Muscle spasm
Muscle spasms or cramp, also known as involuntary hypertonicity, are unintentional and painful muscle contractions.[1] The pain from spasms is very sharp and intense, for example waking someone suddenly in the night, and the muscle may sometimes look hard under the skin.[2] Spasms can make it impossible to use the muscle temporarily.[2]
Prevalence[edit | edit source]
Symptom recognition[edit | edit source]
Muscle spasms are not considered a diagnostic criteria for ME/CFS, but have been found to occur in people with ME/CFS.[3][4][5]
Muscle spasm is a potential symptom of Long COVID in the World Health Organization's definition.[6]
Notable studies[edit | edit source]
Possible causes[edit | edit source]
Muscle spasms can occur as a result of many different illnesses including:
- ME/CFS and other neurological illnesses[2][4]
- Gulf War Illness[1][4]:22
- Diabetes, thyroid or liver conditions[2]
Spasms can also be caused by
- injury
- dehydration
- prolonged exercise, especially in hot weather
- low levels of potassium, magnesium or calcium, which can result from using diuretics
- pregnancy
- nerve compression, particularly in the spine.[1][2]
Treatments[edit | edit source]
Drugs that treat spams are known as muscle relaxants or antispasmodics.[1]
The Canadian Consensus Criteria suggests treating muscle spasms in ME/CFS with:
The International Consensus Criteria primer for clinicians suggests using magnesium sulphate.[3]
Muscle spasms can also be treated with skeletal and muscle relaxants such as carisoprodol, metaxalone, methocarbamol, tizanidine, orphenadrine and cyclobenzaprine.[1]
Alternative drugs for muscle spasms include diazepam (Valium), and medical marijuana (cannabis), although this has less scientific evidence.[1]
See also[edit | edit source]
- Baclofen
- Muscle fasciculations (twitching without pain)
- Pain
- Muscle relaxants (category)
Learn more[edit | edit source]
- Muscle spasm - drugs.com
- Muscle cramp - drugs.com
References[edit | edit source]
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 "Muscle spasm (Involuntary Hypertonicity)". drugs.com. Retrieved February 20, 2021.
- ↑ 2.0 2.1 2.2 2.3 2.4 "Muscle cramp". drugs.com. Retrieved February 20, 2021.
- ↑ 3.0 3.1 Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), ISBN 978-0-9739335-3-6
- ↑ 4.0 4.1 4.2 4.3 Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, AC Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF). Journal of Chronic Fatigue Syndrome. 11 (2): 7–115. doi:10.1300/J092v11n01_02.
- ↑ Fukuda, K.; Straus, S.E.; Hickie, I.; Sharpe, M.C.; Dobbins, J.G.; Komaroff, A. (December 15, 1994). "The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group" (PDF). Annals of Internal Medicine. American College of Physicians. 121 (12): 953–959. ISSN 0003-4819. PMID 7978722.
- ↑ Soriano, Joan B.; Allan, Maya; Alsokhn, Carine; Alwan, Nisreen A.; Askie, Lisa; Davis, Hannah E.; Diaz, Janet V.; Dua, Tarun; de Groote, Wouter; Jakob, Robert; Lado, Marta; Marshall, John; Murthy, Srin; Preller, Jacobus; Relan, Pryanka; Schiess, Nicoline; Seahwag, Archana (October 6, 2021), A clinical case definition of post COVID-19 condition by a Delphi consensus, World Health Organization (WHO) clinical case definition working group on post COVID-19 condition, World Health Organization
