Stress: Difference between revisions
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==Notable studies== | ==Notable studies== | ||
Several studies found it is not uncommon to experience major psychological chronic stress (from events such as divorce, bereavement or serious financial worries) in the year prior to developing ME/CFS.<ref>{{Cite journal|last=Hatcher|first=Simon|last2=House|first2=Allan|date=2003-10|title=Life events, difficulties and dilemmas in the onset of chronic fatigue syndrome: a case-control study|url=https://www.ncbi.nlm.nih.gov/pubmed/14580073|journal=Psychological Medicine|volume=33|issue=7|pages=1185–1192|doi=10.1017/s0033291703008274|issn=0033-2917|pmid=14580073}}</ref><ref>{{Cite journal|last=Theorell|first=T.|last2=Blomkvist|first2=V.|last3=Lindh|first3=G.|last4=Evengård|first4=B.|date=1999-5|title=Critical life events, infections, and symptoms during the year preceding chronic fatigue syndrome (CFS): an examination of CFS patients and subjects with a nonspecific life crisis|url=https://www.ncbi.nlm.nih.gov/pubmed/10367610|journal=Psychosomatic Medicine|volume=61|issue=3|pages=304–310|issn=0033-3174|pmid=10367610}}</ref><ref>{{Cite journal|last=Salit|first=Irving E.|date=1997-01-01|title=Precipitating factors for the chronic fatigue syndrome|url=http://www.sciencedirect.com/science/article/pii/S0022395696000507|journal=Journal of Psychiatric Research|volume=31|issue=1|pages=59–65|doi=10.1016/S0022-3956(96)00050-7|issn=0022-3956}}</ref> Chronic psychological stress elevates cortisol which suppresses the Th1 antiviral/intracellular immune response,<ref>{{Cite journal|last=Dhabhar|first=Firdaus S|date=2008-03-15|title=Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection versus Immunopathology|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869337/|journal=Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology|volume=4|issue=1|pages=2–11|doi=10.1186/1710-1492-4-1-2|issn=1710-1484|pmc=2869337|pmid=20525121}}</ref> and the T-cell response.<ref>{{Cite journal|last=Dhabhar|first=Firdaus S|date=2008-03-15|title=Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection versus Immunopathology|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869337/|journal=Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology|volume=4|issue=1|pages=2–11|doi=10.1186/1710-1492-4-1-2|issn=1710-1484|pmc=2869337|pmid=20525121}}</ref> As ME/CFS normally appears after acute viral infection, the presence of chronic stress may alter the immune response to such infections. | |||
==See also == | ==See also == | ||
Revision as of 16:38, August 31, 2019
 | This article is a stub. |
Stress, particularly chronic stress, is considered a potential trigger for ME/CFS. It is also thought to worsen ME/CFS symptoms. ME patients are usually advised to avoid stress wherever possible.
Notable studies[edit | edit source]
Several studies found it is not uncommon to experience major psychological chronic stress (from events such as divorce, bereavement or serious financial worries) in the year prior to developing ME/CFS.[1][2][3] Chronic psychological stress elevates cortisol which suppresses the Th1 antiviral/intracellular immune response,[4] and the T-cell response.[5] As ME/CFS normally appears after acute viral infection, the presence of chronic stress may alter the immune response to such infections.
See also[edit | edit source]
References[edit | edit source]
- ↑ Hatcher, Simon; House, Allan (2003-10). "Life events, difficulties and dilemmas in the onset of chronic fatigue syndrome: a case-control study". Psychological Medicine. 33 (7): 1185–1192. doi:10.1017/s0033291703008274. ISSN 0033-2917. PMID 14580073. Check date values in:
|date=(help) - ↑ Theorell, T.; Blomkvist, V.; Lindh, G.; Evengård, B. (1999-5). "Critical life events, infections, and symptoms during the year preceding chronic fatigue syndrome (CFS): an examination of CFS patients and subjects with a nonspecific life crisis". Psychosomatic Medicine. 61 (3): 304–310. ISSN 0033-3174. PMID 10367610. Check date values in:
|date=(help) - ↑ Salit, Irving E. (January 1, 1997). "Precipitating factors for the chronic fatigue syndrome". Journal of Psychiatric Research. 31 (1): 59–65. doi:10.1016/S0022-3956(96)00050-7. ISSN 0022-3956.
- ↑ Dhabhar, Firdaus S (March 15, 2008). "Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection versus Immunopathology". Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. 4 (1): 2–11. doi:10.1186/1710-1492-4-1-2. ISSN 1710-1484. PMC 2869337. PMID 20525121.
- ↑ Dhabhar, Firdaus S (March 15, 2008). "Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection versus Immunopathology". Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. 4 (1): 2–11. doi:10.1186/1710-1492-4-1-2. ISSN 1710-1484. PMC 2869337. PMID 20525121.
