Post-polio syndrome: Difference between revisions
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'''Post-polio syndrome''' ('''PPS''', or '''post-poliomyelitis syndrome''' or '''post-polio sequelae''') is a condition that affects polio survivors years after their recovery from an initial acute attack of the [[poliomyelitis]] virus.<ref name=":0">{{Cite web|url=https://www.ninds.nih.gov/disorders/patient-caregiver-education/fact-sheets/post-polio-syndrome-fact-sheet|title=Post-Polio Syndrome Fact Sheet {{!}} National Institute of Neurological Disorders and Stroke|website=www.ninds.nih.gov|access-date=2020-01-16}}</ref> It is characterized by new and progressive muscular weakness, pain, and fatigue many years after the occurrence of acute paralytic polio.<ref name=":1">{{Cite journal|date=2019-11-14|title=Postpolio Syndrome: Practice Essentials, Pathophysiology, Epidemiology|url=https://emedicine.medscape.com/article/306920-overview#a1}}</ref> | '''Post-polio syndrome''' ('''PPS''', or '''post-poliomyelitis syndrome''' or '''post-polio sequelae''') is a condition that affects polio survivors years after their recovery from an initial acute attack of the [[poliomyelitis]] virus.<ref name=":0">{{Cite web|url=https://www.ninds.nih.gov/disorders/patient-caregiver-education/fact-sheets/post-polio-syndrome-fact-sheet|title=Post-Polio Syndrome Fact Sheet {{!}} National Institute of Neurological Disorders and Stroke|website=www.ninds.nih.gov|access-date=2020-01-16}}</ref> It is characterized by new and progressive muscular weakness, pain, and fatigue many years after the occurrence of acute paralytic polio.<ref name=":1">{{Cite journal|date=2019-11-14|title=Postpolio Syndrome: Practice Essentials, Pathophysiology, Epidemiology|url=https://emedicine.medscape.com/article/306920-overview#a1}}</ref> | ||
== Signs and symptoms == | |||
These include the following:<ref name=":1" /><ref>{{Cite web|url=https://www.ninds.nih.gov/Disorders/All-Disorders/Post-Polio-Syndrome-Information-Page|title=Post-Polio Syndrome Information Page {{!}} National Institute of Neurological Disorders and Stroke|website=www.ninds.nih.gov|access-date=2020-01-16}}</ref> | These include the following:<ref name=":1" /><ref>{{Cite web|url=https://www.ninds.nih.gov/Disorders/All-Disorders/Post-Polio-Syndrome-Information-Page|title=Post-Polio Syndrome Information Page {{!}} National Institute of Neurological Disorders and Stroke|website=www.ninds.nih.gov|access-date=2020-01-16}}</ref> | ||
* Fatigue (both general and muscular) | * Fatigue (both general and muscular) | ||
| Line 14: | Line 14: | ||
* Flat-back syndrome | * Flat-back syndrome | ||
== | == Incidence and prevalence == | ||
The exact incidence and prevalence of postpolio syndrome (PPS) is unknown and statistics vary. Medscape reports the incidence in previous acute polio patients ranges from approximately 22-68%.<ref name=":1" /> The [[National Institutes of Health|NIH]] estimates that the condition affects 25 to 40 percent of polio survivors.<ref name=":0" /> In 1992, a study of former poliomyelitis patients from Allegheny County, Pennsylvania estimates 28.5% of all paralytic polio cases develop PPS.<ref>{{Cite journal|last=Ramlow|first=J.|last2=Alexander|first2=M.|last3=LaPorte|first3=R.|last4=Kaufmann|first4=C.|last5=Kuller|first5=L.|date=1992-10-01|title=Epidemiology of the Post-Polio Syndrome|url=https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/136.7.769|journal=American Journal of Epidemiology|language=en|volume=136|issue=7|pages=769–786|doi=10.1093/aje/136.7.769|issn=0002-9262}}</ref> Suggestions have been made that 100% of polio survivors, if tracked for a long period, can develop some symptoms of PPS.<ref name=":1" /> | The exact incidence and prevalence of postpolio syndrome (PPS) is unknown and statistics vary. Medscape reports the incidence in previous acute polio patients ranges from approximately 22-68%.<ref name=":1" /> The [[National Institutes of Health|NIH]] estimates that the condition affects 25 to 40 percent of polio survivors.<ref name=":0" /> In 1992, a study of former poliomyelitis patients from Allegheny County, Pennsylvania estimates 28.5% of all paralytic polio cases develop PPS.<ref>{{Cite journal|last=Ramlow|first=J.|last2=Alexander|first2=M.|last3=LaPorte|first3=R.|last4=Kaufmann|first4=C.|last5=Kuller|first5=L.|date=1992-10-01|title=Epidemiology of the Post-Polio Syndrome|url=https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/136.7.769|journal=American Journal of Epidemiology|language=en|volume=136|issue=7|pages=769–786|doi=10.1093/aje/136.7.769|issn=0002-9262}}</ref> Suggestions have been made that 100% of polio survivors, if tracked for a long period, can develop some symptoms of PPS.<ref name=":1" /> | ||
Revision as of 21:17, January 16, 2020
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Post-polio syndrome (PPS, or post-poliomyelitis syndrome or post-polio sequelae) is a condition that affects polio survivors years after their recovery from an initial acute attack of the poliomyelitis virus.[1] It is characterized by new and progressive muscular weakness, pain, and fatigue many years after the occurrence of acute paralytic polio.[2]
Signs and symptoms
These include the following:[2][3]
- Fatigue (both general and muscular)
- Muscle weakness
- Muscle pain
- Gait disturbance
- Respiratory problems
- Swallowing problems (dysphagia)
- Autonomic dysfunction
- Sleep apnea
- Flat-back syndrome
Incidence and prevalence
The exact incidence and prevalence of postpolio syndrome (PPS) is unknown and statistics vary. Medscape reports the incidence in previous acute polio patients ranges from approximately 22-68%.[2] The NIH estimates that the condition affects 25 to 40 percent of polio survivors.[1] In 1992, a study of former poliomyelitis patients from Allegheny County, Pennsylvania estimates 28.5% of all paralytic polio cases develop PPS.[4] Suggestions have been made that 100% of polio survivors, if tracked for a long period, can develop some symptoms of PPS.[2]
Research studies
- 2019, Differentiating post-polio syndrome from myalgic encephalomyelitis and chronic fatigue syndrome[5] - (Abstract)
See also
Learn more
References
- ↑ 1.0 1.1 "Post-Polio Syndrome Fact Sheet | National Institute of Neurological Disorders and Stroke". www.ninds.nih.gov. Retrieved January 16, 2020.
- ↑ 2.0 2.1 2.2 2.3 "Postpolio Syndrome: Practice Essentials, Pathophysiology, Epidemiology". November 14, 2019. Cite journal requires
|journal=(help) - ↑ "Post-Polio Syndrome Information Page | National Institute of Neurological Disorders and Stroke". www.ninds.nih.gov. Retrieved January 16, 2020.
- ↑ Ramlow, J.; Alexander, M.; LaPorte, R.; Kaufmann, C.; Kuller, L. (October 1, 1992). "Epidemiology of the Post-Polio Syndrome". American Journal of Epidemiology. 136 (7): 769–786. doi:10.1093/aje/136.7.769. ISSN 0002-9262.
- ↑ Klebek, Lauren; Sunnquist, Madison; Jason, Leonard A. (October 2, 2019). "Differentiating post-polio syndrome from myalgic encephalomyelitis and chronic fatigue syndrome". Fatigue: Biomedicine, Health & Behavior. 7 (4): 196–206. doi:10.1080/21641846.2019.1687117. ISSN 2164-1846.
