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Moderate myalgic encephalomyelitis or chronic fatigue syndrome
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'''Moderate myalgic encephalomyelitis''' or '''moderate chronic fatigue syndrome''' or '''moderate ME/CFS''' is a serious neurological disease, and should not be confused with either a moderate level of illness, or moderate [[fatigue]]. Moderate ME/CFS causes a severe level of disability, and some patients report deteriorating permanently to severe ME/CFS. ==NHS definition== Moderate ME/CFS People with moderate ME/CFS have reduced mobility and are restricted in all activities of daily living, although they may have peaks and troughs in their level of symptoms and ability to do activities. They have usually stopped work or education, and need rest periods, often resting in the afternoon for 1 or 2 hours. Their sleep at night is generally poor quality and disturbed.<ref name="ng206"/> The UK's [[National Health Service]] definition of moderate ME/CFS can be found within the 2021 [[NICE guidelines]].<ref name="ng206">{{Cite web|url=https://www.nice.org.uk/guidance/ng206 | title = Myalgic Encephalomyelitis (or Encephalopathy)/Chronic Fatigue Syndrome:diagnosis and management. NICE guideline. | last=NICE Guideline Development Group | first = | authorlink = |publisher=[[National Institute for Health and Care Excellence]] | date = 2021-10-29}}</ref> ==International Consensus Criteria == <ref name="ICC2011primer">{{citation | last1 = Carruthers | first1 = BM | authorlink1 = Bruce Carruthers | last2 = van de Sande | first2 = MI | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = KL | authorlink3 = Kenny de Meirleir | last4 = Klimas | first4 = NG | authorlink4 = Nancy Klimas | last5 = Broderick | first5 = G | authorlink5 = Gordon Broderick | last6 = Mitchell | first6 = T | authorlink6 = Terry Mitchell | last7 = Staines | first7 = D | authorlink7 = Donald Staines | last8 = Powles | first8 = ACP | authorlink8 = A C Peter Powles | last9 = Speight | first9 = N | authorlink9 = Nigel Speight | last10 = Vallings | first10 = R | authorlink10 = Rosamund Vallings | last11 = Bateman | first11 = L | authorlink11 = Lucinda Bateman | last12 = Bell | first12 = DS | authorlink12 = David Bell | last13 = Carlo-Stella | first13 = N | authorlink13 = Nicoletta Carlo-Stella | last14 = Chia | first14 = J | authorlink14 = John Chia | last15 = Darragh | first15 = A | authorlink15 = Austin Darragh | last16 = Gerken | first16 = A | authorlink16 = Anne Gerken | last17 = Jo | first17 = D | authorlink17 = Daehyun Jo | last18 = Lewis | first18 = DP | authorlink18 = Donald Lewis | last19 = Light | first19 = AR | authorlink19 = Alan Light | last20 = Light | first20 = KC | authorlink20 = Kathleen Light | last21 = Marshall-Gradisnik | first21 = S | authorlink21 = Sonya Marshall-Gradisnik | last22 = McLaren-Howard | first22 = J | authorlink22 = John McLaren-Howard | last23 = Mena | first23 = I | authorlink23 = Ismael Mena | last24 = Miwa | first24 = K | authorlink24 = Kunihisa Miwa | last25 = Murovska | first25 = M | authorlink25= Modra Murovska | last26 = Stevens | first26 = SR | authorlink26 = Staci Stevens | title = Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners | date = 2012| isbn = 978-0-9739335-3-6 | url = http://www.investinme.org/Documents/Guidelines/Myalgic%20Encephalomyelitis%20International%20Consensus%20Primer%20-2012-11-26.pdf}}</ref> ==Comparison == [[File:ME CFS severity quotes.jpg|thumb|alt=Mild severity: I walk...on Thursdays, Fridays. I've been quite ill (Andrew, 40s). The holiday travel exertion was too strenuous... I collapsed. (Wanda, 50s). Moderate severity: After trying to work for 14 days I became much worse (Yvonne, 30s). I tried to exercise and collapsed like a bunch of broccoli (Sue, 20s). Severe: You even get tired from speaking...from sitting (Wanda, 50s).]] ==Fluctuating level of symptoms == ==Invisible illness == ME/CFS is known as an invisible illness due to the lack of obvious physical signs of illness. ==Impact == ===Work and education === ===Care needs=== ===Mobility === ==People == British member of parliament [[Brynmor John]] appeared to have mild to moderate ME/CFS in 1988, but with some fluctuations. His ME/CFS improved enough to enable him to return to work but he struggled with walking, including being unable to walk up the slight incline on the road he lived on. He was not reliant on a wheelchair and did not need daily care. After his doctor advised him to [[exercise]] in order to aid his recovery from ME/CFS, Brynmor John visited the House of Commons gym one day after work, where he then [[Causes of death|collapsed and died soon after]]. ==Notable studies == *2015, Fatigue in adults with post-infectious fatigue syndrome: a qualitative content analysis<ref name="Stormorken2015">{{Cite web|first =Eva |last =Stormorken | authorlink = Eva Stormorken | first2 = Leonard A. | last2 = Jason | authorlink2 = Leonard Jason | first3 = Marit | last3 = Kirkevold| title = Fatigue in adults with post-infectious fatigue syndrome: a qualitative content analysis|journal =BMC Nursing |volume =14|pages = 64|url=https://bmcnurs.biomedcentral.com/articles/10.1186/s12912-015-0115-5| doi =10.1186/s12912-015-0115-5| pmid =26617466| pmc = PMC4662830}}</ref> - [https://bmcnurs.biomedcentral.com/articles/10.1186/s12912-015-0115-5 (Full text)] *2019, Physical activity patterns among children and adolescents with mild-to-moderate chronic fatigue syndrome/myalgic encephalomyelitis - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542452/ (Full text)] ==See also == *[[Brynmor John]] *[[Mild myalgic encephalomyelitis or chronic fatigue syndrome|Mild ME/CFS]] *[[Severe myalgic encephalomyelitis or chronic fatigue syndrome|Severe ME/CFS]] *[[Myalgic encephalomyelitis]] *[[Chronic fatigue syndrome]] *[[List of abnormal findings in chronic fatigue syndrome and myalgic encephalomyelitis]] *[[Ableism]] *[[Stigma and discrimination]] *[[Disability]] ==Learn more== ==References == {{Reflist}} [[Category:Severity definitions]] [[Category:Definitions]]
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