Tenascin-X

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

The TNXB gene is a protein-encoding gene for the protein tenascin-X. Tenascin-X has an import role im connective tissues (the tissues that support muscles, joints, organs, and skin).[1]

Alternative names[edit | edit source]

The gene TNXB is also known as:

  • Hexabrachion-like protein
  • HXBL
  • Tenascin XB
  • Tenascin XB1
  • Tenascin XB2
  • TENX
  • TENX_HUMAN
  • TNX
  • TNXB1
  • TNXB2
  • TNXBS
  • XB
  • XBS[1]

Function[edit | edit source]

According to research, tenascin-X helps regulate the production and assembly of some types of collagens, and affects the elasticity of the skin.[1][2]

Mutations in TNXB are associated with the connective tissue disease Ehlers-Danlos syndrome (EDS).[1]

ME/CFS[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 1.3 "TNXB gene". MedlinePlus Genetics. Retrieved April 2, 2022.
  2. "TNXB - Gene card". Gene cards. Retrieved March 18, 2022.