 |R |Pulmonary [[rehabilitation]] |pulmonary |[https://www.clinicaltrials.gov/study/NCT05402007 NCT05402007] | |RCT |n/a |LC, PC |- |2023-03-30 |O |[[Vagus nerve stimulation]] |neuropsychological |[https://www.clinicaltrials.gov/study/NCT05389592 NCT05389592] | |RCT |n/a |LC, PC |- |2023-03-31 |O |[[Vagus nerve stimulation]] |pain |[https://www.clinicaltrials.gov/study/NCT05205577 NCT05205577] | |OLT |n/a |LC |- |2023-03-31 |D |[[RSLV-132]] |fatigue |[https://clinicaltrials.gov/study/NCT04944121 NCT04944121] | - |RCT |2 |PC |- |2023-04-21 |S |[[Omega 3 fatty acid|Omega 3]] |many |[https://www.clinicaltrials.gov/study/NCT05121766 NCT05121766] | |RCT |1 |PC |- |2023-05-18 |D |[[Dextroamphetamine]] |fog |[https://www.clinicaltrials.gov/study/NCT05597722 NCT05597722] | - |RCT |4 |PC |- |2023-05-23 |O |[[Hydrogen water]] & [[biofeedback]] |many |[https://www.clinicaltrials.gov/study/NCT05397626 NCT05397626] | |OLT |1 |ME |- |2023-05-31 |R |Cardiopulmonary exercise |many |[https://www.clinicaltrials.gov/study/NCT05035628 NCT05035628] | |RCT |n/a |LC |- |2023-05-31 |R |[[Physical exercise]] |many |[https://www.clinicaltrials.gov/study/NCT05204511 NCT05204511] | |OLT |1 |LC, PC |- |2023-05-31 |R |[[Physical exercise]] |many |[https://www.clinicaltrials.gov/study/NCT06016192 NCT06016192] | |OLT |n/a |PC |- |2023-06-01 |C |[[Cupping therapy]] |immunological |[https://www.clinicaltrials.gov/study/NCT05901337 NCT05901337] | |OLT |n/a |PC |- |2023-06-01 |O |[[Hyperbaric oxygen therapy]] |pulmonary |[https://www.clinicaltrials.gov/study/NCT05977166 NCT05977166] | |OLT |n/a |PC |- |2023-06-06 |O |[[Plasma Exchange Therapy]] |many |[https://www.clinicaltrials.gov/study/NCT05445674 NCT05445674] | |RCT |2 |PC |- |2023-06-30 |P |[[Mindfulness and meditation|Mindfulness]] |many |[https://www.clinicaltrials.gov/study/NCT05566379 NCT05566379] | |OLT |n/a |LC, PC |- |2023-06-30 |P |Adhera (fatigue digital program) |many |[https://www.clinicaltrials.gov/study/NCT05483829 NCT05483829] [https://www.clinicaltrials.gov/study/NCT05631171 NCT05631171] | |OLT |n/a |LC |- |2023-07-06 |R |[[Osteopathy]] & [[Physiotherapy]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05012826 NCT05012826] | |RCT |n/a |LC |- |2023-07-21 |S |[[Lithium]] |fatigue, fog |[https://www.clinicaltrials.gov/study/NCT05618587 NCT05618587] | |RCT |2 |LC |- |2023-07-27 |D |[[TNX-102 SL]] |pain |[https://www.clinicaltrials.gov/study/NCT05472090 NCT05472090] | - |RCT |2 |PC |- |2023-07-30 |R |[[Physiotherapy]] with [[neuromodulation]] |fatigue, sleep, quality of life |[https://www.clinicaltrials.gov/study/NCT05681455 NCT05681455] | |RCT |n/a |PC |- |2023-07-31 |D |[[Valacyclovir]] & [[Celecoxib]] (IMC-2) |fatigue, pain, POTS |[https://ir.virios.com/news/press-releases/detail/100/virios-therapeutics-announcespositive-data-demonstrating Virios PR] [https://www.clinicaltrialsarena.com/news/virios-long-covid-antiviral/ CTA] | - |OLT |2 |PC |- |2023-07-31 |R |[[Resistance exercise]] |fitness, fatigue |[https://www.clinicaltrials.gov/study/NCT04900961 NCT04900961] | |OLT |n/a |LC |- |2023-07-31 |O |[[TDCS]] |many |[https://www.clinicaltrials.gov/study/NCT05780450 NCT05780450] | |OLT |n/a |LC, PC |- |2023-08-01 |R |Physical exercise (online) |fitness, sleep, anxiety, depression |[https://www.clinicaltrials.gov/study/NCT05381675 NCT05381675] | |RCT |n/a |PC |- |2023-08-02 |R |Cardiorespiratory [[rehabilitation]] (online) |fatigue, PEM, fitness |[https://www.clinicaltrials.gov/study/NCT05973136 NCT05973136] | |OLT |n/a |PC |- |2023-08-10 |C |[[Homeopathy]] |many |[https://www.clinicaltrials.gov/study/NCT06002230 NCT06002230] | |OLT |n/a |LC |- |2023-08-11 |D |[[PRS-220]] |pulmonary fibrosis |[https://www.clinicaltrials.gov/study/NCT05473533 NCT05473533] | - |RCT |1 | n/a |- |2023-08-30 |R |Sensory re-education training |disability, tactile sensation, handgrip strength |[https://www.clinicaltrials.gov/study/NCT05911113 NCT05911113] | |RCT |n/a |PC |- |2023-08-30 |R |Physical exercise |many |[https://www.clinicaltrials.gov/study/NCT05961462 NCT05961462] | |RCT |n/a |LC |- |2023-08-31 |R |[[Rehabilitation]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05599906 NCT05599906] | |OLT |n/a |LC |- |2023-08-31 |D |[[Montelukast]] |respiratory |[https://www.clinicaltrials.gov/study/NCT04695704 NCT04695704] | - |RCT |3 |LC |- |2023-09-01 |S |[[Magnesium]] & [[Vitamin D]] |many |[https://www.clinicaltrials.gov/study/NCT05630339 NCT05630339] | |RCT |n/a |PC |- |2023-09-12 |D |[[Metoprolol]] ([[beta blocker]]) |tachycardias, POTS, hypertension |[https://www.clinicaltrials.gov/study/NCT05096884 NCT05096884] | - |OLT |1 |PC |- |2023-09-12 |D |[[Nirmatrelvir]] & โ[[Ritonavir]] ([[Paxlovid]]) |many |[https://www.clinicaltrials.gov/study/NCT05576662 NCT05576662] | - |RCT |2 |PC |- |2023-09-22 |R |Inspiratory & expiratory muscle training |many |[https://www.clinicaltrials.gov/study/NCT05597774 NCT05597774] | |RCT |n/a |LC |- |2023-09-30 |R |Physical exercise |physical & mental fitness |[https://www.clinicaltrials.gov/study/NCT05848518 NCT05848518] | |RCT |n/a |LC, PC |- |2023-09-30 |P |[[Active coping]] |pain |[https://www.clinicaltrials.gov/study/NCT05894629 NCT05894629] | |RCT |n/a |PC |- |2023-09-30 |D |Sulfureous water |cardiopulmonary, inflammation |[https://clinicaltrials.gov/study/NCT06294756 NCT06294756] | |RCT |n/a |LC, PC |- |2023-10-01 |O |[[GET]] & [[Cognitive behavioral therapy|CBT]] |many |[https://www.clinicaltrials.gov/study/NCT05534997 NCT05534997] | |OLT |n/a |PC |- |2023-10-01 |D |[[Meplazumab]] |many |[https://www.clinicaltrials.gov/study/NCT05813587 NCT05813587] | |RCT |3 |PC |- |2023-10-04 |D |[[Somatropin]] (growth hormone) |hormonal |[https://clinicaltrials.gov/study/NCT03554265 NCT03554265] | |NRCT |3 |PC |- |2023-10-18 |D |[[Zofin]] |many |[https://clinicaltrials.gov/study/NCT05228899 NCT05228899] | |RCT |2 |LC |- |2023-10-30 |D |[[Vericiguat]] |fatigue, PEM |[https://clinicaltrials.gov/study/NCT05697640 NCT05697640] | |RCT |2 |PC |- |2023-10-31 |D |[[Medical marijuana]] |many |[https://www.clinicaltrials.gov/study/NCT05467904 NCT05467904] | |RCT |n/a |LC |- |2023-11-01 |D |IV [[Rintatolimod]] (Ampligen) |many |[https://clinicaltrials.gov/study/NCT05592418 NCT05592418] | |RCT |2 |PC, ME |- |2023-11-03 |D |[[Probiotic]]: VSL#3ยฎ |many |[https://www.clinicaltrials.gov/study/NCT05874089 NCT05874089] | |RCT |n/a |LC |- |2023-11-06 |O |[[Triphala]] & [[HIIT]] |immune system, oxidative stress |[https://www.clinicaltrials.gov/study/NCT06208761 NCT06208761] |inconclusive[https://www.clinicaltrials.gov/study/NCT06208761] |RCT |2 |LC |- |2023-11-14 |R |Physical and respiratory [[rehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT05629884 NCT05629884] | |OLT |n/a |LC, PC |- |2023-11-30 |R |[[Telerehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT05817032 NCT05817032] | |OLT |n/a |LC |- |2023-11-30 |P |[[Cognitive training]] |cognitive, anxiety, depression |[https://www.clinicaltrials.gov/study/NCT05629897 NCT05629897] | |OLT |n/a |LC, PC |- |2023-11-30 |P |[[Cognitive behavioral therapy|CBT]] & [[Mindfulness and meditation|mindfulness]] |pain, anxiety, depression, insomnia |[https://www.clinicaltrials.gov/study/NCT05815693 NCT05815693] | |OLT |n/a |LC, PC |- |2023-11-30 |C |[[Acupuncture]] |fog, cognitive |[https://www.clinicaltrials.gov/study/NCT06144320 NCT06144320] | |RCT |n/a |PC |- |2023-11-30 |R |[[Physiotherapy]] |many |[https://www.clinicaltrials.gov/study/NCT05040893 NCT05040893] | |OLT |n/a |LC |- |2023-12-01 |D |[[Pimozide]] |tinitus |[https://clinicaltrials.gov/study/NCT05507372 NCT05507372] | |OLT |n/a |PC |- |2023-12-11 |D |[[Probiotic]] |many |[https://www.clinicaltrials.gov/study/NCT05975034 NCT05975034] | |RCT |n/a |LC |- |2023-12-28 |C |[[Tai chi]] |strength |[https://www.clinicaltrials.gov/study/NCT05501067 NCT05501067] | |RCT |n/a |PC |- |2023-12-30 |D |[[Fampridine]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05274477 NCT05274477] | |RCT |n/a |PC |- |2023-12-30 |O |[[Stellate ganglion block]] & [[Bupivacaine]] |many |[https://www.clinicaltrials.gov/study/NCT05638620 NCT05638620] | |OLT |1 |LC, PC |- |2023-12-30 |C |[[Yoga]] & self-management |many |[https://www.clinicaltrials.gov/study/NCT05697042 NCT05697042] | |OLT |n/a |LC |- |2023-12-30 |R |[[Rehabilitation]] |fatigue |[https://www.clinicaltrials.gov/study/NCT04836351 NCT04836351] | |OLT |n/a |PC |- |2023-12-31 |D |Longidaza |pulmonary |[https://clinicaltrials.gov/study/NCT06383819 NCT06383819] | |RCT |3 |LC |- |2023-12-31 |O |[[Electrical stimulation]] |pain, fatigue, strength, endurance |[https://www.clinicaltrials.gov/study/NCT05200858 NCT05200858] | |RCT |n/a |LC, PC |- |2023-12-31 |D |[[Niagen]] |cognitive, depression, anxiety |[https://www.clinicaltrials.gov/study/NCT04809974 NCT04809974] | |RCT |4 |LC |- |2023-12-31 |R |[[Physical exercise]] |cardiopulmonary |[https://www.clinicaltrials.gov/study/NCT05566483 NCT05566483] | |OLT |n/a |LC |- |2023-12-31 |C |[[Yoga]] & breathing & [[meditation]] |many |[https://www.clinicaltrials.gov/study/NCT05139979 NCT05139979] | |RCT |n/a |LC, PC |- |2023-12-31 |D |[[Probiotic|Pre-probiotic]] |fatigue |[https://www.clinicaltrials.gov/study/NCT06013072 NCT06013072] | |RCT |n/a |PC |- |2023-12-31 |D |[[Remdesivir]] |many |[https://www.clinicaltrials.gov/study/NCT04978259 NCT04978259] | |OLT |4 |LC |- |2023-12-31 |D |[[CI-581a]], [[CI-581b]] ([[glutamate modulator]]) |depression |[https://www.clinicaltrials.gov/study/NCT05690503 NCT05690503] | |RCT |2 |PC |- |2023-12-31 |C |[[Tai chi|TaiChi-DTx]] (software) |cognitive, physical activity |[https://www.clinicaltrials.gov/study/NCT05419219 NCT05419219] | |OLT |n/a |LC |- |2023-12-31 |O |[[Hyperbaric oxygen therapy]] |pulmonary |[https://www.clinicaltrials.gov/study/NCT04905888 NCT04905888] | |open RCT |2 |LC |- |2023-12-31 |R |Respiratory music therapy |pulmonary, many |[https://www.clinicaltrials.gov/study/NCT05231512 NCT05231512] | |OLT |n/a |PC |- |2023-12-31 |S |[[Creatine]] |many |[https://www.clinicaltrials.gov/study/NCT02374112 NCT02374112] | |RCT |n/a |ME |- |2024-01-30 |O |[[Omega 3 fatty acid|Omega 3]] & Telerehabilitation |fatigue, fitness, depression, anxiety |[https://www.clinicaltrials.gov/study/NCT06063031 NCT06063031] | |RCT |n/a |PC |- |2024-01-31 |D |[[Beclomethasone]] |hyposmia |[https://www.clinicaltrials.gov/study/NCT05970731 NCT05970731] | |RCT |2 |LC, PC |- |2024-01-31 |D |[[Bupivacaine]] |many |[https://www.clinicaltrials.gov/study/NCT05664711 NCT05664711] | |OLT |1 |ME |- |2024-01-31 |R |Online respiratory [[physiotherapy]] |pulmonary |[https://www.clinicaltrials.gov/study/NCT05572346 NCT05572346] | |OLT |n/a |LC |- |2024-01-31 |R |Sub-symptom threshold [[Aerobic exercise|Aerobic rehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT06172803 NCT06172803] | |RCT |n/a |LC |- |2024-02-01 |C |[[Traditional Chinese medicine|Chinese herbal medicine]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05684952 NCT05684952] | |RCT |2 |LC |- |2024-02-01 |O |[[Autologous stem-cell transplantation]] |many |[https://www.clinicaltrials.gov/study/NCT05669261 NCT05669261] | |OLT |1 |LC, PC |- |2024-02-01 |P |[[Psychology]] |sleep, anxiety, depression |[https://www.clinicaltrials.gov/study/NCT05951803 NCT05951803] | |RCT |n/a |LC |- |2024-02-01 |D |[[Solriamfetol]] |fatigue, cognitive |[https://www.clinicaltrials.gov/study/NCT04622293 NCT04622293] | |RCT |4 |ME |- |2024-02-29 |R |Home-based physical training |fitness, fatigue, cognitive |[https://www.clinicaltrials.gov/study/NCT05360563 NCT05360563] | |OLT |n/a |PC |- |2024-02-29 |R |Cognitive [[rehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT05731570 NCT05731570] | |OLT |n/a |LC |- |2024-02-29 |P |[[Self-management]] |many |[https://www.clinicaltrials.gov/study/NCT05658536 NCT05658536] | |RCT |n/a |PC |- |2024-02-29 |O |[[Vagus nerve stimulation]] |dysautonomia, fatigue, dyspnea, PEM, quality of life |[https://www.clinicaltrials.gov/study/NCT05630040 NCT05630040] | |RCT |n/a |LC |- |2024-02-29 |R |[[Physical exercise]] / [[Incentive Spirometry|incentive spirometry]] |pulmonary, fitness |[https://www.clinicaltrials.gov/study/NCT06191367 NCT06191367] | |RCT |n/a |PC |- |2024-03-04 |O |Hi-OxSR Sequential Rebreathing mask |cognitive |[https://clinicaltrials.gov/study/NCT06379620 NCT06379620] | |OLT |1 |LC |- |2024-03-27 |R |[[Rehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT05855356 NCT05855356] | |RCT |n/a |PC |- |2024-03-30 |P |[[Psychology]] & [[breathing exercises]] |many |[https://www.clinicaltrials.gov/study/NCT05705154 NCT05705154] | |RCT |1/2 |LC |- |2024-03-31 |R |[[Heart rate variability]] & [[biofeedback]] |many |[https://www.clinicaltrials.gov/study/NCT05228665 NCT05228665] |general symptoms- [https://journals.sagepub.com/doi/full/10.1177/27536351241227261] |OLT |n/a |LC |- |2024-03-31 |P |[[Cognitive behavioral therapy]] |fitness, fatigue, anxiety, depression |[https://www.clinicaltrials.gov/study/NCT05196451 NCT05196451] | |RCT |n/a |PC |- |2024-03-31 |D |[[Nirmatrelvir]] & [[Ritonavir]] |many |[https://www.clinicaltrials.gov/study/NCT05823896 NCT05823896] | |RCT |2 |LC |- |2024-03-31 |R |Virtual home-based [[rehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT05298878 NCT05298878] | |OLT |n/a |LC |- |2024-03-31 |O |[[Nutrition]] & [[chronobiology]] & [[Exercise|physical exercise]] |many |[https://www.clinicaltrials.gov/study/NCT05719493 NCT05719493] | |OLT |n/a |ME |- |2024-03-31 |O |[[Ketogenic diet|Low carb diet]] |many |[https://www.clinicaltrials.gov/study/NCT05836402 NCT05836402] | |RCT |n/a |LC |- |2024-03-31 |O |[[Nutrition]] & physical [[rehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT05254301 NCT05254301] | |OLT |n/a |PC |- |2024-03-31 |O |[[Immunoadsorption]] |many |[https://www.clinicaltrials.gov/study/NCT05841498 NCT05841498] | |RCT |n/a |PC |- |2024-03-31 |D |[[BIO 300]] |respiratory |[https://www.clinicaltrials.gov/study/NCT04482595 NCT04482595] | |RCT |2 |PC |- |2024-04-20 |R |Inspiratory muscle training |health parameters, fatigue |[https://www.clinicaltrials.gov/study/NCT06091358 NCT06091358] | |OLT |n/a |LC |- |2024-04-30 |S |[[Oxaloacetate]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05840237 NCT05840237] | |RCT |n/a |LC |- |2024-04-30 |C |[[Bright light therapy|Bright light]] |fatigue, insomnia, anxiety, depression |[https://www.clinicaltrials.gov/study/NCT05677932 NCT05677932] | |RCT |n/a |LC |- |2024-04-30 |R |Home-based [[physical exercise]] |strength, fatigue, dyspnoea |[https://www.clinicaltrials.gov/study/NCT06073002 NCT06073002] | |OLT |n/a |LC |} == Ongoing trials == {| class="wikitable sortable" !'''Estimated study completion''' !TC !'''Treatment''' !Targeted symptoms !'''Link / study ID''' !'''TT''' !TP !CS |- |2024-05-31 |P |[[Psychoeducation]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05167266 NCT05167266] |OLT |n/a |LC |- |2024-05-31 |O |[[Hydroxy gas]] |many |[https://www.clinicaltrials.gov/study/NCT06159296 NCT06159296] |RCT |n/a |LC |- |2024-06-01 |D |[[Low dose naltrexone]] (oral) |pain, inflammation, fatigue |[https://clinicaltrials.gov/study/NCT05430152 NCT05430152] |RCT |2 |PC |- |2024-06-01 |D |[[Sirolimus]] |pulmonary fibrosis |[https://www.clinicaltrials.gov/study/NCT04948203 NCT04948203] |OLT |3 |COVID |- |2024-06-07 |R |Pulmonary rehabilitation (online) / physical activity |fitness |[https://www.clinicaltrials.gov/study/NCT05299333 NCT05299333] |RCT |n/a |PC |- |2024-06-15 |P |[[Amygdala and Insula Retraining Program|Amygdala & insula retraining]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05851846 NCT05851846] |OLT |n/a |LC |- |2024-06-28 |O |[[TDCS]] & [[Chlorella Pyreinodosa]] |biomarkers (B12, metilmalonic acid, homocysteine) |[https://clinicaltrials.gov/study/NCT06255600 NCT06255600] |RCT |n/a |LC |- |2024-06-28 |O |[[TDCS]] |many |[https://www.clinicaltrials.gov/study/NCT06074848 NCT06074848] |OLT |2 |PC |- |2024-06-30 |O |[[TDCS]] |fatigue, cognition, depression, sleep, pain |[https://www.clinicaltrials.gov/study/NCT05753202 NCT05753202] |OLT |n/a |PC |- |2024-06-30 |O |[[Faecal microbiota transplantation]] |sleep, anxiety, fatigue |[https://www.clinicaltrials.gov/study/NCT05556733 NCT05556733] |OLT |n/a |LC, PC |- |2024-06-30 |S |[[Vitamin K|Vitamin K2]] & [[Vitamin D|D3]] |biomarkers |[https://www.clinicaltrials.gov/study/NCT05356936 NCT05356936] |OLT |n/a |LC, PC |- |2024-06-30 |D |[[Temelimab]] |neuropsychiatric |[https://www.clinicaltrials.gov/study/NCT05497089 NCT05497089] |RCT |2 |PC |- |2024-06-30 |O |[[Hyperbaric oxygen therapy]] |many |[https://www.clinicaltrials.gov/study/NCT04842448 NCT04842448] |RCT |2 |PC |- |2024-06-30 |R |Virtual Reality |many |[https://clinicaltrials.gov/study/NCT06374446 NCT06374446] |RCT |n/a |LC |- |2024-06-30 |D |[[LAU-7b]] |many |[https://www.clinicaltrials.gov/study/NCT05999435 NCT05999435] |RCT |2/3 |LC |- |2024-06-30 |R |[[Breathing techniques]] & [[yoga]] |pulmonary, fatigue |[https://www.clinicaltrials.gov/study/NCT05732571 NCT05732571] |RCT |n/a |PC |- |2024-06-30 |O |[[Self-management]] |many |[https://clinicaltrials.gov/study/NCT06208696 NCT06208696] |NRCT |n/a |LC |- |2024-07-01 |D |[[Nirmatrelvir]] & โ[[Ritonavir]] ([[Paxlovid]]) |many |[https://www.clinicaltrials.gov/study/NCT05595369 NCT05595369] |RCT |2 |COVID, LC |- |2024-07-30 |R |[[Qigong exercise|Qigong]] |physical health |[https://www.clinicaltrials.gov/study/NCT05675995 NCT05675995] |OLT |n/a |LC, PC |- |2024-07-30 |S |[[Lithium]] |many |[https://www.clinicaltrials.gov/study/NCT06108297 NCT06108297] |OLT |1 |LC |- |2024-07-30 |S |[[Resveratrol]] & [[Quercetin]] |asthma, breathing |[https://www.clinicaltrials.gov/study/NCT05601180 NCT05601180] |RCT |n/a |LC |- |2024-07-31 |O |External encounter counterpulsation |fatigue |[https://www.clinicaltrials.gov/study/NCT05668039 NCT05668039] |RCT |n/a |LC |- |2024-07-31 |O |[[Vagus nerve stimulation]] |many |[https://www.clinicaltrials.gov/study/NCT05445427 NCT05445427] |OLT |n/a |PC |- |2024-07-31 |R |[[Incentive Spirometry|Incentive spirometry]] |many |[https://www.clinicaltrials.gov/study/NCT05813873 NCT05813873] |RCT |n/a |LC |- |2024-08-01 |O |[[GWAS]] (Genome-wide association study) |many |[https://www.decodeme.org.uk/our-gwas-data-analysis-plan/ DecodeME] |GWAS |n/a |ME |- |2024-08-31 |O |[[Hyperbaric oxygen therapy]] |many |[https://www.clinicaltrials.gov/study/NCT06159309 NCT06159309] |OLT |n/a |PC |- |2024-08-31 |C |[[Acupuncture]] & [[Traditional Chinese medicine|TCM]] |cognitive |[https://www.clinicaltrials.gov/study/NCT06042777 NCT06042777] |RCT |n/a |LC |- |2024-08-31 |D |[[Cetirizine]] / [[Famotidine]] |many |[https://www.clinicaltrials.gov/study/NCT05946551 NCT05946551] |RCT |3 |LC |- |2024-09-01 |D |[[Ivabradin]] |POTS |[https://www.clinicaltrials.gov/study/NCT05481177 NCT05481177] |RCT |4 |LC, PC |- |2024-09-01 |R |Pulmonary [[rehabilitation]] |pulmonary |[https://www.clinicaltrials.gov/study/NCT05244044 NCT05244044] |RCT |n/a |LC |- |2024-09-01 |R |Diaphragmatic breathing |many |[https://clinicaltrials.gov/study/NCT06330376 NCT06330376] |RCT |n/a |PC |- |2024-09-25 |O |[[Ultrasound]] |fatigue |[https://www.clinicaltrials.gov/study/NCT06189066 NCT06189066] |OLT |n/a |PC |- |2024-09-30 |P |[[Psychotherapy|Psychotherapeutic]] intervention |many |[https://www.clinicaltrials.gov/study/NCT05453201 NCT05453201] |OLT |n/a |LC, PC |- |2024-09-30 |O |Electronic case management (software) |many |[https://www.clinicaltrials.gov/study/NCT05019963 NCT05019963] |RCT |n/a |LC |- |2024-09-30 |R |[[Cognitive training]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05338749 NCT05338749] |OLT |n/a |LC, PC |- |2024-10-08 |R |[[Physical exercise]] (online) |fitness, cardiopulmonary, sleep |[https://www.clinicaltrials.gov/study/NCT05205460 NCT05205460] |RCT |n/a |PC |- |2024-10-31 |R |Inspiratory muscle training |fitness, blood pressure, neurovascular ctrl. |[https://www.clinicaltrials.gov/study/NCT06091384 NCT06091384] |RCT |n/a |PC |- |2024-10-31 |D |[[Nirmatrelvir]] & โ[[Ritonavir]] ([[Paxlovid]]) |many |[https://www.clinicaltrials.gov/study/NCT05668091 NCT05668091] |RCT |2 |LC |- |2024-10-31 |O |[[RegeneCyte]] |many |[https://www.clinicaltrials.gov/study/NCT05682560 NCT05682560] |RCT |2 |LC |- |2024-10-31 |R |[[Physical exercise]] |cardiopulmonary |[https://www.clinicaltrials.gov/study/NCT06065033 NCT06065033] |OLT |n/a |LC, PC |- |2024-10-31 |R |Multi-disciplinary recovery program |many |[https://www.clinicaltrials.gov/study/NCT05167227 NCT05167227] |RCT |n/a |LC |- |2024-10-31 |D |[[Valacyclovir]] & [[Celecoxib]] |fatigue |[https://clinicaltrials.gov/study/NCT06316843 NCT06316843] |RCT |2 |LC, PC |- |2024-11-30 |D |[[Efgartigimod]] |POTS |[https://www.clinicaltrials.gov/study/NCT05633407 NCT05633407] |RCT |2 |PC |- |2024-11-30 |O |[[Hydrogen water]] |fatigue, physical function, stress |[https://www.clinicaltrials.gov/study/NCT06227273 NCT06227273] |OLT |n/a |ME |- |2024-12-01 |R |NeuroFlex (brain training software) |cognitive, fatigue, depression |[https://www.clinicaltrials.gov/study/NCT05705193 NCT05705193] |OLT |n/a |LC |- |2024-12-01 |R |[[Cognitive rehabilitation]] |cognitive |[https://www.clinicaltrials.gov/study/NCT0567604 NCT0567604] |OLT |n/a |LC |- |2024-12-01 |O |[[Sauna]] |many |[https://www.clinicaltrials.gov/study/NCT05931497 NCT05931497] |OLT |n/a |LC |- |2024-12-15 |S |ImmuneRecov (proteins & supplements) |pulmonary |[https://www.clinicaltrials.gov/study/NCT06166030 NCT06166030] |OLT |3 |PC |- |2024-12-30 |R |[[Breathing exercises]] |blood oxygen level |[https://www.clinicaltrials.gov/study/NCT06165835 NCT06165835] |OLT |n/a |LC, PC |- |2024-12-31 |C |Multimodal integrative naturopathic therapy |many |[https://www.clinicaltrials.gov/study/NCT04927403 NCT04927403] |OLT |n/a |PC |- |2024-12-31 |O |[[Mindfulness and meditation|Mindfulness]] with Muse Sโข Headband |stress, anxiety |[https://www.clinicaltrials.gov/study/NCT05199233 NCT05199233] |OLT |n/a |PC |- |2024-12-31 |S |[[Prednisolone]] & [[Vitamin B1]], [[Vitamin B6|B6]] and [[Vitamin B12|B12]] |many |[https://www.clinicaltrials.gov/study/NCT05638633 NCT05638633] |RCT |3 |PC |- |2024-12-31 |O |[[Photobiomodulation]] |oral complaints |[https://www.clinicaltrials.gov/study/NCT05760092 NCT05760092] |RCT |2 |LC |- |2024-12-31 |R |Inspiratory muscle training |dyspnea |[https://www.clinicaltrials.gov/study/NCT05024474 NCT05024474] |RCT |n/a |LC, PC |- |2024-12-31 |R |[[Cognitive trainig]] & [[physical activity]] & [[Mindfulness and meditation|mindfulness]] |many |[https://www.clinicaltrials.gov/study/NCT05846126 NCT05846126] |RCT |n/a |LC, PC |- |2024-12-31 |D |[[Metformin]] |many |[https://www.clinicaltrials.gov/study/NCT06147050 NCT06147050] |RCT |3 |PC |- |2024-12-31 |D |[[Atorvastatin]] |neurocognitive |[https://www.clinicaltrials.gov/study/NCT04904536 NCT04904536] |OLT |3 |LC |- |2024-12-31 |D |[[Prednisolone]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05986422 NCT05986422] |RCT |2 |PC |- |2024-12-31 |S |Cacao [[flavonoid]] |fatigue, handgrip strength, perceived wellbeing |[https://www.clinicaltrials.gov/study/NCT06064838 NCT06064838] |OLT |n/a |LC |- |2024-12-31 |S |[[Melatonin]] & [[Zinc]] |many |[https://www.clinicaltrials.gov/study/NCT05454683 NCT05454683] |RCT |n/a |ME |- |2024-12-31 |R |[[Cardiopulmonary exercise test|Cardiopulmonary exercise]] |cardiopulmonary |[https://www.clinicaltrials.gov/study/NCT05539950 NCT05539950] |RCT |n/a |PC, ME |- |2024-12-31 |S |[[Sodium citrate]] |parosmia |[https://www.clinicaltrials.gov/study/NCT06204432 NCT06204432] |RCT |2 |PC |- |2024-12-31 |R |[[Physical exercise]] |many |[https://www.clinicaltrials.gov/study/NCT05094622 NCT05094622] |OLT |n/a |PC, ME |- |2024-12-31 |S |[[Floradapt Intensive GI]] ([[Probiotic]]) |GI inflammation, many |[https://www.clinicaltrials.gov/study/NCT06211062 NCT06211062] |RCT |2 |ME |- |2024-12-31 |R |Interrupted sitting |PEM, cognitive, quality of life |[https://www.clinicaltrials.gov/study/NCT05453175 NCT05453175] |RCT |n/a |LC |- |2025-01-15 |R |[[Chiropractic]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05693064 NCT05693064] |RCT |n/a |LC |- |2025-01-30 |O |[[Immunoadsorption|Repeat immunoadsorption]] |many |[https://www.clinicaltrials.gov/study/NCT05629988 NCT05629988] |OLT |n/a |PC, ME |- |2025-01-31 |O |[[CPAP]] |fog, neuropsychological |[https://www.clinicaltrials.gov/study/NCT06052514 NCT06052514] |OLT |n/a |PC |- |2025-01-31 |S |[[Nicotinamide riboside]] & [[MBRT]] |many |[https://www.clinicaltrials.gov/study/NCT05703074 NCT05703074] |RCT |2 |LC |- |2025-01-31 |O |[[TDCS]] |many |[https://www.clinicaltrials.gov/study/NCT05791812 NCT05791812] |OLT |n/a |ME |- |2025-02-15 |O |Umbilical cord mesenchymal [[stem cell therapy]] |caugh |[https://www.clinicaltrials.gov/study/NCT05808400 NCT05808400] |NRCT |n/a |LC |- |2025-02-28 |O |[[Immunoadsorption]] |many |[https://clinicaltrials.gov/study/NCT05710770 NCT05710770] |RCT |2 |PC, ME |- |2025-02-28 |S |[[Nitrate]] |physical fatigue |[https://www.clinicaltrials.gov/study/NCT05618574 NCT05618574] |OLT |3 |LC |- |2025-02-28 |D |[[DAOIB]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05764538 NCT05764538] |OLT |2 |LC |- |2025-02-28 |O |Cognitive training (online) |cognitive |[https://clinicaltrials.gov/study/NCT06391489 NCT06391489] |OLT |n/a |LC, PC |- |2025-03-01 |O |[[Vagus nerve stimulation]] |many |[https://www.clinicaltrials.gov/study/NCT05918965 NCT05918965] |OLT |n/a |LC |- |2025-03-30 |P |[[Cognitive behavioral therapy|CBT]] & [[Cognitive rehabilitation therapy|CRT]] |many |[https://www.clinicaltrials.gov/study/NCT05732285 NCT05732285] |OLT |n/a |many |- |2025-03-31 |O |Mild [[hyperthermia]] |many |[https://www.clinicaltrials.gov/study/NCT06204458 NCT06204458] |RCT |n/a |PC |- |2025-03-31 |S |[[Immulina TM|Immulina TM (]][[:Category:Supplements|supplement]]) |many |[https://www.clinicaltrials.gov/study/NCT05524532 NCT05524532] |RCT |n/a |PC, ME |- |2025-03-31 |O |[[Apollo wearable]] |many |[https://www.clinicaltrials.gov/study/NCT06097442 NCT06097442] |OLT |n/a |LC |- |2025-04-15 |P |[[Vimida]] (app) |fatigue, depression, anxiety, quality of life, ... |[https://clinicaltrials.gov/study/NCT06251518 NCT06251518] |RCT |n/a |PC |- |2025-04-30 |C |[[Acupuncture|Electro-acupuncture]] |many |[https://www.clinicaltrials.gov/study/NCT05890508 NCT05890508] |RCT |n/a |LC |- |2025-04-30 |P |[[Mindfulness and meditation|Mindfulness]] |mental health |[https://www.clinicaltrials.gov/study/NCT05676008 NCT05676008] |OLT |n/a |LC |- |2025-04-30 |S |[[N-acetylcysteine]] |many |[https://www.clinicaltrials.gov/study/NCT0454216 NCT0454216] |RCT |2 |ME |- |2025-05-15 |D |[[Amantadine]] |cognitive, mood |[https://www.clinicaltrials.gov/study/NCT06055244 NCT06055244] |OLT |1 |PC |- |2025-05-15 |D |Fluvoxamine |many |[https://www.clinicaltrials.gov/study/NCT05874037 NCT05874037] |RCT |2/3 |LC |- |2025-05-18 |D |[[Fluvoxamine]] & [[Metformin]] |fatigue |[https://www.clinicaltrials.gov/study/NCT06128967 NCT06128967] |RCT |3 |LC |- |2025-05-31 |D |[[BC007]] |many |[https://www.clinicaltrials.gov/study/NCT05911009 NCT05911009] |RCT |2 |PC |- |2025-05-31 |D |[[Efgartigimod]] |POTS |[https://www.clinicaltrials.gov/study/NCT05918978 NCT05918978] |OLT |2 |PC |- |2025-06-01 |S |[[Pycnogenol]] |many |[https://www.clinicaltrials.gov/study/NCT05890534 NCT05890534] |RCT |3 |PC |- |2025-06-01 |R |[[Physical exercise]] |many |[https://www.clinicaltrials.gov/study/NCT05877534 NCT05877534] |RCT |n/a |PC |- |2025-06-30 |R |[[Physical exercise]] |cardiovascular |[https://www.clinicaltrials.gov/study/NCT06168006 NCT06168006] |RCT |n/a |PC |- |2025-07-19 |C |[[Acupuncture]] |fatigue |[https://www.clinicaltrials.gov/study/NCT05212688 NCT05212688] |RCT |2 |LC |- |2025-07-30 |O |[[:Category:Diets|Diet]] & [[fasting]] |many |[https://www.clinicaltrials.gov/study/NCT06214455 NCT06214455] |OLT |n/a |LC |- |2025-07-31 |D |[[AER002]] |many |[https://www.clinicaltrials.gov/study/NCT05877508 NCT05877508] |RCT |2 |LC |- |2025-07-31 |R |[[Physical exercise]] (sensors + app) |fitness, quality of life |[https://www.clinicaltrials.gov/study/NCT05922865 NCT05922865] |OLT |n/a |LC |- |2025-07-31 |D |[[Modafinil]] & [[Solriamfetol]] & [[Melatonin]] & tailored lighing |sleep |[https://clinicaltrials.gov/study/NCT06404086 NCT06404086] |RCT |2 |LC, PC |- |2025-08-31 |O |[[Vagus nerve stimulation]] |fatigue |[https://www.clinicaltrials.gov/study/NCT06170645 NCT06170645] |RCT |n/a |ME |- |2025-08-31 |O |[[Hyperbaric oxygen therapy]] |neurocognitive |[https://www.clinicaltrials.gov/study/NCT06118138 NCT06118138] |OLT |n/a |PC |- |2025-08-31 |D |[[Anakinra]] |respiratory |[https://www.clinicaltrials.gov/study/NCT05926505 NCT05926505] |RCT |2/3 |LC, PC |- |2025-08-31 |O |[[Stellate ganglion block]] |parosmia |[https://clinicaltrials.gov/study/NCT06255600 NCT06255600] |RCT |2 |PC |- |2025-09-01 |D |[[VIX001]] |cognitive, neurological |[https://www.clinicaltrials.gov/study/NCT05947617 NCT05947617] |OLT |1 |LC, PC |- |2025-09-01 |R |[[Physical exercise]] |fatigue, fitness |[https://www.clinicaltrials.gov/study/NCT06142240 NCT06142240] |OLT |n/a |LC |- |2025-09-30 |P |Balance acceptance and commitment |many |[https://clinicaltrials.gov/study/NCT06231238 NCT06231238] |RCT |2 |LC, PC |- |2025-09-30 |R |Supervised computerized active program |cognitive, emotional, functional |[https://clinicaltrials.gov/study/NCT06315894 NCT06315894] |OLT |n/a |LC, PC |- |2025-10-31 |D |[[Melatonin]] & lighting |sleep |[https://clinicaltrials.gov/study/NCT06404112 NCT06404112] |RCT |2 |LC, PC |- |2025-11-01 |S |[[Ciwujia]] granules |many |[https://clinicaltrials.gov/study/NCT06245642 NCT06245642] |RCT |4 |ME |- |2025-11-01 |S |[[Testofen]] |many |[https://www.clinicaltrials.gov/study/NCT05795816 NCT05795816] |RCT |3 |LC |- |2025-11-30 |D |[[Modafinil]] & [[Solriamfetol]] |sleep |[https://clinicaltrials.gov/study/NCT06404099 NCT06404099] |RCT |2 |LC, PC |- |2025-12-01 |R |Physical and cognitive exercising |many |[https://www.clinicaltrials.gov/study/NCT05218174 NCT05218174] |RCT |n/a |LC, PC |- |2025-12-01 |D |[[Amantadine]] |cognitive, fatigue, anxiety, depression |[https://clinicaltrials.gov/study/NCT06234462 NCT06234462] |RCT |2 |LC |- |2025-12-01 |D |[[Remdesivir]] |many |[https://www.clinicaltrials.gov/study/NCT05911906 NCT05911906] |RCT |4 |LC |- |2025-12-15 |O |[[IVIG]] (immunotherapy) |neurological |[https://www.clinicaltrials.gov/study/NCT05350774 NCT05350774] |RCT |2 |PC |- |2025-12-20 |O |[[Mesenchymal stromal cell therapy|HB-adMSCs]] (allogeneic) |many |[https://clinicaltrials.gov/study/NCT05126563 NCT05126563] |RCT |2 |PC |- |2025-12-30 |O |[[Hyperbaric oxygen therapy]] |many |[https://www.clinicaltrials.gov/study/NCT06082518 NCT06082518] |OLT |n/a |PC |- |2025-12-31 |O |[[IVIG]] |many |[https://www.clinicaltrials.gov/study/NCT06159283 NCT06159283] |RCT |2 |LC, PC |- |2025-12-31 |R |Water-based activity |fatigue, cognitive |[https://www.clinicaltrials.gov/study/NCT06142253 NCT06142253] |OLT |n/a |LC |- |2025-12-31 |D |[[Imatinib]] / [[Infliximab]] |many |[https://clinicaltrials.gov/study/NCT05220280 NCT05220280] |OLT |4 |LC |- |2025-12-31 |R |[[Rehabilitation]] & exercise |fatigue |[https://www.clinicaltrials.gov/study/NCT06156176 NCT06156176] |RCT |n/a |LC, PC |- |2025-12-31 |D |[[Ensitrelvir]] |many |[https://www.clinicaltrials.gov/study/NCT06161688 NCT06161688] |RCT |2 |LC |- |2025-12-31 |C |Complementary & Integrative medicine online |many |[https://www.clinicaltrials.gov/study/NCT06004362 NCT06004362] |RCT |n/a |PC |- |2025-12-31 |D |[[Ibudilast]] |many |[https://www.clinicaltrials.gov/study/NCT05513560 NCT05513560] |RCT |3 |PC |- |2026-01-31 |R |Cardiopulmonary rehabilitation |many |[https://clinicaltrials.gov/study/NCT06404060 NCT06404060] |OLT |n/a |LC, PC |- |2026-01-31 |R |[[Pacing]] |many |[https://clinicaltrials.gov/study/NCT06404073 NCT06404073] |OLT |n/a |LC, PC |- |2026-01-31 |P |Mind body intervention |many |[https://www.clinicaltrials.gov/study/NCT06045338 NCT06045338] |OLT |n/a |LC |- |2026-02-28 |C |[[TCM]] |many |[https://www.clinicaltrials.gov/study/NCT06095258 NCT06095258] |RCT |2 |LC |- |2026-02-28 |O |[[Stem cell therapy]] |neurological |[https://www.clinicaltrials.gov/study/NCT06156241 NCT06156241] |OLT |1 |LC |- |2026-03-01 |S |[[Medium chain fatty acid|MCTs]] & [[Safflower oil]] |fog |[https://www.clinicaltrials.gov/study/NCT05705648 NCT05705648] |RCT |n/a |PC |- |2026-03-30 |R |Comprehensive [[rehabilitation]] |fatigue |[https://www.clinicaltrials.gov/study/NCT06156202 NCT06156202] |RCT |n/a |LC |- |2026-03-31 |D |[[AT1001]] ([[Larazotide]]) |many |[https://www.clinicaltrials.gov/study/NCT05747534 NCT05747534] |RCT |2 |LC |- |2026-03-31 |D |[[Lp299v]] |many |[https://www.clinicaltrials.gov/study/NCT05227170 NCT05227170] |RCT |n/a |LC, PC |- |2026-04-01 |O |[[Hyperbaric oxygen therapy]] |many |[https://clinicaltrials.gov/study/NCT06267300 NCT06267300] |RCT |3 |PC |- |2026-04-01 |P |[[Lightning Process]] |many |[https://www.clinicaltrials.gov/study/NCT05236465 NCT05236465] |OLT |n/a |ME |- |2026-04-28 |D |[[Nirmatrelvir]] & โ[[Ritonavir]] ([[Paxlovid]]) |many |[https://www.clinicaltrials.gov/study/NCT05852873 NCT05852873] |RCT |3 |PC |- |2026-05-15 |O |[[Stellate ganglion block]] |parosmia |[https://www.clinicaltrials.gov/study/NCT06055270 NCT06055270] |RCT |3 |PC |- |2026-06-01 |R |Breath control technique |many |[https://www.clinicaltrials.gov/study/NCT05851859 NCT05851859] |OLT |n/a |LC |- |2026-06-11 |D |[[Rapamycin]] |many |[https://clinicaltrials.gov/study/NCT06257420 NCT06257420] |OLT |n/a |ME |- |2026-06-30 |D |[[Pyridostigmine]] & [[Low dose naltrexone]] |PEM, pain, overall health |[https://clinicaltrials.gov/study/NCT06366724 NCT06366724] |RCT |2 |ME |- |2026-08-01 |R |[[Incentive Spirometry|Incentive spirometr]]<nowiki/>er respiratory training |respiratory |[https://www.clinicaltrials.gov/study/NCT06231225 NCT06231225] |OLT |n/a |LC |- |2026-12-01 |O |[[Diet]] & [[self-management]] (online) |many |[https://www.clinicaltrials.gov/study/NCT05057676 NCT05057676] |OLT |n/a |many |- |2026-12-31 |D |[[Low dose naltrexone]] |POTS |[https://www.clinicaltrials.gov/study/NCT05363514 NCT05363514] |RCT |4 | n/a |- |2028-01-31 |R |Smell training and trigeminal nerve stimulation |parosmia |[https://www.clinicaltrials.gov/study/NCT05855369 NCT05855369] |RCT |2/3 |LC, PC |- |2028-03-01 |D |[[Pregabalin]] |many |[https://www.clinicaltrials.gov/study/NCT05967052 NCT05967052] |RCT |2 |ME |- |2028-09-30 |O |Weight loss |fitness |[https://www.clinicaltrials.gov/study/NCT05880108 NCT05880108] |RCT |n/a |LC |- |2028-09-30 |O |[[Anti-inflammatory diets|Anti-inflammatory diet]] |fatigue, fitness |[https://www.clinicaltrials.gov/study/NCT05977179 NCT05977179] |RCT |n/a |LC, PC |- |2029-03-31 |R |Cognitive r[[Rehabilitation|ehabilitation]] |many |[https://www.clinicaltrials.gov/study/NCT06086379 NCT06086379] |RCT |n/a |LC, PC |- |2029-12-30 |D |[[Baricitinib]] |cognitive |[https://www.clinicaltrials.gov/study/NCT05858515 NCT05858515] |RCT |2 |PC |}
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