File:Mesenchymal-stem-cell-effects.png

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Summary[edit | edit source]

Title: (or description)[edit | edit source]

Immunomodulatory action of activated MSCs. Notes: Red arrow, stimulation; black arrow, suppression; blunt-ended arrow, direct inhibition.
Abbreviations: iDC, immature dendritic cell; IL, interleukin; HGF, hepatocyte growth factor; TGF-β, transforming growth factor-β; PGE-2, prostaglandin E2; IDO, indoleamine 2,3-dioxygenase; NO, nitric oxide; PD-L1, programmed death-ligand 1; hMSC, human mesenchymal stem cell; Treg, T regulatory; Th, T helper cell; CTL, cytotoxic T cell; mDC, mature dendritic cell; PD-1, programmed cell death protein 1; PMN, polymorphonuclear leukocyte; NK, Natural killer cell. Source: Zachar et al. [97].

Author: (or citation)[edit | edit source]

Victoria Moreno-Manzano and Elisa Oltra García (November 5th 2018). Culturing Adult Stem Cells for Cell-Based Therapeutics: Neuroimmune Applications, Cell Culture, Radwa Ali Mehanna, IntechOpen, DOI: 10.5772/intechopen.80714

Figure 4

Source: (e.g. internet address)[edit | edit source]

https://www.intechopen.com/books/cell-culture/culturing-adult-stem-cells-for-cell-based-therapeutics-neuroimmune-applications

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Licensing[edit | edit source]

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immunomodulator An immunomodulator is a substance that affects the functioning of the immune system

β β / Β. Greek letter beta (a symbol used in science), equivalent to "b".

indoleamine (IDO) - any derivatives of an indole (e.g., serotonin, tryptophan) that contain an amine group

indole (IDO) - a signalling molecule produced by bacteria as a result of metabolising tryptophan, found in the intestines

apoptosis a type of cell death in which a cell, in response to a threat, initiates a series of molecular steps that lead to its orderly death. This is one method the body uses to get rid of unneeded or abnormal cells. This form of cell suicide is also called programmed cell death.

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current01:07, March 7, 2021Thumbnail for version as of 01:07, March 7, 2021650 × 482 (257 KB)Notjusttired (talk | contribs)==== Title: (or description) ==== '''Immunomodulatory action of activated MSCs.''' Notes: Red arrow, stimulation; black arrow, suppression; blunt-ended arrow, direct inhibition.<br /> Abbreviations: iDC, immature dendritic cell; IL, interleukin;...

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