Michael Houghton

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Source:ualberta.ca

Michael Houghton, PhD, is a Professor at the Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, Alberta, Canada. He was the first to successfully identify and clone the Hepatitis C virus.[1] His professional interests are the Hepatitis C virus, the Hepatitis B virus, and exploring if other chronic illnesses are caused or exacerbated by an acute or persistent viral infection.[2]

Dr. Houghton and his virology team are working on a biomarker for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) using diagnostic cytokine patterns (specifically circulating interleukin (IL)-16, IL-7, and Vascular Endothelial Growth Factor A (VEGF-A).[3] The team is also investigating if a novel pathogen is associated with a cluster of CFS patients.[4]

Awards[edit | edit source]

  • Canada Excellence Research Chair in Virology at the University of Alberta[5]
  • 2000, Albert Lasker Clinical Medical Research Award[6]

Chronic Fatigue Syndrome Advisory Committee[edit | edit source]

Dr. Houghton served as a voting member of the Chronic Fatigue Syndrome Advisory Committee from 05/10/10 to 05/10/14.[7]

Notable studies[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]


References[edit | edit source]

  1. ↑ http://www.cerc.gc.ca/chairholders-titulaires/houghton-eng.aspx
  2. ↑ http://www.mmi.med.ualberta.ca/staff_students/michael_houghton.php
  3. ↑ 3.0 3.1 Landi, Abdolamir; Broadhurst, David; Vernon, Suzanne D.; Tyrrell, D. Lorne J.; Houghton, Michael (February 2016). "Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome". Cytokine. 78: 27–36. doi:10.1016/j.cyto.2015.11.018.
  4. ↑ http://solvecfs.org/research/cfidsaa-research-program-for-researchers/michael-houghton/
  5. ↑ http://www.mmi.med.ualberta.ca/staff_students/michael_houghton.php
  6. ↑ http://www.laskerfoundation.org/awards/
  7. ↑ HHS.gov (2010), October 12 & 13, 2010 CFSAC Meeting (PDF) (Roster)
  8. ↑ Steffen, Imke; Tyrrell, D. Lorne; Stein, Eleanor; Montalvo, Leilani; Lee, Tzong-Hae; Zhou, Yanchen; Lu, Kai; Switzer, William M.; Tang, Shaohua; Jia, Hongwei; Hockman, Darren; Santer, Deanna M.; Logan, Michael; Landi, Amir; Law, John; Houghton, Michael; Simmons, Graham (November 17, 2011). "No Evidence for XMRV Nucleic Acids, Infectious Virus or Anti-XMRV Antibodies in Canadian Patients with Chronic Fatigue Syndrome". PLoS ONE. 6 (11): e27870. doi:10.1371/journal.pone.0027870. ISSN 1932-6203. PMC 3219700. PMID 22114717.
  9. ↑ Jason, LA; Unger, ER; Dimitrakoff, JD; Fagin, AP; Houghton, M; Cook, DB; Marshall, GD, Jr; Klimas, N; Snell, C (2012), "Minimum data elements for research reports on CFS", Brain, Behavior, Immunology, 26 (3): 401-6, doi:10.1016/j.bbi.2012.01.014, PMID 22306456

chronic illness any long-term illness, regardless of the severity. Chronic illnesses are typically incurable, requiring long-term management.

antibodies Antibody/immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

cytokine any class of immunoregulatory proteins secreted by cells, especially immune cells. Cytokines are small proteins important in cell signaling that modulate the immune system. (Learn more: me-pedia.org)

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