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Talk:Mast cell activation syndrome
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This review article may be helpful for expanding this page: http://www.ncbi.nlm.nih.gov/pubmed/23179866 --[[User:JenB|JenB]] ([[User talk:JenB|talk]]) 14:17, 14 February 2016 (PST) Also to add: ME/CFS + mast cell activation https://www.medscape.com/viewarticle/893858 Gender: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417946/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120457/ --[[User:JenB|JenB]] ([[User talk:JenB|talk]]) 13:13, 19 April 2018 (PDT) ==Treatments== The below is super prescriptive โย needs to be reframed so that it's not an instruction manual for how to self-treat. Also need to clean up the "doctor recommends" sections that have no citations and again, sound like treatment recommendations. --[[User:JenB|JenB]] ([[User talk:JenB|talk]]) 23:44, 22 April 2018 (PDT) ---- Treatment is in a stepwise basis: Step 1 - [[antihistamines]] and mast cell stabilizers + low-histamine diet Step 2 - more antihistamines (including prescription variants) and mast cell stabilizers and benzodiazepines Step 3 - cytotoxic treatments like [[Gleevec]] Alternative/integrative treatments include [[vagus nerve]]-assisting practices ([[yoga]], [[meditation]]); guided meditation for symptom control; frequency-specific microcurrent for revitalizing T1 helper cells and more. Because mast cell degranulation can be highly susceptible to stress, MCAS can become a vicious cycle, where the stress of the disease creates more symptoms of the disease. Treatment must be begun incrementally, adding only one medication at a time until tolerated. Reactions to medication are often actually reactions to a filler - the solution to this is to order medications from a compounding pharmacy or to try alternative brands. Once the patient has H1 and H2 blockers as well as mast cell stabilizers safely on board, treatment must be done continuously for 6-8 weeks before any real effect is to be expected. Once there is improvement, the full protocol must be followed for at least 1 year before patient can attempt to reduce medication numbers. ----
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