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==Notable studies== *1996, Preliminary determination of the association between symptom expression and urinary metabolites in subjects with [[chronic fatigue syndrome]]<ref>{{Cite journal | last = McGregor | first = N.R. | authorlink = Neil McGregor | last2 = Dunstan | first2 = R. H. | authorlink2 = | last3 = Zerbes | first3 = M. | authorlink3 = | last4 = Butt | first4 = H.L. | author-link4 = Henry Butt | last5 = Roberts | first5 = T.K. | authorlink5 = | last6 = Klineberg | first6 = I.J. | date = Jun 1996 | title = Preliminary determination of the association between symptom expression and urinary metabolites in subjects with chronic fatigue syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/8809350|journal=Biochemical and Molecular Medicine|volume=58|issue=1 | pages = 85β92|issn=1077-3150|pmid=8809350|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/8809350 (Abstract)] *1997, A Preliminary Assessment of the Association of SCL-90-R Psychological Inventory Responses with Changes in Urinary Metabolites in Patients with [[Chronic Fatigue Syndrome]]<ref>{{Cite journal | last = McGregor | first = N.R. | authorlink = Neil McGregor | last2 = Dunstan | first2 = R. H. | authorlink2 = | last3 = Butt | first3 = H.L. | author-link3 = Henry Butt | last4 = Roberts | first4 = T.K. | authorlink4 = | last5 = Klineberg | first5 = I.J. | authorlink5 = | last6 = Zerbes | first6 = M. | date = Jan 1997 | title = A Preliminary Assessment of the Association of SCL-90-R Psychological Inventory Responses with Changes in Urinary Metabolites in Patients with Chronic Fatigue Syndrome|url=http://www.tandfonline.com/doi/full/10.1300/J092v03n01_03|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=3|issue=1|pages=17β37|doi=10.1300/J092v03n01_03|issn=1057-3321|quote=|via=}}</ref> - [http://dx.doi.org/10.1300/J092v03n01_03 (Abstract)] *1998, Immunological and Haematological Parameters in Patients with Chronic Fatigue Syndrome<ref>{{Cite journal | last = Roberts | first = Timothy K. | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Dunstan | first3 = R. Hugh | last4 = Donohoe | first4 = Mark | last5 = Murdoch | first5 = Raymond N. | last6 = Zhang | first6 = S. | last7 = Hope | first7 = D. | last8 = Butt | first8 = Henry L. | authorlink8 = Henry Butt | last9 = Watkins | first9 = Jennifer A. | last10 = Taylor | first10 = Warren G. | date = 1998 | title = Immunological and Haematological Parameters in Patients with Chronic Fatigue Syndrome|url=http://dx.doi.org/10.1300/J092v04n04_05|journal=Journal of Chronic Fatigue Syndrome|volume=4|issue=4 | pages = 51-65 |doi=10.1300/J092v04n04_05|via=|quote= }}</ref> - [http://dx.doi.org/10.1300/J092v04n04_05 (Abstract)] *2000, Investigation of Erythrocyte Oxidative Damage in Rheumatoid Arthritis and [[Chronic Fatigue Syndrome]]<ref>{{Cite journal | last = Richards | first = R.S. | authorlink = | last2 = Roberts | first2 = T.K. | authorlink2 = | last3 = Mathers | first3 = D. | authorlink3 = | last4 = Dunstan | first4 = R.H. | authorlink4 = | last5 = McGregor | first5 = N.R. | authorlink5 = Neil McGregor | last6 = Butt | first6 = H.L. | author-link6 = Henry Butt | date = Jan 2000 | title = Investigation of Erythrocyte Oxidative Damage in Rheumatoid Arthritis and Chronic Fatigue Syndrome|url=http://www.tandfonline.com/doi/full/10.1300/J092v06n01_04|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=6|issue=1|pages=37β46|doi=10.1300/J092v06n01_04|issn=1057-3321|quote=|via=}}</ref> - [http://dx.doi.org/10.1300/J092v06n01_04 (Abstract)] *2000, The Biochemistry of Chronic Pain and Fatigue<ref>{{Cite journal | last = McGregor | first = Neil R. | authorlink = Neil McGregor | last2 = Niblett | first2 = Suzanne | authorlink2 = | last3 = Bligh | first3 = Phillip Clifton | authorlink3 = | last4 = Dunstan | first4 = R. Hugh | authorlink4 = | last5 = Fulcher | first5 = Greg | authorlink5 = | last6 = Hoskin | first6 = Leigh | last7 = Butt | first7 = Henry L. | authorlink7 = Henry Butt | last8 = Roberts | first8 = Timothy K. | last9 = King | first9 = Katrina | date = Jan 2000 | title = The Biochemistry of Chronic Pain and Fatigue|url=http://www.tandfonline.com/doi/full/10.1300/J092v07n01_02|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=7|issue=1|pages=3β21|doi=10.1300/J092v07n01_02|issn=1057-3321|quote=|via=}}</ref> - [https://www.tandfonline.com/doi/abs/10.1300/J092v07n01_02 (Abstract)] *2000, Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome<ref>{{Cite journal | last = Richards | first = R.S. | authorlink = | last2 = Roberts | first2 = T.K. | authorlink2 = | last3 = McGregor | first3 = N.R. | authorlink3 = Neil McGregor | last4 = Dunstan | first4 = R.H. | authorlink4 = | last5 = Butt | first5 = H.L. | authorlink5 = Henry Butt | date = Feb 2000 | title = Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome|url=http://www.tandfonline.com/doi/full/10.1179/rer.2000.5.1.35|journal=Redox Report|language=en|volume=5|issue=1|pages=35β41|doi=10.1179/rer.2000.5.1.35|issn=1351-0002|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/10905542 (Abstract)] *2000, Erythrocyte Morphology in Rheumatoid Arthritis and [[Chronic Fatigue Syndrome]]: A Preliminary Study<ref>{{Cite journal | last = Richards | first = R.S. | authorlink = | last2 = Roberts | first2 = T.K. | authorlink2 = | last3 = Mathers | first3 = D. | authorlink3 = | last4 = Dunstan | first4 = R.H. | authorlink4 = | last5 = McGregor | first5 = N.R. | authorlink5 = Neil McGregor | last6 = Butt | first6 = H.L. | author-link6 = Henry Butt | date = Jan 2000 | title = Erythrocyte Morphology in Rheumatoid Arthritis and Chronic Fatigue Syndrome: A Preliminary Study|url=http://www.tandfonline.com/doi/full/10.1300/J092v06n01_03|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=6|issue=1|pages=23β35|doi=10.1300/J092v06n01_03|issn=1057-3321|quote=|via=}}</ref> - [http://dx.doi.org/10.1300/J092v06n01_03 (Abstract)] *2001, A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome<ref>{{Cite journal | last = De Becker | first = P. | authorlink = Pascale De Becker | last2 = McGregor | first2 = N. | authorlink2 = Neil McGregor | last3 = De Meirleir | first3 = K. | authorlink3 = Kenny De Meirleir | author-link4 = | authorlink5 = | date = Sep 2001 | title = A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/11555128|journal=Journal of Internal Medicine|volume=250|issue=3|pages=234β240|issn=0954-6820|pmid=11555128|quote=|via=}}</ref> - [https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2796.2001.00890.x (Full text)] *2002, Activity Limitations and Participation Restrictions in Patients with [[Chronic Fatigue Syndrome]]βConstruction of a Disease Specific Questionnaire<ref name="Activity Limitations, 2002" /> - [http://dx.doi.org/10.1300/J092v10n03_02 (Abstract)] *2002, Possible Triggers and Mode of Onset of [[Chronic Fatigue Syndrome]]<ref>{{Cite journal | last = De Becker | first = P. | authorlink = Pascale De Becker | last2 = McGregor | first2 = N. | authorlink2 = Neil McGregor | last3 = De Meirleir | first3 = K. | authorlink3 = Kenny De Meirleir | author-link4 = | authorlink5 = | date = Jan 2002 | title = Possible Triggers and Mode of Onset of Chronic Fatigue Syndrome|url=http://www.tandfonline.com/doi/full/10.1300/J092v10n02_02|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=10|issue=2|pages=3β18|doi=10.1300/J092v10n02_02|issn=1057-3321|quote=|via=}}</ref> - [http://dx.doi.org/10.1300/J092v10n02_02 (Abstract)] *2003, Monitoring a Hypothetical Channelopathy in [[Chronic Fatigue Syndrome]]: Preliminary Observations<ref name="Hypothetical Channelopathy, 2003" /> - [http://dx.doi.org/10.1300/J092v11n01_03 (Abstract)] *2003, Associations between bronchial hyperresponsiveness and immune cell parameters in patients with [[chronic fatigue syndrome]]<ref name="bronchial hyperresponsiveness, 2003" /> - [https://www.ncbi.nlm.nih.gov/pubmed/12684286 (Abstract)] *2003, Comparison of Activity Limitations/Participation Restrictions Among [[Fibromyalgia]] and [[Chronic Fatigue Syndrome]] Patients<ref name="Nijs, 2003" /> - [http://dx.doi.org/10.1300/J092v11n04_02 (Abstract)] *2004, Membrane Damaging Toxins from Coagulase-Negative Staphylococcus Are Associated with Self-Reported Temporomandibular Disorder (TMD) in Patients with [[Chronic Fatigue Syndrome]]<ref>{{Cite journal | last = Metcalf | first = Lee N. | authorlink = | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Roberts | first3 = Timothy K. | date = Jan 2004 | title = Membrane Damaging Toxins from Coagulase-Negative Staphylococcus Are Associated with Self-Reported Temporomandibular Disorder (TMD) in Patients with Chronic Fatigue Syndrome|url=http://www.tandfonline.com/doi/full/10.1300/J092v12n03_03|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=12|issue=3|pages=25β43|doi=10.1300/J092v12n03_03|issn=1057-3321|quote=|via=}}</ref> - [http://dx.doi.org/10.1300/J092v12n03_03 (Abstract)] *2004, Association Between Oxidative Damage Markers and Self-Reported Temporomandibular Dysfunction Symptoms in Patients with [[Chronic Fatigue Syndrome]]<ref>{{Cite journal | last = Richards | first = Ross S. | authorlink = | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Roberts | first3 = Timothy K. | date = Jan 2004 | title = Association Between Oxidative Damage Markers and Self-Reported Temporomandibular Dysfunction Symptoms in Patients with Chronic Fatigue Syndrome|url=http://www.tandfonline.com/doi/full/10.1300/J092v12n03_04|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=12|issue=3 | pages = 45β61|doi=10.1300/J092v12n03_04|issn=1057-3321|quote=|via=}}</ref> - [http://dx.doi.org/10.1300/J092v12n03_04 (Abstract)] *2004, Clinical and Biochemical Characteristics Differentiating Chronic Fatigue Syndrome from Major Depression and Healthy Control Populations: Relation to Dysfunction in the RNase L Pathway<ref>{{Cite journal | last = Suhadolnik | first = Robert J. | authorlink = | last2 = Peterson | first2 = Daniel L. | authorlink2 = Daniel Peterson | last3 = Reichenbach | first3 = Nancy L. | authorlink3 = | last4 = Roen | first4 = Gail | authorlink4 = | last5 = Metzger | first5 = Melodie | authorlink5 = | last6 = McCahan | first6 = John | last7 = O'brien | first7 = Karen | last8 = Welsch | first8 = Suzanne | last9 = Gabriel | first9 = Jerome | last10 = Gaughan | first10 = John P. | last11 = McGregor | first11 = Neil R. | authorlink11 = Neil McGregor | date = 2004 | title = Clinical and Biochemical Characteristics Differentiating Chronic Fatigue Syndrome from Major Depression and Healthy Control Populations: Relation to Dysfunction in the RNase L Pathway|url=https://www.tandfonline.com/doi/abs/10.1300/J092v12n01_02|journal=Journal of Chronic Fatigue Syndrome|volume=12|issue=1 | pages = 5-35|doi=10.1300/J092v12n01_02|quote=|via=}}</ref> - [https://www.researchgate.net/publication/249886680_Clinical_and_Biochemical_Characteristics_Differentiating_Chronic_Fatigue_Syndrome_from_Major_Depression_and_Healthy_Control_Populations (Full Text)] *2007, Hematologic and urinary excretion anomalies in patients with [[chronic fatigue syndrome]]<ref>{{Cite journal | last = Niblett | first = Suzanne H. | last2 = King | first2 = Katrina E. | last3 = Dunstan | first3 = R. Hugh | last4 = Clifton-Bligh | first4 = Phillip | last5 = Hoskin | first5 = Leigh A. | last6 = Roberts | first6 = Timothy K. | last7 = Fulcher | first7 = Greg R. | last8 = McGregor | first8 = Neil R. | authorlink8 = Neil McGregor | last9 = Dunsmore | first9 = Julie C. | last10 = Butt | first10 = Henry | authorlink10 = Henry Butt | last11 = Klineberg | first11 = Iven | last12 = Rothkirch | first12 = T.B. | date = Sep 2007 | title = Hematologic and Urinary Excretion Anomalies in Patients with Chronic Fatigue Syndrome|url=http://journals.sagepub.com/doi/10.3181/0702-RM-44|journal=Experimental Biology and Medicine|language=en|volume=232|issue=8|pages=1041β1049|doi=10.3181/0702-rm-44|issn=1535-3702|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/17720950 (Abstract)] *2009, Increased [[d-lactic acid]] intestinal bacteria in patients with [[chronic fatigue syndrome]]<ref>{{Cite journal | last = Sheedy | first = John R. | authorlink = | last2 = Wettenhall | first2 = Richard E. H. | authorlink2 = | last3 = Scanlon | first3 = Denis | authorlink3 = | last4 = Gooley | first4 = Paul R. | authorlink4 = Paul Gooley | last5 = Lewis | first5 = Donald P. | authorlink5 = Donald Lewis | last6 = McGregor | first6 = Neil | authorlink6 = Neil McGregor | last7 = Stapleton | first7 = David I. | last8 = Butt | first8 = Henry L. | authorlink8 = Henry Butt | last9 = De Meirleir | first9 = Kenny L. | authorlink9 = Kenny De Meirleir | date = Jul 2009 | title = Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/19567398|journal=In Vivo (Athens, Greece)|volume=23|issue=4 | pages = 621β628|issn=0258-851X|pmid=19567398|quote=|via=}}</ref> - [http://iv.iiarjournals.org/content/23/4/621.long (Full text)] *2012, NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome<ref>{{Cite journal | last = Armstrong | first = Christopher W. | authorlink = Christopher Armstrong | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Sheedy | first3 = John R. | authorlink3 = | last4 = Buttfield | first4 = Ian | author-link4 = | last5 = Butt | first5 = Henry L. | authorlink5 = Henry Butt | last6 = Gooley | first6 = Paul R. | authorlink6 = Paul Gooley | date = Oct 2012 | title = NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome|url=https://linkinghub.elsevier.com/retrieve/pii/S0009898112003270|journal=Clinica Chimica Acta|language=en|volume=413|issue=19-20|pages=1525β1531|doi=10.1016/j.cca.2012.06.022|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/22728138 (Abstract)] *2014, Metabolism in chronic fatigue syndrome<ref>{{Cite journal | last = Armstrong | first = Christopher W. | authorlink = Christopher Armstrong | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Butt | first3 = Henry L. | authorlink3 = Henry Butt | last4 = Gooley | first4 = Paul R. | authorlink4 = Paul Gooley | date = 2014 | title = Metabolism in chronic fatigue syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/25344988|journal=Advances in Clinical Chemistry|volume=66|pages=121β172|issn=0065-2423|pmid=25344988|via=}}</ref> - [[pubmed:25344988|(Abstract)]] *2015, Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in [[chronic fatigue syndrome]] patients<ref>{{Cite journal | last = Armstrong | first = Christopher W. | authorlink = Christopher Armstrong | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Butt | first4 = Henry L. | authorlink4 = Henry Butt | last5 = Gooley | first5 = Paul R. | authorlink5 = Paul Gooley | date = Dec 2015 | title = Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients|url=http://link.springer.com/10.1007/s11306-015-0816-5|journal=Metabolomics|language=en|volume=11|issue=6|pages=1626β1639|doi=10.1007/s11306-015-0816-5|issn=1573-3882|quote=|via=}}</ref> - [http://link.springer.com/article/10.1007%2Fs11306-015-0816-5 (Abstract)] *2016, Widespread pain and altered renal function in [[ME/CFS]] patients<ref>{{Cite journal | last = McGregor | first = Neil R. | authorlink = Neil McGregor | last2 = Armstrong | first2 = Christopher W. | authorlink2 = Christopher Armstrong | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Butt | first4 = Henry L. | authorlink4 = Henry Butt | last5 = Gooley | first5 = Paul R. | authorlink5 = Paul Gooley | date = 2016-07-02 | title = Widespread pain and altered renal function in ME/CFS patients|url=http://www.tandfonline.com/doi/full/10.1080/21641846.2016.1207400|journal = Fatigue: Biomedicine, Health & Behavior |language=en|volume=4|issue=3|pages=132β145|doi=10.1080/21641846.2016.1207400|issn=2164-1846|pmc=|pmid=|access-date=|quote=|via=}}</ref> - [http://www.tandfonline.com/doi/abs/10.1080/21641846.2016.1207400?journalCode=rftg20 (Abstract)] *2017, The association of fecal microbiota and fecal, blood serum and urine metabolites in [[ME/CFS|myalgic encephalomyelitis/chronic fatigue syndrome]]<ref>{{Cite journal | last = Armstrong | first = Christopher W. | authorlink = Christopher Armstrong | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Butt | first4 = Henry L. | authorlink4 = Henry Butt | last5 = Gooley | first5 = Paul R. | authorlink5 = Paul Gooley | date = Jan 2017 | title = The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome|url=http://link.springer.com/10.1007/s11306-016-1145-z|journal=Metabolomics|language=en|volume=13|issue=1|pages=|doi=10.1007/s11306-016-1145-z|issn=1573-3882|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/22728138 (Abstract)] *2019, [[Post-exertional malaise|Post-Exertional Malaise]] Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases<ref>{{Cite journal | last = McGregor | first = Neil R. | authorlink = Neil McGregor | last2 = Armstrong | first2 = Christopher W. | authorlink2 = Christopher Armstrong | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Gooley | first4 = Paul R. | authorlink4 = Paul Gooley | date = 2019-07-04 | title = Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases|url=https://www.mdpi.com/2075-4418/9/3/70|journal=Diagnostics|language=en|volume=9|issue=3 | pages = 70|doi=10.3390/diagnostics9030070|issn=2075-4418|quote=|via=}}</ref> - [https://www.mdpi.com/2075-4418/9/3/70/htm (Full text)]
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