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{{Cleanup | reason=Help us figure out how to organize content better (see discussion page) | date=November 2015}} '''Welcome to MEpedia''' We are co-creating a knowledge base on the history, science and medicine of ME and CFS. MEpedia.org is a project of #[[MEAction]] and the patient community. Read more [[MEpedia:About|about MEpedia and its principles]]. ==Please Contribute== You can create pages, write content, add links/citations, fact-check, or even just fix typos. Get involved and help the patient community identify all of the best and most important resources for our disease and its research, treatment and history. Start now, read [[How to contribute]]. Please also [http://my.meaction.net/local_chapters/mepedia join our group of authors and editors]. ==A note on ME v. CFS== We have separate pages for [[Myalgic Encephalomyelitis]], [[ME/CFS]] and [[Chronic Fatigue Syndrome]] as well as [[SEID]]. The convention is that the terminology used in an ME-pedia article should match the terminology used in the underlying source. Where there is a tension between the term used in the source and the definition (e.g., [[ME]] defined by the [[Oxford criteria]] or [[CFS]] defined by the [[Canadian Consensus Criteria]]), it may be useful for clarity to mention the definition used. ==The Disease== '''Infectious agents:''' [[Babesia]], [[Bartonella]], [[Borna Disease Virus]], [[Chlamydia pneumoniae]], [[Coxsackie A]], [[Coxsackie B]], [[cytomegalovirus]], [[echovirus]], [[enterovirus]], [[Epstein barr virus]], [[H1N1]], [[Herpesvirus]], [[Human herpesvirus 6]], [[HHV-7]], [[Herpes simplex virus#HSV-1|HSV-1]], [[Herpes simplex virus#HSV-2|HSV-2]], [[influenza]], [[parvovirus B19]], [[Q Fever]], [[Ross River Virus]] '''Triggers and risk factors:''' [[Blood donation]], [[Candidiasis]], [[Causes of death]], [[Epidemiology]], [[Menstrual cycle]], [[Mold]], [[Pediatric]], [[Pregnancy]], [[Stress]], [[Toxic exposure]], [[Trauma]], [[Vaccine]], [[Viral onset]] '''Signs and symptoms:''' [[Ataxia]], [[Cognitive dysfunction]], [[Fatigue]], [[Food intolerance]], [[Irritable bowel syndrome]], [[Migraine]], [[Muscle fatigability]], [[Neurally mediated hypotension]], [[Nonepileptic seizure]], [[Optical dysfunction]], [[Orthostatic intolerance]], [[Post-exertional malaise]], [[Postural orthostatic tachycardia]], [[Seizure]], [[Sleep disturbance]] '''Medical hypotheses:''' [[Amygdala hypothesis]], [[Autoimmunity Hypothesis]], [[Fatty acid hypothesis]], [[Hygiene hypothesis]], [[Infectious disease hypothesis]], [[Ken Lassesen's model]], [[Methylation cycle hypothesis]], [[Microbiome hypothesis]], [[Mold hypothesis]], [[Patricia Kane protocol]], [[Vagus nerve hypothesis]], [[Viral onset hypothesis]] [[Hypercoagulation hypothesis]] '''Body systems:''' [[Antibody]], [[Autoantibody]], [[Blood]], [[Brain]], [[B cell]], [[Central sensitization]], [[Cytokine]], [[Chemokine]], [[Cardiovascular system]], [[Gastrointestinal system]], [[Glutamate excitotoxicity]], [[HPA axis]], [[Immune system]], [[IL-1]], [[IL-2]], [[IL-10]], [[IL-16]], [[IL-17]], [[IL-18]], [[interferon]], [[Leaky brain]], [[Leaky gut]], [[Macrophage]], [[Microglia]], [[Microbiome]], [[Mucosal immune system]], [[Nervous system]], [[Natural killer cell]], [[Neuroinflammation]], [[Ribonuclease L]], [[Spinal cord]], [[Tumor necrosis factors]], [[VEGF]] '''Tests:''' [[Brain imaging]], [[Cardiopulmonary exercise test]], [[CellTrend diagnostic test]], [[C reactive protein]], [[Erythrocyte sedimentation rate]], [[Exercise]], [[MRI]], [[qEEG]], [[SPECT]], [[Tilt Table]], [[Two day exercise test]] '''Citizen science:''' [[23andMe]], [[American Gut]], [[Any Treatment]], [[Mendus]], [[Phoenix Rising]], [[UBiome]] '''Biochemistry and cell biology:''' [[ATP]], [[Cellular respiration]], [[Citric acid cycle]], [[D lactate]], [[Endocannabinoid]], [[Glucocorticoid]], [[Glutathione]], [[Histamine]], [[Methylation cycle]], [[Mitochondrion]], [[Nitric oxide]], [[Oxidative phosphorylation]], [[Phenylalanine]], [[Tyrosine]] '''Nutrients:''' [[Copper]], [[Deadlock quartet]], [[Folate]], [[L-carnitine]], [[Magnesium]], [[Sam-e]], [[TMG]], [[Vitamin B2]], [[Vitamin B6]], [[Vitamin B12]], [[Vitamin C]], [[Vitamin D]], [[Zinc]] '''Neurotransmitters and hormones''': [[Acetylcholine]], [[Calicitriol]], [[Calcidiol]], [[Cortisol]], [[Dopamine]], [[Estriadol]], [[Epinephrine]], [[Estrogen]], [[Glucocorticoid]], [[Glutamate]], [[Histamine]], [[Hormones]], [[Melatonin]], [[Neurotransmitters]], [[Norepinephrine]], [[Oxytocin]], [[Progesterone]], [[Prolactin]], [[Prostaglandins]], [[Serotonin]], [[Testosterone]], [[Vasopressin]] ==Names & Definitions== '''Names:''' [[Myalgic Encephalomyelitis]], [[Chronic Fatigue Syndrome]], [[ME/CFS]], [[Systemic Exertion Intolerance Disease]], [[Chronic Fatigue Immune Deficiency Syndrome]], [[Chronic epstein barr]], [[Neuro-Inflammatory and Oxidative Fatigue]] '''Related conditions:''' [[Chronic lyme disease]], [[Mold illness]], [[Biotoxin illness]], [[Environmental illness]], [[Multiple Chemical Sensitivity]], [[Gulf War Illness]], [[Mast cell activation disorder]], [[Mastocytosis]], [[Ehlers Danlos Syndrome]], [[Fibromyalgia]], [[Small intestine bacterial overgrowth]], [[Lactic acidosis]], [[Autoimmune disease]], [[Cancer]], [[Thyroid disease]], [[Non-Hodgkin's lymphoma]], [[Multiple Sclerosis]], [[Dysautonomia]] '''Definitions:''' [[Definitions of ME and CFS]], [[Canadian Consensus Criteria]], [[International Consensus Criteria]], [[Oxford criteria]], [[Fukuda criteria]], [[Holmes criteria]], [[Empirical definition]], [[Ramsay definition]], [[London criteria]], [[Nightingale definition]] '''Acronyms:''' [[List of acronyms]] ==Potential treatments== '''Supplements:''' [[Probiotics]], [[AHCC]], [[CoQ10]], [[L-carnitine]], [[MitoQ]], [[NADH]], [[PrescriptAssist]], [[Mutaflor]], [[GcMAF]], [[Colostrum]], [[Transfer factors]], [[Fish oil]], [[EPA]], [[DHA]], [[Taurine]] '''Foods:''' [[Cocoa|Cocoa (Dark chocolate)]] '''Herbs:''' [[Medical marijuana]] '''Diets:''' [[Vegan diet]], [[Vegetarian diet]], [[Paleo diet]], [[Ketogenic diet]], [[GAPS diet]], [[Specific carbohydrate diet]] '''Antivirals:''' [[Valgancyclovir]], [[Famciclovir]], [[Valaciclovir]], [[Acyclovir]] '''Immunomodulators and immunostimulants:''' [[Ampligen]], [[Low dose naltrexone]], [[Equilibrant]], [[Intravenous immunoglobulin]], [[Staphylococcal vaccine]], [[Immunovir]], [[Medicinal mushrooms]], [[Interferon]] '''Anti-inflammatory drugs:''' '''Other drug treatments:''' [[Rituximab]], [[Prednisone]], [[Chelation]] '''Toxin avoidance/removal:''' [[Fasting]], [[Mold avoidance]], [[Coffee enema]] '''Uncategorized interventions:''' [[Fecal matter transplant]]/[[Faecal bacteriotherapy]], [[Helminth therapy]], [[Pacing]], [[Energy envelope]], [[Hyperbaric oxygen]], [[Ozone]], [[Altitude]], [[Exercise]] ==Doctors== '''Clinical Doctors, USA:''' [[Lucinda Bateman]];UT [[Derek Enlander]];NY [[Nancy Klimas]];FL [[Courtney Craig]]; [[Daniel Peterson]];NV [[Phillipe Bottello]]; [[John Chia]];CA [[Jacob Teitelbaum]]; [[Richard Podell]];NJ [[Susan Levine]];CH [[Laura Black]];NC '''Clinical Doctors, UK:''' [[Sarah Myhill]], [[William Weir]], [[Nigel Speight]], [[Peter Behan]], [[Charles Shepherd]], [[Gabrielle Murphy]], [[Amolak Bansal]] '''Clinical Doctors, Germany:''' [[Anna Dorothea Hoeck]], [[Carmen Scheibenbogen]] '''Clinical Doctors, Belgium:''' [[Kenny de Meirleir]] '''Clinical Doctors, South Africa:''' [[Cecile Jadin]] '''Clinical Doctors, Sweden:''' [[Carl-Gerhard Gottfries]] '''Clinical Doctors, Italy:''' [[Umberto Tirelli]], [[Lorenzo Lorusso]], [[Eligio Pizzigallo]] ==Research== [[Notable Studies]] ''' Research initiatives USA:''' [[Open Medicine Foundation]] [[Chronic Fatigue Initiative]] [[Stanford ME/CFS Initiative]] [[Microbe Discovery Project]] [[Bateman Horne Center]] [[Workwell Foundation]] [[Center for Infection & Immunity]] [[Solve ME/CFS Initiative]] [[Simmaron Research]] ''' Researchers USA:''' [[Ronald Davis]] [[Jarred Younger]] [[Alan Light]] [[Kathleen Light]] [[Andreas Kogelnik]] [[Jose Montoya]] [[David Bell]] [[Mady Hornig]] [[Eric Schadt]] [[Ian Lipkin]] [[John Chia]] [[Rosemary Underhill]] [[Suzanne Vernon]] [[David Berg]] [[Nancy Klimas]] [[Dane Cook]] [[Staci Stevens]] [[Mark VanNess]] [[Christopher Snell]] [[Zaher Nahle]] [[Rich Van Konyenburg]] [[Judy Mikovits]] [[Paul Cheney]] [[Michael Van ElZakker]] [[Zaher Nahle]] [[Michael Zeineh]] ''' Research initiatives Europe:''' [[ME Research UK]] [[Cure ME]] [[Invest in ME]] [[UK CFS/ME Collaborative]] [[Invest in ME Conference]] [[Ramsay Research Fund]] [[European ME Research Group]] ''' Researchers UK:''' [[Melvin Ramsay]] [[Donald Acheson]] [[Gordon Parish]] [[Jonathan Kerr]] [[Amolak Bansal]] [[Julia Newton]] [[Elizabeth Dowsett]] [[Simon Carding]] [[James Mowbray]] [[John Richardson]] [[Luis Nacul]] [[Derek Pheby]] [[Jonathan Edwards]] [[Geraldine Cambridge]] [[George Davey Smith]] ''' Researchers Australia:''' [[Elaine DeFreitas]] [[Sonya Marshall-Gradisnik]] [[Donald Staines]] [[Michael Maes]] ''' Researchers Germany:''' [[Carmen Scheibenbogen]] ''' Researchers Norway:''' [[Olav Mella]] [[Øystein Fluge]] ''' Researchers Canada:''' [[Byron Hyde]] [[Patrick O. McGowan]] ==Psychological Paradigm== '''Psychological paradigm, mind-body approaches and related interventions:''' [[PACE trial]] [[graded exercise therapy]] [[cognitive behavioral therapy]] [[biopsychosocial]] [[deconditioning]] [[Mickel therapy]] [[Lightning process]] [[Gupta programme]] [[Psychoneuroimmunology]] [[Meditation]] [[Bodily distress syndrome]] [[Functional somatic syndrome]] [[Psychosomatic illness]] [[Neurasthenia]] [[Medically unexplained symptoms]] '''Psychological paradigm proponents:''' [[Simon Wessely]] [[Michael Sharpe]] [[Peter White]] [[Trudie Chalder]] [[Rona Moss-Morris]] [[Jessica Bavinton]] [[Esther Crawley]] [[Anthony Cleare]] [[Ben Goldacre]] '''Psychological paradigm critics:''' [[James Coyne]] [[Keith Laws]] [[David Tuller]] [[Ronald Davis]] [[Bruce Levin]] [[Arthur Reingold]] [[Jonathan Edwards]] [[Leonard Jason]] [[Ellen Goudsmit]] ==Primers== *[[Primer for doctors and researchers]] *[[Primer for patients]] *[[Primer for family, friends and care providers]] *[[Primer for science journalists]] ==Politics, Government & Insurance== '''United States:''' [[Institute of Medicine report]] [[Pathways to prevention report]] [[Trans-NIH Working Group]] [[National Institutes of Health]] [[Centers for Disease Control & Prevention]] [[UNUM]] '''United Kingdom:''' [[National Institute for Health and Care Excellence]] (England & Wales) [[National Health Service]] [[Science Media Centre]] [[UNUM]] [[NHS Scotland]] [[Secret files]] '''ME Around the World:''' [[Belgium]] [[France]] [[Germany]] [[Spain]] [[Italy]] [[United Kingdom]] [[Ireland]] [[Norway]] [[Denmark]] [[Sweden]] [[Finland]] [[United States]] [[Canada]] ==History== '''Outbreaks:''' [[List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks|List of outbreaks]] [[Incline village]] [[Lyndonville]] [[Akureyri]] [[Los Angeles]] [[Royal Free Hospital]] [[Dalston]] [[Adelaide]] [[Ayrshire]] '''Deceased patients:''' [[Sophia Mirza]] [[Vanessa Li]] [[Lynn Gilderdale]] [[Emily Collingridge]] [[Chardale Dotson Irvine]] '''Major developments/controversies:''' [[PACE trial]], [[XMRV]], [[Important events timeline]] ==Patient Advocacy== '''Patient Groups USA:''' #[[MEAction]], [[ME Advocacy]] '''Patient Groups UK:''' [[Change For M.E. Change For Us]], [[Norfolk & Suffolk ME]], [[ME Association]], [[Tymes Trust]], [[MEActionUK]], [[Forward-ME]], [[Hope 4 ME & Fibro NI]] [[Welsh Association of ME & CFS Support]] [[Sussex & Kent ME/CFS Society]] [[Association of Young People with ME]] [[Tyne & Wear ME/CFS Support Group]] '''Patient Groups Canada:''' [[National ME/FM Action Network]] [[May12th.org]] '''Patient Groups Ireland:''' [[Irish ME/CFS Association]] '''Patient Groups Italy:''' [[CFS Associazione Italiana onlus]], [[Associazione Malati CFS onlus]] '''Notable patients:''' [[Karina Hansen]], [[Joanne]], [[Sophia Mirza]], [[Lynn Gilderdale]], [[Emily Collingridge]], [[Whitney Dafoe]], [[Tom Kindlon]], [[Graham McPhee]], [[Jennie Spotila]], [[Laura Hillenbrand]], [[Martine McCutcheon]], [[Naomi Whittingham]], [[Jane Colby]], [[Countess of Mar]], [[Brian Vastag]], [[Jennifer Brea]], [[Ryan Prior]], [[Hillary Johnson]], [[Julie Rehmeyer]], [[Leonard Jason]], [[Charles Shepherd]], [[Nasim Marie Jafry]], [[Ken Lassesen]], [[Cort Johnson]], [[Valerie Eliot Smith]], [[Doctor Speedy]], [[Tanya Marlow]], [[Deborah Waroff]], [[Beth Mazur]], [[Catherine Hale]], [[Stuart Murdoch]], [[Mary Schweitzer]], [[Toni Bernhard]], [[Frank Twisk]], [[Steven Lubet]], [[Giada Da Ros]], [[Roberta Pelletta]] [[Carol Head]] '''Notable healthy advocates:''' [[Angela Kennedy]], [[Mary Dimmock]], [[Greg Crowhurst]], [[Malcolm Hooper]], [[Nicole Castillo]], [[Llewellyn King]], [[Erica Verrillo]], [[Tom Whittingham]], [[Mike Harley]] '''Notable Quotes:''' [http://thoughtsaboutme.com/quotes/ Quotes] ==Journals, TV, Articles, Books, Film, Interviews, Blogs, Discussion Forums== '''Journals:''' [[The Lancet]] [[Lancet Psychiatry]] [[The BMJ]] [[Journal of Chronic Fatigue Syndrome]] '''TV:''' [[Sick and Tired]] [[Toxic Tiredness]] '''Articles:''' [[List of news articles on ME and CFS]] '''Books:''' [[Plague]] [[The State of Me]] [[Love and Fatigue in America]] [[Osler's Web]] [[America's Biggest Cover-Up]] [[Authors of our own misfortune]] [[Reviving the Broken Marionette]] [[Why ME?]] [[Stanchi: Vivere con la Sindrome da Fatica Cronica]] [[Stanchi si diventa]] [[Frammenti di ME]] [[Encounters with the Invisible]] [[Chronic Fatigue Syndrome: A Treatment Guide]] [[Chronic Fatigue Syndrome: A Treatment Guide - 2nd Edition]] [[Severe ME/CFS: A Guide to Living]] [[Severe ME - Featuring: "Justice for Karina Hansen"]] [[Severe ME: Notes for Carers]] '''Film:''' [[What About ME]] [[I Remember Me]] [[Forgotten Plague]] [[Canary in a Coal Mine]] [[The Last Great Medical Cover Up]] [[Invisible Illness - Stories of Chronic Fatigue Syndrome]] [[Voices From the Shadows]] '''Interviews:''' [[ME/CFS Alert]] [[Science for Patients]] [[Unbroken' author's personal story of courage and resilience]] '''Blogs:''' [[Health Rising]] [[Occupy CFS]] [[MEAction]] [[ME Advocacy]] [[Courtney Craig]] [[Cell Fatigue]] [[CFS Patient Advocate]] [[Constant F****** S***]] [[ME Association]] [[Onward Through the Fog]] [[Nice Guidelines]] [[Valerie Eliot Smith Blog]] [[CFS Remission]] [[About.com Health FMS/ME/CFS]] [[Just ME]] [[ME/CFS Ghost]] '''Discussion Forums:''' [[Phoenix Rising]] [[CFSItalia]] [[MDJunction]] == [[Open Letters]] ==
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