Mold hypothesis: Difference between revisions

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
(ron davis interview)
(→‎Research: difficulties)
Line 7: Line 7:


== Research ==
== Research ==
In 2019 Professor [[Ronald Davis|Ron Davis]] said that his group was considering conducting experiments to explore the possible role of mold in ME/CFS, and suggested it needed to be explored.<ref>{{Cite web|url=https://paradigmchange.me/wp/davis/|title=Stanford Professor Ron Davis Discusses ME/CFS and Toxic Mold Issues|last=Foundry|first=The Theme|website=Paradigm Change|language=en-US|access-date=2022-08-03}}</ref>
In 2019 Professor [[Ronald Davis|Ron Davis]] said that his group was considering conducting experiments to explore the possible role of mold in ME/CFS, and suggested it needed to be explored. However he noted difficulties with complexity and funding.<ref>{{Cite web|url=https://paradigmchange.me/wp/davis/|title=Stanford Professor Ron Davis Discusses ME/CFS and Toxic Mold Issues|last=Foundry|first=The Theme|website=Paradigm Change|language=en-US|access-date=2022-08-03}}</ref>


==Notable studies==
==Notable studies==

Revision as of 11:00, August 3, 2022

The mold hypothesis is the hypothesis that mold exposure is implicated in the onset of ME/CFS, or in perpetuating or worsening it. It came to prominence by discovery of toxic mold in the clusters of "mystery malady" that had baffled the CDC into creating the Chronic fatigue Syndrome.[citation needed]

Evidence[edit | edit source]

The evidence was found by school authorities and testing by mold remediation companies after CFS researchers failed to locate literature and proper testing for toxic mold, and had prematurely concluded that the clusters of illness must be solely due to viral causes.[citation needed]

In 2013 a study of 112 CFS patients found 93% were positive for at least one mycotoxin. In the study, this was compared to a previously tested group of healthy controls without a history of exposure to water damaged buildings or a moldy environment, where no positive cases were found.[1] The study was criticized in letters to the journal for the choice of the comparison group, because specifically choosing a comparison group without a history of mold exposure could bias the study towards finding more mycotoxins in the CFS group.[2][3] The authors replied saying that their study was just a clinical observation study, and that it was useful for hypothesis generation for future studies.[4][5]

Research[edit | edit source]

In 2019 Professor Ron Davis said that his group was considering conducting experiments to explore the possible role of mold in ME/CFS, and suggested it needed to be explored. However he noted difficulties with complexity and funding.[6]

Notable studies[edit | edit source]

  • 2013, Detection of mycotoxins in patients with chronic fatigue syndrome[7] (Full Text)

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Brewer, Joseph H.; Thrasher, Jack D.; Straus, David C.; Madison, Roberta A.; Hooper, Dennis (April 11, 2013). "Detection of Mycotoxins in Patients with Chronic Fatigue Syndrome". Toxins. 5 (4): 605–617. doi:10.3390/toxins5040605. ISSN 2072-6651. PMC 3705282. PMID 23580077.
  2. Mendell, Mark J. (November 7, 2016). "Comment on Detection of Mycotoxins in Patients with Chronic Fatigue Syndrome Toxins 2013, 5, 605–617". Toxins. 8 (11): 324. doi:10.3390/toxins8110324. ISSN 2072-6651. PMC 5127121. PMID 27827984.
  3. Osterman, John W. (November 7, 2016). "Comment on Detection of Mycotoxins in Patients with Chronic Fatigue Syndrome. Toxins 2013, 5, 605–617". Toxins. 8 (11): 322. doi:10.3390/toxins8110322. ISSN 2072-6651. PMC 5127119. PMID 27827982.
  4. Brewer, Joseph; Thrasher, Jack Dwayne; Hooper, Dennis (November 7, 2016). "Reply to Comment on Detection of Mycotoxin in Patients with Chronic Fatigue Syndrome. Toxins 2013, 5, 605-617 by Mark J. Mendell". Toxins. 8 (11): 325. doi:10.3390/toxins8110325. ISSN 2072-6651. PMC 5127122. PMID 27827985.
  5. Brewer, Joseph; Thrasher, Jack Dwayne; Hooper, Dennis (November 7, 2016). "Reply to Comment on Detection of Mycotoxins in Patients with Chronic Fatigue Syndrome Toxins 2013, 5, 605–617 by John W. Osterman, M.D." Toxins. 8 (11): 323. doi:10.3390/toxins8110323. ISSN 2072-6651. PMC 5127120. PMID 27827983.
  6. Foundry, The Theme. "Stanford Professor Ron Davis Discusses ME/CFS and Toxic Mold Issues". Paradigm Change. Retrieved August 3, 2022.
  7. Brewer, Joseph H.; Thrasher, Jack D.; Straus, David C.; Madison, Roberta A.; Hooper, Dennis (2013), "Detection of Mycotoxins in Patients with Chronic Fatigue Syndrome", Toxins, 5 (4): 605-617, doi:10.3390/toxins5040605