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Vance Spence
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[[File:Vance Spence.png|200px|thumb|right|Source:25%MEGroup]] '''Vance A. Spence,''' Ph.D., was a Principal Clinical Scientist responsible for vascular services and research. In 1997, he returned from an early retirement due to contracting [[myalgic encephalomyelitis]] (ME)<ref name=":1">{{Cite web|url=https://25megroup.org/patrons-trustees-advisers | title = Patrons, Trustees, Advisers|website=25% M.E. Group|language=en-US|access-date=2020-02-19}}</ref> to become an Honorary Senior Research Fellow in the Department of Medicine at the University of Dundee, Scotland, with the objective of stimulating research into the cause of [[myalgic encephalomyelitis]] (ME) and [[chronic fatigue syndrome]] (CFS).<ref>{{Cite web|url=http://www.investinme.org/IIMEC2.shtml#presenters | title = Invest in ME Research - IIMEC2 | website = [[Invest in ME Research]]|access-date=2020-02-19}}</ref> He is especially interested in the role of [[inflammation]], oxidative stress, and [[acetylcholine]] in these illnesses. Dr Spence helped found and serves as Chairman of [[ME Research UK]], a research group.<ref>{{Cite web|url=http://www.meresearch.org.uk/about-us/meet-the-team/ | title = Meet the team {{!}} ME Research UK|language=en-US|access-date=2020-02-19}}</ref> Additionally, he helped found MERGE, the ME biomedical research charity and serves as Scientific Advisor for the [[25 Percent ME Group]], a patient group for the severe [[myalgic encephalomyelitis|ME]] patient.<ref name=":1" /> ==Talks and interviews== *01 May 2007, Speaker at Day 1 of the 2nd Invest in ME International ME Conference; talk title - ''Biomedical Research into ME/CFS: where does it go from here''<ref name=":0">{{Cite web|url=http://www.investinme.org/IIMEC2.shtml#agenda | title = Invest in ME Research - IIMEC2 | website = [[Invest in ME Research]]|access-date=2020-02-19}}</ref> - [https://www.youtube.com/watch?v=hLCNhEI8tPc (Video)] *02 May 2007, Speaker at Day 2 of the 2nd Invest in ME International ME Conference; talk title - ''Biomedical Research into ME/CFS: where does it go from here''<ref name=":0" /> - [https://www.youtube.com/watch?v=UZCNYbzaT28 (Video)] *2007, Speaker at the Eighth International [[IACFSME]] Conference Agenda on "Inflammation and Arterial Stiffness in Patients with Chronic Fatigue Syndrome"<ref>{{Cite web|url=https://www.iacfsme.org/Conferences/2007-Fort-Lauderdale/Eighth-International-Conference-Agenda-Professiona.aspx | title = Home|website=iacfsme.org|access-date=2020-02-19}}</ref> *2014, Speaker at the [[ME Research UK]] Stormont Parliament meeting, ‘ME in Northern Ireland: practice and research priorities’; talk title - “The science of ME/CFS: What do we know?”<ref>{{Cite web|url=http://www.meresearch.org.uk/meeting-at-stormont-parliament/ | title = Meeting at Stormont Parliament {{!}} ME Research UK|language=en-US|access-date=2020-02-19}}</ref> ==Notable studies== *2004, [http://www.clinsci.org/content/106/2/183.full-text.pdf Peripheral cholinergic function in humans with chronic fatigue syndrome, Gulf War syndrome and with illness following organophosphate exposure]<ref name="Khan, 2004" /> *2004, [https://www.ncbi.nlm.nih.gov/pubmed/15041034 Acetylcholine mediated vasodilatation in the microcirculation of patients with chronic fatigue syndrome]<ref name="Spence, 2004" /> *2005, [http://www.sciencedirect.com/science/article/pii/S0891584905002121 Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms]<ref name="Kennedy, 2005" /> *2008, [http://www.clinsci.org/content/114/8/561 Low-grade inflammation and arterial wave reflection in patients with chronic fatigue syndrome]<ref name="Spence, 2008" /> ==See also== *[[25 Percent ME Group]] *[[ME Research UK]] ==References== <references> <ref name="Spence, 2008">{{Citation | last1 = Spence | first1 = Vance A. | authorlink1 = Vance Spence | last2 = Kennedy | first2 = Gwen | authorlink2 = | last3 = Belch | first3 = Jill J. F. | authorlink3 = | last4 = Hill | first4 = Alexander | authorlink4 = | last5 = Khan | first5 = Faisel | authorlink5 = Faisel Khan | title = Low-grade inflammation and arterial wave reflection in patients with chronic fatigue syndrome | journal = Clinical Science | volume = 114 | issue = 8 | page = 561-566 | date = 2008 | pmid = | doi = 10.1042/CS20070274 }}</ref> <ref name="Khan, 2004">{{Citation | last1 = Khan | first1 = Faisel | authorlink1 = Faisel Khan | last2 = Kennedy | first2 = Gwen | authorlink2 = | last3 = Spence | first3 = Vance A. | authorlink3 = Vance Spence | last4 = Newton | first4 = David J. | authorlink4 = | last5 = Belch | first5 = Jill J. F. | authorlink5 = | title = Peripheral cholinergic function in humans with chronic fatigue syndrome, Gulf War syndrome and with illness following organophosphate exposure | journal = Clinical Science | volume = 106 | issue = 2 | page = 183-189 | date = 2004 | pmid = | doi = 10.1042/CS20030246 }}</ref> <ref name="Kennedy, 2005">{{Citation | last1 = Kennedy | first1 = Gwen | authorlink1 = | last2 = Spence | first2 = Vance A. | authorlink2 = Vance Spence | last3 = McLaren | first3 = Margaret| authorlink3 = | last4 = Hill | first4 = Alexander | authorlink4 = | last5 = Underwood | first5 = Christine | authorlink5 = | last6 = Belch | first6 = Jill J. F. | authorlink6 = | title = Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms | journal = Free Radical Biology and Medicine | volume = 39 | issue = 5 | page = 584–589 | date = 2005 | pmid = | doi = 10.1016/j.freeradbiomed.2005.04.020 }}</ref> <ref name="Spence, 2004">{{Citation | last1 = Spence | first1 = VA | authorlink1 = Vance Spence | last2 = Khan | first2 = F | authorlink2 = Faisel Khan | last3 = Kennedy | first3 = G | authorlink3 = | last4 = Abbot | first4 = NC | authorlink4 = | last5 = Belch | first5 = JJ | authorlink5 = | title = Acetylcholine mediated vasodilatation in the microcirculation of patients with chronic fatigue syndrome | journal = Prostaglandins, leukotrienes, and essential fatty acids | volume = 70 | issue = 4 | page = 403-7 | date = 2004 | pmid = | doi = 10.1016/j.plefa.2003.12.016 }}</ref> </references> [[Category:Researchers]] [[Category:UK researchers]] [[Category:People with ME, CFS, and/or FMS]]
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