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		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=199401</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=199401"/>
		<updated>2022-11-12T07:09:58Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Conspiracy theories */ NOTES ON THE WORD CONSPIRACY THEORY&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name is an abbrevieation for &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Nefazodone]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other procedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums, especially scientific papers. We will also list names of people who have declared themselves PSSD specialists with references to their websites.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;!-- Some people would say that we should not say &amp;quot;conspiracy theories&amp;quot; but at this point I disagree. I agree the word is overused on Wikipedia left and right, they call everything &amp;quot;conspiracy theory&amp;quot; when they want public to believe it is not real and they also define &amp;quot;conspiracy theory&amp;quot; as &amp;quot;an explanation [...] when other explanations are more probable&amp;quot; which I would say is a dangerously wrong. People confuse theory with hypothesis. For example, creationists say theory of evolution is &amp;quot;just a theory&amp;quot; like if it was a hypothesis. Evolutionary biologists say there is tons of scientific evidence for this theory but also they don&#039;t stop using the word &amp;quot;theory&amp;quot; because &amp;quot;theory&amp;quot; actually means an explanation which is probably true.--&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=199399</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=199399"/>
		<updated>2022-11-12T06:17:03Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Abbbre&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name is an abbrevieation for &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Nefazodone]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other procedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums, especially scientific papers. We will also list names of people who have declared themselves PSSD specialists with references to their websites.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197004</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197004"/>
		<updated>2022-11-09T12:34:58Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Treatment */ t&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Nefazodone]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other procedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums, especially scientific papers. We will also list names of people who have declared themselves PSSD specialists with references to their websites.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197003</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197003"/>
		<updated>2022-11-09T12:34:22Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Treatment */ hdh&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Nefazodone]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other procedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums, especially scientific papers. We will also list names who have declared themselves PSSD specialists with references to their websites.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197002</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197002"/>
		<updated>2022-11-09T12:32:19Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Psychiatric drugs */ jsj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Nefazodone]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other procedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197001</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=197001"/>
		<updated>2022-11-09T12:29:31Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Treatment */ u&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other procedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196971</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196971"/>
		<updated>2022-11-07T11:56:26Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Society and culture */ hehhd&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other provedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196970</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196970"/>
		<updated>2022-11-07T11:55:47Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Other sections */ hhhh&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other provedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196969</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196969"/>
		<updated>2022-11-07T11:13:25Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Society and culture */ q&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other provedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]]) have no idea what can be added here but it was suggested by another user so maybe ask them&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196968</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196968"/>
		<updated>2022-11-07T11:12:53Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Studies */ t&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other provedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Society and culture==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;I ([[User:Pssd1|Pssd1]] ([[User talk:Pssd1|talk]]) 11:12, November 7, 2022 (UTC)) have no idea what can be added here but it was suggested by another user so maybe ask them&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196967</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196967"/>
		<updated>2022-11-07T11:02:06Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Q&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity, neuroplastic abnormalities, brain shrinkage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other provedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196966</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196966"/>
		<updated>2022-11-07T11:00:54Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hjj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
===Other causes===&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other provedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196965</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196965"/>
		<updated>2022-11-07T11:00:01Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hdjdj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Causes ==&lt;br /&gt;
&lt;br /&gt;
PSSD is most commonly caused by psychiatric drugs especially those that are marketed as &amp;quot;antidepressants&amp;quot;. List of them is below.&lt;br /&gt;
&lt;br /&gt;
===Psychiatric drugs===&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostics==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
===Case reports===&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as other provedures and protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196964</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196964"/>
		<updated>2022-11-07T10:36:31Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Diagnostic criteria&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Case reports==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to the Healy et al. 2021 paper&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196962</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196962"/>
		<updated>2022-11-07T10:28:09Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hyggg&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Case reports==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage info about various forums etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196961</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196961"/>
		<updated>2022-11-07T10:26:59Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:A&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Case reports==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Prevalence==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;A lot of stuff here, mainly content copied from Wikipedia articles.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196960</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196960"/>
		<updated>2022-11-07T10:16:52Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Grey text is just non encyclopedic content to be deleted eventually, it is here to help editors.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196959</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196959"/>
		<updated>2022-11-07T10:11:24Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Conspiracy theories&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content, information about how sterilizing conditions like homosexuality were removed from list of mental disorders, identity of the drug dealer Formerly98, Wikimedia Foundation being funded by pharmaceutical corporations etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196958</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196958"/>
		<updated>2022-11-07T10:09:11Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Recognition */ j&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Studies==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Info about fundraisers, Melcangi studies, Rxisk funded studies, Healy&#039;s studies, Maybe some PFS studies, older studies of SRIs causing reduction in sexuality or birth defects, the &amp;quot;55% still had SD&amp;quot; study etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Conspiracy theories==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Psychiatry and drug companies being linked to genocide, eugenics and nazis, frauds on clinical trials, insider knowledge and opinions from people like Goetsze, Breggin, Healy, etc. some anti-psychiatry content etc., information about how sterilizing conditions like homosexuality were removed from list of mental disorders etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196957</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196957"/>
		<updated>2022-11-07T09:58:57Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hdd&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
====Other causes====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references including from forums especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Other sections may be needed&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196956</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196956"/>
		<updated>2022-11-07T09:54:49Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Treatment */ r&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#aaaaaa&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references (at least one) especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
Other sections may be needed&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196955</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196955"/>
		<updated>2022-11-07T09:52:35Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Jdjdj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#888888&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references (at least one) especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
Other sections may be needed&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196954</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196954"/>
		<updated>2022-11-07T09:51:36Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hdhddj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==Pathological mechanism==&lt;br /&gt;
&lt;br /&gt;
Here we will add list of all those thoeries with some references to each of them such as: neuropathy, neurotransmitter damages, mitochondrial death, leaky gut, neurotoxicity from abnormal levels of neurotransmitter hormones, epigenetic alterations, reproductive toxicity etc.&lt;br /&gt;
&lt;br /&gt;
==Treatment==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;span style=&amp;quot;color:#555555&amp;quot;&amp;gt;Here we will add an extremely long list of substances as well as protocols but the list should be 75 to 300 items long and all of them have to have maximum amount of references (at least one) especially scientific papers.&amp;lt;/span&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Recognition==&lt;br /&gt;
&lt;br /&gt;
Here we will add info about Rxisk, EMA, PSSD network, drug leaflets, media coverage etc.&lt;br /&gt;
&lt;br /&gt;
==Other sections==&lt;br /&gt;
&lt;br /&gt;
Other sections may be needed&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196951</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196951"/>
		<updated>2022-11-07T08:55:29Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Q&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196950</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196950"/>
		<updated>2022-11-07T08:38:52Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Mo&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; &amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
&lt;br /&gt;
These links were moved to talk page since the English Wikipedia will probably not allow them. However non-English Wikipedias are likely to allow them.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196943</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196943"/>
		<updated>2022-11-07T07:27:53Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hssj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; &amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196939</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196939"/>
		<updated>2022-11-07T07:23:37Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:I&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;mark&amp;gt;&#039;&#039;&#039;IMPORTANT:&#039;&#039;&#039; &amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;&amp;lt;/mark&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196938</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196938"/>
		<updated>2022-11-07T07:20:47Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hddj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;{{highlight | IMPORTANT: }} &amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196937</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196937"/>
		<updated>2022-11-07T07:18:04Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Hshssj&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196936</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196936"/>
		<updated>2022-11-07T07:14:12Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Qqq&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;{{highlight|&amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;}}&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196935</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196935"/>
		<updated>2022-11-07T07:11:44Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Moved to talk page&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196934</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196934"/>
		<updated>2022-11-07T07:11:13Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Q&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;If you are considering to edit this article &amp;lt;b&amp;gt;read all [https://me-pedia.org/wiki/Talk:PSSD goals and guidelines]&amp;lt;/b&amp;gt; and follow them.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.com Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.com Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://facebook.com/groups/1813492682283042 Anhedonia and PSSD Facebook group]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org Surviving Antidepressants forum]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196923</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196923"/>
		<updated>2022-11-06T23:51:20Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.com Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.com Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://facebook.com/groups/1813492682283042 Anhedonia and PSSD Facebook group]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org Surviving Antidepressants forum]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196922</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196922"/>
		<updated>2022-11-06T23:50:22Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links */ fix&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.com Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.com Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://facebook.com/groups/1813492682283042]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org Surviving Antidepressants forum]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196921</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196921"/>
		<updated>2022-11-06T23:43:45Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Links&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* [[Agomelatine]]&lt;br /&gt;
* [[Amitriptiline]]&lt;br /&gt;
* [[Aripiprazole]]&lt;br /&gt;
* [[Atomoxetine]]&lt;br /&gt;
* [[Brexpiprazole]]&lt;br /&gt;
* [[Bupropion]]&lt;br /&gt;
* [[Citalopram]]&lt;br /&gt;
* [[Clomipramine]]&lt;br /&gt;
* [[Desvenlafaxine]]&lt;br /&gt;
* [[Duloxetine]]&lt;br /&gt;
* [[Escitalopram]]&lt;br /&gt;
* [[Fluoxetine]]&lt;br /&gt;
* [[Fluvoxamine]]&lt;br /&gt;
* [[Imipramite]]&lt;br /&gt;
* [[Mirtazapine]]&lt;br /&gt;
* [[Olanzapine]]&lt;br /&gt;
* [[Paroxetine]]&lt;br /&gt;
* [[Sertraline]]&lt;br /&gt;
* [[Trazodone]]&lt;br /&gt;
* [[Venlafaxine]]&lt;br /&gt;
* [[Vortioxetine]]&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org/ Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd/ PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.com Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.com Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com/ Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com/ Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org/ PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://facebook.com/groups/1813492682283042]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service/ &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org/ Surviving Antidepressants forum]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196920</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196920"/>
		<updated>2022-11-06T23:27:57Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links */ u&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org/ Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd/ PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.com Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.com Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com/ Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com/ Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org/ PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://facebook.com/groups/1813492682283042]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service/ &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org/ Surviving Antidepressants forum]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196919</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196919"/>
		<updated>2022-11-06T23:21:20Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Qq&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org/ Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd/ PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.org Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.org Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com/ Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com/ Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org/ PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://m.facebook.com/groups/1813492682283042?group_view_referrer=search PSSD Facebook group]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service/ &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org/ Surviving Antidepressants forum]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196918</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196918"/>
		<updated>2022-11-06T23:20:06Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Diagnostic criteria */ qqq&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org/ Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd/ PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.org Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.org Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com/ Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com/ Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org/ PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://m.facebook.com/groups/1813492682283042?group_view_referrer=search PSSD Facebook group]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service/ &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org/ Surviving Antidepressants forum&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196917</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196917"/>
		<updated>2022-11-06T23:19:14Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links finished&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org/ Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd/ PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.org Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.org Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com/ Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com/ Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.pfsnetwork.org/ PFS Network]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/jEVrjTz PSSD Support Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/QPWmZu3QBj Deya&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://discord.gg/6bRuTdxKDF Stefan&#039;s PSSD Discord Server]&lt;br /&gt;
&lt;br /&gt;
[https://m.facebook.com/groups/1813492682283042?group_view_referrer=search PSSD Facebook group]&lt;br /&gt;
&lt;br /&gt;
[https://livecortex.com/product/pssd-recovery-service/ &amp;quot;PSSD Recovery&amp;quot; Scam Service by Cortex Labs]&lt;br /&gt;
&lt;br /&gt;
[https://survivingantidepressants.org/ Surviving Antidepressants forum&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196914</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196914"/>
		<updated>2022-11-06T22:51:24Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links *&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org/ Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/post-ssri-sexual-dysfunction-pssd/ PSSD article on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.propeciahelp.org Propecia Help]&lt;br /&gt;
&lt;br /&gt;
[https://forum.propeciahelp.org Propecia Help forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/p/letteratura-medica-sulla-pssd.html PSSD literature list on Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://runagainstcastration.wordpress.com/ Run Against Castration blog]&lt;br /&gt;
&lt;br /&gt;
[https://momentsinmania.wordpress.com/ Moments in Mania Blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
PFS Network&lt;br /&gt;
&lt;br /&gt;
PSSD Support Discord Server&lt;br /&gt;
&lt;br /&gt;
Deya&#039;s PSSD Discord Server&lt;br /&gt;
&lt;br /&gt;
Stefan&#039;s PSSD Discord Server&lt;br /&gt;
&lt;br /&gt;
PSSD Facebook group&lt;br /&gt;
&lt;br /&gt;
PSSD Scam Service&lt;br /&gt;
&lt;br /&gt;
Surviving Antidepressants forum&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196913</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196913"/>
		<updated>2022-11-06T22:40:04Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links */ u&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
PSSD article on Rxisk&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
Propecia Help forum&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
PSSD literature list on Italian blog&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
Moments in Mania Blog&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
Propecia Help&lt;br /&gt;
&lt;br /&gt;
PFS Network&lt;br /&gt;
&lt;br /&gt;
PSSD Support Discord Server&lt;br /&gt;
&lt;br /&gt;
Deya&#039;s PSSD Research Discord Server&lt;br /&gt;
&lt;br /&gt;
Stefan&#039;s PSSD Discord Server&lt;br /&gt;
&lt;br /&gt;
PSSD Facebook group&lt;br /&gt;
&lt;br /&gt;
PSSD Scam Service&lt;br /&gt;
&lt;br /&gt;
Surviving Antidepressants forum&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196912</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196912"/>
		<updated>2022-11-06T22:32:02Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* Symptoms *&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Derealization&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Lack of imagination and fantasy&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Vision changes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196911</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196911"/>
		<updated>2022-11-06T22:26:24Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Vision changes&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD Forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD Reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at Pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at Philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at Psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD Lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196910</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196910"/>
		<updated>2022-11-06T22:22:54Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Heheh&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Vision changes&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196909</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196909"/>
		<updated>2022-11-06T22:21:31Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:External links */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Vision changes&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
[https://pssdlab.wordpress.com/ PSSD lab]&lt;br /&gt;
&lt;br /&gt;
[https://pssdcanada.squarespace.com/ PSSD Canada]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssd-uk.org/ PSSD United Kingdom]&lt;br /&gt;
&lt;br /&gt;
[https://pssd-hilfe.jimdofree.com/ PSSD Germany]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisyndrome.org/ PSSD Italy]&lt;br /&gt;
&lt;br /&gt;
[https://pssdnetwork.org/ PSSD Network]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196908</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196908"/>
		<updated>2022-11-06T22:19:01Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:External links */&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Vision changes&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
&lt;br /&gt;
Links below are mainly for use for research by editors of this article and will be forcibly removed from Wikipedia version of it.&lt;br /&gt;
&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
https://pssdlab.wordpress.com/&lt;br /&gt;
&lt;br /&gt;
https://pssdcanada.squarespace.com/&lt;br /&gt;
&lt;br /&gt;
https://www.pssd-uk.org/&lt;br /&gt;
&lt;br /&gt;
https://pssd-hilfe.jimdofree.com/&lt;br /&gt;
&lt;br /&gt;
https://postssrisyndrome.org/&lt;br /&gt;
&lt;br /&gt;
https://pssdnetwork.org/&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196907</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196907"/>
		<updated>2022-11-06T22:16:11Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links */ q&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Vision changes&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ PSSD literature list on Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction/ Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd/ PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality/ PSSD reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD/ PSSD at pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony/ PSSD irony at philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances/ PSSD at psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
https://pssdlab.wordpress.com/&lt;br /&gt;
&lt;br /&gt;
https://pssdcanada.squarespace.com/&lt;br /&gt;
&lt;br /&gt;
https://www.pssd-uk.org/&lt;br /&gt;
&lt;br /&gt;
https://pssd-hilfe.jimdofree.com/&lt;br /&gt;
&lt;br /&gt;
https://postssrisyndrome.org/&lt;br /&gt;
&lt;br /&gt;
https://pssdnetwork.org/&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196906</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196906"/>
		<updated>2022-11-06T22:10:07Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:Bla&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Changes in semen&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Vision changes&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ list of PSSD literature list]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ Another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality PSSD reality subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://pagan.fandom.com/wiki/PSSD PSSD at pagan wiki]&lt;br /&gt;
&lt;br /&gt;
[https://philosophy.fandom.com/wiki/The_PSSD_irony PSSD irony at philosophy wiki]&lt;br /&gt;
&lt;br /&gt;
[https://psychology.fandom.com/wiki/SSRIs_and_sexual_function_disturbances PSSD at psychology wiki]&lt;br /&gt;
&lt;br /&gt;
[https://youtube.com/results?sp=mAEA&amp;amp;search_query=Pssd PSSD on YouTube]&lt;br /&gt;
&lt;br /&gt;
[https://www.google.com/search?q=site%3Amedium.com+pssd PSSD on Medium]&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196905</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196905"/>
		<updated>2022-11-06T21:56:15Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links+&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ list of PSSD literature list]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD Italian blog]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ another PSSD blog]&lt;br /&gt;
&lt;br /&gt;
[https://area1255.blogspot.com/ Area1255 blog]&lt;br /&gt;
&lt;br /&gt;
[https://pssdblog.blogspot.com/ Sterilising the mentally ill]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssd PSSD subreddit]&lt;br /&gt;
&lt;br /&gt;
[https://www.reddit.com/r/pssdreality PSSD reality subreddit]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
	<entry>
		<id>https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196904</id>
		<title>PSSD</title>
		<link rel="alternate" type="text/html" href="https://me-pedia.org/w/index.php?title=PSSD&amp;diff=196904"/>
		<updated>2022-11-06T21:50:11Z</updated>

		<summary type="html">&lt;p&gt;Pssd1:/* External links aa&lt;/p&gt;
&lt;hr /&gt;
&lt;div&gt;&amp;lt;i&amp;gt;This page is far from ready. Please do not edit it unless you have been invited to do it in ways outside of this site.&amp;lt;/i&amp;gt;&lt;br /&gt;
&lt;br /&gt;
PSSD is a medical condition caused by previous use of certain substances. The name was derived from &amp;quot;Post-SSRI Sexual Dysfunction&amp;quot; because in most (not all) cases it is caused by SSRIs and sexual function is affected the most but it is not the only thing damaged.&lt;br /&gt;
&lt;br /&gt;
==Symptoms==&lt;br /&gt;
Following symptoms can be present in PSSD:&lt;br /&gt;
* Genital numbness which is reduced or absent genital sensation, especially erogenous sensation&lt;br /&gt;
* Erectile dysfunction&lt;br /&gt;
* Shrinkage/atrophy of penis/testicles/clitoris&lt;br /&gt;
* Decreased or absent vaginal lubrication&lt;br /&gt;
* Lack of pre-cum&lt;br /&gt;
* Difficulty achieving orgasm or premature ejaculation&lt;br /&gt;
* Pleasureless or weak orgasms&lt;br /&gt;
* Decreased or absent libido&lt;br /&gt;
* Reduced/absent response to sexual stimuli&lt;br /&gt;
* Decrease or loss of nocturnal/morning/spontaneous erections&lt;br /&gt;
* Reduced nipple sensitivity&lt;br /&gt;
* Flaccid glans during erection&lt;br /&gt;
* Difficulty concentrating&lt;br /&gt;
* Poor memory&lt;br /&gt;
* Derealization&lt;br /&gt;
* Depersonalization&lt;br /&gt;
* Anhedonia (inability to feel pleasure)&lt;br /&gt;
* Apathy&lt;br /&gt;
* Blunted affect (Flattened emotions)&lt;br /&gt;
* Loss of empathic and romantic feelings&lt;br /&gt;
* Insomnia or excessive daytime sleepiness.&lt;br /&gt;
* Intense anxiety or complete loss of the ability to feel anxiety.&lt;br /&gt;
* Numbness of body&lt;br /&gt;
* Loss of appetite, taste and smell&lt;br /&gt;
* Fatigue&lt;br /&gt;
* Lack of motivation&lt;br /&gt;
* Dryness of skin, mouth, and/or eyes&lt;br /&gt;
&lt;br /&gt;
PSSD is commonly misdiagnosed as a psychological problem, nocebo effect, or a mental illness such as depression or somatoform but in fact it is a iatrogenic biologically-induced medical condition.&lt;br /&gt;
&lt;br /&gt;
== Substances that cause this condition ==&lt;br /&gt;
Following drugs which have been used in psychiatry have been reported to cause this condition:&lt;br /&gt;
&lt;br /&gt;
* Agomelatine&lt;br /&gt;
* Amitriptiline&lt;br /&gt;
* Aripiprazole&lt;br /&gt;
* Atomoxetine&lt;br /&gt;
* Brexpiprazole&lt;br /&gt;
* Bupropion&lt;br /&gt;
* Citalopram&lt;br /&gt;
* Clomipramine&lt;br /&gt;
* Desvenlafaxine&lt;br /&gt;
* Duloxetine&lt;br /&gt;
* Escitalopram&lt;br /&gt;
* Fluoxetine&lt;br /&gt;
* Fluvoxamine&lt;br /&gt;
* Imipramite&lt;br /&gt;
* Olanzapine&lt;br /&gt;
* Paroxetine&lt;br /&gt;
* Sertraline&lt;br /&gt;
* Trazodone&lt;br /&gt;
* Venlafaxine&lt;br /&gt;
* Vortioxetine&lt;br /&gt;
&lt;br /&gt;
==== Other causes ====&lt;br /&gt;
This is the list of drugs, supplements, and topical products which also cause a condition which is either PSSD itself or something similar. For some of these substances a separate name is used for condition they cause.&lt;br /&gt;
&lt;br /&gt;
* 5HTP&lt;br /&gt;
* Abiraterone acetate&lt;br /&gt;
* Ashwagandha&lt;br /&gt;
* Bicalutamide&lt;br /&gt;
* Cyprotone acetate&lt;br /&gt;
* Dutasteride&lt;br /&gt;
* Enzalutamide&lt;br /&gt;
* Finasteride (&amp;quot;Post-Finasteride Syndrome&amp;quot;)&lt;br /&gt;
* Genistein&lt;br /&gt;
* Goserelin&lt;br /&gt;
* Isotretinion (&amp;quot;Post Accutane Syndrome&amp;quot;)&lt;br /&gt;
* Ketoconazole&lt;br /&gt;
* Leuprorelin&lt;br /&gt;
* MDMA&lt;br /&gt;
* Milk Thistle&lt;br /&gt;
* Minoxidil&lt;br /&gt;
* Nandrolone (&amp;quot;Deca Dick&amp;quot;)&lt;br /&gt;
* Resveratrol&lt;br /&gt;
* Rutin&lt;br /&gt;
* Sam-E&lt;br /&gt;
* Saw palmetto&lt;br /&gt;
* Spironolactone&lt;br /&gt;
* Tretinoin&lt;br /&gt;
* Triptorelin&lt;br /&gt;
&lt;br /&gt;
==Diagnostic criteria==&lt;br /&gt;
According to to the page with lead author being Dr. David Healy&amp;lt;ref&amp;gt;https://rxisk.org/wp-content/uploads/2022/02/jrs210023-1.pdf&amp;lt;/ref&amp;gt;, the diagnostic criteria is following:&lt;br /&gt;
&lt;br /&gt;
Necessary&lt;br /&gt;
&lt;br /&gt;
(1) Prior treatment with a serotonin reuptake inhibitor.&lt;br /&gt;
&lt;br /&gt;
(2) An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops.&lt;br /&gt;
&lt;br /&gt;
Additional&lt;br /&gt;
&lt;br /&gt;
(3) Enduring reduction or loss of sexual desire.&lt;br /&gt;
&lt;br /&gt;
(4) Enduring erectile dysfunction (males).&lt;br /&gt;
&lt;br /&gt;
(5) Enduring inability to orgasm or decreased sensation of pleasure during orgasm.&lt;br /&gt;
&lt;br /&gt;
(6) The problem is present for ≥3 months after stopping treatment.&lt;br /&gt;
&lt;br /&gt;
There should be&lt;br /&gt;
&lt;br /&gt;
(7) No evidence of pre-drug sexual dysfunction that matches the current profile.&lt;br /&gt;
&lt;br /&gt;
(8) No current medical conditions that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
(9) No current medication or substance misuse that could account for the symptoms.&lt;br /&gt;
&lt;br /&gt;
Ancillary sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• genital pain&lt;br /&gt;
&lt;br /&gt;
• reduced nipple sensitivity&lt;br /&gt;
&lt;br /&gt;
• decreased or loss of nocturnal erections (males)&lt;br /&gt;
&lt;br /&gt;
• reduced ejaculatory force (males)&lt;br /&gt;
&lt;br /&gt;
• flaccid glans during erection (males)&lt;br /&gt;
&lt;br /&gt;
• decreased vaginal lubrication (females).&lt;br /&gt;
&lt;br /&gt;
Ancillary non-sexual symptoms may include:&lt;br /&gt;
&lt;br /&gt;
• emotional numbing&lt;br /&gt;
&lt;br /&gt;
• depersonalization&lt;br /&gt;
&lt;br /&gt;
• other sensory problems involving skin, smell, taste or vision [1,3,21]&lt;br /&gt;
&lt;br /&gt;
• cognitive impairment.&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
[https://www.rxisk.org Rxisk]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/blog/ Rxisk blog]&lt;br /&gt;
&lt;br /&gt;
[https://www.pssdforum.org/ PSSD forum]&lt;br /&gt;
&lt;br /&gt;
[https://www.theresearchzone.com/blog/search/pssd PSSD articles on The Research Zone blog]&lt;br /&gt;
&lt;br /&gt;
[https://rxisk.org/pssd-literature/ list of PSSD literature list]&lt;br /&gt;
&lt;br /&gt;
[https://en.m.wikipedia.org/w/index.php?title=Post-SSRI_sexual_dysfunction&amp;amp;oldid=784353598 PSSD Wikipedia article (not current version)]&lt;br /&gt;
&lt;br /&gt;
[https://www.ergogenic.health/blog/pssd-cures-how-to-reverse-post-ssri-sexual-dysfunction Ergogenic Health PSSD article]&lt;br /&gt;
&lt;br /&gt;
[https://disfunzionisessualipostssri.blogspot.com/ PSSD blog 1]&lt;br /&gt;
&lt;br /&gt;
[https://postssrisexualdysfunction.blogspot.com/ PSSD blog 2]&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;/div&gt;</summary>
		<author><name>Pssd1</name></author>
	</entry>
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