Editing Viral onset hypothesis
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===Chronic infection=== | ===Chronic infection=== | ||
Some think that there may be a low grade, chronic infection whereby the initial virus continues to provoke an immune response, especially in key areas such as the [[gastrointestinal tract]], [[muscle]], and the [[brain]], [[brain stem]], and [[spinal cord]]; an example is [[enterovirus infection hypothesis|enterovirus infection]].{{citation needed | date = 2022}} | Some think that there may be a low grade, chronic infection whereby the initial virus continues to provoke an immune response, especially in key areas such as the [[gastrointestinal tract]], [[muscle]], and the [[brain]], [[brain stem]], and [[spinal cord]]; an example is [[enterovirus infection hypothesis|enterovirus infection]].{{citation needed|date=2022}} | ||
===Autoimmune disease=== | ===Autoimmune disease=== | ||
Some think that symptoms are caused by an [[inflammatory]] process that is triggered by an initial infection and continues even after the initial [[virus]] is no longer replicating. It is possible that [[ME/CFS]] is an [[autoimmune disease|autoimmune]] response that can be triggered by many different infections.{{citation needed | date = 2022}} | Some think that symptoms are caused by an [[inflammatory]] process that is triggered by an initial infection and continues even after the initial [[virus]] is no longer replicating. It is possible that [[ME/CFS]] is an [[autoimmune disease|autoimmune]] response that can be triggered by many different infections.{{citation needed|date=2022}} | ||
===Viral reactivation=== | ===Viral reactivation=== | ||
Some people think that an immune deficiency allows otherwise common or benign viruses to reactive after lying dormant, for instance [[Human herpesvirus 6]] and other common herpesviruses have been investigated.{{citation needed | date = 2022}} | Some people think that an immune deficiency allows otherwise common or benign viruses to reactive after lying dormant, for instance [[Human herpesvirus 6]] and other common herpesviruses have been investigated.{{citation needed|date=2022}} | ||
===Dysbiosis=== | ===Dysbiosis=== | ||
[[Viral infection]] may trigger intestinal [[dysbiosis]] leading to alterations in the [[immune system]] and [[gut-brain axis]] and causing the symptoms of the disease.{{citation needed | date = 2022}} | [[Viral infection]] may trigger intestinal [[dysbiosis]] leading to alterations in the [[immune system]] and [[gut-brain axis]] and causing the symptoms of the disease.{{citation needed|date=2022}} | ||
===Outbreaks=== | ===Outbreaks=== | ||
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==Evidence against == | ==Evidence against == | ||
===Bacterial and non-viral infections as causes === | ===Bacterial and non-viral infections as causes === | ||
There are many reports of non-viral infections e.g. bacterial infections or parasites leading to ME/CFS. Some of these have led to reported clusters and [[List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks|outbreaks]] of ME, for example a water poisoning with the parasite [[Giardia|Giardia lamblia]] caused the [[2004 Bergen, Norway outbreak]] and clusters of [[Q fever]] infections.{{citation needed | date = 2022}} | There are many reports of non-viral infections e.g. bacterial infections or parasites leading to ME/CFS. Some of these have led to reported clusters and [[List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks|outbreaks]] of ME, for example a water poisoning with the parasite [[Giardia|Giardia lamblia]] caused the [[2004 Bergen, Norway outbreak]] and clusters of [[Q fever]] infections.{{citation needed|date=2022}} | ||
===Non-infectious causes === | ===Non-infectious causes === | ||
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==Treatment== | ==Treatment== | ||
[[Antiviral]]s are suggested as a potential treatment, but is known not to be universally effective in ME/CFS.{{citation needed | date = 2022}} | [[Antiviral]]s are suggested as a potential treatment, but is known not to be universally effective in ME/CFS.{{citation needed|date=2022}} | ||
==See also== | ==See also== | ||
