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Mononucleosis
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==Trigger for chronic fatigue syndrome== A minority of infectious mononucleosis patients develop [[postviral fatigue syndrome]] and meet the criteria for [[chronic fatigue syndrome]] (CFS). Research studies cite figures from 7% to 13% of healthy people who contract infectious mononucleosis will have the illness progress into chronic fatigue syndrome (CFS).<ref name="Jason, Katz, 2017">{{Citation | last1 = Jason | first1 = Leonard A | authorlink1 = Leonard Jason | last2 = Katz | first2 = Ben | authorlink2 = Ben Katz | last3 = Gleason | first3 = Kristen | authorlink3 = Kirsten Gleason | last4 = McManimen | first4 = Stephanie | authorlink4 = Stephanie McManimen | last5 = Sunnquist | first5 = Madison | authorlink5 = Madison Sunnquist | last6 = Thorpe | first6 = Taylor | authorlink6 = Taylor Thorpe | title = A Prospective Study of Infectious Mononucleosis in College Students | journal = International Journal of Psychiatry | volume = 2 | issue = 1 | page = | date = 2017 | doi = | url = https://www.researchgate.net/profile/Leonard_Jason/publication/312936696_A_prospective_study_of_Infectious_Mononucleosis_in_college_students/links/588a23cc92851c2779b2568c/A-prospective-study-of-Infectious-Mononucleosis-in-college-students.pdf }}</ref><ref name="Buchwald, 2000">{{Citation | last1 = Buchwald | first1 = Dedra S | authorlink1 = Dedra Buchwald | last2 = Rea | first2 = Thomas | authorlink2 = Thomas Rea | last3 = Katon | first3 = Wayne J | authorlink3 = Wayne Katon | last4 = Russo | first4 = Joan E | authorlink4 = Joan Russo | last5 = Morrow | first5 = Rhoda Ashley | authorlink5 = Rhoda Ashley Morrow | title = Acute infectious mononucleosis: Characteristics of patients who report failure to recover | journal = The American Journal of Medicine | volume = 109 | issue = 7 | page = 531-7 | date = 2000 | pmid = | doi = 10.1016/S0002-9343(00)00560-X }}</ref><ref name=":0" /><ref>{{Cite journal | last = Lennon | first = P. | authorlink = | last2 = Crotty | first2 = M. | authorlink2 = | last3 = Fenton | first3 = J.E. | authorlink3 = | date = 2015-04-21 | title = Infectious mononucleosis|url=https://www.researchgate.net/profile/Paul_Lennon/publication/275522485_Infectious_mononucleosis/links/5551166808ae739bdb92056b.pdf | journal=BMJ|language=en|volume=350|issue=h1825 | pages = 6|doi=10.1136/bmj.h1825|issn=1756-1833|pmc=|pmid=|access-date=|quote=|via=}}</ref> In a 2013 study by [[Leonard Jason|Jason]] and [[Ben Katz|Katz]], thirteen percent of adolescents (mainly female) met the criteria for CFS 6 months following infectious mononucleosis; the figure was 7% at 12 months and 4% at 24 months. A year later, Jason and Katz looked at numerous medical, demographic, and psychological factors in an effort to find predictors of which infectious mononucleosis patients would develop chronic fatigue syndrome. They found the best predictor was the illness severity of the case of infectious mononucleosis.<ref name="Jason, Katz, 2014">{{Citation | last1 = Jason | first1 = Leonard A | authorlink1 = Leonard Jason | last2 = Katz | first2 = Ben Z. | authorlink2 = Ben Katz | last3 = Shiraishi | first3 = Yukiko| authorlink3 = Yukiko Shiraishi | last4 = Mears | first4 = Cynthia J. | authorlink4 = Cynthia Mears | last5 = Im | first5 = Young | authorlink5 = Young Im | last6 = Taylor | first6 = Renee R. | authorlink6 = Renee Taylor | title = Predictors of post-infectious chronic fatigue syndrome in adolescents | journal = Health Psychology and Behavioral Medicine | volume = 2 | issue = 1 | page = 41-51 | date = 2014 | doi = 10.1080/21642850.2013.869176 }}</ref> In 2019, Katz et al. found that severity of mononucleosis predicted risk of CFS six months post-infection.<ref name=":0" />
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