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Toll-like receptor 4
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==Infection== [[Coxsackie B4]] triggers TLR4 on human pancreatic cells,<ref>{{Cite journal | title = Coxsackievirus B4-induced cytokine production in pancreatic cells is mediated through toll-like receptor 4 | date = Oct 2004|url=https://pubmed.ncbi.nlm.nih.gov/15452251/|journal=Journal of Virology|volume=78|issue=20|pages=11313β11320 | last = Triantafilou | first = Kathy | authorlink = | last2 = Triantafilou | first2 = Martha | authorlink2 = |doi=10.1128/JVI.78.20.11313-11320.2004|pmc=|pmid=15452251|access-date=|issn=0022-538X|quote=|via=}}</ref> TLR4 knock-out mice infected with [[Coxsackie B3]] showed reduced [[myocarditis]] and viral replication.<ref>{{Cite journal | title = IL-12 receptor beta 1 and Toll-like receptor 4 increase IL-1 beta- and IL-18-associated myocarditis and coxsackievirus replication | date = 2003-05-01|url=https://pubmed.ncbi.nlm.nih.gov/12707353/|journal=Journal of Immunology (Baltimore, Md.: 1950)|volume=170|issue=9|pages=4731β4737 | last = Fairweather | first=DeLisa | last2 = Yusung | first2 = Susan | last3 = Frisancho | first3 = Sylvia | last4 = Barrett | first4 = Masheka| last5 = Gatewood | first5 = Shannon | last6 = Steele | first6 = Ronelle | last7 = Rose | first7 = Noel R.|doi=10.4049/jimmunol.170.9.4731|pmid=12707353|issn=0022-1767}}</ref>
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