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Tryptase alpha/beta 1
(section)
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==Hereditary alpha tryptasemia syndrome== Extra copies of the TPSAB1 gene is known as '''familial hypertryptasemia''' (FHT) or '''hereditary alpha tryptasemia''' (HβΊT or HAT) and is one of several possible causes for increased [[tryptase]] production.<ref name="Lyons2016">{{Cite journal | title = Hereditary Alpha Tryptasemia: Genotyping and Associated Clinical Features | date = 2018-08-01|url=https://www.sciencedirect.com/science/article/pii/S0889856118300298|journal=Immunology and Allergy Clinics of North America|volume=38|issue=3|pages=483β495 | last =Lyons | first = Jonathan J.|series=Mastocytosis|language=en|doi=10.1016/j.iac.2018.04.003|pmc=PMC6411063|pmid=30007465|issn=0889-8561}}</ref> HAT is common and often does not cause illness.<ref name="Lyons2016"/> '''Hereditary alpha tryptasemia syndrome''' (HATS) is a recently discovered multi-systemic illness involving an increased number of TPSAB1 genes with a cluster of symptoms similar to those found in [[mast cell activation syndrome|MCAS]]. {{See also|Hereditary alpha tryptasemia syndrome}} {{See also|Mast cell activation syndrome}}
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