Isocitrate dehydrogenase

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Isocitrate dehydrogenase NADP+ or IDH2 is a protein involved in the citric acid (TCA) cycle function.

ME/CFS[edit | edit source]

A small study by Sweetman et al. (2020) found that IDH2 expression was decreased in patients with ME/CFS compared to healthy controls.[1]

Learn more[edit | edit source]

References[edit | edit source]

  1. Sweetman, Eiren; Kleffmann, Torsten; Edgar, Christina; de Lange, Michel; Vallings, Rosamund; Tate, Warren (September 24, 2020). "A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction". Journal of Translational Medicine. 18 (1): 365. doi:10.1186/s12967-020-02533-3. ISSN 1479-5876. PMC 7512220.