Outcome switching
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Outcome switching or outcome swapping is when authors of a clinical trial "move the goal posts" during a trial, which may be done to achieve the desired results.
The PACE trial authors, in a clinical trial of ME/CFS patients undergoing GET/CBT, employed this tactic.
Articles on Outcome switching in clinical trials[edit | edit source]
- How Outcome Switching is Corrupting Medical Research[1]
- For my next trick... [2]
- Is Outcome Switching Still A Problem In Clinical Trials?[3]
- How researchers dupe the public with a sneaky practice called "outcome switching"[4]
Tracking outcome switching
PACE trial[edit | edit source]
- In 2016, Julie Rehmeyer gave the talk Bad Statistics, Bad Reporting, Bad Impact on Patients: The Story of the PACE Trial Slideshow given at the 2016 Joint Statistics Meetings[6] (Notes may be be viewed by clicking the “Notes” icon just above the comments section in the slideshow link.)
- David Tuller spoke about and answered questions on the PACE trial and its flaws.
- Feb 28, 2016, David Tuller gave a speech with Q&As.[7]
- Feb 27, 2016, An Interview with David Tuller, held at The Forgotten Plague Conference, discussing the flaws of the Pace trial.[8]
Learn more[edit | edit source]
See also[edit | edit source]
- Alem Matthees won a Freedom of Information Act tribunal for the release of the PACE trial data.
References[edit | edit source]
- ↑ Lane, Christopher (April 30, 2016). "How Outcome Switching is Corrupting Medical Research". Psychology Today. Retrieved August 11, 2018. Cite has empty unknown parameter:
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(help) - ↑ "For my next trick..." The Economist. March 26, 2016. Retrieved August 11, 2018. Cite has empty unknown parameter:
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(help) - ↑ Miseta, Ed (March 7, 2016). "Is Outcome Switching Still A Problem In Clinical Trials". www.clinicalleader.com. Retrieved August 11, 2018. Cite has empty unknown parameter:
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(help) - ↑ Belluz, Julia (December 29, 2015). "How researchers dupe the public with a sneaky practice called "outcome switching"". Vox. Retrieved August 11, 2018. Cite has empty unknown parameter:
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(help) - ↑ "Tracking switched outcomes in clinical trials". COMPare. Retrieved August 11, 2018.
- ↑ Rehmeyer, Julie (August 1, 2016). "Bad Statistics, Bad Reporting, Bad Impact on Patients: The Story of the PACE trial". www.slideshare.net. Retrieved August 11, 2018 – via SlideShare. Cite has empty unknown parameter:
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(help) - ↑ Tuller, David (March 28, 2016). "Lezing dr David Tuller met Nederlandse ondertiteling". YouTube. ME/cvs Vereniging. Cite has empty unknown parameter:
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(help) - ↑ Tuller, David (March 4, 2016). "Interview with David Tuller (Amsterdam, 27th February 2016)". YouTube. Frank Twisk. Cite has empty unknown parameter:
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(help) - ↑ "PACE trial - MEpedia". me-pedia.org. Retrieved August 11, 2018.