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Natural killer cell
(section)
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===Multiple sclerosis=== In 2009 a team led by Dr Hugh Brady from the Department of Life Sciences at Imperial College London, identified a master gene [[E4bp4]] which causes blood [[stem cells]] to turn into disease-fighting 'Natural Killer' [[autoimmune cells]]. Using a mouse model scientists successfully 'knocked out' the gene known as E4bp4, creating the world's first animal model entirely lacking 'Natural Killer' cells, leaving all other blood cells and immune cells intact. This breakthrough model should help solve the mystery of the role that Natural Killer cells play in autoimmune diseases, such as [[diabetes]] and [[multiple sclerosis]]. This could now lead to new ways of treating these conditions with a drugs which will react with the protein expressed by their E4bp4 gene.<ref name="E4bp4Press">{{Cite web | title = Master gene that switches on disease-fighting cells identified by scientists - Press release | date = September 15, 2009 | website = Imperial College London | url =https://www.imperial.ac.uk/news/73201/master-gene-that-switches-disease-fighting-cells/|access-date=Sep 14, 2022}}</ref><ref name="GascoyneD2009" />
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