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===CFS following Epstein Barr Virus (EBV) Infection === In a large longitudinal study, White and colleagues followed up on 108 persons with Epstein Barr Virus (EBV-) infection, 83 patients with glandular not caused by EBV and 54 subjects with an ordinary upper respiratory tract infection (URTI).<ref name="WhiteThomas1998">{{Cite journal | last = White | first = P. D. | last2 = Thomas | first2 = J.M. | last3 = Amess | first3 = J. | last4 = Crawford | first4 = D.H. | last5 = Grover | first5 = S.A. | last6 = Kangro | first6 = H.O. | last7 = Clare | first7 = A.W. | date = Dec 1998| title = Incidence, risk and prognosis of acute and chronic fatigue syndromes and psychiatric disorders after glandular fever |url =https://www.ncbi.nlm.nih.gov/pubmed/9926075|journal=The British Journal of Psychiatry: The Journal of Mental Science|volume=173 | pages = 475–481|doi=10.1192/bjp.173.6.475|issn=0007-1250|pmid=9926075}}</ref> These patients were followed up for more than six months to assess symptoms and disability. The results suggested that a distinct fatigue syndrome existed after glandular fever whose constituent symptoms were reliable over time.<ref name="WhiteThomas1995">{{Cite journal | last = White | first = P. D. | last2 = Thomas | first2 = J.M. | last3 = Amess | first3 = J. | last4 = Grover | first4 = S.A. | last5 = Kangro | first5 = H.O. | last6 = Clare | first6 = A.W. | date = Sep 1995| title = The existence of a fatigue syndrome after glandular fever |url =https://www.ncbi.nlm.nih.gov/pubmed/8588009|journal=Psychological Medicine|volume=25|issue=5 | pages = 907–916|issn=0033-2917|pmid=8588009}}</ref> The prevalence of CFS according to the Fukuda definition was 10%, six months after EBV-infection compared to 0% following an ordinary URTI.<ref name="WhiteThomas1998" /> No psychiatric disorder was significantly more prevalent six months following EBV-infection than before.<ref name="WhiteThomas1998" /> According to White et al. “The validity of the fatigue syndrome was supported, separate from psychiatric disorders in general and depressive disorders in particular.”<ref name="ClareAmess1995">{{Cite journal | last = Clare | first = A. W. | last2 = Amess | first2 = J. | last3 = Thomas | first3 = J.M. | last4 = Kangro | first4 = H.O. | last5 = Grover | first5 = S.A. | last6 = White | first6 = P. D. | date = Sep 1995| title = The validity and reliability of the fatigue syndrome that follows glandular fever |url =https://www.cambridge.org/core/journals/psychological-medicine/article/validity-and-reliability-of-the-fatigue-syndrome-that-follows-glandular-fever/E86878CFD22D70A59CF4E6AA1802885E|journal=Psychological Medicine|language=en|volume=25|issue=5 | pages = 917–924|doi=10.1017/S0033291700037405|issn=1469-8978}}</ref> Using data from the General Practice Research Database (GPRD), White and colleagues reported that significantly more fatigue symptoms were reported in the months following EBV-infection compared to tonsillitis and influenza.<ref>{{Cite journal | last = Petersen | first = I. | last2 = Thomas | first2 = J.M. | last3 = Hamilton | first3 = W.T. | last4 = White | first4 = P. D. | date = Jan 2006| title = Risk and predictors of fatigue after infectious mononucleosis in a large primary-care cohort|url=https://www.ncbi.nlm.nih.gov/pubmed/16330509|journal=QJM: monthly journal of the Association of Physicians|volume=99|issue=1 | pages = 49–55|doi=10.1093/qjmed/hci149|issn=1460-2725|pmid=16330509}}</ref> White is also a member of The International Collaborative on Fatigue Following Infection (COFFI)<ref>{{Cite journal | last = Katz | first = Ben Z | author-link = Ben Katz | last2 = Collin | first2 = Simon M | authorlink2 = Simon Collin | last3 = Murphy | first3 = Gabrielle | author-link3 = Gabrielle Murphy | last4 = Moss-Morris | first4 = Rona | author-link4 = Rona Moss-Morris | last5 = Wyller | first5 = Vegard Bruun | author-link5 = Vegard Bruun Wyller | last6 = Wensaas | first6 = Knut-Arne | last7 = Hautvast | first7 = Jeannine L.A. | last8 = Bleeker-Rovers | first8 = Chantal P | last9 = Vollmer-Conna | first9 = Ute | authorlink9 = Uté Vollmer-Conna | date = 2018 | title=The International Collaborative on Fatigue Following Infection (COFFI)|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333416/|journal=Fatigue: biomedicine, health & behavior|volume=6|issue=2|pages=106–121|doi=10.1080/21641846.2018.1426086|issn=2164-1846|pmc=6333416|pmid=30666281|quote=}}</ref> which has been established to study post-infection fatigue and related symptoms by sharing data and samples from cohorts around the world.<ref>{{Cite web|url=https://internationalcoffi.wordpress.com/| title = COFFI|website=COFFI|language=en|access-date=2019-08-19}}</ref>
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