MEpedia - User contributions [en]

Neurovision, Inc.

2022-06-20T18:26:00Z

Beth:Beth moved page Neurovision, Inc. to Neuroversion, Inc.:The name was misspelled

#REDIRECT [[Neuroversion, Inc.]]

Neuroversion, Inc.

2022-06-20T18:25:55Z

Beth:Beth moved page Neurovision, Inc. to Neuroversion, Inc.:The name was misspelled

{{NeedsImage}}
'''Neuroversion Inc.''' is a clinic offering interventional pain management in Anchorage, Alaska, [[United States]].<ref name="website">https://www.neuroversion.com/</ref>

==Research and notable publications==
*2022, Stellate ganglion block reduces symptoms of Long COVID: A case series<ref name="Liu2022">{{Cite journal|title=Stellate ganglion block reduces symptoms of Long COVID: A case series|date=2022-01-15|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653406/|journal=Journal of Neuroimmunology|volume=362|pages=577784|last=Liu|first=Luke D.|last2=Duricka|first2=Deborah L.|doi=10.1016/j.jneuroim.2021.577784|pmc=8653406|pmid=34922127|issn=0165-5728}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653406 (Full text)]

==Talks and interviews==

==Online presence==
*PubMed
*Twitter
*Facebook
*LinkedIn
*[https://www.neuroversion.com/ Website]
*YouTube
*Address:
::Neuroversion
::2925 Debarr Road, Suite 240
::Anchorage
::Alaska 99508
*Phone: (907) 339-4650
*Fax: (907) 339-4694

==See also==
*[[Long COVID]]
*[[Stellate ganglion block]]

==Learn more==
<!-- *Outside articles: e.g. Wikipedia, news or interviews

==References==
{{reflist}}

[[Category:Long COVID clinics]]
[[Category:United States clinics]]
[[Category:Clinics]]
[[Category:American clinics]]

Persistent infection hypothesis

2022-02-05T05:27:27Z

Beth:Fixed typo

{{stub}}
The '''persistent infection hypothesis''' or '''persistent viral infection theory''' is the hypothesis that [[myalgic encephalomyelitis]] is triggered and/or maintained by one or more persistent [[Virus|viruses]] or infections. This is in contrast to the [[Hit and run hypothesis|"hit and run" hypothesis]], which is that the infection triggers a disease process that continues long after the [[immune system]] has eradicated the initial infection.

==Theory==

==Evidence==

==Treatment==

== Notable studies ==
* 1992, [[Epstein-Barr virus|Epstein-Barr Virus]]-Related Persistent Erythema Multiforme in Chronic Fatigue Syndrome<ref>{{Cite journal|last=Rebora|first=Alfredo|last2=Loi|first2=Anna|last3=Romagnoli|first3=Marina|last4=Drago|first4=Francesco|date=1992-02-01|title=Epstein-Barr Virus-Related Persistent Erythema Multiforme in Chronic Fatigue Syndrome|url=https://jamanetwork.com/journals/jamadermatology/fullarticle/553839|journal=Archives of Dermatology|language=en|volume=128|issue=2|pages=217–222|doi=10.1001/archderm.1992.01680120089009|issn=0003-987X}}</ref> - [https://jamanetwork.com/journals/jamadermatology/article-abstract/553839 (Abstract)]
* 1993, Persistence of enterovirus RNA in muscle biopsy samples suggests that some cases of chronic fatigue syndrome result from a previous, inflammatory viral myopathy<ref>{{Cite journal|last=Bowles|first=N. E.|last2=Bayston|first2=T. A.|last3=Zhang|first3=H. Y.|last4=Doyle|first4=D.|last5=Lane|first5=R. J.|last6=Cunningham|first6=L.|last7=Archard|first7=L. C.|date=1993|title=Persistence of enterovirus RNA in muscle biopsy samples suggests that some cases of chronic fatigue syndrome result from a previous, inflammatory viral myopathy|url=https://www.ncbi.nlm.nih.gov/m/pubmed/8409778/|journal=Journal of Medicine|volume=24|issue=2-3|pages=145–160|issn=0025-7850|pmid=8409778}}</ref> - [https://www.ncbi.nlm.nih.gov/m/pubmed/8409778/ (Abstract)]
* 1999, Persistence of enteroviral RNA in chronic fatigue syndrome is associated with the abnormal production of equal amounts of positive and negative strands of enteroviral RNA<ref>{{Cite journal|last=Cunningham|first=Louise|last2=Bowles|first2=N. E.|last3=Lane|first3=R. J. M.|last4=Dubowitz|first4=V.|last5=Archard|first5=L. C.|date=1990|title=Persistence of enteroviral RNA in chronic fatigue syndrome is associated with the abnormal production of equal amounts of positive and negative strands of enteroviral RNA|url=https://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-71-6-1399|journal=Journal of General Virology|volume=71|issue=6|pages=1399–1402|doi=10.1099/0022-1317-71-6-1399}}</ref> - [https://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-71-6-1399 (Full text)]
* 2010, Acute enterovirus infection followed by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and viral persistence<ref>{{Cite journal|last=Chang|first=R.|author-link=|last2=Lee|first2=T.|author-link2=|last3=Voeller|first3=M.|author-link3=|last4=Chia|first4=A.|author-link4=|last5=Chia|first5=J.|author-link5=John Chia|author-link6=|date=2010-02-01|title=Acute enterovirus infection followed by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and viral persistence|url=https://jcp.bmj.com/content/63/2/165|journal=Journal of Clinical Pathology|language=en|volume=63|issue=2|pages=165–168|doi=10.1136/jcp.2009.070466|issn=0021-9746|pmid=19828908|quote=|via=}}</ref> - [https://jcp.bmj.com/content/63/2/165.full (Full text)]
* 2012, Can persistent Epstein-Barr virus infection induce chronic fatigue syndrome as a Pavlov reflex of the immune response?<ref>{{Cite journal|last=Agliari|first=Elena|last2=Barra|first2=Adriano|last3=Vidal|first3=Kristian Gervasi|last4=Guerra|first4=Francesco|date=2012-03-01|title=Can persistent Epstein–Barr virus infection induce chronic fatigue syndrome as a Pavlov reflex of the immune response?|url=https://doi.org/10.1080/17513758.2012.704083|journal=Journal of Biological Dynamics|volume=6|issue=2|pages=740–762|doi=10.1080/17513758.2012.704083|issn=1751-3758|pmid=22873615}}</ref> - [https://www.tandfonline.com/doi/full/10.1080/17513758.2012.704083 (Full text)]
* 2016, Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence<ref name="Brooks2016">{{Cite journal|last=Brooks|first=David G.|author-link=|last2=Smale|first2=Stephen T.|author-link2=|last3=Bensinger|first3=Steven J.|author-link3=|last4=Horwitz|first4=Marcus A.|author-link4=|last5=Kitchen|first5=Scott G.|author-link5=|last6=Torre|first6=Juan Carlos de la|author-link6=|last7=Wilson|first7=Elizabeth B.|last8=Snell|first8=Laura M.|last9=Elsaesser|first9=Heidi|date=2016-01-25|title=Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence|url=https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005356|journal=PLOS Pathogens|language=en|volume=12|issue=1|pages=e1005356|doi=10.1371/journal.ppat.1005356|issn=1553-7374|pmc = 4726812|pmid=26808628|quote=|via=|access-date=}}</ref> - [https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005356 (Full text)]
*2018, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in the era of the human microbiome: persistent pathogens drive chronic symptoms by interfering with host metabolism, gene expression and immunity<ref>{{Cite journal|last=Proal|first=Amy|author-link=Amy Proal|last2=Marshall|first2=Trevor|author-link2=Trevor Marshall|author-link3=|author-link4=|author-link5=|date=Nov 2018|title=Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in the era of the human microbiome: persistent pathogens drive chronic symptoms by interfering with host metabolism, gene expression and immunity|url=https://www.frontiersin.org/articles/10.3389/fped.2018.00373/full|journal=Frontiers in Pediatrics|volume=|issue=|pages=|quote=|via=|doi=10.3389/fped.2018.00373}}</ref> - [https://www.frontiersin.org/articles/10.3389/fped.2018.00373/full (Full text)]

==See also==

* [[Enteroviral infection hypothesis]]
* [[Hit and run hypothesis]]
* [[Viral onset hypothesis]]
* [[Virus]]

==Learn more==

==References==
<references />

[[Category:Medical hypotheses]]

Cervical spinal stenosis

2018-12-29T23:43:17Z

Beth:minor changes

'''Cervical spinal stenosis''' is a narrowing of the spinal canal in the neck. Its symptoms can included pain, numbness, tingling, weakness and other symptoms seen in [[Cervical Medullary Syndrome|cervical medullary syndrome]].

==Fibromyalgia==

A study of 270 patients with [[fibromyalgia]] found that 46% had cervical spinal stenosis and 20% [[chiari malformation]].<ref>{{Cite journal|last=Heffez|first=Dan S.|last2=Ross|first2=Ruth E.|last3=Shade-Zeldow|first3=Yvonne|last4=Kostas|first4=Konstantinos|last5=Shah|first5=Sagar|last6=Gottschalk|first6=Robert|last7=Elias|first7=Dean A.|last8=Shepard|first8=Alan|last9=Leurgans|first9=Sue E.|date=2004-04-09|title=Clinical evidence for cervical myelopathy due to Chiari malformation and spinal stenosis in a non-randomized group of patients with the diagnosis of fibromyalgia|url=https://link.springer.com/article/10.1007/s00586-004-0672-x|journal=European Spine Journal|language=en|volume=13|issue=6|pages=516–523|doi=10.1007/s00586-004-0672-x|issn=0940-6719|pmc=3476600|pmid=15083352}}</ref> A significant improvement in physical and mental well-being was found in patients with cervical stenosis who received surgery.<ref>{{Cite journal|last=Heffez|first=Dan S.|last2=Ross|first2=Ruth E.|last3=Shade-Zeldow|first3=Yvonne|last4=Kostas|first4=Konstantinos|last5=Morrissey|first5=Mary|last6=Elias|first6=Dean A.|last7=Shepard|first7=Alan|date=Sep 2007|title=Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200733/|journal=European Spine Journal|volume=16|issue=9|pages=1423–1433|doi=10.1007/s00586-007-0366-2|issn=0940-6719|pmc=2200733|pmid=17426987}}</ref> A second study found that 71% had cervical spinal cord compression.<ref>{{Cite journal|date=2008-07-01|title=Positional Cervical Spinal Cord Compression and Fibromyalgia: A Novel Comorbidity With Important Diagnostic and Treatment Implications|url=https://www.sciencedirect.com/science/article/pii/S1526590008004379|journal=The Journal of Pain|language=en|volume=9|issue=7|pages=613–622|doi=10.1016/j.jpain.2008.01.339|issn=1526-5900}}</ref>

It is important to note that in the past many patients were misdiagnosed with fibromyalgia when further testing would have revealed the true source of their pain; the 2010 (updated in 2016) American College of Rheumatology (ACR) criteria has helped to stop misdiagnoses.<ref>{{Cite news|url=http://nationalpainreport.com/fibromyalgia-expert-says-misdiagnosis-is-rampant-8832803.html|title=Fibromyalgia Expert Says Misdiagnosis is Rampant|date=2017-02-02|work=National Pain Report|access-date=2018-11-26|language=en-US}}</ref><ref>{{Cite news|url=https://www.webmd.com/fibromyalgia/guide/common-misdiagnoses-of-fibromyalgia#|title=Common Misdiagnoses of Fibromyalgia|last=|first=|date=|work=WebMD|access-date=2018-11-26|archive-url=|archive-date=|dead-url=|language=en-US}}</ref><ref>{{Cite web|url=https://www.integrativepractitioner.com/topics/news/fibromyalgia-misdiagnosis-what-else-could-it-be|title=Fibromyalgia Misdiagnosis: What Else Could it Be?|last=|first=|date=Jun 6, 2016|website=www.integrativepractitioner.com|language=en|archive-url=|archive-date=|dead-url=|access-date=2018-11-26}}</ref>

==ME/CFS==
A case study published by [[Peter Rowe]] found marked improvement of symptoms in three patients with severe [[myalgic encephalomyelitis]], [[orthostatic intolerance]] and cervical spinal stenosis.<ref>{{Cite journal|last=Rowe|first=Peter C.|last2=Marden|first2=Colleen L.|last3=Heinlein|first3=Scott|last4=Edwards|first4=Charles C.|date=2018-02-02|title=Improvement of severe myalgic encephalomyelitis/chronic fatigue syndrome symptoms following surgical treatment of cervical spinal stenosis|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796598/|journal=Journal of Translational Medicine|volume=16|doi=10.1186/s12967-018-1397-7|issn=1479-5876|pmc=5796598|pmid=29391028}}</ref>

== See also ==
* [[Craniocervical instability]]

== References ==
<references />
[[Category:Diagnoses]]
[[Category:Comorbidities]]

Muscle biopsy

2018-06-20T22:30:54Z

Beth:Added "Abstract" /* In postviral fatigue syndrome */

{{Stub}}

A '''muscle biopsy''' is a clinical procedure to remove a sample of muscle for examination.

==In ME/CFS==
1996. Sensory characterization of somatic parietal tissues in humans with chronic fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/8859904

Abstract: Patients with chronic fatigue syndrome (CFS) mainly complain of symptoms in the musculoskeletal domain (myalgias, fatigue). In 21 CFS patients the deep (muscle) versus superficial (skin, subcutis) sensitivity to pain was explored by measuring pain thresholds to electrical stimulation unilaterally in the deltoid, trapezius and quadriceps and overlying skin and subcutis in comparison with normal subjects. Thresholds in patients were normal in skin and subcutis but significantly lower than normal (hyperalgesia) in muscles (P < 0.001) in all sites. The selective muscle hypersensitivity corresponded also to fiber abnormalities at muscle biopsy (quadriceps) performed in nine patients which were absent in normal subjects (four cases): morphostructural alterations of the sarchomere, fatty degeneration and fibrous regeneration, inversion of the cytochrome oxidase/succinate dehydrogenase ratio, pleio/polymorphism and monstruosity of mitochondria, reduction of some mitochondrial enzymatic activities and increments of common deletion of 4977 bp of mitochondrial DNA 150-3000 times the normal values. By showing both sensory (diffuse hyperalgesia) and anatomical (degenerative picture) changes at muscle level, the results suggest a role played by peripberal mechanisms in the genesis of CFS symptoms. They would exclude the heightened perception of physiological signals from all districts hypothesized by some authors, especially as the hyperalgesia is absent in skin/subcutis.

Ongoing. The [[NIH Post-Infectious ME/CFS Study]] is currently running a sub-study on the muscle biopsies of up to 40 patients who meet the [[Canadian Consensus Criteria]] for ME/CFS, 20 controls, and 20 post-lyme patients.

==In postviral fatigue syndrome==
1991. Mitochondrial abnormalities in the postviral fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/1792865

Abstract: We have examined the muscle biopsies of 50 patients who had postviral fatigue syndrome (PFS) for from 1 to 17 years. We found mild to severe atrophy of type II fibres in 39 biopsies, with a mild to moderate excess of lipid. On ultrastructural examination, 35 of these specimens showed branching and fusion of mitochondrial cristae. Mitochondrial degeneration was obvious in 40 of the biopsies with swelling, vacuolation, myelin figures and secondary lysosomes. These abnormalities were in obvious contrast to control biopsies, where even mild changes were rarely detected. The findings described here provide the first evidence that PFS may be due to a mitochondrial disorder precipitated by a virus infection.

==See also==
*[[Notable studies]]
*[[Muscle fatigability]]
*[[Muscle weakness]]
*[[Muscle pain]]
*[[Muscle fasciculations]]
*[[Muscle twitches]]

==References==
<references>

</references>

[[Category:Tests]]

Muscle biopsy

2018-06-20T22:30:29Z

Beth:add "abstract" to clarify from where the paragraph about the study comes /* In ME/CFS */

{{Stub}}

A '''muscle biopsy''' is a clinical procedure to remove a sample of muscle for examination.

==In ME/CFS==
1996. Sensory characterization of somatic parietal tissues in humans with chronic fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/8859904

Abstract: Patients with chronic fatigue syndrome (CFS) mainly complain of symptoms in the musculoskeletal domain (myalgias, fatigue). In 21 CFS patients the deep (muscle) versus superficial (skin, subcutis) sensitivity to pain was explored by measuring pain thresholds to electrical stimulation unilaterally in the deltoid, trapezius and quadriceps and overlying skin and subcutis in comparison with normal subjects. Thresholds in patients were normal in skin and subcutis but significantly lower than normal (hyperalgesia) in muscles (P < 0.001) in all sites. The selective muscle hypersensitivity corresponded also to fiber abnormalities at muscle biopsy (quadriceps) performed in nine patients which were absent in normal subjects (four cases): morphostructural alterations of the sarchomere, fatty degeneration and fibrous regeneration, inversion of the cytochrome oxidase/succinate dehydrogenase ratio, pleio/polymorphism and monstruosity of mitochondria, reduction of some mitochondrial enzymatic activities and increments of common deletion of 4977 bp of mitochondrial DNA 150-3000 times the normal values. By showing both sensory (diffuse hyperalgesia) and anatomical (degenerative picture) changes at muscle level, the results suggest a role played by peripberal mechanisms in the genesis of CFS symptoms. They would exclude the heightened perception of physiological signals from all districts hypothesized by some authors, especially as the hyperalgesia is absent in skin/subcutis.

Ongoing. The [[NIH Post-Infectious ME/CFS Study]] is currently running a sub-study on the muscle biopsies of up to 40 patients who meet the [[Canadian Consensus Criteria]] for ME/CFS, 20 controls, and 20 post-lyme patients.

==In postviral fatigue syndrome==
1991. Mitochondrial abnormalities in the postviral fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/1792865

We have examined the muscle biopsies of 50 patients who had postviral fatigue syndrome (PFS) for from 1 to 17 years. We found mild to severe atrophy of type II fibres in 39 biopsies, with a mild to moderate excess of lipid. On ultrastructural examination, 35 of these specimens showed branching and fusion of mitochondrial cristae. Mitochondrial degeneration was obvious in 40 of the biopsies with swelling, vacuolation, myelin figures and secondary lysosomes. These abnormalities were in obvious contrast to control biopsies, where even mild changes were rarely detected. The findings described here provide the first evidence that PFS may be due to a mitochondrial disorder precipitated by a virus infection.

==See also==
*[[Notable studies]]
*[[Muscle fatigability]]
*[[Muscle weakness]]
*[[Muscle pain]]
*[[Muscle fasciculations]]
*[[Muscle twitches]]

==References==
<references>

</references>

[[Category:Tests]]

Muscle biopsy

2018-06-20T22:29:27Z

Beth:added 1996 study

{{Stub}}

A '''muscle biopsy''' is a clinical procedure to remove a sample of muscle for examination.

==In ME/CFS==
1996. Sensory characterization of somatic parietal tissues in humans with chronic fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/8859904

Patients with chronic fatigue syndrome (CFS) mainly complain of symptoms in the musculoskeletal domain (myalgias, fatigue). In 21 CFS patients the deep (muscle) versus superficial (skin, subcutis) sensitivity to pain was explored by measuring pain thresholds to electrical stimulation unilaterally in the deltoid, trapezius and quadriceps and overlying skin and subcutis in comparison with normal subjects. Thresholds in patients were normal in skin and subcutis but significantly lower than normal (hyperalgesia) in muscles (P < 0.001) in all sites. The selective muscle hypersensitivity corresponded also to fiber abnormalities at muscle biopsy (quadriceps) performed in nine patients which were absent in normal subjects (four cases): morphostructural alterations of the sarchomere, fatty degeneration and fibrous regeneration, inversion of the cytochrome oxidase/succinate dehydrogenase ratio, pleio/polymorphism and monstruosity of mitochondria, reduction of some mitochondrial enzymatic activities and increments of common deletion of 4977 bp of mitochondrial DNA 150-3000 times the normal values. By showing both sensory (diffuse hyperalgesia) and anatomical (degenerative picture) changes at muscle level, the results suggest a role played by peripberal mechanisms in the genesis of CFS symptoms. They would exclude the heightened perception of physiological signals from all districts hypothesized by some authors, especially as the hyperalgesia is absent in skin/subcutis.

Ongoing. The [[NIH Post-Infectious ME/CFS Study]] is currently running a sub-study on the muscle biopsies of up to 40 patients who meet the [[Canadian Consensus Criteria]] for ME/CFS, 20 controls, and 20 post-lyme patients.

==In postviral fatigue syndrome==
1991. Mitochondrial abnormalities in the postviral fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/1792865

We have examined the muscle biopsies of 50 patients who had postviral fatigue syndrome (PFS) for from 1 to 17 years. We found mild to severe atrophy of type II fibres in 39 biopsies, with a mild to moderate excess of lipid. On ultrastructural examination, 35 of these specimens showed branching and fusion of mitochondrial cristae. Mitochondrial degeneration was obvious in 40 of the biopsies with swelling, vacuolation, myelin figures and secondary lysosomes. These abnormalities were in obvious contrast to control biopsies, where even mild changes were rarely detected. The findings described here provide the first evidence that PFS may be due to a mitochondrial disorder precipitated by a virus infection.

==See also==
*[[Notable studies]]
*[[Muscle fatigability]]
*[[Muscle weakness]]
*[[Muscle pain]]
*[[Muscle fasciculations]]
*[[Muscle twitches]]

==References==
<references>

</references>

[[Category:Tests]]

Muscle biopsy

2018-06-20T22:27:05Z

Beth:add ongoing study at NIH

{{Stub}}

A '''muscle biopsy''' is a clinical procedure to remove a sample of muscle for examination.

==In ME/CFS==
Ongoing. The [[NIH Post-Infectious ME/CFS Study]] is currently running a sub-study on the muscle biopsies of up to 40 patients who meet the [[Canadian Consensus Criteria]] for ME/CFS, 20 controls, and 20 post-lyme patients.

==In postviral fatigue syndrome==
1991. Mitochondrial abnormalities in the postviral fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/1792865

We have examined the muscle biopsies of 50 patients who had postviral fatigue syndrome (PFS) for from 1 to 17 years. We found mild to severe atrophy of type II fibres in 39 biopsies, with a mild to moderate excess of lipid. On ultrastructural examination, 35 of these specimens showed branching and fusion of mitochondrial cristae. Mitochondrial degeneration was obvious in 40 of the biopsies with swelling, vacuolation, myelin figures and secondary lysosomes. These abnormalities were in obvious contrast to control biopsies, where even mild changes were rarely detected. The findings described here provide the first evidence that PFS may be due to a mitochondrial disorder precipitated by a virus infection.

==See also==
*[[Notable studies]]
*[[Muscle fatigability]]
*[[Muscle weakness]]
*[[Muscle pain]]
*[[Muscle fasciculations]]
*[[Muscle twitches]]

==References==
<references>

</references>

[[Category:Tests]]

Muscle biopsy

2018-06-20T04:25:40Z

Beth:just starting out

PAGE STUB

TODO: Intro to Muscle biopsies

[[Notable Studies]]

1991. Mitochondrial abnormalities in the postviral fatigue syndrome.
http://www.ncbi.nlm.nih.gov/pubmed/1792865

We have examined the muscle biopsies of 50 patients who had postviral fatigue syndrome (PFS) for from 1 to 17 years. We found mild to severe atrophy of type II fibres in 39 biopsies, with a mild to moderate excess of lipid. On ultrastructural examination, 35 of these specimens showed branching and fusion of mitochondrial cristae. Mitochondrial degeneration was obvious in 40 of the biopsies with swelling, vacuolation, myelin figures and secondary lysosomes. These abnormalities were in obvious contrast to control biopsies, where even mild changes were rarely detected. The findings described here provide the first evidence that PFS may be due to a mitochondrial disorder precipitated by a virus infection.

Marcie Zinn

2018-06-03T01:54:35Z

Beth:/* Notable studies */ removed conference paper now from notable studies now that full paper has been published.

[[File:Marcie Zinn.png|200px|thumb|right]]
'''Marcie L. Zinn''', Ph.D., is an experimental / clinical / rehabilitation psychologist conducting [[myalgic encephalomyelitis]] (ME) research with her husband, [[Mark Zinn]], and Dr. [[Leonard Jason]] at the DePaul Center for Community Research. Marcie's research interests include the study of brain dysfunction in chronic disease, such as [[myalgic encephalomyelitis]]. Marcie and her husband, Mark founded Performing Arts Neuroscience and Psychology. Her early research and career interests were in Performance Neuroscience and Psychology, but after being diagnosed in 2009 with viral encephalitis which developed into [[Myalgic Encephalomyelitis]], her interest turned toward using her extensive [[QEEG|qEEG]] and neuroscience skills for research in [[ME]]. Under the leadership of Dr. [[Jose Montoya]], she conducted a pilot study to look at cognitive dysfunction using [[QEEG|qEEG]] methods. While continuing to collaborate with Jose Montoya at Stanford, she and her husband [[Mark Zinn|Mark]] moved to Chicago to work with Dr. [[Leonard Jason]] and have published research using brain network modeling in the study of [[ME]] [[brain]] dysfunction.

==Open Letter to ''The Lancet''==
Two [[open letter to the Lancet|open letters to the editor of ''The Lancet'']] urged the editor to commission a fully independent review of the [[PACE]] trial, which the journal had published in 2011. In 2016, Dr. Zinn, along with 41 colleagues in the [[ME/CFS]] field, signed the second letter.

*10 February 2016, [http://www.virology.ws/2016/02/10/open-letter-lancet-again/ An open letter to The Lancet, again - Virology blog]

==Notable studies==

*2018 - Cortical hypoactivation during resting EEG suggests central nervous system pathology in patients with chronic fatigue syndrome. [https://www.sciencedirect.com/science/article/pii/S0301051118304071 (Abstract, full text on request)]
*2016 - Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with [[Myalgic Encephalomyelitis]]: A Pilot Study<ref name="Zinn, 2016" /> [https://www.researchgate.net/publication/294258397_Intrinsic_Functional_Hypoconnectivity_in_Core_Neurocognitive_Networks_Suggests_Central_Nervous_System_Pathology_in_Patients_with_Myalgic_Encephalomyelitis_A_Pilot_Study (Full Text)]
*2016 - [QEEG|qEEG]] / LORETA in Assessment of Neurocognitive Impairment in a Patient with [[Chronic Fatigue Syndrome]]: A Case Report<ref name="Zinn ML, 2016" /> [https://sciforschenonline.org/journals/clinical-research/CLROA-2-110.php (Full Text)]
*2016 - Functional Neural Network Connectivity in [[Myalgic Encephalomyelitis]]<ref name="Zinn&Zinn, 2016" /> [https://www.researchgate.net/publication/297453164_NeuroRegulation_httpwwwisnrorg_Functional_Neural_Network_Connectivity_in_Myalgic_Encephalomyelitis (Full Text)]
*2015 - [[Myalgic Encephalomyelitis]]: Symptoms and [[Biomarker]]s<ref name="Jason,Zinn, 2015" /> [http://www.ncbi.nlm.nih.gov/pubmed/26411464 (Full Text)]
*2014, Conference paper, EEG peak alpha frequency is associated with [[chronic fatigue syndrome]]: A case-control observational study<ref name="Zinn, 2014" /> [https://www.researchgate.net/publication/267867139_EEG_peak_alpha_frequency_is_associated_with_chronic_fatigue_syndrome_A_case-control_observational_study (Full Text)]

==Talks & interviews==

*2016 - [https://www.youtube.com/watch?v=aN0Fh0kiUiI "qEEG LORETA CFS Case study - Sci Forschen Inc."] with Leonard Jason, Marcie Zinn, and Mark Zinn

==Online presence==

*[https://www.ncbi.nlm.nih.gov/pubmed/?term=Zinn%20ML%5BAuthor%5D&cauthor=true&cauthor_uid=26869373 PubMed]
*[https://www.researchgate.net/profile/Dr_Marcie_Zinn ResearchGate]
*[https://www.linkedin.com/in/marcie-zinn-795083a8/ LinkedIn]

==Learn more==

*[http://www.selfgrowth.com/experts/marcie_zinn.html "Marcie Zinn Ph.D., NCTM" bio]

==See also==

*[[Mark Zinn]]
*[[Leonard Jason]]
*[[qEEG]]

==References==
<references>
<ref name="Zinn, 2014">{{Citation
| last1 = Zinn | first1 = Marcie L | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark A | authorlink2 = Mark Zinn
| last3 = Norris | first3 = Jane | authorlink3 = Jane Norris
| last4 = Valencia | first4 = Ian | authorlink4 =
| last5 = Montoya | first5 = Jose G | authorlink5 = Jose Montoya
| last6 = Maldonad | first6 = Jose R | authorlink6 =
| title = EEG peak alpha frequency is associated with chronic fatigue syndrome: A case-control observational study
| journal = Conference: 2014 Stanford Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Symposium | volume = | issue = | page =
| date = 2014
| url = https://www.researchgate.net/publication/267867139_EEG_peak_alpha_frequency_is_associated_with_chronic_fatigue_syndrome_A_case-control_observational_study
}}
</ref>
<ref name="Zinn, 2016">{{Citation
| last1 = Zinn | first1 = Marcie | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark | authorlink2 = Mark Zinn
| last3 = Jason | first3 = Leonard | authorlink3 = Leonard Jason
| title = Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study
| journal = Applied Psychophysiology and Biofeedback | volume = 41 | issue = 3 | page = 283-300
| date = 2016
| pmid = 26869373
| doi = 10.1007/s10484-016-9331-3
}}
</ref>
<ref name="Zinn ML, 2016">{{Citation
| last1 = Zinn | first1 = Marcie | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark | authorlink2 = Mark Zinn
| last3 = Jason | first3 = Leonard | authorlink3 = Leonard Jason
| title = qEEG / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report
| journal = Clinical Research: Open Access | volume = 2 | issue = 1 | page =
| date = 2016
| pmid = 26869373
| doi = 10.16966/2469-6714.110
}}
</ref>
<ref name="Zinn&Zinn, 2016">{{Citation
| last1 = Zinn | first1 = Marcie | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark | authorlink2 = Mark Zinn
| last3 = Jason | first3 = Leonard | authorlink3 = Leonard Jason
| title = Functional Neural Network Connectivity in Myalgic Encephalomyelitis
| journal = NeuroRegulation | volume = 3 | issue = 1 | page = 28-50
| date = 2016
| pmid =
| doi = 10.15540/nr.3.1.28
}}
</ref>
<ref name="Jason,Zinn, 2015">{{Citation
| last1 = Jason | first1 = Leonard | authorlink1 = Leonard Jason
| last2 = Zinn | first2 = Marcie | authorlink2 = Marcie Zinn
| last3 = Zinn | first3 = Mark | authorlink3 = Mark Zinn
| title = Myalgic Encephalomyelitis: Symptoms and Biomarkers
| journal = Current Neuropharmacology | volume = 13 | issue = 5 | page = 701-34.
| date = 2015
| pmid = 26411464
| doi = 10.2174/1570159X13666150928105725
}}
</ref>
</references>

[[Category:Researchers]]
[[Category:USA researchers]]
[[Category:People with ME, CFS, and/or FMS]]
[[Category:Psychological paradigm critics]]
[[Category:PACE trial critics]]

Marcie Zinn

2018-06-03T01:47:03Z

Beth:/* Notable studies */ Added new study

[[File:Marcie Zinn.png|200px|thumb|right]]
'''Marcie L. Zinn''', Ph.D., is an experimental / clinical / rehabilitation psychologist conducting [[myalgic encephalomyelitis]] (ME) research with her husband, [[Mark Zinn]], and Dr. [[Leonard Jason]] at the DePaul Center for Community Research. Marcie's research interests include the study of brain dysfunction in chronic disease, such as [[myalgic encephalomyelitis]]. Marcie and her husband, Mark founded Performing Arts Neuroscience and Psychology. Her early research and career interests were in Performance Neuroscience and Psychology, but after being diagnosed in 2009 with viral encephalitis which developed into [[Myalgic Encephalomyelitis]], her interest turned toward using her extensive [[QEEG|qEEG]] and neuroscience skills for research in [[ME]]. Under the leadership of Dr. [[Jose Montoya]], she conducted a pilot study to look at cognitive dysfunction using [[QEEG|qEEG]] methods. While continuing to collaborate with Jose Montoya at Stanford, she and her husband [[Mark Zinn|Mark]] moved to Chicago to work with Dr. [[Leonard Jason]] and have published research using brain network modeling in the study of [[ME]] [[brain]] dysfunction.

==Open Letter to ''The Lancet''==
Two [[open letter to the Lancet|open letters to the editor of ''The Lancet'']] urged the editor to commission a fully independent review of the [[PACE]] trial, which the journal had published in 2011. In 2016, Dr. Zinn, along with 41 colleagues in the [[ME/CFS]] field, signed the second letter.

*10 February 2016, [http://www.virology.ws/2016/02/10/open-letter-lancet-again/ An open letter to The Lancet, again - Virology blog]

==Notable studies==

*2018 - Cortical hypoactivation during resting EEG suggests central nervous system pathology in patients with chronic fatigue syndrome. [https://www.sciencedirect.com/science/article/pii/S0301051118304071 (Abstract, full text on request)]
*2016 - Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with [[Myalgic Encephalomyelitis]]: A Pilot Study<ref name="Zinn, 2016" /> [https://www.researchgate.net/publication/294258397_Intrinsic_Functional_Hypoconnectivity_in_Core_Neurocognitive_Networks_Suggests_Central_Nervous_System_Pathology_in_Patients_with_Myalgic_Encephalomyelitis_A_Pilot_Study (Full Text)]
*2016 - [QEEG|qEEG]] / LORETA in Assessment of Neurocognitive Impairment in a Patient with [[Chronic Fatigue Syndrome]]: A Case Report<ref name="Zinn ML, 2016" /> [https://sciforschenonline.org/journals/clinical-research/CLROA-2-110.php (Full Text)]
*2016 - Functional Neural Network Connectivity in [[Myalgic Encephalomyelitis]]<ref name="Zinn&Zinn, 2016" /> [https://www.researchgate.net/publication/297453164_NeuroRegulation_httpwwwisnrorg_Functional_Neural_Network_Connectivity_in_Myalgic_Encephalomyelitis (Full Text)]
*2015 - [[Myalgic Encephalomyelitis]]: Symptoms and [[Biomarker]]s<ref name="Jason,Zinn, 2015" /> [http://www.ncbi.nlm.nih.gov/pubmed/26411464 (Full Text)]
*2014, Conference paper, EEG peak alpha frequency is associated with [[chronic fatigue syndrome]]: A case-control observational study<ref name="Zinn, 2014" /> [https://www.researchgate.net/publication/267867139_EEG_peak_alpha_frequency_is_associated_with_chronic_fatigue_syndrome_A_case-control_observational_study (Full Text)]
*2014, Cortical hypoactivation during resting eLORETA suggests central nervous system pathology in patients with [[chronic fatigue syndrome]]<ref>Zinn, Mark & Zinn, Marcie & L. Norris, Jane & Valencia, Ian & Montoya, Jose & R. Maldonado, J. (2014). Cortical hypoactivation during resting eLORETA suggests central nervous system pathology in patients with chronic fatigue syndrome.</ref> [https://www.researchgate.net/publication/290628295_Cortical_hypoactivation_during_resting_eLORETA_suggests_central_nervous_system_pathology_in_patients_with_chronic_fatigue_syndrome (Abstract, full text on request)]

==Talks & interviews==

*2016 - [https://www.youtube.com/watch?v=aN0Fh0kiUiI "qEEG LORETA CFS Case study - Sci Forschen Inc."] with Leonard Jason, Marcie Zinn, and Mark Zinn

==Online presence==

*[https://www.ncbi.nlm.nih.gov/pubmed/?term=Zinn%20ML%5BAuthor%5D&cauthor=true&cauthor_uid=26869373 PubMed]
*[https://www.researchgate.net/profile/Dr_Marcie_Zinn ResearchGate]
*[https://www.linkedin.com/in/marcie-zinn-795083a8/ LinkedIn]

==Learn more==

*[http://www.selfgrowth.com/experts/marcie_zinn.html "Marcie Zinn Ph.D., NCTM" bio]

==See also==

*[[Mark Zinn]]
*[[Leonard Jason]]
*[[qEEG]]

==References==
<references>
<ref name="Zinn, 2014">{{Citation
| last1 = Zinn | first1 = Marcie L | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark A | authorlink2 = Mark Zinn
| last3 = Norris | first3 = Jane | authorlink3 = Jane Norris
| last4 = Valencia | first4 = Ian | authorlink4 =
| last5 = Montoya | first5 = Jose G | authorlink5 = Jose Montoya
| last6 = Maldonad | first6 = Jose R | authorlink6 =
| title = EEG peak alpha frequency is associated with chronic fatigue syndrome: A case-control observational study
| journal = Conference: 2014 Stanford Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Symposium | volume = | issue = | page =
| date = 2014
| url = https://www.researchgate.net/publication/267867139_EEG_peak_alpha_frequency_is_associated_with_chronic_fatigue_syndrome_A_case-control_observational_study
}}
</ref>
<ref name="Zinn, 2016">{{Citation
| last1 = Zinn | first1 = Marcie | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark | authorlink2 = Mark Zinn
| last3 = Jason | first3 = Leonard | authorlink3 = Leonard Jason
| title = Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study
| journal = Applied Psychophysiology and Biofeedback | volume = 41 | issue = 3 | page = 283-300
| date = 2016
| pmid = 26869373
| doi = 10.1007/s10484-016-9331-3
}}
</ref>
<ref name="Zinn ML, 2016">{{Citation
| last1 = Zinn | first1 = Marcie | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark | authorlink2 = Mark Zinn
| last3 = Jason | first3 = Leonard | authorlink3 = Leonard Jason
| title = qEEG / LORETA in Assessment of Neurocognitive Impairment in a Patient with Chronic Fatigue Syndrome: A Case Report
| journal = Clinical Research: Open Access | volume = 2 | issue = 1 | page =
| date = 2016
| pmid = 26869373
| doi = 10.16966/2469-6714.110
}}
</ref>
<ref name="Zinn&Zinn, 2016">{{Citation
| last1 = Zinn | first1 = Marcie | authorlink1 = Marcie Zinn
| last2 = Zinn | first2 = Mark | authorlink2 = Mark Zinn
| last3 = Jason | first3 = Leonard | authorlink3 = Leonard Jason
| title = Functional Neural Network Connectivity in Myalgic Encephalomyelitis
| journal = NeuroRegulation | volume = 3 | issue = 1 | page = 28-50
| date = 2016
| pmid =
| doi = 10.15540/nr.3.1.28
}}
</ref>
<ref name="Jason,Zinn, 2015">{{Citation
| last1 = Jason | first1 = Leonard | authorlink1 = Leonard Jason
| last2 = Zinn | first2 = Marcie | authorlink2 = Marcie Zinn
| last3 = Zinn | first3 = Mark | authorlink3 = Mark Zinn
| title = Myalgic Encephalomyelitis: Symptoms and Biomarkers
| journal = Current Neuropharmacology | volume = 13 | issue = 5 | page = 701-34.
| date = 2015
| pmid = 26411464
| doi = 10.2174/1570159X13666150928105725
}}
</ref>
</references>

[[Category:Researchers]]
[[Category:USA researchers]]
[[Category:People with ME, CFS, and/or FMS]]
[[Category:Psychological paradigm critics]]
[[Category:PACE trial critics]]

OMF's Repository

2018-05-20T23:14:01Z

Beth:early entry for OMF's data sharing policy

* Data from the Severely Ill study is open to all vetted researchers
* Any researcher funded by OMF has to share their data with one another.

Category:Biobanks & patient registries

2018-05-20T22:51:49Z

Beth:/* Please create pages in this category for */ adding OMF page

== Please create pages in this category for ==

*[[OMI OpenMedNet]]
*[[OMF's Repository]]
*[[CFI CFS BioBank]]
*[[Simmaron Research BioBank]]

Category:Biobanks & patient registries

2018-05-20T22:51:17Z

Beth:/* Please create pages in this category for */ Adding OMF

== Please create pages in this category for ==

*[[OMI OpenMedNet]]
*OMF's Repository
*[[CFI CFS BioBank]]
*[[Simmaron Research BioBank]]

Howard Bloom

2018-01-29T00:43:42Z

Beth:/* Talks & interviews */ minor

[[File:Howard Bloom.png|upright|right|en.wikipedia.org]]
'''Howard K. Bloom''' (born June 25, 1943) is an American author and music publicist. Prior to developing [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] (ME/CFS) in 1988, he had been the publicist for some of the biggest names in popular music in the 1970s and 1980s. These included Prince, Billy Joel, Styx, Michael Jackson, Cyndi Lauper, Talking Heads, Lionel Richie, ZZ Top, Bette Midler, AC/DC, Simon & Garfunkel, John Mellencamp, Earth, Wind & Fire, and Kiss.<ref>https://en.wikipedia.org/wiki/Howard_Bloom</ref>

After getting [[ME/CFS]] in 1988, he became bedbound for five years and housebound after that. Being unable to continue working as a publicist, he began to write books on history, science and religion. His titles include ''The Lucifer Principle: A Scientific Expedition into the Forces of History'', ''The God Problem: How a Godless Cosmos Creates'', ''How I Accidentally Started the Sixties'', and ''The Mohammad Code: How a Desert Prophet Brought You ISIS, al Qaeda, and Boko Haram''.<ref>http://www.amazon.com/Howard-Bloom/e/B001KIRZ9U/ref=dp_byline_cont_book_1</ref>

In 2001, Bloom fought the New York City Clerk's Office ruling that allowed them to refuse to issue him a marriage license in his home, despite being housebound. Marriage licenses can be arranged for others unable to attend its office, such as those confined to hospitals, nursing homes and prisons, but there was a union rule that prohibited City Clerk workers from going to people’s homes. One city employee suggested that Bloom take an ambulance to the clerk’s office, which he refused. He called his publicist, who, in turn, called the media. Soon, a personal visit was made by the city clerk to his house to issue a marriage license. Bloom stated that it was little comfort for him, because he wonders about the other housebound patients of CFS who don’t have the money and connections to maneuver bureaucratic rulings. “There are hundreds and thousands of people who are just like me,” Bloom said. “And they are voiceless.”<ref> http://nypost.com/2001/06/04/red-tape-gums-up-trip-down-aisle/</ref>

''The New York Times'' observed that the city's regulations in regard to obtaining marriage licenses at the city clerk's office were likely to be in breach of the Americans with Disabilities Act of 1990, as well as city and state human rights laws. Bloom stated: "There has to be a more visionary solution, ways to redo the bureaucratic system so people could do this online or on the telephone. New York City has to get its bureaucratic systems out of the age of Nikolai Gogol."<ref>http://www.nytimes.com/2001/06/11/nyregion/metro-matters-to-say-i-do-in-new-york-be-healthy.html</ref>

The 2007 edition ''Chronic Fatigue Syndrome For Dummies,'' by Susan R. Lisman M.D. and Karla Dougherty, includes Howard Bloom in the chapter on "Ten Famous People With CFS."<ref>https://www.amazon.com/dp/0470117729/ref=rdr_ext_tmb</ref>

Howard Bloom is one of the people living with [[ME/CFS]] interviewed for the documentary, ''[[Unrest]]'', by [[Jennifer Brea]].<ref>http://www.canaryinacoalminefilm.com/</ref>

==Articles==
*5 Jan 2018 - [https://www.nytimes.com/2018/01/05/nyregion/how-howard-bloom-writer-and-former-publicist-spends-his-sundays.html?_r=0 How Howard Bloom, Writer and Former Publicist, Spends His Sundays]

==Talks & interviews==
*2013, [https://www.youtube.com/watch?v=hyhlAPA-Rsc&feature=youtu.be Howard Bloom - On what happens when we extend ourselves]
*2013, [http://www.healtheo360.com/howardbloom Howard Bloom: Living Strong with Chronic Fatigue Syndrome (21 videos)]

==Books==
* 2016, ''The Mohammad Code: How a Desert Prophet Brought You ISIS, al Qaeda, and Boko Haram'', paperbook edition.<ref>Bloom, H.K. (2016)''The Mohammad Code: How a Desert Prophet Brought You ISIS, al Qaeda, and Boko Haram''. Port Townsend, WA: Feral House.</ref>
* 2014, ''How I Accidentally Started the Sixties''<ref>Bloom, H.K. (2014) ''How I Accidentally Started the Sixties''. Howard Bloom, CreateSpace Independent Publishing Platform.</ref>
* 2013, ''The Mohammed Code: Why a Desert Prophet Wants You Dead''<ref>Bloom, H.K. (2013). Howard Bloom, CreateSpace Independent Publishing Platform</ref>
* 2012, ''The God Problem: How a Godless Cosmos Creates''<ref>Bloom, H.K. (2012). ''The God Problem: How a Godless Cosmos Creates''. Amherst, N.Y.: Prometheus Books.</ref>
* 2010, ''The Genius of the Beast : A Radical Re-vision of Capitalism''<ref>Bloom, H.K. (2010). ''The Genius of the Beast : A Radical Re-vision of Capitalism''. Amherst, NY: Prometheus Books.</ref>
* 2000, ''The Global Brain: The Evolution of Mass Mind from the Big Bang to the 21st Century''<ref>Bloom, H.K. (2000) ''The Global Brain: The Evolution of Mass Mind from the Big Bang to the 21st Century''. New York, NY: Wiley.</ref>
* 1995, 1997, ''The Lucifer Principle : A Scientific Expedition into the Forces of History''<ref>Bloom, H.K. (1995, 1997). ''The Lucifer Principle : A Scientific Expedition into the Forces of History''. New York, NY: The Atlantic Monthly Press.</ref>

==Online presence==
*[https://twitter.com/HowardxBloom Twitter - Howard Bloom]
*[http://howardbloom.net/ Website]
*[https://www.youtube.com/user/howbloom YouTube - Howard Bloom]

==Learn more==
*[https://en.wikipedia.org/wiki/Howard_Bloom Wikipedia - Howard Bloom]

==See also==
*[[Unrest]]

==References==
<references>

</references>

[[Category:ME and CFS in popular culture]]
[[Category:People with ME, CFS, and/or FMS]]
[[Category:Famous people with ME, CFS, and/or FMS]]
[[Category:American famous people with ME, CFS, and/or FMS]]

Howard Bloom

2018-01-29T00:42:02Z

Beth:/* Talks & interviews */ added interview series to page

[[File:Howard Bloom.png|upright|right|en.wikipedia.org]]
'''Howard K. Bloom''' (born June 25, 1943) is an American author and music publicist. Prior to developing [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] (ME/CFS) in 1988, he had been the publicist for some of the biggest names in popular music in the 1970s and 1980s. These included Prince, Billy Joel, Styx, Michael Jackson, Cyndi Lauper, Talking Heads, Lionel Richie, ZZ Top, Bette Midler, AC/DC, Simon & Garfunkel, John Mellencamp, Earth, Wind & Fire, and Kiss.<ref>https://en.wikipedia.org/wiki/Howard_Bloom</ref>

After getting [[ME/CFS]] in 1988, he became bedbound for five years and housebound after that. Being unable to continue working as a publicist, he began to write books on history, science and religion. His titles include ''The Lucifer Principle: A Scientific Expedition into the Forces of History'', ''The God Problem: How a Godless Cosmos Creates'', ''How I Accidentally Started the Sixties'', and ''The Mohammad Code: How a Desert Prophet Brought You ISIS, al Qaeda, and Boko Haram''.<ref>http://www.amazon.com/Howard-Bloom/e/B001KIRZ9U/ref=dp_byline_cont_book_1</ref>

In 2001, Bloom fought the New York City Clerk's Office ruling that allowed them to refuse to issue him a marriage license in his home, despite being housebound. Marriage licenses can be arranged for others unable to attend its office, such as those confined to hospitals, nursing homes and prisons, but there was a union rule that prohibited City Clerk workers from going to people’s homes. One city employee suggested that Bloom take an ambulance to the clerk’s office, which he refused. He called his publicist, who, in turn, called the media. Soon, a personal visit was made by the city clerk to his house to issue a marriage license. Bloom stated that it was little comfort for him, because he wonders about the other housebound patients of CFS who don’t have the money and connections to maneuver bureaucratic rulings. “There are hundreds and thousands of people who are just like me,” Bloom said. “And they are voiceless.”<ref> http://nypost.com/2001/06/04/red-tape-gums-up-trip-down-aisle/</ref>

''The New York Times'' observed that the city's regulations in regard to obtaining marriage licenses at the city clerk's office were likely to be in breach of the Americans with Disabilities Act of 1990, as well as city and state human rights laws. Bloom stated: "There has to be a more visionary solution, ways to redo the bureaucratic system so people could do this online or on the telephone. New York City has to get its bureaucratic systems out of the age of Nikolai Gogol."<ref>http://www.nytimes.com/2001/06/11/nyregion/metro-matters-to-say-i-do-in-new-york-be-healthy.html</ref>

The 2007 edition ''Chronic Fatigue Syndrome For Dummies,'' by Susan R. Lisman M.D. and Karla Dougherty, includes Howard Bloom in the chapter on "Ten Famous People With CFS."<ref>https://www.amazon.com/dp/0470117729/ref=rdr_ext_tmb</ref>

Howard Bloom is one of the people living with [[ME/CFS]] interviewed for the documentary, ''[[Unrest]]'', by [[Jennifer Brea]].<ref>http://www.canaryinacoalminefilm.com/</ref>

==Articles==
*5 Jan 2018 - [https://www.nytimes.com/2018/01/05/nyregion/how-howard-bloom-writer-and-former-publicist-spends-his-sundays.html?_r=0 How Howard Bloom, Writer and Former Publicist, Spends His Sundays]

==Talks & interviews==
*2013, [https://www.youtube.com/watch?v=hyhlAPA-Rsc&feature=youtu.be Howard Bloom - On what happens when we extend ourselves]
*2013, [http://www.healtheo360.com/howardbloom Howard Bloom: Living Strong with Chronic Fatigue Syndrome]

==Books==
* 2016, ''The Mohammad Code: How a Desert Prophet Brought You ISIS, al Qaeda, and Boko Haram'', paperbook edition.<ref>Bloom, H.K. (2016)''The Mohammad Code: How a Desert Prophet Brought You ISIS, al Qaeda, and Boko Haram''. Port Townsend, WA: Feral House.</ref>
* 2014, ''How I Accidentally Started the Sixties''<ref>Bloom, H.K. (2014) ''How I Accidentally Started the Sixties''. Howard Bloom, CreateSpace Independent Publishing Platform.</ref>
* 2013, ''The Mohammed Code: Why a Desert Prophet Wants You Dead''<ref>Bloom, H.K. (2013). Howard Bloom, CreateSpace Independent Publishing Platform</ref>
* 2012, ''The God Problem: How a Godless Cosmos Creates''<ref>Bloom, H.K. (2012). ''The God Problem: How a Godless Cosmos Creates''. Amherst, N.Y.: Prometheus Books.</ref>
* 2010, ''The Genius of the Beast : A Radical Re-vision of Capitalism''<ref>Bloom, H.K. (2010). ''The Genius of the Beast : A Radical Re-vision of Capitalism''. Amherst, NY: Prometheus Books.</ref>
* 2000, ''The Global Brain: The Evolution of Mass Mind from the Big Bang to the 21st Century''<ref>Bloom, H.K. (2000) ''The Global Brain: The Evolution of Mass Mind from the Big Bang to the 21st Century''. New York, NY: Wiley.</ref>
* 1995, 1997, ''The Lucifer Principle : A Scientific Expedition into the Forces of History''<ref>Bloom, H.K. (1995, 1997). ''The Lucifer Principle : A Scientific Expedition into the Forces of History''. New York, NY: The Atlantic Monthly Press.</ref>

==Online presence==
*[https://twitter.com/HowardxBloom Twitter - Howard Bloom]
*[http://howardbloom.net/ Website]
*[https://www.youtube.com/user/howbloom YouTube - Howard Bloom]

==Learn more==
*[https://en.wikipedia.org/wiki/Howard_Bloom Wikipedia - Howard Bloom]

==See also==
*[[Unrest]]

==References==
<references>

</references>

[[Category:ME and CFS in popular culture]]
[[Category:People with ME, CFS, and/or FMS]]
[[Category:Famous people with ME, CFS, and/or FMS]]
[[Category:American famous people with ME, CFS, and/or FMS]]

Richard Podell

2017-10-17T22:00:10Z

Beth:updated Podell's status (he retired)

[[File:Richard Podell.png|200px|thumb|right|Source:LinkedIn]]
'''Richard Podell''', M.D., MPH, is a Clinical Professor at Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey and has a private practice where he sees [[ME/CFS]], [[Fibromyalgia]] and other patients. He practiced integrated medicine in Summit, NJ but is retired as of September 1, 2017. He was a provider of [[Ampligen]] during one of its earlier trials.

In 2002, Podell was a member of the writing committee for [[A Consensus Manual for the Primary Care and Management of Chronic Fatigue Syndrome]], a clinical care manual produced by The Academy of Medicine of New Jersey and the New Jersey Department of Health and Senior Services.<ref>[http://www.nj.gov/health/fhs/documents/cfs_consensus_manual.pdf A Consensus Manual for the Primary Care and Management of Chronic Fatigue Syndrome - 2002 by The Academy of Medicine of New Jersey and the New Jersey Department of Health and Senior Services]</ref>

Dr. Podell provides updates in research and treatment options via his YouTube channel: [https://www.youtube.com/channel/UCUJQ6r1gItgzJI0TCIZmPiw ''Chronic Fatigue and Fibromyalgis Update with Dr. Richard Podell'']

==Education==
*M.D. - Harvard Medical School

==Clinic==
*Address: 11 Upper Overlook Rd # 140, Summit, NJ 07901
*Phone: (908) 273-7770

==Open Letter to ''The Lancet''==
Two [[open letter to the Lancet | open letters to the editor of ''The Lancet'']] urged the editor to commission a fully independent review of the [[PACE]] trial, which the journal had published in 2011. In 2016, Dr. Podell, along with 41 colleagues in the [[ME/CFS]] field, signed the second letter.
*10 February 2016, [http://www.virology.ws/2016/02/10/open-letter-lancet-again/ An open letter to The Lancet, again - Virology blog]

==Chronic Fatigue and Fibromyalgis Update with Dr. Richard Podell==
'''Ginevra Liptan'''
*[https://www.youtube.com/watch?v=_QHuJ13TTVs Ginevra Liptan - Segment 1: The Pros and Cons of medical Marijuana Use of Fibromyalgia Patients]
*[https://www.youtube.com/watch?v=m7a7g1rfqOg Ginevra Liptan - Segment 2: The Use of Medical Marijuana for Fibromyalgia Patients]

'''Kim Jones'''
*[https://www.youtube.com/watch?v=d3M9R0pc1jI Kim Jones - Segment 1: Exercise with Fibromyalgia]
*[https://www.youtube.com/watch?v=0S0VFcWAli4&feature=youtu.be Kim Jones - Segment 2: Exercise and Fibromyalgia]
*[https://www.youtube.com/watch?v=I97QLyUA1zU Kim Jones - Segment 3: Exercise and Fibromyalgia]

'''[[Alan Light]]'''
*[https://www.youtube.com/watch?v=ZZyXUL7CPks&feature=youtu.be Alan Light - Segment 1: Why Research Chronic Fatigue Syndrome and Fibromyalgia?]
*[https://www.youtube.com/watch?v=oyjuWwuKmFA Alan Light - Segment 2: Detailed Explanation of Dr. Light's CFS and FM Research]
*[https://www.youtube.com/watch?v=S3CmUJyVBbQ Alan Light - Segment 3: Update on Dr. Light's Recent CFS and FM Research]

==Notable studies==
*2017, Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study<blockquote>"Abstract - In the Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM), we relied on expert clinician diagnoses to enroll patients from 7 specialty clinics in the United States in order to perform a systematic collection of data on measures of myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS). Healthy persons and those with other illnesses that share some features with ME/CFS were enrolled in comparison groups. The major objectives were to: 1) use standardized questionnaires to measure illness domains of ME/CFS and to evaluate patient heterogeneity overall and between clinics; 2) describe the course of illness, identify the measures that best correlate with meaningful clinical differences, and assess the performances of questionnaires as patient/person-reported outcome measures; 3) describe prescribed medications, orders for laboratory and other tests, and management tools used by expert clinicians to care for persons with ME/CFS; 4) collect biospecimens for future hypothesis testing and for evaluation of morning cortisol profiles; and 5) identify measures that best distinguish persons with ME/CFS from those in the comparison groups and detect subgroups of persons with ME/CFS who may have different underlying causes. Enrollment began in 2012 and is planned to continue in multiple stages through 2017. We present the MCAM methods in detail, along with an initial description of the 471 patients with ME/CFS who were enrolled in stage 1."<ref name="Unger, 2017"/>

==Books==
*2002, Dr. Podell was on the writing committee for ''[[A Consensus Manual for the Primary Care and Management of Chronic Fatigue Syndrome]]'', Joseph F. John, Jr., MD, Editor and James M. Oleske, MD, MPH, Associate Editor.<ref>Oleske JJ. A Consensus Manual for the Primary Care and Management of Chronic Fatigue Syndrome. The Academy of Medicine of New Jersey, The New Jersey Department of Health & Senior Services; 2002.</ref>

== Online presence ==
*[http://www.drpodell.org/ Office Website]
*[https://www.facebook.com/dr.podell Facebook]
*[http://www.drpodell.org/blog/ Blog]
*[https://www.youtube.com/channel/UCUJQ6r1gItgzJI0TCIZmPiw YouTube Channel]
*[https://www.linkedin.com/in/richard-podell-15b4011b LinkedIn]

==References==
<references>
<ref name="Unger, 2017">
{{Citation
| last1 = Unger | first1 = Elizabeth R. | authorlink1 = Elizabeth Unger
| last2 = Lin | first2 = Jin-Mann S. | authorlink2 =
| last3 = Tian | first3 = Hao | authorlink3 =
| last4 = Natelson | first4 = Benjamin H | authorlink4 = Benjamin Natelson
| last5 = Lange | first5 = Gudrun | authorlink5 = Gudrun Lange
| last6 = Vu | first6 = Diana | authorlink6 =
| last7 = Blate | first7 = Michelle | authorlink7 =
| last8 = Klimas | first8 = Nancy G. | authorlink8 = Nancy Klimas
| last9 = Balbin | first9 = Elizabeth G. | authorlink9 =
| last10 = Bateman | first10 = Lucinda | authorlink10 = Lucinda Bateman
| last11 = Allen | first11 = Ali | authorlink11 =
| last12 = Lapp | first12 = Charles W. | authorlink12 = Charles Lapp
| last13 = Springs | first13 = Wendy | authorlink13 =
| last14 = Kogelnik | first14 = Andreas M. | authorlink14 = Andreas Kogelnik
| last15 = Phan | first15 = Catrina C. | authorlink15 =
| last16 = Danver | first16 = Joan | authorlink16 =
| last17 = Podell | first17 = Richard N. | authorlink17 = Richard Podell
| last18 = Fitzpatrick | first18 = Trisha | authorlink18 =
| last19 = Peterson | first19 = Daniel L. | authorlink19 = Daniel Peterson
| last20 = Gottschalk | first20 = C. Gunnar | authorlink20 = Gunnar Gottschalk
| last21 = Rajeevan | first21 = Mangalathu S. | authorlink21 =
| last22 = MCAM Study Group
| title = Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.
| journal = American Journal of Epidemiology | volume = 1-10 | issue = | page =
| date = 2017
| pmid =
| doi = 10.1093/aje/kwx029
}}
</ref>
</references>

[[Category:Clinicians]]
[[Category:American clinicians]]
[[Category:New Jersey clinicians]]
[[Category:Psychological paradigm critics]]
[[Category:PACE trial critics]]

United States proclamations and resolutions

2017-06-07T09:12:21Z

Beth:edited filename for Knoxville

A list of [[United States]] '''proclamations''', listed by state/province and city.

==Arizona==
*Phoenix, May 2016 [[Media:2016-05-12_Chronic_Fatigue_Syndrome_Final_Proclamation,_Phoenix_AZ_Mayor_Greg_Stanton.pdf|Proclamation by Mayor Stanton]] (pdf)

==California==
--State--
*California State Senate, May 18, 2017, adopted bill SCR-40 Myalgic Encephalomyelitis Awareness Month; [[Media:SCR 40.pdf| Bill introduced by Senator Steve Glazer and Assembly Member Catharine B. Baker]]; [https://www.youtube.com/watch?v=Wu4FVCT9YWU Video of bill vote]

--Cities & Counties--
*Anaheim, May 2015 [[Media:ANAHEIM CA USA PROCLAMATION by Mayor Tait, Council 2015-05-12 & Info.pdf|Proclamation by Mayor Tait & Council]] (pdf)
*Elk Grove, May 2016 [[Media: Elk Grove CA USA Mayor & Council 05-11-16 Proclamation.pdf|Proclamation by Mayor Davis & Council]] (pdf)
*Los Angeles, May 2016 [[Media:2016-05-12 Los Angeles ME-CFS Certificate Mayor Eric Garcetti.jpg|Proclamation by Mayor Garcetti]] (jpg)
*Pleasanton, May 2016 [[Media: 2016-05-12 Pleasanton CA Proclamation.pdf|Proclamation by Mayor Thorne & Council]] (pdf)
*Sacramento, May 2016 [[Media: Sacramento CA USA Recognizing May 12, 2016 as Myalgic Encephalomyelitis & Chronic Fatigue Syndrome Awareness Day Resolution, CRA2016-020.pdf|Proclamation by Mayor Johnson & Council]] (pdf)
*San Ramon, May 2016 [[Media: 2016,_May_12_ME_Proclamation_by_San_Ramon,_CA_USA_Mayor_Bill_Clarkson.pdf|Proclamation by Mayor Bill Clarkson]] (pdf)
*West Sacramento, May 2016 [[Media:2016-05-12 West Sacramento ME proclamation, Mayor Cabaldon.pdf|Proclamation by Mayor Cabaldon]] (pdf)
*San Francisco, Sep 27, 2016 [[Media:San Francisco Proclamation.jpg|Proclamation by Mayor Edwin Lee naming May 12, 2017 as SF ME/CFS Awareness Day]] (jpg)
*San Francisco, Sep 27, 2016 [[Media:Certificate of Honor, SF Board of Supervisors.jpg|Board of Supervisors Certificate of Honor honoring #MillionsMissing for advocacy work]] (jpg)

==Georgia==
*State of Georgia, May 2017 [http://www.legis.ga.gov/Legislation/20172018/164298.pdf Georgia House Resolution] (pdf)

==Illinois==
*State of Illinois, May 2017 [http://www.ilga.gov/legislation/100/HR/10000HR0021.htm Illinois House Resolution] (htm)

==Michigan==
*Grand Rapids, May 2012 [[Media: GRAND RAPIDS & West MI USAProclamation, Mayor Hartwell 2012-05.jpg|Proclamation for Grand Rapids, MI]] (jpg)

==Maryland==
*Montgomery County, Sep 27 2016 [[Media:Maryland proclamation montgomery county.JPG|Proclamation for Montgomery County]] (jpg)

==Massachusetts==
*State of Massachusetts, May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOya0JHT20xUEdIV2M/view Proclamation for Massachusetts] (jpg)
*Northampton, MA, Oct 2016 [https://drive.google.com/file/d/0B3fv5Vz5YsOyTTQ0ZE12SWdXdzQ/view Proclamation for Northampton, MA] (jpg)
*Pittsfield, MA, May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOybTR1Q0JhOFFLVEE/view Proclamation for Pittsfield, MA] (pdf)
*Cambridge, MA, May 2017 [http://me-pedia.org/images/4/44/CityofCambridge_MECFS_Proclamation_2017.jpg Proclamation for Cambridge, MA] (jpg)

==New Jersey==
*State of New Jersey, May 2017 [http://www.njmecfsa.org/wp-content/uploads/2017/04/Proclamation-2017.jpg Proclamation for New Jersey] (jpg)

==North Carolina==
*State of North Carolina, May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOyTTVaUzZGUGFwbms/view Proclamation for North Carolina] (jpg)
*Washington, NC May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOyMFFMM3lnWGsyYXM/view Proclamation for Washington, NC] (jpg)

==Ohio==
*Springfield, OH, May 2015 [https://drive.google.com/file/d/0B3fv5Vz5YsOyYm5fSDJTTjB2amc/view Proclamation for Springfield] (jpg)

==Tennessee==
*Knoxville, TN, May 2017 [[Media:Knoxville_Mayoral_Proclamation_ME_CFS_Awareness_Day_May_12%2C_2017-Proclamation_by_Mayor_Rogero.pdf|Proclamation by Mayor Rogero]] (pdf)

==Texas==
*Houston, TX, May 2016 [[Media:Proclamation Houston Mayor 2016-05.pdf|Proclamation by Mayor Turner]] (pdf)

==See also==
*[[Illuminated landmarks]]
*[[:Category:Open letters|Open letters]]

[[Category:Advocacy and fundraising initiatives]]

File:Knoxville Mayoral Proclamation ME CFS Awareness Day May 12, 2017-Proclamation by Mayor Rogero.pdf

2017-06-07T09:10:08Z

Beth:May 2017 Knoxville, Tennessee Mayoral Proclamation for ME/CFS Awareness Day

May 2017 Knoxville, Tennessee Mayoral Proclamation for ME/CFS Awareness Day

United States proclamations and resolutions

2017-06-07T09:08:28Z

Beth:added in Knoxville

A list of [[United States]] '''proclamations''', listed by state/province and city.

==Arizona==
*Phoenix, May 2016 [[Media:2016-05-12_Chronic_Fatigue_Syndrome_Final_Proclamation,_Phoenix_AZ_Mayor_Greg_Stanton.pdf|Proclamation by Mayor Stanton]] (pdf)

==California==
--State--
*California State Senate, May 18, 2017, adopted bill SCR-40 Myalgic Encephalomyelitis Awareness Month; [[Media:SCR 40.pdf| Bill introduced by Senator Steve Glazer and Assembly Member Catharine B. Baker]]; [https://www.youtube.com/watch?v=Wu4FVCT9YWU Video of bill vote]

--Cities & Counties--
*Anaheim, May 2015 [[Media:ANAHEIM CA USA PROCLAMATION by Mayor Tait, Council 2015-05-12 & Info.pdf|Proclamation by Mayor Tait & Council]] (pdf)
*Elk Grove, May 2016 [[Media: Elk Grove CA USA Mayor & Council 05-11-16 Proclamation.pdf|Proclamation by Mayor Davis & Council]] (pdf)
*Los Angeles, May 2016 [[Media:2016-05-12 Los Angeles ME-CFS Certificate Mayor Eric Garcetti.jpg|Proclamation by Mayor Garcetti]] (jpg)
*Pleasanton, May 2016 [[Media: 2016-05-12 Pleasanton CA Proclamation.pdf|Proclamation by Mayor Thorne & Council]] (pdf)
*Sacramento, May 2016 [[Media: Sacramento CA USA Recognizing May 12, 2016 as Myalgic Encephalomyelitis & Chronic Fatigue Syndrome Awareness Day Resolution, CRA2016-020.pdf|Proclamation by Mayor Johnson & Council]] (pdf)
*San Ramon, May 2016 [[Media: 2016,_May_12_ME_Proclamation_by_San_Ramon,_CA_USA_Mayor_Bill_Clarkson.pdf|Proclamation by Mayor Bill Clarkson]] (pdf)
*West Sacramento, May 2016 [[Media:2016-05-12 West Sacramento ME proclamation, Mayor Cabaldon.pdf|Proclamation by Mayor Cabaldon]] (pdf)
*San Francisco, Sep 27, 2016 [[Media:San Francisco Proclamation.jpg|Proclamation by Mayor Edwin Lee naming May 12, 2017 as SF ME/CFS Awareness Day]] (jpg)
*San Francisco, Sep 27, 2016 [[Media:Certificate of Honor, SF Board of Supervisors.jpg|Board of Supervisors Certificate of Honor honoring #MillionsMissing for advocacy work]] (jpg)

==Georgia==
*State of Georgia, May 2017 [http://www.legis.ga.gov/Legislation/20172018/164298.pdf Georgia House Resolution] (pdf)

==Illinois==
*State of Illinois, May 2017 [http://www.ilga.gov/legislation/100/HR/10000HR0021.htm Illinois House Resolution] (htm)

==Michigan==
*Grand Rapids, May 2012 [[Media: GRAND RAPIDS & West MI USAProclamation, Mayor Hartwell 2012-05.jpg|Proclamation for Grand Rapids, MI]] (jpg)

==Maryland==
*Montgomery County, Sep 27 2016 [[Media:Maryland proclamation montgomery county.JPG|Proclamation for Montgomery County]] (jpg)

==Massachusetts==
*State of Massachusetts, May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOya0JHT20xUEdIV2M/view Proclamation for Massachusetts] (jpg)
*Northampton, MA, Oct 2016 [https://drive.google.com/file/d/0B3fv5Vz5YsOyTTQ0ZE12SWdXdzQ/view Proclamation for Northampton, MA] (jpg)
*Pittsfield, MA, May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOybTR1Q0JhOFFLVEE/view Proclamation for Pittsfield, MA] (pdf)
*Cambridge, MA, May 2017 [http://me-pedia.org/images/4/44/CityofCambridge_MECFS_Proclamation_2017.jpg Proclamation for Cambridge, MA] (jpg)

==New Jersey==
*State of New Jersey, May 2017 [http://www.njmecfsa.org/wp-content/uploads/2017/04/Proclamation-2017.jpg Proclamation for New Jersey] (jpg)

==North Carolina==
*State of North Carolina, May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOyTTVaUzZGUGFwbms/view Proclamation for North Carolina] (jpg)
*Washington, NC May 2017 [https://drive.google.com/file/d/0B3fv5Vz5YsOyMFFMM3lnWGsyYXM/view Proclamation for Washington, NC] (jpg)

==Ohio==
*Springfield, OH, May 2015 [https://drive.google.com/file/d/0B3fv5Vz5YsOyYm5fSDJTTjB2amc/view Proclamation for Springfield] (jpg)

==Tennessee==
*Knoxville, TN, May 2017 [[Media:Knoxville, Tennessee Mayoral Proclamation ME_CFS Awareness Day May 12, 2017:Proclamation by Mayor Rogero]] (pdf)

==Texas==
*Houston, TX, May 2016 [[Media:Proclamation Houston Mayor 2016-05.pdf|Proclamation by Mayor Turner]] (pdf)

==See also==
*[[Illuminated landmarks]]
*[[:Category:Open letters|Open letters]]

[[Category:Advocacy and fundraising initiatives]]

MEpedia:Contents

2016-04-05T03:01:08Z

Beth:/* Research */ fixed markup

We are crowd-sourcing a knowledge base on the history, science and medicine of ME and CFS around the world. MEpedia is a patient community project being built by patients, founded by #[[MEAction]]. Read more [[MEpedia:About|about MEpedia and its principles]].

Want to take a look around? See our most [[Special:PopularPages|popular pages]], check our [[Special:NewPages|newest pages]], or visit a [[Special:random|random page]]. You can also browse a [[Special:AllPages|list of all pages]].

==Please contribute==
Anyone can create pages, write content, add links/citations, fact-check, or even just fix typos. Get involved and help the patient community identify all of the best and most important resources for our disease and its research, treatment and history. Start now, read [[How to contribute]]. Please join the MEpedia [http://my.meaction.net/local_chapters/mepedia online forum], [https://www.facebook.com/mepedia/ Facebook group], and follow us on [https://twitter.com/MEencyclopedia Twitter].

==Five minute tasks==

Only have a five minute spoon to give? Here is a [[List of small tasks|list of small tasks]] you can help us with in roughly one to ten minutes of time.

==Priority pages for expansion==

'''Science:''' [[Citric acid cycle]], [[Mitochondria]], [[Exercise]], [[Ampligen]], [[Natural killer cell]], [[Central nervous system]], [[Nitric oxide hypothesis]], [[Brain]], [[Brain imaging]]

'''History and politics:'''

==A note on ME v. CFS==

We have separate pages for [[Myalgic Encephalomyelitis]], [[ME/CFS]] and [[Chronic Fatigue Syndrome]] as well as [[SEID]]. The convention is that the terminology used in an ME-pedia article should match the terminology used in the underlying source. Where there is a tension between the term used in the source and the definition (e.g., [[ME]] defined by the [[Oxford criteria]] or [[CFS]] defined by the [[Canadian Consensus Criteria]]), it may be useful for clarity to mention the definition used.

==Primers==
*[[Primer for doctors and researchers]]
*[[Primer for patients]]
*[[Primer for science journalists]]
*[[Primer for the public]]
*[[Primer for family, friends and care providers]]

==The Disease==

'''Infectious agents:''' [[Borrelia]], [[Babesia]], [[Bartonella]], [[Borna Disease Virus]], [[Chlamydia pneumoniae]], [[Coxsackie A]], [[Coxsackie B]], [[cytomegalovirus]], [[Ebola virus]], [[echovirus]], [[enterovirus]], [[Epstein-Barr virus]], [[H1N1]], [[Herpesvirus]], [[HHV-6]], [[HHV-7]], [[HSV-1]], [[HSV-2]], [[influenza]], [[parvovirus B19]], [[Q Fever]], [[Ross River Virus]], [[Chlamydia Pneumonia]], [[Mycoplasma Pneumonia]], [[streptococcus]], [[fungal infection]]

'''Triggers and risk factors:''' [[Blood donation]], [[Candidiasis]], [[Causes of death]], [[Epidemiology]], [[Genetics]], [[Menstrual cycle]], [[Mold]], [[Pediatric]], [[Pregnancy]], [[Stress]], [[Toxic exposure]], [[Trauma]], [[Vaccine]], [[Viral onset]], [[bacterial disease onset]], [[fungal disease onset]]

'''Signs and symptoms:''' [[Ataxia]], [[attention deficits]], [[auditory sequencing problems]], [[balance problems]], [[Cognitive dysfunction]], [[Chronic pain]], [[Chronic fatigue]], [[concentration problems]], [[difficulty comprehending social cues]], [[dyslexia]], [[executive function problems]], [[Fatigue]], [[Food intolerance]], [[Irritable bowel syndrome]], [[low motivation]], [[Migraine Syndrome]], [[multi-tasking problems]], [[Muscle fatigability]], [[Neurally mediated hypotension]], [[Nonepileptic seizure]], [[Optical dysfunction]], [[Orientation in Space problems]], [[Orthostatic intolerance]], [[Planning problems]], [[Post-exertional malaise]], [[Postural orthostatic tachycardia]], [[Receptive language problems]], [[Seizure]], [[Sleep disturbance]], [[Slowed thought]], [[Unrefreshing sleep]], [[Word-finding problems]]

'''Medical hypotheses:''' [[Amygdala hypothesis]], [[Autoimmune hypothesis]], [[encephalitis]], [[autoimmune encephalitis]], [[Fatty acid hypothesis]], [[Hygiene hypothesis]], [[Immune exhaustion hypothesis]], [[Infectious disease hypothesis]], [[Ken Lassesen's model]], [[Methylation cycle hypothesis]], [[Microbiome hypothesis]], [[Mold hypothesis]], [[Patricia Kane protocol]], [[Vagus nerve hypothesis]], [[Viral onset hypothesis]] [[Hypercoagulation hypothesis]] [[Acquired immune and mitochondrial dysfunction hypothesis]]

'''Body systems:''' [[Antibody]], [[Autoantibody]], [[Blood]], [[Brain]], [[B cell]], [[Central sensitization]], [[Cytokine]], [[Chemokine]], [[Cardiovascular system]], [[Gastrointestinal system]], [[Glutamate excitotoxicity]], [[HPA axis]], [[Immune system]], [[IL-1]], [[IL-2]], [[IL-6]], [[IL-8]], [[IL-10]], [[IL-16]], [[IL-17]], [[IL-18]], [[interferon]], [[Leaky brain]], [[Leaky gut]], [[Macrophage]], [[Microglia]], [[Microbiome]], [[Mucosal immune system]], [[Nervous system]], [[Natural killer cell]], [[Neuroinflammation]], [[Ribonuclease L]], [[Spinal cord]], [[Tumor necrosis factors]], [[VEGF]], [[T cell]]

'''Tests:''' [[Brain imaging]], [[Cardiopulmonary exercise test]], [[CellTrend diagnostic test]], [[C reactive protein]], [[qEEG/LORETA]], [[Erythrocyte sedimentation rate]], [[Exercise]], [[National Centre for Neuroimmunology and Emerging Diseases#Potential biomarker|NCNED Griffith University diagnostic test]], [[MRI]], [[Orosomucoid]], [[qEEG]], [[SF-36]], [[SPECT]], [[Tilt Table]], [[Two day exercise test]], [[Natural Killer Cell (NKC) Function]], [[arginine vasopressin]], [[MTHFR and other methylation mutations]], [[infectious disesases]]

'''Citizen science:''' [[23andMe]], [[American Gut]], [[Any Treatment]], [[Mendus]], [[Phoenix Rising]], [[UBiome]], [[Know Your Genetics: Dr. Amy Yasko]], [[WellnessFX]], [[CH3Nutrigenomics; Dr. Amy Yasko]], [[MTHFR.net]], [[Genetic Genie]], [[LiveWello]]

'''Biochemistry and cell biology:''' [[ATP]], [[Cellular respiration]], [[Citric acid cycle]], [[D lactate]], [[Endocannabinoid]], [[Glucocorticoid]], [[Glutathione]], [[Histamine]], [[Methylation cycle]], [[Mitochondria]], [[Nitric oxide]], [[Oxidative phosphorylation]], [[Phenylalanine]], [[Tyrosine]]

'''Nutrients:''' [[Copper]], [[Deadlock quartet]], [[Folate]], [[L-carnitine]], [[Magnesium]], [[Sam-e]], [[TMG]], [[Vitamin B2]], [[Vitamin B6]], [[Vitamin B12]], [[Vitamin C]], [[Vitamin D]], [[Zinc]]

'''Neurotransmitters and hormones''': [[Acetylcholine]], [[Alpha-Melanocyte-stimulating hormone]], [[Calicitriol]], [[Calcidiol]], [[Cortisol]], [[Dopamine]], [[Estriadol]], [[Epinephrine]], [[Estrogen]], [[Glucocorticoid]], [[Glutamate]], [[Histamine]], [[Hormones]], [[Leptin]], [[Melatonin]], [[Neurotransmitters]], [[Norepinephrine]], [[Oxytocin]], [[Progesterone]], [[Prolactin]], [[Prostaglandins]], [[Serotonin]], [[Testosterone]], [[Vasopressin]], [[Thyroid]], [[MSH]], [[HGH]]

[[Blood donation]]

==Names & Definitions==
'''Names:''' [[Myalgic Encephalomyelitis]], [[Chronic Fatigue Syndrome]], [[ME/CFS]], [[Systemic Exertion Intolerance Disease]], [[Chronic Fatigue Immune Deficiency Syndrome]], [[Chronic epstein barr]], [[Neuro-Inflammatory and Oxidative Fatigue]], [[Yuppie Flu]], [[Neurasthenia]], [[Chronic Fatigue]], [[Infectious Venulitis]]

'''Related conditions:''' [[Chronic lyme disease]], [[Mold illness]], [[Biotoxin illness]], [[Environmental illness]], [[Multiple Chemical Sensitivity]], [[Gulf War Illness]], [[Mast cell activation disorder]], [[Mastocytosis]], [[Ehlers Danlos Syndrome]], [[Fibromyalgia]], [[Small intestine bacterial overgrowth]], [[Lactic acidosis]], [[Autoimmune disease]], [[Cancer]], [[Thyroid disease]], [[Non-Hodgkin's lymphoma]], [[Multiple Sclerosis]], [[Dysautonomia]], [[Mitochondrial disorders]], [[Chronic Epstein Barr]], [[Raynaud's Syndrome]]

'''Definitions:''' [[Definitions of ME and CFS]], [[Canadian Consensus Criteria]], [[International Consensus Criteria]], [[Oxford criteria]], [[Fukuda criteria]], [[Holmes criteria]], [[Empirical definition]], [[Ramsay definition]], [[London criteria]], [[Nightingale definition]], [[Reeves criteria]]

'''Acronyms:''' [[List of acronyms]]

==Potential treatments==

'''Category page''': [[Treatments|Potential treatments]]

'''Supplements:''' [[Probiotics]], [[AHCC]], [[CoQ10]], [[L-carnitine]], [[MitoQ]], [[NADH]], [[PrescriptAssist]], [[Mutaflor]], [[GcMAF]], [[Colostrum]], [[Transfer factors]], [[Fish oil]], [[EPA]], [[DHA]], [[Taurine]], [[L-Glutamine]], [[Glutathione]], [[Niacinamide]], [[B Vitamin Complex]], [[Adaptogens]] ([[Eleuthro]], [[Ginseng]], [[Ashwaganda]], [[Rhodiola]], [[Licorice]]), [[Mangosteen]], [[Vegan/non-whey Protein Powders with Amino Acid Complex]], [[Greens Powders]], [[D-Ribose]], [[Quercetin]], [[Nexavir]], [[5-Hydroxytryptophan]], [[Melatonin]]

'''Supplement Sources:''' [[Pure Formulas]], [[Be Well By Dr Frank Lipman]], [[Seeking Health]], [[MITOQ]], [[Aloha]], [[ProHealth]], [[Thrive Marketplace]], [[HolisticHeal]], [[Vitacost.com]]

'''Foods:''' [[Cocoa|Cocoa (Dark chocolate)]]

'''Herbs:''' [[Medical marijuana]], [[Kampo]], [[Equilibrium]]

'''Diets:''' [[GAPS diet]], [[Ketogenic diet]], [[Low FODMAP diet|Low FODMAP Diet]], [[Low histamine diet|Low Histamine Diet]], [[Paleo diet]], [[RPAH elimination diet|RPAH Elimination Diet]], [[Specific carbohydrate diet]], [[Vegan diet]], [[Vegetarian diet]]

'''Antivirals:''' [[Valgancyclovir]], [[Famciclovir]], [[Valaciclovir]], [[Acyclovir]]

'''Immunomodulators and immunostimulants:''' [[Ampligen]], [[Low dose naltrexone]], [[Equilibrant]], [[Intravenous immunoglobulin]], [[Staphylococcal vaccine]], [[Immunovir]], [[Medicinal mushrooms]], [[Interferon]]

'''Anti-inflammatory drugs:''' [[Sulfasalazine]]

'''Anti-fungal drugs:''' [[fluconazole]], [[itraconazole]]

'''Other drug treatments:''' [[Chelation]], [[Cyclophosphamide]], [[Prednisone]], [[Rituximab]], [[Trazodone]]

'''Toxin avoidance/removal:''' [[Fasting]], [[Mold avoidance]], [[Coffee enema]]

'''Uncategorized interventions:''' [[Traditional Chinese medicine]], [[Cold immersion]], [[Fecal matter transplant]]/[[Faecal bacteriotherapy]], [[Helminthic therapy]], [[Pacing]], [[Energy envelope]], [[Hyperbaric oxygen]], [[Ozone]], [[Altitude]], [[Exercise]], [[Vagus nerve stimulation]], [[Exercise based on 2-day CPET]], [[Lipid replacement therapy]]

'''Management guides:''' [https://www.actionforme.org.uk/uploads/taming-the-gorilla-booklet.pdf Taming the Gorilla] ([[Action for ME]]), [http://stonebird.co.uk/Notes/index.html Notes for Carers] ([[Greg Crowhurst]]), [http://www.meassociation.org.uk/2014/07/our-purple-booklet-clear-clinical-guidance-and-the-latest-research-all-wrapped-up-in-52-pages/ The Purple Booklet] ([[ME Association]])

==Doctors==
'''Clinical Doctors, USA:''' [[Lucinda Bateman]] (UT) [[Derek Enlander]]; [[Susan Levine]] (NY)
[[Nancy Klimas]] (FL) [[Courtney Craig]]; [[Daniel Peterson]] (NV) [[Phillipe Bottello]]; [[John Chia]]; [[OMI Clinic: David Kaufman and Andy Kogelnick]] (CA) [[Jacob Teitelbaum]]; [[Richard Podell]] (NJ) [[Laura Black]] (NC); [[Amy Yasko]]; [[Jose Montoya]] (CA)

'''Clinical Doctors, UK:''' [[Sarah Myhill]], [[William Weir]], [[Nigel Speight]], [[Peter Behan]], [[Charles Shepherd]], [[Gabrielle Murphy]], [[Amolak Bansal]]

'''Clinical Doctors, Germany:''' [[Anna Dorothea Hoeck]], [[Carmen Scheibenbogen]]

'''Clinical Doctors, Belgium:''' [[Kenny de Meirleir]], [[Annemie Uyttersprot (GP)]]

'''Clinical Doctors, South Africa:''' [[Cecile Jadin]]

'''Clinical Doctors, Sweden:''' [[Carl-Gerhard Gottfries]]

'''Clinical Doctors, Italy:''' [[Umberto Tirelli]], [[Lorenzo Lorusso]], [[Eligio Pizzigallo]]

'''Clinical Doctors, Australia:''' [[Donald P Lewis]] (VIC), [[John Whiting]], [[Rashmi Cabena]] (VIC), [[Richard Schloeffel]] (NSW)

==Research==

'''[[Notable studies]]'''

''' Research initiatives USA:''' [[Chronic Fatigue Syndrome Project]], [[Open Medicine Foundation]], [[Chronic Fatigue Initiative]], [[Stanford ME/CFS Initiative]], [[Microbe Discovery Project]], [[Bateman Horne Center]], [[Workwell Foundation]], [[Center for Infection & Immunity]], [[Solve ME/CFS Initiative]], [[Simmaron Research]], [[Treatment Center for CFS]]

''' Researchers USA:''' [[Marcie Zinn]], [Ronald Davis]], [[Jarred Younger]], [[Alan Light]], [[Kathleen Light]], [[Andreas Kogelnik]], [[Leonard Jason]], [[Jose Montoya]], [[David Bell]], [[Mady Hornig]], [[Eric Schadt]], [[Ian Lipkin]], [[John Chia]], [[Rosemary Underhill]], [[Suzanne Vernon]], [[David Berg]], [[Nancy Klimas]], [[Dane Cook]], [[Staci Stevens]], [[Mark VanNess]], [[Christopher Snell]], [[Zaher Nahle]], [[Rich Van Konyenburg]], [[Judy Mikovits]], [[Paul Cheney]], [[Michael Van ElZakker]], [[Zaher Nahle]], [[Michael Zeineh]], [[Anthony Komaroff]], [[A Martin Lerner]]

''' Research initiatives Europe:''' [[ME Research UK]], [[Cure ME]] (UK), [[Invest in ME]] (UK), [[UK CFS/ME Collaborative]], [[Grand Challenge]], [[Invest in ME Conference]] (UK), [[Ramsay Research Fund]] (UK), [[European ME Research Group]], [[Charité Berlin]] (Germany), [[Wake-Up Call]] (Belgium)

'''Research initiatives Australia:''' [[National Centre for Neuroimmunology and Emerging Diseases]], [[Victoria University]]

'''Research initiatives Canada:''' [[Nightingale Research Foundation]]

''' Researchers UK:''' [[Melvin Ramsay]], [[Donald Acheson]], [[Gordon Parish]], [[Jonathan Kerr]], [[Amolak Bansal]], [[Julia Newton]], [[Elizabeth Dowsett]], [[Simon Carding]], [[James Mowbray]], [[John Richardson]], [[Luis Nacul]], [[Derek Pheby]], [[Jonathan Edwards]], [[Geraldine Cambridge]], [[George Davey Smith]], [[Neil Harrison]]

''' Researchers Australia:''' [[Amy Wallis]], [[Donald P Lewis]], [[Donald Staines]], [[Dorothy Bruck]], [[Elaine DeFreitas]], [[Henry Butt]], [[Melinda L Jackson]], [[Michael Maes]], [[Sonya Marshall-Gradisnik]]

''' Researchers Germany:''' [[Carmen Scheibenbogen]]

''' Researchers Norway:''' [[Olav Mella]], [[Øystein Fluge]]

''' Researchers Canada:''' [[Byron Hyde]], [[Patrick O. McGowan]]

'''Researchers Japan:'''

'''Biobanks & patient registries''': [[CURE ME]] (UK), [[OMI OpenMedNet]] (US), [[CFI CFS BioBank]] (US), [[SolveCFS BioBank]] (US), [[Simmaron Research BioBank]] (US)

'''Researcher mailing lists:''' [[CureME mailing list]]

==Psychological Paradigm==
'''Psychological paradigm, mind-body approaches and related interventions:''' [[FINE trial]], [[PACE trial]], [[Graded exercise therapy|Graded Exercise Therapy]], [[cognitive behavioral therapy|Cognitive Behavioral Therapy]], [[biopsychosocial]], [[Deconditioning]], [[Mickel therapy]], [[Lightning process]], [[Gupta programme]], [[Psychoneuroimmunology]], [[Meditation]], [[Bodily distress syndrome]], [[Functional somatic syndrome]], [[Psychosomatic illness]], [[Neurasthenia]], [[Medically unexplained symptoms]]

'''Psychological paradigm proponents:''' [[Simon Wessely]], [[Michael Sharpe]], [[Peter White]], [[Trudie Chalder]], [[Rona Moss-Morris]], [[Jessica Bavinton]], [[Esther Crawley]], [[Anthony Cleare]], [[Ben Goldacre]], [[Peter Manu]], [[Brian Walitt]]

'''Psychological paradigm critics:''' [[James Coyne]], [[Keith Laws]], [[David Tuller]], [[Ronald Davis]], [[Bruce Levin]], [[Arthur Reingold]], [[Jonathan Edwards]], [[Leonard Jason]], [[Ellen Goudsmit]], [[Angela Kennedy]]

[[Patient mental health]]

==Around the world==
*'''Asia:''' [[China]], [[India]], [[Indonesia]], [[Israel]], [[Japan]], [[Russia]]
*'''Africa:''' [[Kenya]], [[Nigeria]]
*'''Europe:''' [[Austria]], [[Belgium]], [[Bulgaria]], [[Czech Republic]], [[Denmark]], [[Finland]], [[France]] [[Germany]], [[Greece]], [[Hungary]], [[Ireland]], [[Italy]], [[Netherlands]], [[Norway]], [[Poland]], [[Romania]], [[Slovakia]], [[Slovenia]], [[Spain]], [[Sweden]], [[Ukraine]], [[United Kingdom]]
*'''North America:''' [[Canada]], [[Mexico]], [[United States]]
*'''South America:''' [[Argentina]], [[Brazil]]
*'''Australia & New Zealand:''' [[Australia]], [[New Zealand]]

==History==

[[Important events timeline]]

'''Historical records''': [[Osler's Web]], [[Thirty Years of Disdain]]

'''Outbreaks:''' [[List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks|Outbreaks]]: [[Incline village|Incline village 1984]], [[1985 Lyndonville outbreak|Lyndonville 1985]], [[Akureyri]], [[1934 Los Angeles outbreak|Los Angeles 1934]], [[Royal Free Hospital outbreak|Royal Free Hospital 1955]], [[1955 Dalston outbreak|Dalston 1955]], [[1949 Adelaide outbreak|Adelaide 1949]], [[1980-81 Ayrshire outbreak|Ayrshire 1980]], [[1975 Sacramento outbreak|Sacramento 1975]]

'''Deceased patients:''' [[Sophia Mirza]], [[Thomas Hennessy, Jr.]], [[Vanessa Li]], [[Lynn Gilderdale]], [[Emily Collingridge]], [[Chardale Dotson Irvine]], [[Oliver Coles]], [[Brynmor John]], [[Victoria Elsbury-Legg]], [[Roger Cicero]], [[Memorial Lists]]

'''Major developments/controversies:''' [[PACE trial]], [[XMRV]]

[[ME and CFS in popular culture]]

==Patient Advocacy==

'''Patient Groups Australia:''' [[Emerge Australia]], [[ME/CFS Australia (SA) Inc]], [[ME/CFS Society of Western Australia]], [[ME/CFS Society of NSW]], [[ME/CFS Society of ACT]]

'''Patient Groups Belgium:''' [[Wake Up Call Beweging]]

'''Patient Groups Canada:''' [[National ME/FM Action Network]], [[May12th.org]], [[Action CIND]]

'''Patient Groups Ireland:''' [[Irish ME/CFS Association]], [[Irish ME Trust]]

'''Patient Groups Italy:''' [[Associazione Malati CFS onlus]], [[CFS Associazione Italiana onlus]], [[CFS Italia]]

'''Patient Groups Netherlands:''' [[ME Vereniging Nederland]]

'''Patient Groups New Zealand:''' [[Associated New Zealand ME Society]] (ANZMES)

'''Patient Groups Norway:''' [[ME-Forskning]]

'''Patient Groups Sweden:''' [[Riksföreningen för ME-patienter]]

'''Patient Groups UK:''' [[Action for ME]], [[Invest in ME]], [[Change For M.E. Change For Us]], [[Norfolk & Suffolk ME]], [[ME Association]], [[Tymes Trust]], [[MEActionUK]], [[Forward-ME]], [[Hope 4 ME & Fibro NI]], [[Welsh Association of ME & CFS Support]], [[Sussex & Kent ME/CFS Society]], [[Association of Young People with ME]], [[Tyne & Wear ME/CFS Support Group]], [[Edinburgh MESH]], [[Leeds ME Network]], [[The York ME Community]], [[25 Percent ME Group]]

'''Patient Groups USA:''' #[[MEAction]], [[MEadvocacy]], [[National Alliance for Myalgic Encephalomyelitis]], [[Massachusetts CFIDS/ME & FM Association]], [[May12.org]]

'''Advocacy/Fundraising Initiatives:''' [[Chilli ME Challenge]], [[ME Foggy Dog]]

'''Famous patients''': [[Laura Hillenbrand]], [[Martine McCutcheon]], [[Stuart Murdoch]], [[Charles Darwin]], [[Florence Nightingale]], [[Roger Cicero]], [[Shirley Conran]], [[Michael Crawford]]

'''Notable patients:''' [[Karina Hansen]], [[Joanne]], [[Sophia Mirza]], [[Thomas Hennessy, JR.]], [[Vanessa Li]], [[Lynn Gilderdale]], [[Emily Collingridge]], [[Whitney Dafoe]], [[Tom Kindlon]], [[Graham McPhee]], [[Jennie Spotila]], [[Naomi Whittingham]], [[Jane Colby]], [[Countess of Mar]], [[Brian Vastag]], [[Jennifer Brea]], [[Ryan Prior]], [[Hillary Johnson]], [[Julie Rehmeyer]], [[Leonard Jason]], [[Charles Shepherd]], [[Nasim Marie Jafry]], [[Ken Lassesen]], [[Cort Johnson]], [[Valerie Eliot Smith]], [[Doctor Speedy]], [[Tanya Marlow]], [[Deborah Waroff]], [[Beth Mazur]], [[Catherine Hale]], [[Mary Schweitzer]], [[Toni Bernhard]], [[Guido den Broeder]], [[Frank Twisk]], [[Steven Lubet]], [[Giada Da Ros]], [[Roberta Pelletta]], [[Carol Head]], [[Ean Proctor]], [[Jessica Taylor]], [[Clark Ellis]], [[Alem Matthews]], [[Peter Kemp]], [[Mindy Kitei]] [[Jeanette Burmeister]], [[Giles Meehan]], [[Erik Johnson]], [[Lisa Petrison]], [[Mary Ann Kindel]], [[Gabby Klein]], [[Eileen Holderman]], [[Susan Kreutzer]], [[Maryann Spurgin]], [[Wendy Boutiler]], [[L.A. Cooper]]

'''Notable healthy advocates:''' [[Angela Kennedy]], [[Mary Dimmock]], [[Greg Crowhurst]], [[Malcolm Hooper]], [[Nicole Castillo]], [[Llewellyn King]], [[Erica Verrillo]], [[Tom Whittingham]], [[Mike Harley]], [[Ian Gibson]], [[Scott Ludlam]], [[Linda and Don Tannenbaum]], [[Jon Campling]]

'''Notable Quotes:''' [[List of Quotes]], [[Individual Quotes]]

==Journals, TV, Articles, Books, Film, Interviews, Blogs, Discussion Forums==

'''Journals:'''
[[The Lancet]]
[[Lancet Psychiatry]] [[The BMJ]] [[Journal of Chronic Fatigue Syndrome]]

'''TV:''' [[Sick and Tired]] (US), [[Sick and Tired - BBC]] (UK), [[Toxic Tiredness]], [[I Remember Me]], [[BBC Documentary on life with severe ME/Chronic Fatigue Syndrome]] (UK)

'''Articles:''' [[List of news articles on ME and CFS]]

'''Books:''' [[Plague]], [[The State of Me]], [[Love and Fatigue in America]], [[Osler's Web]], [[America's Biggest Cover-Up]], [[Reviving the Broken Marionette]], [[Why ME?]], [[Stanchi: Vivere con la Sindrome da Fatica Cronica]], [[Stanchi si diventa]], [[Frammenti di ME]], [[Encounters with the Invisible]], [[Chronic Fatigue Syndrome: A Treatment Guide]], [[Chronic Fatigue Syndrome: A Treatment Guide - 2nd Edition]], [[Severe ME/CFS: A Guide to Living]], [[Severe ME - Featuring: "Justice for Karina Hansen"]], [[Severe ME: Notes for Carers]], [[One Last Goodbye]], [[Authors of our Own Misfortune? The Problems with Psychogenic Explanations for Physical Illnesses]].

'''Film:''' [[What About ME]], [[I Remember Me]], [[Forgotten Plague]], [[Canary in a Coal Mine]], [[The Last Great Medical Cover Up]], [[Invisible Illness - Stories of Chronic Fatigue Syndrome]], [[Voices from the Shadows]]

'''Interviews:'''
[[ME/CFS Alert]], [[Science for Patients]]

'''Blogs:''' [[Health Rising]], [[Occupy CFS]], [[MEAction]], [[ME Advocacy]], [[Courtney Craig]], [[Cell Fatigue]], [[CFS Patient Advocate]], [[Constant F****** S***]], [[ME Association]], [[Onward Through the Fog]], [[Nice Guidelines]], [[Valerie Eliot Smith Blog]], [[CFS Remission]], [[About.com Health FMS/ME/CFS]], [[Just ME]], [[ME/CFS Ghost]]

'''Discussion Forums:''' [[Phoenix Rising]], [[CFSItalia]], [[MDJunction]]

== [[Open Letters]] ==

MEpedia:Contents

2016-04-05T03:00:26Z

Beth:/* Research */ added Leonard Jason

We are crowd-sourcing a knowledge base on the history, science and medicine of ME and CFS around the world. MEpedia is a patient community project being built by patients, founded by #[[MEAction]]. Read more [[MEpedia:About|about MEpedia and its principles]].

Want to take a look around? See our most [[Special:PopularPages|popular pages]], check our [[Special:NewPages|newest pages]], or visit a [[Special:random|random page]]. You can also browse a [[Special:AllPages|list of all pages]].

==Please contribute==
Anyone can create pages, write content, add links/citations, fact-check, or even just fix typos. Get involved and help the patient community identify all of the best and most important resources for our disease and its research, treatment and history. Start now, read [[How to contribute]]. Please join the MEpedia [http://my.meaction.net/local_chapters/mepedia online forum], [https://www.facebook.com/mepedia/ Facebook group], and follow us on [https://twitter.com/MEencyclopedia Twitter].

==Five minute tasks==

Only have a five minute spoon to give? Here is a [[List of small tasks|list of small tasks]] you can help us with in roughly one to ten minutes of time.

==Priority pages for expansion==

'''Science:''' [[Citric acid cycle]], [[Mitochondria]], [[Exercise]], [[Ampligen]], [[Natural killer cell]], [[Central nervous system]], [[Nitric oxide hypothesis]], [[Brain]], [[Brain imaging]]

'''History and politics:'''

==A note on ME v. CFS==

We have separate pages for [[Myalgic Encephalomyelitis]], [[ME/CFS]] and [[Chronic Fatigue Syndrome]] as well as [[SEID]]. The convention is that the terminology used in an ME-pedia article should match the terminology used in the underlying source. Where there is a tension between the term used in the source and the definition (e.g., [[ME]] defined by the [[Oxford criteria]] or [[CFS]] defined by the [[Canadian Consensus Criteria]]), it may be useful for clarity to mention the definition used.

==Primers==
*[[Primer for doctors and researchers]]
*[[Primer for patients]]
*[[Primer for science journalists]]
*[[Primer for the public]]
*[[Primer for family, friends and care providers]]

==The Disease==

'''Infectious agents:''' [[Borrelia]], [[Babesia]], [[Bartonella]], [[Borna Disease Virus]], [[Chlamydia pneumoniae]], [[Coxsackie A]], [[Coxsackie B]], [[cytomegalovirus]], [[Ebola virus]], [[echovirus]], [[enterovirus]], [[Epstein-Barr virus]], [[H1N1]], [[Herpesvirus]], [[HHV-6]], [[HHV-7]], [[HSV-1]], [[HSV-2]], [[influenza]], [[parvovirus B19]], [[Q Fever]], [[Ross River Virus]], [[Chlamydia Pneumonia]], [[Mycoplasma Pneumonia]], [[streptococcus]], [[fungal infection]]

'''Triggers and risk factors:''' [[Blood donation]], [[Candidiasis]], [[Causes of death]], [[Epidemiology]], [[Genetics]], [[Menstrual cycle]], [[Mold]], [[Pediatric]], [[Pregnancy]], [[Stress]], [[Toxic exposure]], [[Trauma]], [[Vaccine]], [[Viral onset]], [[bacterial disease onset]], [[fungal disease onset]]

'''Signs and symptoms:''' [[Ataxia]], [[attention deficits]], [[auditory sequencing problems]], [[balance problems]], [[Cognitive dysfunction]], [[Chronic pain]], [[Chronic fatigue]], [[concentration problems]], [[difficulty comprehending social cues]], [[dyslexia]], [[executive function problems]], [[Fatigue]], [[Food intolerance]], [[Irritable bowel syndrome]], [[low motivation]], [[Migraine Syndrome]], [[multi-tasking problems]], [[Muscle fatigability]], [[Neurally mediated hypotension]], [[Nonepileptic seizure]], [[Optical dysfunction]], [[Orientation in Space problems]], [[Orthostatic intolerance]], [[Planning problems]], [[Post-exertional malaise]], [[Postural orthostatic tachycardia]], [[Receptive language problems]], [[Seizure]], [[Sleep disturbance]], [[Slowed thought]], [[Unrefreshing sleep]], [[Word-finding problems]]

'''Medical hypotheses:''' [[Amygdala hypothesis]], [[Autoimmune hypothesis]], [[encephalitis]], [[autoimmune encephalitis]], [[Fatty acid hypothesis]], [[Hygiene hypothesis]], [[Immune exhaustion hypothesis]], [[Infectious disease hypothesis]], [[Ken Lassesen's model]], [[Methylation cycle hypothesis]], [[Microbiome hypothesis]], [[Mold hypothesis]], [[Patricia Kane protocol]], [[Vagus nerve hypothesis]], [[Viral onset hypothesis]] [[Hypercoagulation hypothesis]] [[Acquired immune and mitochondrial dysfunction hypothesis]]

'''Body systems:''' [[Antibody]], [[Autoantibody]], [[Blood]], [[Brain]], [[B cell]], [[Central sensitization]], [[Cytokine]], [[Chemokine]], [[Cardiovascular system]], [[Gastrointestinal system]], [[Glutamate excitotoxicity]], [[HPA axis]], [[Immune system]], [[IL-1]], [[IL-2]], [[IL-6]], [[IL-8]], [[IL-10]], [[IL-16]], [[IL-17]], [[IL-18]], [[interferon]], [[Leaky brain]], [[Leaky gut]], [[Macrophage]], [[Microglia]], [[Microbiome]], [[Mucosal immune system]], [[Nervous system]], [[Natural killer cell]], [[Neuroinflammation]], [[Ribonuclease L]], [[Spinal cord]], [[Tumor necrosis factors]], [[VEGF]], [[T cell]]

'''Tests:''' [[Brain imaging]], [[Cardiopulmonary exercise test]], [[CellTrend diagnostic test]], [[C reactive protein]], [[qEEG/LORETA]], [[Erythrocyte sedimentation rate]], [[Exercise]], [[National Centre for Neuroimmunology and Emerging Diseases#Potential biomarker|NCNED Griffith University diagnostic test]], [[MRI]], [[Orosomucoid]], [[qEEG]], [[SF-36]], [[SPECT]], [[Tilt Table]], [[Two day exercise test]], [[Natural Killer Cell (NKC) Function]], [[arginine vasopressin]], [[MTHFR and other methylation mutations]], [[infectious disesases]]

'''Citizen science:''' [[23andMe]], [[American Gut]], [[Any Treatment]], [[Mendus]], [[Phoenix Rising]], [[UBiome]], [[Know Your Genetics: Dr. Amy Yasko]], [[WellnessFX]], [[CH3Nutrigenomics; Dr. Amy Yasko]], [[MTHFR.net]], [[Genetic Genie]], [[LiveWello]]

'''Biochemistry and cell biology:''' [[ATP]], [[Cellular respiration]], [[Citric acid cycle]], [[D lactate]], [[Endocannabinoid]], [[Glucocorticoid]], [[Glutathione]], [[Histamine]], [[Methylation cycle]], [[Mitochondria]], [[Nitric oxide]], [[Oxidative phosphorylation]], [[Phenylalanine]], [[Tyrosine]]

'''Nutrients:''' [[Copper]], [[Deadlock quartet]], [[Folate]], [[L-carnitine]], [[Magnesium]], [[Sam-e]], [[TMG]], [[Vitamin B2]], [[Vitamin B6]], [[Vitamin B12]], [[Vitamin C]], [[Vitamin D]], [[Zinc]]

'''Neurotransmitters and hormones''': [[Acetylcholine]], [[Alpha-Melanocyte-stimulating hormone]], [[Calicitriol]], [[Calcidiol]], [[Cortisol]], [[Dopamine]], [[Estriadol]], [[Epinephrine]], [[Estrogen]], [[Glucocorticoid]], [[Glutamate]], [[Histamine]], [[Hormones]], [[Leptin]], [[Melatonin]], [[Neurotransmitters]], [[Norepinephrine]], [[Oxytocin]], [[Progesterone]], [[Prolactin]], [[Prostaglandins]], [[Serotonin]], [[Testosterone]], [[Vasopressin]], [[Thyroid]], [[MSH]], [[HGH]]

[[Blood donation]]

==Names & Definitions==
'''Names:''' [[Myalgic Encephalomyelitis]], [[Chronic Fatigue Syndrome]], [[ME/CFS]], [[Systemic Exertion Intolerance Disease]], [[Chronic Fatigue Immune Deficiency Syndrome]], [[Chronic epstein barr]], [[Neuro-Inflammatory and Oxidative Fatigue]], [[Yuppie Flu]], [[Neurasthenia]], [[Chronic Fatigue]], [[Infectious Venulitis]]

'''Related conditions:''' [[Chronic lyme disease]], [[Mold illness]], [[Biotoxin illness]], [[Environmental illness]], [[Multiple Chemical Sensitivity]], [[Gulf War Illness]], [[Mast cell activation disorder]], [[Mastocytosis]], [[Ehlers Danlos Syndrome]], [[Fibromyalgia]], [[Small intestine bacterial overgrowth]], [[Lactic acidosis]], [[Autoimmune disease]], [[Cancer]], [[Thyroid disease]], [[Non-Hodgkin's lymphoma]], [[Multiple Sclerosis]], [[Dysautonomia]], [[Mitochondrial disorders]], [[Chronic Epstein Barr]], [[Raynaud's Syndrome]]

'''Definitions:''' [[Definitions of ME and CFS]], [[Canadian Consensus Criteria]], [[International Consensus Criteria]], [[Oxford criteria]], [[Fukuda criteria]], [[Holmes criteria]], [[Empirical definition]], [[Ramsay definition]], [[London criteria]], [[Nightingale definition]], [[Reeves criteria]]

'''Acronyms:''' [[List of acronyms]]

==Potential treatments==

'''Category page''': [[Treatments|Potential treatments]]

'''Supplements:''' [[Probiotics]], [[AHCC]], [[CoQ10]], [[L-carnitine]], [[MitoQ]], [[NADH]], [[PrescriptAssist]], [[Mutaflor]], [[GcMAF]], [[Colostrum]], [[Transfer factors]], [[Fish oil]], [[EPA]], [[DHA]], [[Taurine]], [[L-Glutamine]], [[Glutathione]], [[Niacinamide]], [[B Vitamin Complex]], [[Adaptogens]] ([[Eleuthro]], [[Ginseng]], [[Ashwaganda]], [[Rhodiola]], [[Licorice]]), [[Mangosteen]], [[Vegan/non-whey Protein Powders with Amino Acid Complex]], [[Greens Powders]], [[D-Ribose]], [[Quercetin]], [[Nexavir]], [[5-Hydroxytryptophan]], [[Melatonin]]

'''Supplement Sources:''' [[Pure Formulas]], [[Be Well By Dr Frank Lipman]], [[Seeking Health]], [[MITOQ]], [[Aloha]], [[ProHealth]], [[Thrive Marketplace]], [[HolisticHeal]], [[Vitacost.com]]

'''Foods:''' [[Cocoa|Cocoa (Dark chocolate)]]

'''Herbs:''' [[Medical marijuana]], [[Kampo]], [[Equilibrium]]

'''Diets:''' [[GAPS diet]], [[Ketogenic diet]], [[Low FODMAP diet|Low FODMAP Diet]], [[Low histamine diet|Low Histamine Diet]], [[Paleo diet]], [[RPAH elimination diet|RPAH Elimination Diet]], [[Specific carbohydrate diet]], [[Vegan diet]], [[Vegetarian diet]]

'''Antivirals:''' [[Valgancyclovir]], [[Famciclovir]], [[Valaciclovir]], [[Acyclovir]]

'''Immunomodulators and immunostimulants:''' [[Ampligen]], [[Low dose naltrexone]], [[Equilibrant]], [[Intravenous immunoglobulin]], [[Staphylococcal vaccine]], [[Immunovir]], [[Medicinal mushrooms]], [[Interferon]]

'''Anti-inflammatory drugs:''' [[Sulfasalazine]]

'''Anti-fungal drugs:''' [[fluconazole]], [[itraconazole]]

'''Other drug treatments:''' [[Chelation]], [[Cyclophosphamide]], [[Prednisone]], [[Rituximab]], [[Trazodone]]

'''Toxin avoidance/removal:''' [[Fasting]], [[Mold avoidance]], [[Coffee enema]]

'''Uncategorized interventions:''' [[Traditional Chinese medicine]], [[Cold immersion]], [[Fecal matter transplant]]/[[Faecal bacteriotherapy]], [[Helminthic therapy]], [[Pacing]], [[Energy envelope]], [[Hyperbaric oxygen]], [[Ozone]], [[Altitude]], [[Exercise]], [[Vagus nerve stimulation]], [[Exercise based on 2-day CPET]], [[Lipid replacement therapy]]

'''Management guides:''' [https://www.actionforme.org.uk/uploads/taming-the-gorilla-booklet.pdf Taming the Gorilla] ([[Action for ME]]), [http://stonebird.co.uk/Notes/index.html Notes for Carers] ([[Greg Crowhurst]]), [http://www.meassociation.org.uk/2014/07/our-purple-booklet-clear-clinical-guidance-and-the-latest-research-all-wrapped-up-in-52-pages/ The Purple Booklet] ([[ME Association]])

==Doctors==
'''Clinical Doctors, USA:''' [[Lucinda Bateman]] (UT) [[Derek Enlander]]; [[Susan Levine]] (NY)
[[Nancy Klimas]] (FL) [[Courtney Craig]]; [[Daniel Peterson]] (NV) [[Phillipe Bottello]]; [[John Chia]]; [[OMI Clinic: David Kaufman and Andy Kogelnick]] (CA) [[Jacob Teitelbaum]]; [[Richard Podell]] (NJ) [[Laura Black]] (NC); [[Amy Yasko]]; [[Jose Montoya]] (CA)

'''Clinical Doctors, UK:''' [[Sarah Myhill]], [[William Weir]], [[Nigel Speight]], [[Peter Behan]], [[Charles Shepherd]], [[Gabrielle Murphy]], [[Amolak Bansal]]

'''Clinical Doctors, Germany:''' [[Anna Dorothea Hoeck]], [[Carmen Scheibenbogen]]

'''Clinical Doctors, Belgium:''' [[Kenny de Meirleir]], [[Annemie Uyttersprot (GP)]]

'''Clinical Doctors, South Africa:''' [[Cecile Jadin]]

'''Clinical Doctors, Sweden:''' [[Carl-Gerhard Gottfries]]

'''Clinical Doctors, Italy:''' [[Umberto Tirelli]], [[Lorenzo Lorusso]], [[Eligio Pizzigallo]]

'''Clinical Doctors, Australia:''' [[Donald P Lewis]] (VIC), [[John Whiting]], [[Rashmi Cabena]] (VIC), [[Richard Schloeffel]] (NSW)

==Research==

'''[[Notable studies]]'''

''' Research initiatives USA:''' [[Chronic Fatigue Syndrome Project]], [[Open Medicine Foundation]], [[Chronic Fatigue Initiative]], [[Stanford ME/CFS Initiative]], [[Microbe Discovery Project]], [[Bateman Horne Center]], [[Workwell Foundation]], [[Center for Infection & Immunity]], [[Solve ME/CFS Initiative]], [[Simmaron Research]], [[Treatment Center for CFS]]

''' Researchers USA:''' }[Marcie Zinn]][Ronald Davis]], [[Jarred Younger]], [[Alan Light]], [[Kathleen Light]], [[Andreas Kogelnik]], [[Leonard Jason]], [[Jose Montoya]], [[David Bell]], [[Mady Hornig]], [[Eric Schadt]], [[Ian Lipkin]], [[John Chia]], [[Rosemary Underhill]], [[Suzanne Vernon]], [[David Berg]], [[Nancy Klimas]], [[Dane Cook]], [[Staci Stevens]], [[Mark VanNess]], [[Christopher Snell]], [[Zaher Nahle]], [[Rich Van Konyenburg]], [[Judy Mikovits]], [[Paul Cheney]], [[Michael Van ElZakker]], [[Zaher Nahle]], [[Michael Zeineh]], [[Anthony Komaroff]], [[A Martin Lerner]]

''' Research initiatives Europe:''' [[ME Research UK]], [[Cure ME]] (UK), [[Invest in ME]] (UK), [[UK CFS/ME Collaborative]], [[Grand Challenge]], [[Invest in ME Conference]] (UK), [[Ramsay Research Fund]] (UK), [[European ME Research Group]], [[Charité Berlin]] (Germany), [[Wake-Up Call]] (Belgium)

'''Research initiatives Australia:''' [[National Centre for Neuroimmunology and Emerging Diseases]], [[Victoria University]]

'''Research initiatives Canada:''' [[Nightingale Research Foundation]]

''' Researchers UK:''' [[Melvin Ramsay]], [[Donald Acheson]], [[Gordon Parish]], [[Jonathan Kerr]], [[Amolak Bansal]], [[Julia Newton]], [[Elizabeth Dowsett]], [[Simon Carding]], [[James Mowbray]], [[John Richardson]], [[Luis Nacul]], [[Derek Pheby]], [[Jonathan Edwards]], [[Geraldine Cambridge]], [[George Davey Smith]], [[Neil Harrison]]

''' Researchers Australia:''' [[Amy Wallis]], [[Donald P Lewis]], [[Donald Staines]], [[Dorothy Bruck]], [[Elaine DeFreitas]], [[Henry Butt]], [[Melinda L Jackson]], [[Michael Maes]], [[Sonya Marshall-Gradisnik]]

''' Researchers Germany:''' [[Carmen Scheibenbogen]]

''' Researchers Norway:''' [[Olav Mella]], [[Øystein Fluge]]

''' Researchers Canada:''' [[Byron Hyde]], [[Patrick O. McGowan]]

'''Researchers Japan:'''

'''Biobanks & patient registries''': [[CURE ME]] (UK), [[OMI OpenMedNet]] (US), [[CFI CFS BioBank]] (US), [[SolveCFS BioBank]] (US), [[Simmaron Research BioBank]] (US)

'''Researcher mailing lists:''' [[CureME mailing list]]

==Psychological Paradigm==
'''Psychological paradigm, mind-body approaches and related interventions:''' [[FINE trial]], [[PACE trial]], [[Graded exercise therapy|Graded Exercise Therapy]], [[cognitive behavioral therapy|Cognitive Behavioral Therapy]], [[biopsychosocial]], [[Deconditioning]], [[Mickel therapy]], [[Lightning process]], [[Gupta programme]], [[Psychoneuroimmunology]], [[Meditation]], [[Bodily distress syndrome]], [[Functional somatic syndrome]], [[Psychosomatic illness]], [[Neurasthenia]], [[Medically unexplained symptoms]]

'''Psychological paradigm proponents:''' [[Simon Wessely]], [[Michael Sharpe]], [[Peter White]], [[Trudie Chalder]], [[Rona Moss-Morris]], [[Jessica Bavinton]], [[Esther Crawley]], [[Anthony Cleare]], [[Ben Goldacre]], [[Peter Manu]], [[Brian Walitt]]

'''Psychological paradigm critics:''' [[James Coyne]], [[Keith Laws]], [[David Tuller]], [[Ronald Davis]], [[Bruce Levin]], [[Arthur Reingold]], [[Jonathan Edwards]], [[Leonard Jason]], [[Ellen Goudsmit]], [[Angela Kennedy]]

[[Patient mental health]]

==Around the world==
*'''Asia:''' [[China]], [[India]], [[Indonesia]], [[Israel]], [[Japan]], [[Russia]]
*'''Africa:''' [[Kenya]], [[Nigeria]]
*'''Europe:''' [[Austria]], [[Belgium]], [[Bulgaria]], [[Czech Republic]], [[Denmark]], [[Finland]], [[France]] [[Germany]], [[Greece]], [[Hungary]], [[Ireland]], [[Italy]], [[Netherlands]], [[Norway]], [[Poland]], [[Romania]], [[Slovakia]], [[Slovenia]], [[Spain]], [[Sweden]], [[Ukraine]], [[United Kingdom]]
*'''North America:''' [[Canada]], [[Mexico]], [[United States]]
*'''South America:''' [[Argentina]], [[Brazil]]
*'''Australia & New Zealand:''' [[Australia]], [[New Zealand]]

==History==

[[Important events timeline]]

'''Historical records''': [[Osler's Web]], [[Thirty Years of Disdain]]

'''Outbreaks:''' [[List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks|Outbreaks]]: [[Incline village|Incline village 1984]], [[1985 Lyndonville outbreak|Lyndonville 1985]], [[Akureyri]], [[1934 Los Angeles outbreak|Los Angeles 1934]], [[Royal Free Hospital outbreak|Royal Free Hospital 1955]], [[1955 Dalston outbreak|Dalston 1955]], [[1949 Adelaide outbreak|Adelaide 1949]], [[1980-81 Ayrshire outbreak|Ayrshire 1980]], [[1975 Sacramento outbreak|Sacramento 1975]]

'''Deceased patients:''' [[Sophia Mirza]], [[Thomas Hennessy, Jr.]], [[Vanessa Li]], [[Lynn Gilderdale]], [[Emily Collingridge]], [[Chardale Dotson Irvine]], [[Oliver Coles]], [[Brynmor John]], [[Victoria Elsbury-Legg]], [[Roger Cicero]], [[Memorial Lists]]

'''Major developments/controversies:''' [[PACE trial]], [[XMRV]]

[[ME and CFS in popular culture]]

==Patient Advocacy==

'''Patient Groups Australia:''' [[Emerge Australia]], [[ME/CFS Australia (SA) Inc]], [[ME/CFS Society of Western Australia]], [[ME/CFS Society of NSW]], [[ME/CFS Society of ACT]]

'''Patient Groups Belgium:''' [[Wake Up Call Beweging]]

'''Patient Groups Canada:''' [[National ME/FM Action Network]], [[May12th.org]], [[Action CIND]]

'''Patient Groups Ireland:''' [[Irish ME/CFS Association]], [[Irish ME Trust]]

'''Patient Groups Italy:''' [[Associazione Malati CFS onlus]], [[CFS Associazione Italiana onlus]], [[CFS Italia]]

'''Patient Groups Netherlands:''' [[ME Vereniging Nederland]]

'''Patient Groups New Zealand:''' [[Associated New Zealand ME Society]] (ANZMES)

'''Patient Groups Norway:''' [[ME-Forskning]]

'''Patient Groups Sweden:''' [[Riksföreningen för ME-patienter]]

'''Patient Groups UK:''' [[Action for ME]], [[Invest in ME]], [[Change For M.E. Change For Us]], [[Norfolk & Suffolk ME]], [[ME Association]], [[Tymes Trust]], [[MEActionUK]], [[Forward-ME]], [[Hope 4 ME & Fibro NI]], [[Welsh Association of ME & CFS Support]], [[Sussex & Kent ME/CFS Society]], [[Association of Young People with ME]], [[Tyne & Wear ME/CFS Support Group]], [[Edinburgh MESH]], [[Leeds ME Network]], [[The York ME Community]], [[25 Percent ME Group]]

'''Patient Groups USA:''' #[[MEAction]], [[MEadvocacy]], [[National Alliance for Myalgic Encephalomyelitis]], [[Massachusetts CFIDS/ME & FM Association]], [[May12.org]]

'''Advocacy/Fundraising Initiatives:''' [[Chilli ME Challenge]], [[ME Foggy Dog]]

'''Famous patients''': [[Laura Hillenbrand]], [[Martine McCutcheon]], [[Stuart Murdoch]], [[Charles Darwin]], [[Florence Nightingale]], [[Roger Cicero]], [[Shirley Conran]], [[Michael Crawford]]

'''Notable patients:''' [[Karina Hansen]], [[Joanne]], [[Sophia Mirza]], [[Thomas Hennessy, JR.]], [[Vanessa Li]], [[Lynn Gilderdale]], [[Emily Collingridge]], [[Whitney Dafoe]], [[Tom Kindlon]], [[Graham McPhee]], [[Jennie Spotila]], [[Naomi Whittingham]], [[Jane Colby]], [[Countess of Mar]], [[Brian Vastag]], [[Jennifer Brea]], [[Ryan Prior]], [[Hillary Johnson]], [[Julie Rehmeyer]], [[Leonard Jason]], [[Charles Shepherd]], [[Nasim Marie Jafry]], [[Ken Lassesen]], [[Cort Johnson]], [[Valerie Eliot Smith]], [[Doctor Speedy]], [[Tanya Marlow]], [[Deborah Waroff]], [[Beth Mazur]], [[Catherine Hale]], [[Mary Schweitzer]], [[Toni Bernhard]], [[Guido den Broeder]], [[Frank Twisk]], [[Steven Lubet]], [[Giada Da Ros]], [[Roberta Pelletta]], [[Carol Head]], [[Ean Proctor]], [[Jessica Taylor]], [[Clark Ellis]], [[Alem Matthews]], [[Peter Kemp]], [[Mindy Kitei]] [[Jeanette Burmeister]], [[Giles Meehan]], [[Erik Johnson]], [[Lisa Petrison]], [[Mary Ann Kindel]], [[Gabby Klein]], [[Eileen Holderman]], [[Susan Kreutzer]], [[Maryann Spurgin]], [[Wendy Boutiler]], [[L.A. Cooper]]

'''Notable healthy advocates:''' [[Angela Kennedy]], [[Mary Dimmock]], [[Greg Crowhurst]], [[Malcolm Hooper]], [[Nicole Castillo]], [[Llewellyn King]], [[Erica Verrillo]], [[Tom Whittingham]], [[Mike Harley]], [[Ian Gibson]], [[Scott Ludlam]], [[Linda and Don Tannenbaum]], [[Jon Campling]]

'''Notable Quotes:''' [[List of Quotes]], [[Individual Quotes]]

==Journals, TV, Articles, Books, Film, Interviews, Blogs, Discussion Forums==

'''Journals:'''
[[The Lancet]]
[[Lancet Psychiatry]] [[The BMJ]] [[Journal of Chronic Fatigue Syndrome]]

'''TV:''' [[Sick and Tired]] (US), [[Sick and Tired - BBC]] (UK), [[Toxic Tiredness]], [[I Remember Me]], [[BBC Documentary on life with severe ME/Chronic Fatigue Syndrome]] (UK)

'''Articles:''' [[List of news articles on ME and CFS]]

'''Books:''' [[Plague]], [[The State of Me]], [[Love and Fatigue in America]], [[Osler's Web]], [[America's Biggest Cover-Up]], [[Reviving the Broken Marionette]], [[Why ME?]], [[Stanchi: Vivere con la Sindrome da Fatica Cronica]], [[Stanchi si diventa]], [[Frammenti di ME]], [[Encounters with the Invisible]], [[Chronic Fatigue Syndrome: A Treatment Guide]], [[Chronic Fatigue Syndrome: A Treatment Guide - 2nd Edition]], [[Severe ME/CFS: A Guide to Living]], [[Severe ME - Featuring: "Justice for Karina Hansen"]], [[Severe ME: Notes for Carers]], [[One Last Goodbye]], [[Authors of our Own Misfortune? The Problems with Psychogenic Explanations for Physical Illnesses]].

'''Film:''' [[What About ME]], [[I Remember Me]], [[Forgotten Plague]], [[Canary in a Coal Mine]], [[The Last Great Medical Cover Up]], [[Invisible Illness - Stories of Chronic Fatigue Syndrome]], [[Voices from the Shadows]]

'''Interviews:'''
[[ME/CFS Alert]], [[Science for Patients]]

'''Blogs:''' [[Health Rising]], [[Occupy CFS]], [[MEAction]], [[ME Advocacy]], [[Courtney Craig]], [[Cell Fatigue]], [[CFS Patient Advocate]], [[Constant F****** S***]], [[ME Association]], [[Onward Through the Fog]], [[Nice Guidelines]], [[Valerie Eliot Smith Blog]], [[CFS Remission]], [[About.com Health FMS/ME/CFS]], [[Just ME]], [[ME/CFS Ghost]]

'''Discussion Forums:''' [[Phoenix Rising]], [[CFSItalia]], [[MDJunction]]

== [[Open Letters]] ==

Joshua Milner

2016-03-02T02:55:20Z

Beth:

Doctor '''Joshua Milner''' is leads the Genetics and Pathogenesis of Allergy Section in the Laboratory of Allergic Disease in the [[National Institute of Allergy and Infectious Disease]] within the United States [[National Institutes of Health]].

His research interests include T-cell receptor signalling and repertoires, and [[atopy]] (hyperallergy).

==Notable studies==
*[[NIH Post-Infectious ME/CFS Study]]

==Talks & interviews==
*2014, [https://www.youtube.com/watch?v=rwervus7INk JACI Associate Editor Dr. Deborah Meyers talks to Dr. Joshua Milner about his article "Mendelian Inheritance Of Elevated Tryptase Associated With Atopy and Connective Tissue Abnormalities"]
*2014, [https://vimeo.com/142039306 Research update on a gene associated with a POTS/dysautonomia, MCAS, EDS phenotype, presented during Dysautonomia International's 2015 Conference]

==Online presence==
*PubMed
*Twitter
*Facebook
*Website
*YouTube

==Learn more==
*Wikipedia
*[http://www.niaid.nih.gov/labsandresources/labs/aboutlabs/lad/geneticspathogenesisallergy/Pages/milner.aspx NIH - Joshua Milner]

==See also==

==References==
<references/>

[[Category:Researchers]]

David Goldstein

2016-02-27T22:16:01Z

Beth:

Doctor '''David Goldstein''' is a neurocardiologist at the [[Institutes of Health]] in the United States. His research interests are in catecholamine systems, clinical autonomic disorders, and scientific integrative medicine. The Clinical Neurocardiology Section, which he founded and directs, carries out mainly patient-oriented research about disorders of brain regulation of the cardiovascular system.

==Notable studies==
*[[NIH Post-Infectious ME/CFS Study]]

==Talks & interviews==

==Online presence==
*PubMed
*Twitter
*Facebook
*Website
*YouTube

==Learn more==
*[https://irp.nih.gov/pi/david-goldstein NIH - David Goldstein]

==See also==

==References==
<references/>

[[Category:Researchers]]

Brian Walitt

2016-02-20T17:51:37Z

Beth:/* Online presence */

Doctor '''Brian Walitt''' is a pain researcher at the [[National Institutes of Health]] and oversees intramural clinical protocols.

==Research==

==Controversy==

Walitt thinks that [[Fibromyalgia]] is a psychosomatic experience and not an abnormal disease state.<ref>[http://www.familypracticenews.com/specialty-focus/rheumatology/single-article-page/video-fibromyalgia-doesnt-fit-the-disease-model/e913134880916685f3005dac5459ab88.html VIDEO: Fibromyalgia doesn’t fit the disease model]</ref>

==Notable studies==
*[[NIH Post-Infectious ME/CFS Study]]

==Talks & interviews==
*2015, [http://www.familypracticenews.com/specialty-focus/rheumatology/single-article-page/video-fibromyalgia-doesnt-fit-the-disease-model/e913134880916685f3005dac5459ab88.html VIDEO: Fibromyalgia doesn’t fit the disease model]

==Online presence==
*[http://www.ncbi.nlm.nih.gov/pubmed/?term=Walitt%5BAuthor%5D PubMed - Brian Walitt]
*[https://nccih.nih.gov/research/intramural/laboratory-clinical-investigations-branch/staff/walittb NIH - Dr Brian Walitt]

==Learn more==

==See also==
*[[Avindra Nath]]

==References==
<references/>

[[Category:Researchers]]

Brian Walitt

2016-02-20T17:50:43Z

Beth:/* Online presence */

Doctor '''Brian Walitt''' is a pain researcher at the [[National Institutes of Health]] and oversees intramural clinical protocols.

==Research==

==Controversy==

Walitt thinks that [[Fibromyalgia]] is a psychosomatic experience and not an abnormal disease state.<ref>[http://www.familypracticenews.com/specialty-focus/rheumatology/single-article-page/video-fibromyalgia-doesnt-fit-the-disease-model/e913134880916685f3005dac5459ab88.html VIDEO: Fibromyalgia doesn’t fit the disease model]</ref>

==Notable studies==
*[[NIH Post-Infectious ME/CFS Study]]

==Talks & interviews==
*2015, [http://www.familypracticenews.com/specialty-focus/rheumatology/single-article-page/video-fibromyalgia-doesnt-fit-the-disease-model/e913134880916685f3005dac5459ab88.html VIDEO: Fibromyalgia doesn’t fit the disease model]

==Online presence==
*[https://www.ncbi.nlm.nih.gov/pubmed/?term=Walitt[Author]&cauthor=true&cauthor_uid=26834253 PubMed - Brian Walitt]
*[https://nccih.nih.gov/research/intramural/laboratory-clinical-investigations-branch/staff/walittb NIH - Dr Brian Walitt]

==Learn more==

==See also==
*[[Avindra Nath]]

==References==
<references/>

[[Category:Researchers]]

Luigi Ferrucci

2016-02-20T08:07:05Z

Beth:/* Online presence */

Doctor '''Luigi Ferrucci''' is a is a geriatrician and an epidemiologist at the [[National Institutes of Health]] who conducts research on the causal pathways leading to progressive physical and cognitive decline in older persons

==Notable studies==
*[[NIH Post-Infectious ME/CFS Study]]

==Talks & interviews==

==Online presence==
*[https://www.ncbi.nlm.nih.gov/pubmed/?term=Ferrucci%20L%5BAuthor%5D&cauthor=true&cauthor_uid=26873873 PubMed - L Ferrucci]
*[https://www.irp.nia.nih.gov/branches/irp/lferrucci.htm NIH - Luigi Ferrucci]

==Learn more==

==See also==
*[[Avindra Nath]]

==References==
<references/>

[[Category:Researchers]]

Luigi Ferrucci

2016-02-20T08:03:40Z

Beth:/* Online presence */

Doctor '''Luigi Ferrucci''' is a is a geriatrician and an epidemiologist at the [[National Institutes of Health]] who conducts research on the causal pathways leading to progressive physical and cognitive decline in older persons

==Notable studies==
*[[NIH Post-Infectious ME/CFS Study]]

==Talks & interviews==

==Online presence==
*[https://www.irp.nia.nih.gov/branches/irp/lferrucci.htm NIH - Luigi Ferrucci]

==Learn more==

==See also==
*[[Avindra Nath]]

==References==
<references/>

[[Category:Researchers]]

Luigi Ferrucci

2016-02-20T08:01:40Z

Beth:Created page with "Doctor '''Luigi Ferrucci''' is a is a geriatrician and an epidemiologist at the National Institutes of Health who conducts research on the causal pathways leading to prog..."

Doctor '''Luigi Ferrucci''' is a is a geriatrician and an epidemiologist at the [[National Institutes of Health]] who conducts research on the causal pathways leading to progressive physical and cognitive decline in older persons

==Notable studies==
*[[NIH Post-Infectious ME/CFS Study]]

==Talks & interviews==

==Online presence==
*[https://www.irp.nia.nih.gov/branches/irp/lferrucci.htm]

==Learn more==

==See also==
*[[Avindra Nath]]

==References==
<references/>

[[Category:Researchers]]

NIH Post-Infectious ME/CFS Study

2016-02-20T07:59:19Z

Beth:

The [[National Institutes of Health]] (NIH) announced in late 2015 its intention to begin an extensive study of 40 patients with "PI-ME/CFS" ([[Viral onset|Post-Infectious]] ME/CFS) in order to define subgroups, find biomarkers and identify treatments.<ref>[https://www.nih.gov/news-events/news-releases/nih-takes-action-bolster-research-myalgic-encephalomyelitis/chronic-fatigue-syndrome NIH takes action to bolster research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]</ref> The patients will be selected from seven clinical sites around the United States.

==Aims==
Doctor [[Avindra Nath]] stated "The relationship of infections to the onset of ME/CFS and the large body of literature identifying a variety of interesting but inconsistent immune abnormalities in these patients provide a rationale for further studies of immune regulation".<ref name="cdc_grand_rounds_talks">[http://www.meaction.net/2016/02/16/transcripts-and-slides-from-dr-naths-talk-on-nih-study/ Transcripts and slides from Dr Nath's talk on NIH study]
</ref> The study is designed to form three phases:

===Phase 1 - Deep phenotyping===
"To conduct a cross-section study for deep phenotyping of PI-ME/CFS to define its pathophysiology."<ref name="cdc_grand_rounds_talks" />

====Aim 1 - To define the clinical phenotype====
"...the first aim of this study is to define the clinical phenotyping using in-depth assessments of all domains of the illness".<ref name="cdc_grand_rounds_talks" />
*History and physical examination and systemic assessment
*Neurological assessment
*Neurocognitive assessment
*Psychiatric evaluation
*Pain/headache evaluation
*Infectious disease and rheumatologic evaluation by specialists
*Neuro-endocrine evaluation
*Fatigue testing, [[Two day exercise test|exercise capacity]]

====Aim 2 - To understand the underlying physiology of fatigue (pre and post-exercise)====
"Aim two of the study is to define the physiological basis of fatigue using functional MRI scan of the brain to define the brain circuits that are involved. Do detailed metabolic studies in a metabolic chamber and do transcranial magnetic stimulation as well as very detailed autonomic testing. Each of these tests will be performed before and after exercise".<ref name="cdc_grand_rounds_talks" />
*Functional [[MRI]]
*Metabolic studies
*Transcranial magnetic stimulation
*Autonomic function

====Aim 3 - To determine if there are abnormal immune or microbiome profiles====
"The third aim of this study is to conduct a detailed immunological study in blood as well as cerebral spinal fluid including a screen for autoantibodies to neuro antigens. We will also fully explore the gut and oral microbiome and apply proteomics and metabolomics approaches to the cerebral spinal fluid."<ref name="cdc_grand_rounds_talks" />
*[[Cytokine]] & [[chemokine]] profile in cerebrospinal fluid and blood; after [[T cell]] stimulation in culture
*Flow cytometry
*[[B cell]] and [[T cell]] cloning and T cell antigen receptor sequencing
*Immunoglobulin profile
*Autoantibodies directed against brain antigens
*Cerebrospinal fluid proteomics and metabolomics
*Gut and oral [[microbiome]]
*Serum tryptase
*Viral discovery, antibodies to herpes virus

====Aim 4 - To determine if features can be reproduced in ex-vivo studies====
"The fourth aim of this study will utilize a variety of novel approaches to explore whether cells or serum from patients can be used to experimentally reproduce some of the features of the illness. We will determine if there is an inherent metabolic abnormality in neurons derived from stem cells and culture from these patients and if exposure of spinal fluid will induce the functional abnormalities in these cells. We will also generate humanized mice using blood cells from patients and determine if the clinical phenotype can be reproduced in these animals. If these experimental systems are able to reproduce the clinical or biological abnormalities seen in these patients, it would be a major step towards identifying the cause and the pathophysiology of the illness and for developing a variety of treatment approaches to these patients."<ref name="cdc_grand_rounds_talks" />
*To determine if there are functional or mitochondrial abnormalities and electrophysiological properties in induced pluripotent stem cell (iPS) derived neurons from patients with PI-ME/CFS.
*Effect of serum and cerebrospinal fluid on iPS cells and derived neurons.
*To determine if cerebrospinal fluid or antibodies injected in brains of rodents or humanized mice generated with cells from PI-ME/CFS patients can lead to fatigue or behavioral abnormalities.

===Phase 2 - Establish biomarkers===
"To validate select biomarkers from Phase 1 in a longitudinal study and establish objective endpoints for an intervention study."<ref name="cdc_grand_rounds_talks" />

===Phase 3 - Evaluate immunomodulator===
"To conduct an early phase intervention study with an immunomodulatory agent that targets biomarkers found in Phase 2."<ref name="cdc_grand_rounds_talks" />

==Patient recruitment==
"...for the purpose of our phase one study, we plan to recruit patients primarily from well characterized cohorts– particularly the CDC’s M CAM study described earlier by [[Elizabeth Unger|Dr Unger]]. Selection criteria will include documentation of the acute onset and duration of fatiguing illness for more than 6 months but less than five years. All patients will have [[post-exertional malaise]] and full criteria of the [[Fukuda criteria|1994 research case definition]] and the [[Canadian Consensus Criteria]] as mentioned earlier. The study population will include 40 Post infectious ME/CFS patients, 20 healthy controls, 20 Post [[Chronic lyme disease|Lyme Disease]] patients who are asymptomatic – that means they do not have fatigue and 20 patients with [[Functional movement disorder]]s."<ref name="cdc_grand_rounds_talks" />
===Selection criteria===
*Documentation of acute infectious onset process
*Fatigue more than 6 months but less than 5 years
*Meet [[Fukuda criteria | 1994 criteria]] and the [[Canadian Consensus Criteria]]

==Funding==

==Results==
The timing of results publication is unknown.

==Criticism==
Some patients have expressed concern at investigator Doctor [[Brian Walitt]] being a proponent of the [[biopsychosocial]] illness model.<ref>[http://forums.phoenixrising.me/index.php?threads/details-on-nih-study.43076/ Phoenix Rising - Details on NIH study]</ref>

==Investigators==
The principal investigator of the study is Doctor [[Avindra Nath]] and the lead clinical investigator is Doctor [[Brian Walitt]]. Professor [[Ian Lipkin]] (Columbia University) and [[Elizabeth Unger]] ([[Centers for Disease Control]]) are members of the executive committee.

The other investigators are Ana Acevedo, Jeffrey Cohen (infectious disease & virology), Bart Drinkard, [[Luigi Ferrucci]], Penny Friedman, Fred Gill, David Goldstein, Mark Hallett, Wendy Henderson, Silvina Horovitz, Steve Jacobson, Eunhee Kim, Mary Lee, Tanya Lehky, Johnathan Lyons, Eugene Major, Adriana Marques, Carine Maurer (neurologist), Joshua Milner, Leorey Saligan, Stephen Sinclair, Bryan Smith, Joseph Snow, Stacey Solin, Neal Young (immunologist), Jay Chung.

==Patient advisory committee==
There will be a committee of patients, but its members and role are not clear.<ref name="cdc_grand_rounds_talks" />

==Learn more==
*2016, [https://www.youtube.com/watch?v=0SnJy5AOSd8 CDC Grand Rounds - Chronic Fatigue Syndrome: Advancing Research and Clinical Education]
*2016, [http://www.meaction.net/2016/02/17/qa-about-patient-involvement-act-up-and-rfas-with-dr-nath/ Response from Dr Nath about ACT-UP and patient involvement in research]
*2016, [https://www.youtube.com/watch?v=0SnJy5AOSd8/ Video of CDC Grand Rounds 16-Feb - Chronic Fatigue Syndrome: Advancing Research and Clinical Education]
*2016, [https://www.youtube.com/watch?v=hRdn4A2SGic/ Video of CDC Beyond the Data – Chronic Fatigue Syndrome: Advancing Research and Clinical Education]
*2016, [http://www107.zippyshare.com/v/GQFSakcm/file.html Audio recording of CDC Grand Rounds event February 16]
*2016, [http://www.meaction.net/2016/02/16/transcripts-and-slides-from-dr-naths-talk-on-nih-study/ Transcripts and slides from Dr Nath's talk on NIH study]
*2016, [http://www.cdc.gov/cdcgrandrounds/archives/2016/february2016.htm Chronic Fatigue Syndrome: Advancing Research and Clinical Education]
*2016, [http://www.cortjohnson.org/blog/2016/02/16/three-pronged-nih-mecfs-study-sets-treatments-as-ultimate-goal/ Three Pronged NIH ME/CFS Study Sets Treatments as Ultimate Goal]
*2016, [http://www.cortjohnson.org/blog/2016/02/09/the-nih-clinical-center-study-for-chronic-fatigue-syndrome-mecfs-the-good-the-bad-and-the-just-plain-weird/ The NIH Clinical Center Study for Chronic Fatigue Syndrome (ME/CFS): the Good, the Bad and the Just Plain Weird]

==See also==
*[[National Institutes of Health]]
*[[Ian Lipkin]]
*[[Anthony Komaroff]]
*[[Charles Lapp]]
*[[Elizabeth Unger]]
*[[Avindra Nath]]

==References==
<references/>

MEpedia:Contents

2015-12-06T04:12:04Z

Beth:

{{Cleanup | reason=Help us figure out how to organize content better (see discussion page) | date=November 2015}}

'''Welcome to MEpedia'''

We are co-creating a knowledge base on the history, science and medicine of ME and CFS. MEpedia.org is a project of #[[MEAction]] and the patient community.

==Please Contribute==
You can create pages, write content, add links/citations, fact-check, or even just fix typos. Get involved and help the patient community identify all of the best and most important resources for our disease and its research, treatment and history. Start now, read [[How To Contribute]]. Please also join [http://my.meaction.net/local_chapters/mepedia our group] of authors and editors.

==A note on ME v. CFS==

We have separate pages for [[Myalgic Encephalomyelitis]], [[ME/CFS]] and [[Chronic Fatigue Syndrome]] as well as [[SEID]]. The convention is that the terminology used in an ME-pedia article should match the terminology used in the underlying source. Where there is a tension between the term used in the source and the definition (e.g., ME defined by the [[Oxford criteria]] or CFS defined by the [[Canadian Consensus Criteria]]), it may be useful for clarity to mention the definition used.

==The Disease==

'''Infectious agents:''' [[Babesia]], [[Bartonella]], [[Borna Disease Virus]], [[Coxsackie A]], [[Coxsackie B]], [[cytomegalovirus]], [[enterovirus]], [[Epstein barr virus]], [[H1N1]], [[Herpesvirus]], [[HHV-6]], [[HHV-7]], [[HSV-1]], [[HSV-2]], [[influenza]], [[Parvovirus B-19]], [[Q Fever]], [[Ross River Virus]]

'''Triggers and risk factors:''' [[Viral onset]] [[Trauma]] [[Pregnancy]] [[Menstrual cycle]] [[Stress]] [[Vaccine]] [[Toxic exposure]] [[Candidiasis]] [[Mold]] [[Epidemiology]]

'''Signs and symptoms:''' [[Orthostatic intolerance]] [[Ataxia]] [[Cognitive dysfunction]] [[Postural orthostatic tachycardia]] [[Neurally mediated hypotension]] [[Sleep disturbance]] [[Fatigue]] [[Post-exertional malaise]] [[Nonepileptic seizure]] [[Seizure]] [[Migraine]] [[Muscle fatigability]] [[Food intolerance]] [[Optical dysfunction]]

'''Medical hypotheses:''' [[Methylation cycle hypothesis]] [[Amygdala hypothesis]] [[Hygiene hypothesis]] [[Viral onset hypothesis]] [[Microbiome hypothesis]] [[Fatty acid hypothesis]] [[Patricia Kane protocol]] [[Ken Lassesen's model]] [[Autoimmunity Hypothesis]]

'''Body systems:''' [[Nervous system]] [[HPA axis]] [[Brain]] [[Spinal cord]] [[Neuroinflammation]] [[Microglia]] [[Leaky brain]] [[Glutamate excitotoxicity]] [[Central sensitization]] [[Gastrointestinal system]] [[Microbiome]] [[Leaky gut]] [[Immune system]] [[Mucosal immune system]] [[B cell]] [[Natural killer cell]] [[Macrophage]] [[Cytokines]] [[IL-2]] [[interferon]] [[IL-10]] [[IL-1]] [[IL-18]] [[IL-17]] [[Tumor necrosis factors]] [[Ribonuclease L]] [[Antibody]] [[Autoantibody]] [[Cardiovascular system]] [[Blood]]

'''Tests:''' [[Cardiopulmonary exercise test]] [[Two day exercise test]] [[Erythrocyte sedimentation rate]] [[C reactive protein]] [[Brain imaging]] [[MRI]] [[qEEG]] [[SPECT]] [[Exercise]] [[Tilt Table]]

'''Citizen science:''' [[23andMe]] [[UBiome]] [[American Gut]] [[Mendus]] [[Any Treatment]] [[Phoenix Rising]]

'''Biochemistry and cell biology:''' [[Methylation cycle]] [[Citric acid cycle]] [[Mitochondria]] [[D lactate]] [[Lactic acid]] [[Nitric oxide]] [[Glutathione]] [[glucocorticoid]] [[endocannabinoid]] [[Histamine]] [[Tyrosine]] [[Phenylalanine]]

'''Nutrients:''' [[Vitamin D]] [[Vitamin C]] [[Copper]] [[Folate]] [[B12]] [[B6]] [[B2]] [[Deadlock quartet]] [[TMG]] [[Sam-e]] [[L-carnitine]] [[Zinc]] [[Magnesium]]

'''Neurotransmitters and hormones''': [[Neurotransmitters]] [[Serotonin]] [[Acetylcholine]] [[Dopamine]] [[Norepinephrine]] [[Epinephrine]] [[Melatonin]] [[Histamine]] [[Oxytocin]] [[Vasopressin]] [[Glutamate]] [[Hormones]] [[Cortisol]] [[Prostaglandins]] [[glucocorticoid]] [[progesterone]] [[estrogen]] [[testosterone]] [[estriadol]] [[calicitriol]] [[calcidiol]]

==Names & Definitions==
'''Names:''' [[Myalgic Encephalomyelitis]] [[Chronic Fatigue Syndrome]] [[ME/CFS]] [[Systemic Exertion Intolerance Disease]]
[[Chronic epstein barr]]

'''Related conditions:''' [[Chronic lyme disease]] [[Mold illness]] [[Biotoxin illness]] [[Environmental illness]] [[Multiple Chemical Sensitivity]] [[Gulf War Illness]] [[Mast cell activation disorder]] [[Mastocytosis]] [[Ehlers Danlos Syndrome]] [[Fibromyalgia]] [[Small intestine bacterial overgrowth]] [[Lactic acidosis]] [[Autoimmune disease]] [[Cancer]] [[Thyroid disease]] [[Non-Hodgkin's lymphoma]] [[Multiple Sclerosis]] [[Dysautonomia]]

'''Definitions:''' [[Definitions of ME and CFS]] [[Canadian Consensus Criteria]] [[International Consensus Criteria]] [[Oxford criteria]] [[Fukuda criteria]] [[Holmes criteria]] [[Ramsay definition]] [[London criteria]] [[Nightingale definition]]

==Treatment==
'''Supplements:''' [[Probiotics]] [[AHCC]] [[CoQ10]] [[MitoQ]] [[PrescriptAssist]] [[Mutaflor]] [[GcMAF]] [[Colostrum]] [[Transfer factors]] [[Fish oil]] [[EPA]] [[DHA]]

'''Antivirals:''' [[Valgancyclovir]] [[Famciclovir]] [[Valaciclovir]] [[Acyclovir]]

'''Immunomodulators and immunostimulants:''' [[Ampligen]] [[Low dose naltrexone]] [[Equilibrant]] [[Intravenous immunoglobulin]] [[Staphylococcal vaccine]] [[Immunovir]] [[medicinal mushrooms]]

'''Anti-inflammatory drugs:'''

'''Other drug treatments:''' [[Rituximab]] [[Prednisone]]

'''Diets:''' [[Vegan diet]] [[Vegetarian diet]] [[Paleo diet]] [[Ketogenic diet]] [[GAPS diet]] [[Specific carbohydrate diet]]

'''Uncategorized interventions:''' [[Mold avoidance]] [[Fasting]] [[Chelation]] [[Fecal matter transplant]] [[Helminth therapy]] [[Pacing]] [[Energy envelope]] [[Dark chocolate]] [[Medical marijuana]] [[Hyperbaric oxygen]] [[Ozone]] [[Altitude]] [[Coffee enema]] [[Exercise]] [[Faecal bacteriotherapy]]

'''Clinical Doctors, USA:''' [[Lucinda Bateman]] [[Derek Enlander]] [[Nancy Klimas]] [[Courtney Craig]] [[Daniel Peterson]] [[Phillipe Bottello]] [[John Chia]] [[Jacob Teitelbaum]]

'''Clinical Doctors, UK:''' [[Sarah Myhill]] [[William Weir]] [[Nigel Speight]] [[Peter Behan]] [[Charles Shepherd]] [[Gabrielle Murphy]] [[Amolak Bansal]]

'''Clinical Doctors, Germany:''' [[Anna Dorothea Hoeck]] [[Carmen Scheibenbogen]]

'''Clinical Doctors, Belgium:''' [[Kenny de Meirleir]]

'''Clinical Doctors, South Africa:''' [[Cecile Jadin]]

'''Clinical Doctors, Sweden:''' [[Carl-Gerhard Gottfries]]

==Research==

[[Notable Studies]]

''' Research initiatives USA:''' [[Open Medicine Foundation]] [[Chronic Fatigue Initiative]] [[Stanford ME/CFS Initiative]] [[Solve ME/CFS]] [[Microbe Discovery Project]] [[Bateman Horne Center]] [[Workwell Foundation]] [[Center for Infection & Immunity]]

''' Researchers USA:''' [[Ronald Davis]] [[Jarred Younger]] [[Alan Light]] [[Andreas Kogelnik]] [[Jose Montoya]] [[David Bell]] [[Mady Hornig]] [[Eric Schadt]] [[Ian Lipkin]] [[John Chia]] [[Rosemary Underhill]] [[Suzanne Vernon]] [[David Berg]] [[Nancy Klimas]] [[Dane Cook]] [[Staci Stevens]] [[Mark VanNess]] [[Christopher Snell]] [[Zaher Nahle]] [[Rich Van Konyenburg]] [[Judy Mikovits]]

''' Research initiatives Europe:''' [[ME Research UK]] [[Cure ME]] [[Invest in ME]] [[UK CFS/ME Collaborative]] [[Invest in ME Conference]] [[Ramsay Research Fund]] [[European ME Research Group]]

''' Researchers UK:''' [[Melvin Ramsay]] [[Donald Acheson]] [[Gordon Parish]] [[Jonathan Kerr]] [[Amolak Bansal]] [[Julia Newton]] [[Elizabeth Dowsett]] [[Simon Carding]] [[James Mowbray]] [[John Richardson]] [[Luis Nacul]] [[Derek Pheby]] [[Jonathan Edwards]] [[Geraldine Cambridge]]

''' Researchers Australia:''' [[Elaine DeFreitas]] [[Sonya Marshall-Gradisnik]] [[Donald Staines]]

''' Researchers Germany:''' [[Carmen Scheibenbogen]]

''' Researchers Norway:''' [[Olav Mella]] [[Øystein Fluge]]

''' Researchers Canada:''' [[Byron Hyde]]

==Psychological Paradigm==
'''Psychological paradigm, mind-body approaches and related interventions:''' [[PACE trial]] [[graded exercise therapy]] [[cognitive behavioral therapy]] [[biopsychosocial]] [[deconditioning]] [[Mickel therapy]] [[Lightning process]] [[Gupta programme]] [[Psychoneuroimmunology]] [[Meditation]] [[Bodily distress syndrome]] [[Functional somatic syndrome]] [[Psychosomatic illness]] [[Neurasthenia]] [[Medically unexplained symptoms]]

'''Psychological paradigm proponents:''' [[Simon Wessely]] [[Michael Sharpe]] [[Peter White]] [[Trudie Chalder]] [[Rona Moss-Morris]] [[Jessica Bavinton]] [[Esther Crawley]]

'''Psychological paradigm critics:''' [[James Coyne]] [[Keith Laws]] [[David Tuller]] [[Ronald Davis]] [[Bruce Levin]] [[Arthur Reingold]] [[Jonathan Edwards]] [[Leonard Jason]] [[Ellen Goudsmit]]

==Politics, Government & Insurance==
'''United States:''' [[Institute of Medicine report]] [[Pathways to prevention report]] [[Trans-NIH Working Group]] [[National Institutes of Health]] [[Centers for Disease Control & Prevention]] [[UNUM]]

'''United Kingdom:''' [[National Institute for Health and Care Excellence]] [[National Health Service]] [[Science Media Centre]] [[UNUM]]

[[ME Around the World]] [[Belgium]] [[France]] [[Germany]] [[Spain]] [[Italy]] [[United Kingdom]] [[Ireland]] [[Norway]] [[Denmark]] [[Sweden]] [[Finland]] [[United States]] [[Canada]]

==History==

'''Outbreaks:''' [[List of outbreaks]] [[Incline village]] [[Lyndonville]] [[Akureryi]] [[Los Angeles]] [[Royal Free Hospital]] [[Dalston]] [[Adelaide]]

'''Deceased patients:''' [[Sophia Mirza]] [[Vanessa Li]] [[Lynn Gilderdale]] [[Emily Collingridge]] [[Chardale Dotson Irvine]]

==Patient Advocacy==

'''Patient Groups:''' #[[MEAction]] [[ME Association]] [[Tymes Trust]] [[Irish ME/CFS Association]] [[ME Advocacy]] [[Change For M.E. Change For Us]]

'''Notable patients:''' [[Karina Hansen]] [[Joanne]] [[Sophia Mirza]] [[Lynn Gilderdale]] [[Emily Collingridge]] [[Whitney Dafoe]] [[Tom Kindlon]] [[Graham McPhee]] [[Jennie Spotila]] [[Laura Hillenbrand]] [[Martine McCutcheon]] [[Naomi Whittingham]] [[Jane Colby]] [[Countess of Mar]] [[Brian Vastag]] [[Jennifer Brea]] [[Ryan Prior]] [[Hillary Johnson]] [[Julie Rehmeyer]] [[Leonard Jason]] [[Charles Shepherd]] [[Nasim Marie Jafry]] [[Ken Lassesen]] [[Cort Johnson]] [[Valerie Eliot Smith]] [[Doctor Speedy]] [[Tanya Marlow]] [[Deborah Waroff]] [[Beth Mazur]] [[Catherine Hale]] [[Stuart Murdoch]] [[Mary Schweitzer]] [[Toni Bernhard]] [[Frank Twisk]]

'''Notable healthy advocates:''' [[Angela Kennedy]] [[Mary Dimmock]] [[Greg Crowhurst]] [[Malcolm Hooper]] [[Nicole Castillo]] [[Llewellyn King]]

'''Notable Quotes:''' [http://thoughtsaboutme.com/quotes/ Quotes]

==Journals, TV, Articles, Books, Film, Interviews, Blogs, Discussion Forums==

'''Journals:'''
[[The Lancet]]
[[The BMJ]]

'''TV:''' [[Sick and Tired]] [[Toxic Tiredness]]

'''Articles:''' [[List of news articles on ME and CFS]]

'''Books:'''
[[Plague]]
[[The State of Me]]
[[Love and Fatigue in America]]
[[Osler's Web]]
[[America's Biggest Cover-Up]]
[[Authors of our own misfortune]]
[[Reviving the Broken Marionette]]

'''Film:'''
[[What About ME]]
[[I Remember Me]]
[[Forgotten Plague]]
[[Canary in a Coal Mine]]
[[The Last Great Medical Cover Up]]
[[Invisible Illness - Stories of Chronic Fatigue Syndrome]]

'''Interviews:'''
[[ME/CFS Alert]] [[Science for Patients]] [[Unbroken' author's personal story of courage and resilience]]

'''Blogs:'''
[[Health Rising]]
[[Occupy CFS]]
[[MEAction]]
[[ME Advocacy]]
[[Courtney Craig]]
[[Cell Fatigue]]
[[CFS Patient Advocate]]
[[Constant F****** S***]]
[[ME Association]]
[[Onward Through the Fog]]
[[Nice Guidelines]]
[[Valerie Eliot Smith Blog]]
[[CFS Remission]]
[[About.com Health FMS/ME/CFS]]

'''Discussion Forums:'''
[[Phoenix Rising]]

== Open Letters ==
[[List of open letters from researchers]] [[List of open letters from patient advocates and advocacy organizations]]

MEpedia:Contents

2015-11-20T05:28:10Z

Beth:

'''Welcome to MEpedia.org'''

We aim to co-create a knowledge base on the history, science and medicine of ME and CFS.

MEpedia.org is a project of [http://meaction.net #MEAction]. Join [http://my.meaction.net/local_chapters/mepedia our group] of authors and editors.

== Where to start ==

=== Create a new article ===

To create a new article, simply search for the title of the article you wish to create. If a page does not already exist, you will see an option to create the page.

=== Start or expand a topic idea ===

You can also add a topic idea to list below below, being an article on one of the below topics, or expanding a stub article.

=== Correct our typos ===

You can also copyedit existing articles for typos and edit for clarity.

=== Check our references ===

You can make sure facts are properly cited and references are in correct format.

We aim to serve a general audience, a research audience, and a patient audience. All entries should be cited and make clear to distinguish what has and has not been established by peer-reviewed research findings. Articles should aim to provide both a general overview of a specific topic as well as discuss its implications or applications in ME and CFS.

== Formatting with MediaWiki ==

Writing articles on MEpedia requires familiarizing yourself with some of the basic formatting code used by MediaWiki, the software that powers both Wikipedia and MEpedia. Here are some articles that may be helpful:

* [https://www.mediawiki.org/wiki/Help:Formatting Formatting] (e.g, bold, italics, bullets)
* [https://www.mediawiki.org/wiki/Help:Links Creating internal and external links]

== Editorial guidelines ==

There is no formal editorial policy per se – that will likely evolve with time. When writing or editing each page it is helpful to consider:

* '''Accessibility''': What is the general information you would need to know to understand this topic? (What you are likely to find on a typical Wikipedia page)

* '''Specificity''': What are the relevant research findings, context, detail or applications of this topic to ME and CFS? (What you are unlikely to find on Wikipedia)

*'''Connection''': How does the topic relate and link to other topics (and MEpedia pages)?

* '''Source quality''': What is the quality of the source of the information? If it is a research study, was it a randomized double-blind trial? Was there a large sample size? What research definition(s) were used? Are there other studies that conflict with the results of that study? If a piece of information is without clear scientific support, it can still be included but must be clearly contextualized within the article as theory, anecdote or observation.

* '''Medical hypotheses''': If you want to go in-depth on a well-known hypothesis that may have only limited support in the scientific literature, consider starting a separate medical hypothesis page. For example: [[Methylation cycle hypothesis]] or [[Amygdala hypothesis]] or [[Mold hypothesis]]

*'''Naming conventions''': We have created separate pages for [[Myalgic Encephalomyelitis]], [[Chronic Fatigue Syndrome]], and [[ME/CFS]]. On all other pages the name used when citing scientific research is the name(s) the authors used in their study. The diagnostic criteria used can always be determined by looking at the original article. In general, it is not necessary to explain that the Fukuda criteria were used as the most common criteria, however it may be useful to describe when a study used either the Canadian Consensus Criteria, the Oxford Criteria, or another less used criteria, particularly if it is helpful for contextualizing the results of the study, or when studies that used different criteria have conflicting results.

== Topic ideas ==

'''Here are some ideas of articles that need to be written (not remotely exhaustive!).''' Pages in red need to be started. Pages in blue are stub pages that need expanding.

'''Infectious agents:''' [[Herpesvirus]] [[Epstein barr virus]] [[cytomegalovirus]] [[HSV-1]] [[HSV-2]] [[influenza]] [[HHV-6]] [[HHV-7]] [[Coxsackie A]] [[Coxsackie B]] [[Babesia]] [[Bartonella]] [[enterovirus]] [[Parvovirus B-19]] [[Ross River Virus]] [[Borna Disease Virus]] [[Q Fever]] [[H1N1]]

'''Triggers and risk factors:''' [[Viral onset]] [[Trauma]] [[Pregnancy]] [[Menstrual cycle]] [[Stress]] [[Vaccine]] [[Toxic exposure]] [[Candidiasis]] [[Mold]] [[Epidemiology]]

'''Signs and symptoms:''' [[Orthostatic intolerance]] [[Ataxia]] [[Cognitive dysfunction]] [[Postural orthostatic tachycardia]] [[Neurally mediated hypotension]] [[Sleep disturbance]] [[Fatigue]] [[Post-exertional malaise]] [[Nonepileptic seizure]] [[Seizure]] [[Migraine]] [[Muscle fatigability]] [[Food intolerance]]

'''Body systems:''' [[Nervous system]] [[HPA axis]] [[Brain]] [[Spinal cord]] [[Neuroinflammation]] [[Microglia]] [[Leaky brain]] [[Glutamate excitotoxicity]] [[Central sensitization]] [[Gastrointestinal system]] [[Microbiome]] [[Leaky gut]] [[Immune system]] [[Mucosal immune system]] [[B cell]] [[Natural killer cell]] [[Macrophage]] [[Cytokines]] [[IL-2]] [[interferon]] [[IL-10]] [[IL-1]] [[IL-18]] [[IL-17]] [[Tumor necrosis factors]] [[Ribonuclease L]] [[Antibody]] [[Autoantibody]] [[Cardiovascular system]] [[Blood]]

'''Tests''': [[Cardiopulmonary exercise test]] [[Two day exercise test]] [[Erythrocyte sedimentation rate]] [[C reactive protein]] [[Brain imaging]] [[MRI]] [[SPECT]] [[Exercise]]

'''Names and related conditions:''' [[Myalgic Encephalomyelitis]] [[Chronic Fatigue Syndrome]] [[ME/CFS]] [[Systemic Exertion Intolerance Disease]]
[[Chronic epstein barr]] [[Chronic lyme disease]] [[Mold illness]] [[Biotoxin illness]] [[Environmental illness]] [[Multiple Chemical Sensitivity]] [[Gulf War Illness]] [[Mast cell activation disorder]] [[Mastocytosis]] [[Ehlers Danlos Syndrome]] [[Fibromyalgia]] [[Small intestine bacterial overgrowth]] [[Lactic acidosis]] [[Autoimmune disease]] [[Cancer]] [[Thyroid disease]] [[Non-Hodgkin's lymphoma]]

'''Definitions:''' [[Definitions of ME and CFS]] [[Canadian Consensus Criteria]] [[International Consensus Criteria]] [[Oxford criteria]] [[Fukuda criteria]] [[Holmes criteria]]

'''US Government''' [[Institute of Medicine report]] [[Pathways to prevention report]] [[Trans-NIH Working Group]]

'''Biochemistry and cell biology:''' [[Methylation cycle]] [[Citric acid cycle]] [[Mitochondria]] [[D lactate]] [[Lactic acid]] [[Nitric oxide]] [[Glutathione]] [[glucocorticoid]] [[endocannabinoid]] [[Histamine]]

'''Nutrients:''' [[Vitamin D]] [[Vitamin C]] [[Copper]] [[Folate]] [[B12]] [[B6]] [[B2]] [[Deadlock quartet]] [[TMG]] [[Sam-e]] [[L-carnitine]] [[Zinc]] [[Magnesium]]

'''Supplements:''' [[Probiotics]] [[AHCC]] [[CoQ10]] [[MitoQ]] [[PrescriptAssist]] [[Mutaflor]] [[GcMAF]] [[Colostrum]] [[Transfer factors]]

'''Antivirals:''' [[Valgancyclovir]] [[Famciclovir]] [[Valaciclovir]] [[Acyclovir]] [[Immunovir]]

'''Immuomodulators and immunostimulants:''' [[Ampligen]] [[Low dose naltrexone]] [[Equilibrant]] [[Intravenous immunoglobulin]] [[Staphylococcal vaccine]]

'''Anti-inflammatory drugs:'''

'''Other drug treatments:''' [[Rituximab]] [[Prednisone]]

'''Diets:''' [[Vegan diet]] [[Vegetarian diet]] [[Paleo diet]] [[Ketogenic diet]] [[GAPS diet]] [[Specific carbohydrate diet]]

'''Uncategorized interventions:''' [[Mold avoidance]] [[Fasting]] [[Chelation]] [[Fecal matter transplant]] [[Helminth therapy]] [[Pacing]] [[Energy envelope]] [[Dark chocolate]] [[Medical marijuana]] [[Hyperbaric oxygen]] [[Ozone]] [[Altitude]] [[Coffee enema]]

'''Hypotheses:''' [[Methylation cycle hypothesis]] [[Amygdala hypothesis]] [[Hygiene hypothesis]]

'''Outbreaks:''' [[Incline village]] [[Lydonville]] [[Akuyeri]] [[Los Angeles]] [[Royal Free Hospital]]

'''Notable patients:''' [[Karina Hansen]] [[Joanne]] [[Sophia Mirza]] [[Lynn Gilderdale]] [[Emily Collingridge]] [[Whitney Dafoe]] [[Tom Kindlon]] [[Graham McPhee]] [[Jennie Spotila]] [[Laura Hillenbrand]] [[Martin McCutcheon]] [[Naomi Whittingham]] [[Jane Colby]] [[Countess of Mar]] [[Brian Vastag]] [[Jennifer Brea]] [[Ryan Prior]] [[Hillary Johnson]] [[Julie Rehmeyer]] [[Leonard Jason]] [[Charles Shepherd]] [[Nasim Marie Jafry]] [[Ken Lassesen]]

'''Deceased patients''' [[Sophia Mirza]] [[Vanessa Li]] [[Lynn Gilderdale]] [[Emily Collingridge]] [[Chardale Dotson Irvine]]

'''Psychological paradigm, mind-body approaches and related interventions:''' [[PACE trial]] [[graded exercise therapy]] [[cognitive behavioral therapy]] [[biopsychosocial]] [[deconditioning]] [[Mickel therapy]] [[Lightning process]] [[Gupta programme]] [[Psychoneuroimmunology]] [[meditation]] [[Bodily distress syndrome]] [[Functional somatic syndrome]] [[Psychosomatic illness]] [[Neurasthenia]]

'''Psychological paradigm proponents''' [[Simon Wessely]] [[Michael Sharpe]] [[Peter White]] [[Trudie Chalder]] [[Rona Moss-Morris]] [[Jessica Bavinton]] [[Esther Crawley]]

'''Psychological paradigm critics''' [[James Coyne]] [[Keith Laws]] [[David Tuller]] [[Ronald Davis]] [[Bruce Levin]] [[Arthur Reingold]] [[Jonathan Edwards]] [[Leonard Jason]]

[[Exercise]]

'''Citizen science:''' [[23andMe]] [[UBiome]] [[American Gut]] [[Mendus]] [[Any Treatment]] [[Phoenix Rising]]

'''Books:''' [[Plague]] [[The State of Me]] [[Love and Fatigue in America]] [[Osler's Web]] [[America's Biggest Cover-Up]]

'''Films:''' [[What About ME]] [[I Remember Me]] [[Forgotten Plague]] [[Canary in a Coal Mine]] [[The Last Great Medical Cover Up]]

'''Notable TV segments''' [[Sick and Tired]]

'''Clinical Doctors:''' [[Sarah Myhill]] [[Lucinda Bateman]] [[Derek Enlander]] [[Kenny de Meirleir]] [[William Weir]] [[Nancy Klimas]] [[Courtney Craig]] [[Daniel Peterson]] [[Nigel Speight]] [[Peter Behan]] [[Charles Shepherd]] [[Anna Dorothea Hoeck]] [[Cecile Jadin]] [[Phillipe Bottello]]

'''Research initiatives:''' [[Invest in ME]] [[Open Medicine Foundation]] [[Chronic Fatigue Initiative]] [[Solve ME/CFS]] [[Microbe Discovery Project]] [[UK CFS/ME Collaborative]] [[Invest in ME Conference]]

''' Researchers:''' [[Ronald Davis]] [[Jarred Younger]] [[Alan Light]] [[Melvin Ramsay]] [[Judy Mikovits]] [[Amolak Bansal]] [[Julia Newton]] [[Andreas Kogelnik]] [[Jose Montoya]] [[David Bell]] [[Mady Hornig]] [[Eric Schadt]] [[Ian Lipkin]] [[Elizabeth Dowsett]] [[Byron Hyde]] [[Elaine Defreitas]] [[David Berg]] [[John Chia]] [[Sonya Marshall-Gradisnik]] [[Donald Staines]] [[Carmen Scheibenbogen]] [[Simon Carding]]

'''Patient Groups''' [[ME Association]] [[Tymes Trust]] [[Irish ME/CFS Association]]

== Media Wiki articles ==
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* [//www.mediawiki.org/wiki/Special:MyLanguage/Manual:FAQ MediaWiki FAQ]
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