Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Niacin
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
'''Niacin''' or vitamin B<sub>3</sub> is used to turn food into energy, and helps keep the nervous system, digestive system and skin healthy. Niacin may be bought over the counter, or used in higher doses on prescription for high cholesterol or in combination with niacinamide to treat pellegra (niacin deficiency).<ref name="drugs.com">{{Cite web|url=https://www.drugs.com/mca/niacin | title = Niacin|website=Drugs.com|language=en|access-date=2020-10-11}}</ref> Niacin is comprised of '''nicotinic acid''' and [[nicotinamide]]. '''Niacinamide''' and '''nicotinamide''' are water soluble B3.<ref name=mskcc>{{Cite web|url=https://www.mskcc.org/cancer-care/integrative-medicine/herbs/nicotinamide | title = Nicotinamide | last = Memorial Sloan Kettering Cancer Center | first = | authorlink = | date = | website = mskcc.org|language=en|archive-url=|archive-date=|url-status=|access-date=2020-10-11}}</ref> There are two co-enzyme forms: [[nicotinamide dinucleotide]] (NAD) and [[nicotinamide adenine dinucleotide phosphate]] (NADP). Both play an important role in energy transfer reactions in the [[metabolism]] of [[glucose]], [[fat]] and [[alcohol]]. ==== Nicotinamide dinucleotide (NAD) ==== NAD carries hydrogens and their [[Electron|electrons]] during [[metabolic]] reactions, including the pathway from the [[citric acid cycle]] to the [[ion transportation |electron transport]] chain. NADP is a coenzyme in lipid and [[nucleic acid]] synthesis. == Theory == == Evidence == ==ME/CFS== ==Risks and safety == Niacin is generally considered safe, but side effects may sometimes occur and may be serious. Side effects are more likely in prescription strength doses, e.g., 2,000-6,000mg per day. Side effects may include: *Severe skin flushing with [[dizziness]] *Rapid heartbeat (tachycardia) *Itching *[[Nausea]] and/or vomiting *Abdominal pain *Diarrhea *Gout *Liver damage *Diabetes *Worsening [[allergy|allergies]] *Increased [[:Category:Thyroid diseases|thyroid]] symptoms *[[hypotension|Low blood pressure]]<ref name=drugs.com /> == Cost and availability == Niacin and nicotinamide are available over the counter or on prescription. NAD is available over the counter.<ref name="drugs.com" /> ==See also== *[[B vitamin]]s * [[B vitamin complex]] *[[Nicotinamide adenine dinucleotide]] (NAD, NAD+ and NADH) *[[Dr Lapp's supplement recommendations]] ==Learn more== * [http://lpi.oregonstate.edu/mic/vitamins/niacin Niacin - Linus Pauling Institute Micronutrient Information Center] * [https://www.drugs.com/niacin.html Niacin] - drugs.com * [https://www.mskcc.org/cancer-care/integrative-medicine/herbs/nicotinamide Nicotinamide - Memorial Sloan Kettering Center Center] ==References== {{Reflist}} [[Category:Nutrients]] [[Category:B vitamins]] [[Category:Supplements]] [[Category:Potential treatments]] [[Category:Depression alternative treatments]] [[Category:Depression treatments]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
Template:Cite web
(
edit
)
Template:Main other
(
edit
)
Template:Reflist
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Citation/CS1
(
edit
)
Module:Citation/CS1/COinS
(
edit
)
Module:Citation/CS1/Configuration
(
edit
)
Module:Citation/CS1/Date validation
(
edit
)
Module:Citation/CS1/Identifiers
(
edit
)
Module:Citation/CS1/Utilities
(
edit
)
Module:Citation/CS1/Whitelist
(
edit
)
Module:No globals
(
edit
)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs