Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Sickness behavior
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
'''Sickness behavior''', sometimes called '''sickness response'',''''' are nonspecific behavioral changes humans and many animals adopt in response to an infection.{{Citation needed}} Responses include [[lethargy]], lack of appetite, low grade [[fever]], [[sleepiness]] and lack of [[motivation]].{{Citation needed}} It is thought to have evolved to encourage behaviors that conserve energy and allow the host to better mount an immune response against invading [[pathogen]]s.{{Citation needed}} ==Immune response== In response to the presence of a pathogen, proinflammatory [[cytokine]]s [[interleukin 1|IL-1]], [[interleukin 6|IL-6]] and [[TNF-alpha| tumor necrosis factor]] (TNF) are released peripherally.{{Citation needed}} These may then be sensed by the [[vagus nerve]] initiating a set of behavioral responses in the [[brain]].{{Citation needed}} ==See also== *[[Vagus nerve hypothesis]] == Learn more == * [https://academic.oup.com/icb/article/49/3/202/673910 "Vertebrate sickness behaviors: Adaptive and integrated neuroendocrine immune responses"], ''Integrative and Comparative Biology'', Volume 49, Issue 3, September 2009 * [https://royalsocietypublishing.org/doi/full/10.1098/rspb.2014.0218 "When is it socially acceptable to feel sick?"] (review article), ''[[Proceedings of the Royal Society B]]'', August 7, 2014 * [https://openarchive.ki.se/xmlui/handle/10616/44650 "Sickness behavior : immune system influences on brain and behavior"] (series of three papers), [[Karolinska Institutet]], Sweden, May 29, 2015 * [https://www.npr.org/sections/health-shots/2018/01/06/575919771/its-not-just-a-cold-its-sickness-behavior "It's Not Just A Cold, It's 'Sickness Behavior'"], NPR, January 6, 2018 == References == {{Reflist}} [[Category:Immunology]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
Template:Category handler
(
edit
)
Template:Citation needed
(
edit
)
Template:Colon
(
edit
)
Template:Fix
(
edit
)
Template:Fix/category
(
view source
) (protected)
Template:GetFallback
(
edit
)
Template:LangSwitch
(
edit
)
Template:Main other
(
edit
)
Template:Reflist
(
edit
)
Template:Uselang
(
edit
)
Module:Arguments
(
edit
)
Module:Category handler
(
edit
)
Module:Category handler/blacklist
(
edit
)
Module:Category handler/config
(
edit
)
Module:Category handler/data
(
edit
)
Module:Category handler/shared
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Namespace detect/config
(
edit
)
Module:Namespace detect/data
(
edit
)
Module:Unsubst
(
edit
)
Module:Yesno
(
edit
)
This page is a member of 2 hidden categories:
Category:All articles with unsourced statements
Category:Articles with unsourced statements from unknown year
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs