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Tarlov cyst
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Perineural cysts or Tarlov cysts (TCs) are nerve root dilations resulting from pathologically increased [[cerebrospinal fluid]] pressure.{{citation needed| date = December 2020}} ==Signs and symptoms== Tarlov cyst often cause widespread [[pain]], and patients often report [[fatigue]]. Some patients with Tarlov cysts may have no symptoms.<ref name=":0">{{Cite web|url=https://rarediseases.org/rare-diseases/tarlov-cysts/ | title = Tarlov Cysts | last = | first = | author-link =| date = |website=National Organization for Rare Disorders|language=en-US|archive-url=|archive-date=|url-status=|access-date=2020-12-17}}</ref> ==Treatment== Treatment is usually only provided if patients are symptomatic, and can involve either surgical or non-surgical approaches.<ref name=":0" /><ref>{{Cite web|url=https://www.aans.org/ | title = Tarlov Cysts: What Are They and How Can They be Treated? | last = American Association of Neurological Surgeons | first = | author-link =| date = |website=AANS|language=en|archive-url=|archive-date=|url-status=|access-date=2020-12-17}}</ref> ==ME/CFS== A study of 197 [[ME/CFS]] and [[Fibromyalgia]] patients found that the prevalence of Tarlov cysts was three times higher in ME/CFS patients than the general population, at 39%.<ref name="Hulens2020">{{Cite journal | last =Hulens | first = Mieke | last2 = Bruyninckx | first2=Frans | last3 = Dankaerts | first3=Wim | last4 = Rasschaert | first4 = Ricky| last5 = De Mulder | first5 = Peter | last6 = Stalmans | first6 = Ingeborg | last7 = Vansant | first7 = Greet | last8 = Bervoets | first8 = Chris| date = 2020-12-01 | title = High Prevalence of Perineural Cysts in Patients with Fibromyalgia and Chronic Fatigue Syndrome|url=https://academic.oup.com/painmedicine/advance-article/doi/10.1093/pm/pnaa410/6015822|journal=Pain Medicine|language=en|pages=pnaa410|doi=10.1093/pm/pnaa410|issn=1526-2375}}</ref> The study's authors conclude:<blockquote>This observation supports the hypothesis that STCs, FM, and CFS may share the same pathophysiological mechanism, i.e., moderately increased cerebrospinal fluid pressure, causing irritation of neurons and axons in dorsal root ganglia</blockquote> ==Notable articles== * 2020, High Prevalence of Perineural Cysts in Patients with Fibromyalgia and Chronic Fatigue Syndrome [https://academic.oup.com/painmedicine/advance-article/doi/10.1093/pm/pnaa410/6015822 (Full text)] == See also == * [[Spine]] * [[Spinal cord]] ==Learn more == * [https://www.aans.org/en/Patients/Neurosurgical-Conditions-and-Treatments/Tarlov-Cyst Tarlov cysts] - American Association of Neurological Surgeons * [https://rarediseases.org/rare-diseases/tarlov-cysts/ Tarlov cysts] - National Organization for Rare Disorders (NORD) == References == {{Reflist}} [[Category:Potential comorbidities]] [[Category:Diagnoses]]
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