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Vaccine
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===Subunit, recombinant, polysaccharide and conjugate vaccines=== These vaccines do not contain the whole virus or pathogen, they may contain just particular pieces, e.g. a protein, sugar or part of the shell of the pathogen. This creates a very strong targetted immune response.<ref name="hhs-types" /> Recombinant vaccines have been around since the 1970s and use DNA technology to combine two or more sources, e.g., antigen in the hepatitis B vaccine is a hepatitis B virus protein produced by yeast cells into which the genetic code for the viral protein has been inserted into. These may use virus-like particles (VLP) from the shell of a virus to cause immunity without the risk of infection.<ref name="niaid-types" /> Subunit, recombinant, polysaccharide and conjugate viruses are suitable for people with '''weakened immune systems''', chronic illness or other long-term health conditions as well as the general population. Examples include the current Hib (haemophilus influenzae type b) vaccines, [[HPV]] vaccines, and [[hepatitis B vaccine]].<ref name="hhs-types" /> Several booster shots may be needed.<ref name="hhs-types" />
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