Vascular endothelial growth factor

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Vascular Endothelial Growth Factor (VEGF) or Vascular Endothelial Growth Factor A (VEGF-A) is a signal protein produced by cells that stimulates blood vessel formation (vasculogenesis and angiogenesis).[1] Vascular Endothelial Growth Factor was originally known as vascular permeability factor (VPF).

The VEGF family help maintain blood vessel and lymphatic systems.[1]

ME/CFS[edit | edit source]

Landi et al. (2016) found lower levels of VEGF, IL-7 and IL-16 in 100 long-term ME/CFS patients compared to controls but studies by Horning et al. (2015) and Montoya et al. (2017) did not find this statistically significant.[2][3]

Notable studies[edit | edit source]

  • 2016, Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]