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Nicotinamide adenine dinucleotide
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{{stub}} '''Nicotinamide adenine dinucleotide''' or '''NAD''' or '''NADH''' is a coenzyme found in all living cells. Nicotinamide adenine dinucleotide exists in two forms, an oxidized and reduced form abbreviated as NAD+ and NADH respectively. ==Evidence == A systematic review of alternative treatments found evidence of the effectiveness of oral NADH in patients with [[ME/CFS]].<ref name="Porter2010" /> ==Notable studies== *2016, [https://www.ncbi.nlm.nih.gov/pubmed/25788480 Pharmacological NAD-Boosting Strategies Improve Mitochondrial Homeostasis in Human Complex I-Mutant Fibroblasts] *2010, [https://www.researchgate.net/profile/Leonard_Jason/publication/41655043_Alternative_Medical_Interventions_Used_in_the_Treatment_and_Management_of_Myalgic_EncephalomyelitisChronic_Fatigue_Syndrome_and_Fibromyalgia/links/5581c5b408ae6cf036c16e0b/Alternative-Medical-Interventions-Used-in-the-Treatment-and-Management-of-Myalgic-Encephalomyelitis-Chronic-Fatigue-Syndrome-and-Fibromyalgia.pdf Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia]<ref name="Porter2010">{{Cite journal | last = Porter | first = Nicole S. | authorlink = Nicole Porter | last2 = Jason | first2 = Leonard A. | authorlink2=Leonard Jason | last3 = Boulton | first3 = Aaron | authorlink3 = | last4 = Bothne | first4 = Nancy | authorlink4 = | last5 = Coleman | first5 = Blair | authorlink5 = | date = Mar 2010 | title = Alternative medical interventions used in the treatment and management of myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia|url=https://www.researchgate.net/profile/Leonard_Jason/publication/41655043_Alternative_Medical_Interventions_Used_in_the_Treatment_and_Management_of_Myalgic_EncephalomyelitisChronic_Fatigue_Syndrome_and_Fibromyalgia/links/5581c5b408ae6cf036c16e0b/Alternative-Medical-Interventions-Used-in-the-Treatment-and-Management-of-Myalgic-Encephalomyelitis-Chronic-Fatigue-Syndrome-and-Fibromyalgia.pdf|journal=Journal of Alternative and Complementary Medicine (New York, N.Y.)|volume=16|issue=3|pages=235β249|doi=10.1089/acm.2008.0376|issn=1557-7708|pmc=|pmid=20192908|access-date=|quote=|via=}}</ref> * 2004, Comparison of oral nicotinamide adenine dinucleotide (NADH) versus conventional therapy for chronic fatigue syndrome<ref name="Santaella2004">{{Cite web|url=https://pubmed.ncbi.nlm.nih.gov/15377055/ | title = Comparison of oral nicotinamide adenine dinucleotide (NADH) versus conventional therapy for chronic fatigue syndrome | last = Santaella | first = ML | authorlink = | last2 = Font | first2 = I | authorlink2 = | date = Jun 2004 | website = | pages = 89-93|language=en|pmid=15377055|archive-url=|archive-date=|url-status=|access-date= | last3 = Disdier | first3 = OM|journal=Puerto Rico health sciences journal|volume=23|issue=2}}</ref> - [http://prhsj.rcm.upr.edu/index.php/prhsj/article/download/426/312 (Full text)] *1999, Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome<ref name="Forsyth1999">{{Cite journal | last = Forsyth | first = Linda M | last2 = Preuss | first2 = Harry G | last3 = MacDowell | first3 = Ana L | last4 = Chiazze | first4 = Leonard | last5 = Birkmayer | first5 = George D | last6 = Bellanti | first6 = Joseph A | date = 1999-02-01 | title = Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome|url=http://www.sciencedirect.com/science/article/pii/S1081120610625951|journal=Annals of Allergy, Asthma & Immunology|language=en|volume=82|issue=2|pages=185β191|doi=10.1016/S1081-1206(10)62595-1|issn=1081-1206}}</ref> - [http://www.enadastudies.com/wp-content/uploads/2015/08/Therapeutic-effects-of-oral-NADH-on-the-symptoms-of-patients-with-chronic-fatigue-syndrome.pdf (Full text)] ==Blogs and articles == *2015, [http://blogs.scientificamerican.com/guest-blog/beyond-resveratrol-the-anti-aging-nad-fad/ Beyond Resveratrol: The Anti-Aging NAD Fad] ==Learn more == ==See also== *[[Mitochondrion]] *[[Sirtuin 1]] (SIRT1) ==References == {{Reflist}} [[Category:Potential treatments]] [[Category:Supplements]] [[Category:Biochemistry and cell biology]] [[Category:Coenzymes]]
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