The Perrin Technique: Difference between revisions

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The '''Perrin technique''' is a bio-mechanical treatment consisting of lymphatic drainage, spinal and cranial osteopathy developed by UK-based osteopath [[Raymond Perrin]] for patients suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).<ref name=Perrin2010 />  
The '''Perrin technique''' is a bio-mechanical treatment consisting of lymphatic drainage, spinal and cranial osteopathy developed by UK-based osteopath [[Raymond Perrin]] for patients suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).<ref name="Perrin2010" />  


The Perrin technique is based on the hypothesis that the underlying cause of ME/CFS is impaired function of the lymphatic<ref>{{Cite book|title=The Perrin technique : how to beat chronic fatigue syndrome/ME|isbn=978-1-905140-12-1|url=https://www.worldcat.org/oclc/244652322|date=2007|publisher=Hammersmith|last=Perrin, Raymond N.|oclc=244652322|location=London}}</ref> and "glymphatic"<ref>{{Cite journal|last=Iliff|first=J. J.|last2=Wang|first2=M.|last3=Liao|first3=Y.|last4=Plogg|first4=B. A.|last5=Peng|first5=W.|last6=Gundersen|first6=G. A.|last7=Benveniste|first7=H.|last8=Vates|first8=G. E.|last9=Deane|first9=R.|date=2012-08-15|title=A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid|url=https://stm.sciencemag.org/lookup/doi/10.1126/scitranslmed.3003748|journal=Science Translational Medicine|language=en|volume=4|issue=147|pages=147ra111–147ra111|doi=10.1126/scitranslmed.3003748|issn=1946-6234|pmc=PMC3551275|pmid=22896675}}</ref> systems.  
The Perrin technique is based on the hypothesis that the underlying cause of ME/CFS is impaired function of the lymphatic<ref>{{Cite book|title=The Perrin technique : how to beat chronic fatigue syndrome/ME|isbn=978-1-905140-12-1|url=https://www.worldcat.org/oclc/244652322|date=2007|publisher=Hammersmith|last=Perrin, Raymond N.|oclc=244652322|location=London}}</ref> and "glymphatic"<ref>{{Cite journal|last=Iliff|first=J. J.|last2=Wang|first2=M.|last3=Liao|first3=Y.|last4=Plogg|first4=B. A.|last5=Peng|first5=W.|last6=Gundersen|first6=G. A.|last7=Benveniste|first7=H.|last8=Vates|first8=G. E.|last9=Deane|first9=R.|date=2012-08-15|title=A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid|url=https://stm.sciencemag.org/lookup/doi/10.1126/scitranslmed.3003748|journal=Science Translational Medicine|language=en|volume=4|issue=147|pages=147ra111–147ra111|doi=10.1126/scitranslmed.3003748|issn=1946-6234|pmc=PMC3551275|pmid=22896675}}</ref> systems.  
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#tender Perrin’s point (third left intercostal space)<ref>{{Cite journal|last=Puri|first=BK|last2=Gunatilake|first2=KDR|last3=Fernando|first3=KAC|last4=Gurusinghe|first4=AI|last5=Agour|first5=M|last6=Treasaden|first6=IH|date=Feb 2011|title=Increased Tenderness in the Left Third Intercostal Space in Adult Patients with Myalgic Encephalomyelitis: A Controlled Study|url=https://doi.org/10.1177/147323001103900122|journal=Journal of International Medical Research|language=en-US|volume=39|issue=1|pages=212–214|doi=10.1177/147323001103900122|issn=0300-0605|pmc=|pmid=|quote=|last7=|first7=|last8=|first8=|author-link=|author-link2=|access-date=|author-link3=|author-link4=|author-link5=|author-link6=|via=}}</ref>
#tender Perrin’s point (third left intercostal space)<ref>{{Cite journal|last=Puri|first=BK|last2=Gunatilake|first2=KDR|last3=Fernando|first3=KAC|last4=Gurusinghe|first4=AI|last5=Agour|first5=M|last6=Treasaden|first6=IH|date=Feb 2011|title=Increased Tenderness in the Left Third Intercostal Space in Adult Patients with Myalgic Encephalomyelitis: A Controlled Study|url=https://doi.org/10.1177/147323001103900122|journal=Journal of International Medical Research|language=en-US|volume=39|issue=1|pages=212–214|doi=10.1177/147323001103900122|issn=0300-0605|pmc=|pmid=|quote=|last7=|first7=|last8=|first8=|author-link=|author-link2=|access-date=|author-link3=|author-link4=|author-link5=|author-link6=|via=}}</ref>
#tender coeliac plexus, and  
#tender coeliac plexus, and  
#dampened cranial flow<ref name=Hives2017>{{Cite journal|last=Hives|first=Lucy|last2=Bradley|first2=Alice|last3=Richards|first3=Jim|last4=Sutton|first4=Chris|last5=Selfe|first5=James|last6=Basu|first6=Bhaskar|last7=Maguire|first7=Kerry|last8=Sumner|first8=Gail|last9=Gaber|first9=Tarek|date=Nov 2017|title=Can physical assessment techniques aid diagnosis in people with chronic fatigue syndrome/myalgic encephalomyelitis? A diagnostic accuracy study|url=http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-017521|journal=BMJ Open|language=en|volume=7|issue=11|pages=e017521|doi=10.1136/bmjopen-2017-017521|issn=2044-6055|pmc=PMC5695376|pmid=29133321|quote=|author-link=|author-link2=|access-date=|author-link3=|author-link4=|author-link5=|author-link6=|via=}}</ref> Perrin proposes that examination for these five signs is a more accurate means of definitively diagnosing ME/CFS than the commonly used [[Canadian Consensus Criteria]]<ref name=CCC>{{Cite journal|last=Carruthers|first=Bruce M.|last2=Jain|first2=Anil Kumar|last3=De Meirleir|first3=Kenny L.|last4=Peterson|first4=Daniel L.|last5=Klimas|first5=Nancy G.|last6=Lerner|first6=A. Martin|last7=Bested|first7=Alison C.|last8=Flor-Henry|first8=Pierre|last9=Joshi|first9=Pradip|date=Jan 2003|title=Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols|url=http://www.tandfonline.com/doi/full/10.1300/J092v11n01_02|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=11|issue=1|pages=7–115|doi=10.1300/J092v11n01_02|issn=1057-3321|pmc=|pmid=|quote=|author-link=|author-link2=|access-date=|author-link3=|author-link4=|author-link5=|author-link6=|via=}}</ref> or a diagnosis of exclusion.   
#dampened cranial flow<ref name="Hives2017">{{Cite journal|last=Hives|first=Lucy|last2=Bradley|first2=Alice|last3=Richards|first3=Jim|last4=Sutton|first4=Chris|last5=Selfe|first5=James|last6=Basu|first6=Bhaskar|last7=Maguire|first7=Kerry|last8=Sumner|first8=Gail|last9=Gaber|first9=Tarek|date=Nov 2017|title=Can physical assessment techniques aid diagnosis in people with chronic fatigue syndrome/myalgic encephalomyelitis? A diagnostic accuracy study|url=http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-017521|journal=BMJ Open|language=en|volume=7|issue=11|pages=e017521|doi=10.1136/bmjopen-2017-017521|issn=2044-6055|pmc=PMC5695376|pmid=29133321|quote=|author-link=|author-link2=|access-date=|author-link3=|author-link4=|author-link5=|author-link6=|via=}}</ref> Perrin proposes that examination for these five signs is a more accurate means of definitively diagnosing ME/CFS than the commonly used [[Canadian Consensus Criteria]]<ref name="CCC">{{Cite journal|last=Carruthers|first=Bruce M.|last2=Jain|first2=Anil Kumar|last3=De Meirleir|first3=Kenny L.|last4=Peterson|first4=Daniel L.|last5=Klimas|first5=Nancy G.|last6=Lerner|first6=A. Martin|last7=Bested|first7=Alison C.|last8=Flor-Henry|first8=Pierre|last9=Joshi|first9=Pradip|date=Jan 2003|title=Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols|url=http://www.tandfonline.com/doi/full/10.1300/J092v11n01_02|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=11|issue=1|pages=7–115|doi=10.1300/J092v11n01_02|issn=1057-3321|pmc=|pmid=|quote=|author-link=|author-link2=|access-date=|author-link3=|author-link4=|author-link5=|author-link6=|via=}}</ref> or a diagnosis of exclusion.   


The Perrin technique's diagnostic assessment does not involving assessing patient symptoms.<ref name=Perrin2017 />  
The Perrin technique's diagnostic assessment does not involving assessing patient symptoms.<ref name="Perrin2017" />  


==Theory==
==Theory==
The Perrin technique is a bio-mechanical form of therapy for ME/CFS based on the hypothesis that problems with the lymphatic drainage of toxins from the central nervous system are common in patients, with the toxins having resulted from infection, pollution and emotional or physical trauma.<ref name=Perrin2010 /> The Perrin technique hypothesis is that autonomic system over-activity caused an "excess of neurotransmitters such as [[acetylcholine]]", resulting in a build-up of [[choline]] levels in the brain. The supplement [[EPA]] is added to help repair damage caused by the neurotoxins. A part of the brain known as the [[hypothalamus]] is also involved.
The Perrin technique is a bio-mechanical form of therapy for ME/CFS based on the hypothesis that problems with the lymphatic drainage of toxins from the central nervous system are common in patients, with the toxins having resulted from infection, pollution and emotional or physical trauma.<ref name="Perrin2010" /> The Perrin technique hypothesis is that autonomic system over-activity caused an "excess of neurotransmitters such as [[acetylcholine]]", resulting in a build-up of [[choline]] levels in the brain. The supplement [[EPA]] is added to help repair damage caused by the neurotoxins. A part of the brain known as the [[hypothalamus]] is also involved.


The Perrin technique is claimed to produce a lasting improvement in symptoms of ME/CFS.<ref name=Perrin2010 />  
The Perrin technique is claimed to produce a lasting improvement in symptoms of ME/CFS.<ref name="Perrin2010" />  


==Evidence==
==Evidence==
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==Notable studies ==
==Notable studies ==
*2010, Perrin: EPA and the Perrin Technique: a combined approach to treating myalgic encephalomyelitis<ref name=Perrin2010>https://doi.org/10.1186/1744-859X-9-S1-S25</ref> - [https://www.researchgate.net/profile/Raymond-Perrin/publication/49884508_EPA_and_the_Perrin_Technique_a_combined_approach_to_treating_myalgic_encephalomyelitis/links/5585ea5908ae7bc2f44bebf0/EPA-and-the-Perrin-Technique-a-combined-approach-to-treating-myalgic-encephalomyelitis.pdf (Abstract)]
*2010, Perrin: EPA and the Perrin Technique: a combined approach to treating myalgic encephalomyelitis<ref name="Perrin2010">https://doi.org/10.1186/1744-859X-9-S1-S25</ref> - [https://www.researchgate.net/profile/Raymond-Perrin/publication/49884508_EPA_and_the_Perrin_Technique_a_combined_approach_to_treating_myalgic_encephalomyelitis/links/5585ea5908ae7bc2f44bebf0/EPA-and-the-Perrin-Technique-a-combined-approach-to-treating-myalgic-encephalomyelitis.pdf (Abstract)]
*2017, Can physical assessment techniques aid diagnosis in people with chronic fatigue syndrome/myalgic encephalomyelitis? A diagnostic accuracy study<ref name=Hives2017 /> [http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-017521 (Full text)]
*2017, Can physical assessment techniques aid diagnosis in people with chronic fatigue syndrome/myalgic encephalomyelitis? A diagnostic accuracy study<ref name="Hives2017" /> [http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2017-017521 (Full text)]


==Clinicians==
==Clinicians==
*[[Raymond Perrin]]
*[[Raymond Perrin]]
*Collette Bourke


==Risks and safety==
==Risks and safety==

Revision as of 14:58, February 24, 2021

The Perrin technique is a bio-mechanical treatment consisting of lymphatic drainage, spinal and cranial osteopathy developed by UK-based osteopath Raymond Perrin for patients suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).[1]

The Perrin technique is based on the hypothesis that the underlying cause of ME/CFS is impaired function of the lymphatic[2] and "glymphatic"[3] systems.

Diagnostic signs[edit | edit source]

Perrin argues that there are five physical signs are always present in those who suffer from ME/CFS:

  1. mechanical disturbances of the thoracic spine
  2. breast varicosities
  3. tender Perrin’s point (third left intercostal space)[4]
  4. tender coeliac plexus, and
  5. dampened cranial flow[5] Perrin proposes that examination for these five signs is a more accurate means of definitively diagnosing ME/CFS than the commonly used Canadian Consensus Criteria[6] or a diagnosis of exclusion.

The Perrin technique's diagnostic assessment does not involving assessing patient symptoms.[7]

Theory[edit | edit source]

The Perrin technique is a bio-mechanical form of therapy for ME/CFS based on the hypothesis that problems with the lymphatic drainage of toxins from the central nervous system are common in patients, with the toxins having resulted from infection, pollution and emotional or physical trauma.[1] The Perrin technique hypothesis is that autonomic system over-activity caused an "excess of neurotransmitters such as acetylcholine", resulting in a build-up of choline levels in the brain. The supplement EPA is added to help repair damage caused by the neurotoxins. A part of the brain known as the hypothalamus is also involved.

The Perrin technique is claimed to produce a lasting improvement in symptoms of ME/CFS.[1]

Evidence[edit | edit source]

Randomized clinical trials have not been carried out using the Perrin technique. Individual case reports provide some limited evidence of improvement.

Notable studies[edit | edit source]

  • 2010, Perrin: EPA and the Perrin Technique: a combined approach to treating myalgic encephalomyelitis[1] - (Abstract)
  • 2017, Can physical assessment techniques aid diagnosis in people with chronic fatigue syndrome/myalgic encephalomyelitis? A diagnostic accuracy study[5] (Full text)

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Costs and availability[edit | edit source]

Book[edit | edit source]

Perrin technique book.jpg

The Perrin Technique: How to Beat Chronic Fatigue Syndrome/ME is a self-help book by Raymond Perrin.

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 1.3 https://doi.org/10.1186/1744-859X-9-S1-S25
  2. Perrin, Raymond N. (2007). The Perrin technique : how to beat chronic fatigue syndrome/ME. London: Hammersmith. ISBN 978-1-905140-12-1. OCLC 244652322.
  3. Iliff, J. J.; Wang, M.; Liao, Y.; Plogg, B. A.; Peng, W.; Gundersen, G. A.; Benveniste, H.; Vates, G. E.; Deane, R. (August 15, 2012). "A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid". Science Translational Medicine. 4 (147): 147ra111–147ra111. doi:10.1126/scitranslmed.3003748. ISSN 1946-6234. PMC 3551275. PMID 22896675.
  4. Puri, BK; Gunatilake, KDR; Fernando, KAC; Gurusinghe, AI; Agour, M; Treasaden, IH (February 2011). "Increased Tenderness in the Left Third Intercostal Space in Adult Patients with Myalgic Encephalomyelitis: A Controlled Study". Journal of International Medical Research. 39 (1): 212–214. doi:10.1177/147323001103900122. ISSN 0300-0605.
  5. 5.0 5.1 Hives, Lucy; Bradley, Alice; Richards, Jim; Sutton, Chris; Selfe, James; Basu, Bhaskar; Maguire, Kerry; Sumner, Gail; Gaber, Tarek (November 2017). "Can physical assessment techniques aid diagnosis in people with chronic fatigue syndrome/myalgic encephalomyelitis? A diagnostic accuracy study". BMJ Open. 7 (11): e017521. doi:10.1136/bmjopen-2017-017521. ISSN 2044-6055. PMC 5695376. PMID 29133321.
  6. Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip (January 2003). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols". Journal of Chronic Fatigue Syndrome. 11 (1): 7–115. doi:10.1300/J092v11n01_02. ISSN 1057-3321.
  7. Cite error: Invalid <ref> tag; no text was provided for refs named Perrin2017