Brain-derived neurotrophic factor
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Brain-derived neurotrophic factor or BDNF is a protein in the neurotrophic family.[1] The name BDNF is also used to refer to the related gene that expresses BDNF.[1]
Function[edit | edit source]
ME/CFS[edit | edit source]
Notable studies[edit | edit source]
- 2020, DNA Methylation and Brain-Derived Neurotrophic Factor Expression Account for Symptoms and Widespread Hyperalgesia in Patients With Chronic Fatigue Syndrome and Comorbid Fibromyalgia[2] (Abstract)
See also[edit | edit source]
- Central sensitization
- Allodynia (pain on touch)
Learn more[edit | edit source]
- Epigenetic modification of BDNF and HDAC in pain and post-exertional malaise - ME Research UK
- Brain-derived neurotrophic factor (BDNF) as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? - Nijs et al 2015
- Epigenetics of the BDNF gene and its relevance for pain: an exploratory study - ME Research UK
- Brain-derived neurotrophic factor (BDNF) as a driving force behind central sensitization pain: a new therapeutic target? - Jo Nijs, Pain in Motion
References[edit | edit source]
- ↑ 1.0 1.1 Binder, Devin K.; Scharfman, Helen E. (September 2004). "Brain-derived Neurotrophic Factor". Growth factors (Chur, Switzerland). 22 (3): 123–131. doi:10.1080/08977190410001723308. ISSN 0897-7194. PMC 2504526. PMID 15518235.
- ↑ Polli, Andrea; Ghosh, Manosij; Bakusic, Jelena; Ickmans, Kelly; Monteyne, Dora; Velkeniers, Brigitte; Bekaert, Bram; Godderis, Lode; Nijs, Jo (November 2020). "DNA Methylation and Brain-Derived Neurotrophic Factor Expression Account for Symptoms and Widespread Hyperalgesia in Patients With Chronic Fatigue Syndrome and Comorbid Fibromyalgia". Arthritis & Rheumatology (Hoboken, N.J.). 72 (11): 1936–1944. doi:10.1002/art.41405. ISSN 2326-5205. PMID 32562379.
