File:T-cells-naive-memory ME CFS.jpg

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Delineation of T cell naïve and memory cells in ME/CFS and MS patients and controls. CD4+ (A–E) and CD8+ (F–J) T cells were analysed for CD45RA and CCR7 co-expression to quantify proportions which were naïve CD45RA+CCR7+ (B,G), effector memory RA (TEMRA) CD45RA+CCR7− (C,H), effector memory CD45RA−CCR7− (D,I) or central memory CD45RA−CCR7+ T cells. The bars show the Mean and SD. Key: Healthy controls (C), multiple sclerosis (MS), mild/moderate ME/CFS (ME-M), and severely affected ME/CFS (ME-S).

Author: (or citation)[edit | edit source]

Cliff JM, King EC, Lee J-S, Sepúlveda N, Wolf A-S, Kingdon C, Bowman E, Dockrell HM, Nacul L, Lacerda E and Riley EM (2019) Cellular Immune Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Front. Immunol. 10:796. doi: 10.3389/fimmu.2019.00796

Figure 4

Source: (e.g. internet address)[edit | edit source]

https://www.frontiersin.org/articles/10.3389/fimmu.2019.00796/full

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T cell A type of white blood cell which is mostly produced or matured in the thymus gland (hence T-cell) and is involved in the adaptive immune response on a cellular level. Also known as a T lymphocyte. (Learn more: www.youtube.com)

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

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current13:31, June 27, 2020Thumbnail for version as of 13:31, June 27, 20201,084 × 471 (239 KB)Notjusttired (talk | contribs)==== Title: (or description) ==== Delineation of T cell naïve and memory cells in ME/CFS and MS patients and controls. CD4+ (A–E) and CD8+ (F–J) T cells were analysed for CD45RA and CCR7 co-expression to quantify proportions which were...

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